HK1247192A1 - 吡啶或嘧啶衍生物 - Google Patents

吡啶或嘧啶衍生物

Info

Publication number
HK1247192A1
HK1247192A1 HK18106576.9A HK18106576A HK1247192A1 HK 1247192 A1 HK1247192 A1 HK 1247192A1 HK 18106576 A HK18106576 A HK 18106576A HK 1247192 A1 HK1247192 A1 HK 1247192A1
Authority
HK
Hong Kong
Prior art keywords
pyridine
pyrimidine derivatives
pyrimidine
derivatives
Prior art date
Application number
HK18106576.9A
Other languages
English (en)
Inventor
馬里烏斯•赫納
於爾根•維希曼
Original Assignee
豪夫邁．羅氏有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 豪夫邁．羅氏有限公司 filed Critical 豪夫邁．羅氏有限公司
Publication of HK1247192A1 publication Critical patent/HK1247192A1/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
HK18106576.9A 2015-10-28 2018-05-21 吡啶或嘧啶衍生物 HK1247192A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP15191887 2015-10-28
PCT/EP2016/075590 WO2017072083A1 (en) 2015-10-28 2016-10-25 Pyridine or pyrimidine derivatives

Publications (1)

Publication Number Publication Date
HK1247192A1 true HK1247192A1 (zh) 2018-09-21

Family

ID=54360941

Family Applications (1)

Application Number Title Priority Date Filing Date
HK18106576.9A HK1247192A1 (zh) 2015-10-28 2018-05-21 吡啶或嘧啶衍生物

Country Status (8)

Country Link
US (1) US10155741B2 (zh)
EP (1) EP3368522B1 (zh)
JP (1) JP6849668B2 (zh)
CN (1) CN107922381B (zh)
AR (1) AR106475A1 (zh)
HK (1) HK1247192A1 (zh)
TW (1) TW201718539A (zh)
WO (1) WO2017072083A1 (zh)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6518789B2 (ja) 2015-04-23 2019-05-22 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ 精神障害の処置において使用するためのテトラゾール誘導体
CN108137566B (zh) 2015-10-06 2021-05-25 豪夫迈·罗氏有限公司 三唑衍生物
WO2017133990A1 (en) 2016-02-02 2017-08-10 F. Hoffmann-La Roche Ag Pyrazol-pyridine derivatives as eaat3 inhibitors
JP6936257B2 (ja) 2016-05-27 2021-09-15 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ Ｅａａｔ３阻害剤としてのピラゾール化合物

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101821246B (zh) * 2007-10-04 2013-05-01 弗·哈夫曼-拉罗切有限公司 四唑取代的芳基酰胺衍生物及其用途
JP5592388B2 (ja) * 2008-10-31 2014-09-17 メルク・シャープ・アンド・ドーム・コーポレーション 疼痛治療用のｐ２ｘ３受容体アンタゴニスト技術分野
JP6518789B2 (ja) * 2015-04-23 2019-05-22 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ 精神障害の処置において使用するためのテトラゾール誘導体
CN107922391B (zh) * 2015-08-12 2020-09-25 豪夫迈·罗氏有限公司 吡啶和嘧啶衍生物

Also Published As

Publication number Publication date
JP6849668B2 (ja) 2021-03-24
EP3368522A1 (en) 2018-09-05
TW201718539A (zh) 2017-06-01
JP2018535926A (ja) 2018-12-06
AR106475A1 (es) 2018-01-17
WO2017072083A1 (en) 2017-05-04
CN107922381A (zh) 2018-04-17
EP3368522B1 (en) 2021-08-04
CN107922381B (zh) 2020-10-13
US10155741B2 (en) 2018-12-18
US20180258066A1 (en) 2018-09-13

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