HK1246330A1 - 蛋白質純化 - Google Patents

蛋白質純化

Info

Publication number
HK1246330A1
HK1246330A1 HK18105961.4A HK18105961A HK1246330A1 HK 1246330 A1 HK1246330 A1 HK 1246330A1 HK 18105961 A HK18105961 A HK 18105961A HK 1246330 A1 HK1246330 A1 HK 1246330A1
Authority
HK
Hong Kong
Prior art keywords
protein purification
purification
protein
Prior art date
Application number
HK18105961.4A
Other languages
English (en)
Inventor
M‧斯皮塔利
J‧西蒙斯
R‧懷特康比
M‧R‧皮爾斯-黑金斯
Original Assignee
Ucb醫藥有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ucb醫藥有限公司 filed Critical Ucb醫藥有限公司
Publication of HK1246330A1 publication Critical patent/HK1246330A1/zh

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/241Tumor Necrosis Factors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/16Extraction; Separation; Purification by chromatography
    • C07K1/18Ion-exchange chromatography
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/16Extraction; Separation; Purification by chromatography
    • C07K1/22Affinity chromatography or related techniques based upon selective absorption processes
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/30Extraction; Separation; Purification by precipitation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/30Extraction; Separation; Purification by precipitation
    • C07K1/306Extraction; Separation; Purification by precipitation by crystallization
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/36Extraction; Separation; Purification by a combination of two or more processes of different types
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/10Immunoglobulins specific features characterized by their source of isolation or production
    • C07K2317/14Specific host cells or culture conditions, e.g. components, pH or temperature
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55Fab or Fab'
HK18105961.4A 2010-07-27 2018-05-08 蛋白質純化 HK1246330A1 (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB1012603.5A GB201012603D0 (en) 2010-07-27 2010-07-27 Protein purification

Publications (1)

Publication Number Publication Date
HK1246330A1 true HK1246330A1 (zh) 2018-09-07

Family

ID=42752872

Family Applications (1)

Application Number Title Priority Date Filing Date
HK18105961.4A HK1246330A1 (zh) 2010-07-27 2018-05-08 蛋白質純化

Country Status (22)

Country Link
US (4) US9309280B2 (zh)
EP (2) EP3747893A1 (zh)
JP (1) JP5893622B2 (zh)
KR (1) KR101921767B1 (zh)
CN (2) CN103025752A (zh)
AU (1) AU2011284896B2 (zh)
BR (1) BR112013000623B1 (zh)
CA (1) CA2805132C (zh)
CY (1) CY1123619T1 (zh)
DK (1) DK2598514T3 (zh)
ES (1) ES2834967T3 (zh)
GB (1) GB201012603D0 (zh)
HK (1) HK1246330A1 (zh)
HU (1) HUE052159T2 (zh)
IL (1) IL223931A (zh)
LT (1) LT2598514T (zh)
PL (1) PL2598514T3 (zh)
PT (1) PT2598514T (zh)
RS (1) RS61095B1 (zh)
SG (2) SG186957A1 (zh)
SI (1) SI2598514T1 (zh)
WO (1) WO2012013682A2 (zh)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201012603D0 (en) * 2010-07-27 2010-09-08 Ucb Pharma Sa Protein purification
SG10201701224UA (en) * 2012-03-12 2017-04-27 Merck Patent Gmbh Removal of protein aggregates from biopharmaceutical preparations in a flowthrough mode
SG11201408502XA (en) * 2012-06-21 2015-01-29 Synthon Biopharmaceuticals Bv Method of purifying an antibody
EA030551B1 (ru) * 2013-01-09 2018-08-31 Шир Хьюман Дженетик Терапис, Инк. Способы очистки арилсульфатазы а
MX368142B (es) 2013-04-30 2019-09-20 Intas Pharmaceuticals Ltd Metodo de clonacion, expresion y purificacion novedoso para la preparacion de ranibizumab.
SG10201804200WA (en) 2013-12-12 2018-07-30 Emd Millipore Corp Protein separations using an acrylamide containing filter
BR112017013398B1 (pt) 2014-12-22 2023-12-05 Ucb Biopharma Sprl Método de fabricar anticorpo ou fragmento de ligação ao antígeno do mesmo
IL282614B2 (en) 2015-02-06 2024-02-01 Cell Idx Inc Antigen-conjugated immune reagents
MA45489A (fr) 2015-10-22 2018-08-29 Juno Therapeutics Gmbh Procédés de culture de cellules, kits et appareil associés
GB201602938D0 (en) * 2016-02-19 2016-04-06 Ucb Biopharma Sprl Protein purification
EP3485275A4 (en) * 2016-07-18 2020-06-17 Cell IDX, Inc. ANTIGEN-COUPLED HYBRIDIZATION REAGENTS
JP7339160B2 (ja) 2017-04-27 2023-09-05 ジュノ セラピューティクス ゲーエムベーハー オリゴマー粒子試薬およびその使用方法
US10717023B1 (en) * 2017-10-11 2020-07-21 Roddy Kevin Stafford Method for continuous purification
CN110241012B (zh) * 2018-03-09 2022-11-01 嘉和生物药业有限公司 一种生物大分子上游分阶段截留的生产方法、生产模块及在生产中的应用
WO2021176311A1 (en) * 2020-03-05 2021-09-10 Lupin Limited An improved purification process for ranibizumab
CN116802206A (zh) * 2020-12-28 2023-09-22 等离子体技术有限责任公司 用于生产规模的免疫球蛋白g分离系统和方法
US11926669B2 (en) 2022-05-30 2024-03-12 Hanall Biopharma Co., Ltd. Anti-FcRn antibody or antigen binding fragment thereof with improved stability

