HK1245632A1 - 包含癌症干性抑制剂的组合物和用於治疗癌症的免疫治疗剂 - Google Patents

包含癌症干性抑制剂的组合物和用於治疗癌症的免疫治疗剂 Download PDF

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Publication number
HK1245632A1
HK1245632A1 HK18104905.6A HK18104905A HK1245632A1 HK 1245632 A1 HK1245632 A1 HK 1245632A1 HK 18104905 A HK18104905 A HK 18104905A HK 1245632 A1 HK1245632 A1 HK 1245632A1
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Hong Kong
Prior art keywords
cancer
immunotherapeutic agent
compositions
treating cancer
inhibitor
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HK18104905.6A
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English (en)
Chinese (zh)
Inventor
C‧J‧李
Y‧李
高媛
王宇新
J‧黄
H‧罗戈夫
J‧黃
H‧羅戈夫
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波士顿生物医药有限公司
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Publication of HK1245632A1 publication Critical patent/HK1245632A1/zh

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2818—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Furan Compounds (AREA)
HK18104905.6A 2015-06-03 2016-06-03 包含癌症干性抑制剂的组合物和用於治疗癌症的免疫治疗剂 HK1245632A1 (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201562170498P 2015-06-03 2015-06-03
US62/170,498 2015-06-03
US201562233081P 2015-09-25 2015-09-25
US62/233,081 2015-09-25
PCT/US2016/035721 WO2016196935A1 (en) 2015-06-03 2016-06-03 Compositions comprising a cancer stemness inhibitor and an immunotherapeutic agent for use in treating cancer

Publications (1)

Publication Number Publication Date
HK1245632A1 true HK1245632A1 (zh) 2018-08-31

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
HK18104905.6A HK1245632A1 (zh) 2015-06-03 2016-06-03 包含癌症干性抑制剂的组合物和用於治疗癌症的免疫治疗剂

Country Status (15)

Country Link
US (1) US20180140572A1 (https=)
EP (1) EP3302462A1 (https=)
JP (2) JP2018521979A (https=)
KR (1) KR20180015195A (https=)
CN (1) CN107847481A (https=)
AU (1) AU2016271475A1 (https=)
BR (1) BR112017026025A2 (https=)
CA (1) CA2988126A1 (https=)
EA (1) EA201792623A1 (https=)
HK (1) HK1245632A1 (https=)
IL (1) IL256052A (https=)
MX (1) MX2017015618A (https=)
PH (1) PH12017502195A1 (https=)
TW (1) TW201717935A (https=)
WO (1) WO2016196935A1 (https=)

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Also Published As

Publication number Publication date
US20180140572A1 (en) 2018-05-24
BR112017026025A2 (pt) 2018-08-14
KR20180015195A (ko) 2018-02-12
WO2016196935A1 (en) 2016-12-08
IL256052A (en) 2018-01-31
JP2020169223A (ja) 2020-10-15
TW201717935A (zh) 2017-06-01
PH12017502195A1 (en) 2018-06-04
JP2018521979A (ja) 2018-08-09
CN107847481A (zh) 2018-03-27
CA2988126A1 (en) 2016-12-08
MX2017015618A (es) 2018-08-15
AU2016271475A1 (en) 2017-12-21
EA201792623A1 (ru) 2018-04-30
EP3302462A1 (en) 2018-04-11

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