HK1246828A1 - 用於檢測癌症的生物標志物組 - Google Patents

用於檢測癌症的生物標志物組

Info

Publication number
HK1246828A1
HK1246828A1 HK18105993.6A HK18105993A HK1246828A1 HK 1246828 A1 HK1246828 A1 HK 1246828A1 HK 18105993 A HK18105993 A HK 18105993A HK 1246828 A1 HK1246828 A1 HK 1246828A1
Authority
HK
Hong Kong
Prior art keywords
cancer
detection
biomarker panel
biomarker
panel
Prior art date
Application number
HK18105993.6A
Other languages
English (en)
Inventor
Barbara Burwinkel
Rongxi Yang
Andreas Schneeweiss
Original Assignee
Univ Heidelberg Ruprecht Karls
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Heidelberg Ruprecht Karls filed Critical Univ Heidelberg Ruprecht Karls
Publication of HK1246828A1 publication Critical patent/HK1246828A1/zh

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/106Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/118Prognosis of disease development
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/154Methylation markers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/178Oligonucleotides characterized by their use miRNA, siRNA or ncRNA

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Hospice & Palliative Care (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Oncology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
HK18105993.6A 2015-02-24 2018-05-09 用於檢測癌症的生物標志物組 HK1246828A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP15156389 2015-02-24
PCT/EP2016/053813 WO2016135168A1 (en) 2015-02-24 2016-02-24 Biomarker panel for the detection of cancer

Publications (1)

Publication Number Publication Date
HK1246828A1 true HK1246828A1 (zh) 2018-09-14

Family

ID=52589264

Family Applications (1)

Application Number Title Priority Date Filing Date
HK18105993.6A HK1246828A1 (zh) 2015-02-24 2018-05-09 用於檢測癌症的生物標志物組

Country Status (16)

Country Link
US (1) US10941451B2 (zh)
EP (1) EP3262190B1 (zh)
JP (2) JP6807873B2 (zh)
KR (1) KR20170120124A (zh)
CN (1) CN107406880A (zh)
AU (1) AU2016223532B2 (zh)
CA (1) CA2975952A1 (zh)
DK (1) DK3262190T3 (zh)
EA (1) EA037995B1 (zh)
ES (1) ES2893297T3 (zh)
HK (1) HK1246828A1 (zh)
IL (1) IL253756B (zh)
MX (1) MX2017010836A (zh)
PL (1) PL3262190T3 (zh)
UA (1) UA124612C2 (zh)
WO (1) WO2016135168A1 (zh)