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US5118796A (en) * 1987-12-09 1992-06-02 Centocor, Incorporated Efficient large-scale purification of immunoglobulins and derivatives
US5655866A (en) 1995-03-20 1997-08-12 Bellanca; Joseph V. Method of folding a signature for use in bookbinding
ATE451391T1 (de) 1996-11-27 2009-12-15 Genentech Inc Affinitätsreinigung von polypeptid-proteinen auf einer matrix
CA2313246A1 (en) * 1997-12-24 1999-07-08 Takeda Chemical Industries, Ltd. Polypeptide, their production and use
ES2261589T3 (es) 1998-05-06 2006-11-16 Genentech, Inc. Composicion de anticuerpos anti-her2.
GB0013810D0 (en) 2000-06-06 2000-07-26 Celltech Chiroscience Ltd Biological products
US7323553B2 (en) * 2002-04-26 2008-01-29 Genentech, Inc. Non-affinity purification of proteins
EP1543038B2 (en) 2002-09-11 2020-08-05 Genentech, Inc. Protein purification
GB0224082D0 (en) 2002-10-16 2002-11-27 Celltech R&D Ltd Biological products
AT412785B (de) * 2003-12-04 2005-07-25 Kungl Andreas J Dr Gag-bindungsproteine
CN104610422A (zh) * 2005-03-11 2015-05-13 惠氏公司 弱分配层析的方法
CA2645739A1 (en) 2006-03-20 2007-09-27 Medarex, Inc. Protein purification
NZ596517A (en) * 2006-04-05 2013-06-28 Abbott Biotech Ltd Antibody purification
US20080000431A1 (en) 2006-06-29 2008-01-03 Stephen Longo Dog leash assembly
KR20140015166A (ko) 2007-10-30 2014-02-06 제넨테크, 인크. 양이온 교환 크로마토그래피에 의한 항체 정제
WO2009135656A1 (en) * 2008-05-06 2009-11-12 Lonza Biologics Plc. A method for the purification of antibodies using displacement chromatography
BRPI0919547A2 (pt) * 2008-10-20 2015-12-08 Abbott Lab anticorpos que se ligam a il-12 e métodos de purificação do mesmo
KR101722423B1 (ko) * 2008-10-20 2017-04-18 애브비 인코포레이티드 항체 정제 동안의 바이러스 불활성화
GB201012603D0 (en) * 2010-07-27 2010-09-08 Ucb Pharma Sa Protein purification

Also Published As

Publication number Publication date
US9309280B2 (en) 2016-04-12
KR20130131307A (ko) 2013-12-03
CN107793477A (zh) 2018-03-13
EP2598514B1 (en) 2020-09-09
SG10201802316VA (en) 2018-04-27
BR112013000623A2 (pt) 2016-05-24
CN103025752A (zh) 2013-04-03
JP5893622B2 (ja) 2016-03-23
SG186957A1 (en) 2013-02-28
US20220289832A1 (en) 2022-09-15
JP2013532673A (ja) 2013-08-19
US10189897B2 (en) 2019-01-29
WO2012013682A3 (en) 2012-05-18
HUE052159T2 (hu) 2021-04-28
US20190135909A1 (en) 2019-05-09
LT2598514T (lt) 2020-12-28
PT2598514T (pt) 2020-12-15
AU2011284896B2 (en) 2016-06-16
ES2834967T3 (es) 2021-06-21
DK2598514T3 (da) 2020-11-16
WO2012013682A2 (en) 2012-02-02
IL223931A (en) 2017-10-31
CA2805132C (en) 2020-01-14
EP3747893A1 (en) 2020-12-09
SI2598514T1 (sl) 2021-01-29
CA2805132A1 (en) 2012-02-02
KR101921767B1 (ko) 2018-11-23
AU2011284896A1 (en) 2013-01-24
US20160108119A1 (en) 2016-04-21
GB201012603D0 (en) 2010-09-08
US20130184439A1 (en) 2013-07-18
CY1123619T1 (el) 2022-03-24
PL2598514T3 (pl) 2021-03-08
BR112013000623B1 (pt) 2022-10-11
EP2598514A2 (en) 2013-06-05
RS61095B1 (sr) 2020-12-31
US11339214B2 (en) 2022-05-24

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