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KR102100557B1 (ko) * 2017-06-21 2020-04-14 사회복지법인 삼성생명공익재단 대장암 환자의 항암제 치료 반응성 예측용 마커
WO2018236065A1 (ko) * 2017-06-21 2018-12-27 사회복지법인 삼성생명공익재단 대장암 환자의 항암제 치료 반응성 예측용 마커
CN110997915A (zh) * 2017-08-23 2020-04-10 国立研究开发法人国立癌研究中心 肝细胞癌的风险评价方法
WO2019081507A1 (en) 2017-10-23 2019-05-02 Universität Heidelberg NEW MARKERS DERIVED FROM BLOOD FOR CANCER DETECTION
JP7326764B2 (ja) * 2018-03-09 2023-08-16 東ソー株式会社 腫瘍マーカーならびに腫瘍細胞を夾雑細胞と区別して回収および検出する方法
US20220127678A1 (en) * 2019-02-21 2022-04-28 Universität Heidelberg Biomarker panel for diagnosis and prognosis of cancer
CN110136776B (zh) * 2019-05-15 2021-04-20 深圳大学 一种从低质量核糖体印迹数据预测基因编码框的方法和系统
CN110269869B (zh) * 2019-07-30 2023-03-31 宁夏医科大学 一种以蜥蜴为主的抗肿瘤药物及验证方法
CN112176419B (zh) * 2019-10-16 2022-03-22 中国医学科学院肿瘤医院 一种检测ctDNA中肿瘤特异基因的变异和甲基化的方法
CN113186279B (zh) * 2020-01-14 2024-07-02 腾辰生物科技(上海)有限公司 用于辅助诊断癌症的透明质酸酶甲基化标志物及试剂盒
CN118460718A (zh) * 2020-01-15 2024-08-09 腾辰生物科技(上海)有限公司 一种用于辅助诊断食管癌的钙结合蛋白甲基化标志物
CN113136428B (zh) * 2020-01-19 2024-04-19 腾辰生物科技(上海)有限公司 一种甲基化标志物在辅助诊断癌症中的应用
CN113215250B (zh) * 2020-02-04 2024-04-30 腾辰生物科技(上海)有限公司 一个基因的甲基化水平在辅助诊断癌症中的应用
CN113215251B (zh) * 2020-02-04 2024-04-26 腾辰生物科技(上海)有限公司 一种辅助诊断癌症的甲基化标志物
CN113528635B (zh) * 2020-04-16 2024-06-11 腾辰生物科技(上海)有限公司 一种印记基因的甲基化作为心脑血管疾病早期诊断的标志物
WO2022015532A1 (en) * 2020-07-13 2022-01-20 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Compositions and methods for detecting gene fusions of rad51ap1 and dyrk4 and for diagnosing and treating cancer
CN114480630B (zh) * 2020-10-26 2024-09-06 腾辰生物科技(上海)有限公司 用于辅助诊断癌症的一种甲基化标志物
WO2022170133A1 (en) * 2021-02-04 2022-08-11 The Cleveland Clinic Foundation Micro rna liver cancer markers and uses thereof
JP7143480B1 (ja) * 2021-06-10 2022-09-28 株式会社大一商会 遊技機

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US20030211606A1 (en) * 2002-05-10 2003-11-13 Isis Pharmaceuticals Inc. Antisense modulation of DYRK4 expression
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WO2012175562A2 (en) * 2011-06-21 2012-12-27 University Of Tartu Methylation and microrna markers of early-stage non-small cell lung cancer
US10316367B2 (en) * 2012-06-21 2019-06-11 Ruprecht-Karls-Universität Heidelberg Circulating miRNAs as markers for breast cancer
EP2682477A1 (en) 2012-07-06 2014-01-08 National University of Ireland, Galway miR-181a and miR652 as oncologic biomarker of breast cancer
WO2014020048A1 (en) * 2012-07-31 2014-02-06 Ruprecht-Karls-Universität Heidelberg Hyal2 methylation and expression as a cancer marker
JP2014036637A (ja) * 2012-08-20 2014-02-27 Hitachi Chemical Co Ltd 癌の切除手術後の予後を判定するためのデータ分析方法

Also Published As

Publication number Publication date
JP6807873B2 (ja) 2021-01-13
ES2893297T3 (es) 2022-02-08
UA124612C2 (uk) 2021-10-20
BR112017018008A2 (pt) 2018-04-10
AU2016223532B2 (en) 2021-07-01
EP3262190A1 (en) 2018-01-03
EP3262190B1 (en) 2021-09-01
EA037995B1 (ru) 2021-06-21
WO2016135168A1 (en) 2016-09-01
JP2018509934A (ja) 2018-04-12
KR20170120124A (ko) 2017-10-30
US10941451B2 (en) 2021-03-09
DK3262190T3 (da) 2021-10-11
CA2975952A1 (en) 2016-09-01
AU2016223532A1 (en) 2017-08-17
EA201791578A1 (ru) 2018-02-28
JP2021052777A (ja) 2021-04-08
CN107406880A (zh) 2017-11-28
US20180245159A1 (en) 2018-08-30
IL253756B (en) 2021-04-29
IL253756A0 (en) 2017-09-28
MX2017010836A (es) 2018-02-09
PL3262190T3 (pl) 2021-12-20

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