HK1245268A1 - 含氮雜環化合物的製造方法及其中間體 - Google Patents
含氮雜環化合物的製造方法及其中間體Info
- Publication number
- HK1245268A1 HK1245268A1 HK18104741.4A HK18104741A HK1245268A1 HK 1245268 A1 HK1245268 A1 HK 1245268A1 HK 18104741 A HK18104741 A HK 18104741A HK 1245268 A1 HK1245268 A1 HK 1245268A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- nitrogen
- heterocyclic compound
- containing heterocyclic
- production method
- compound
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/42—One nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/48—Two nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2015141034A JP6412471B2 (ja) | 2015-07-15 | 2015-07-15 | 含窒素複素環化合物の製造方法およびその中間体 |
| PCT/JP2016/070758 WO2017010535A1 (ja) | 2015-07-15 | 2016-07-14 | 含窒素複素環化合物の製造方法およびその中間体 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1245268A1 true HK1245268A1 (zh) | 2018-08-24 |
Family
ID=57758235
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK18104741.4A HK1245268A1 (zh) | 2015-07-15 | 2018-04-11 | 含氮雜環化合物的製造方法及其中間體 |
Country Status (21)
| Country | Link |
|---|---|
| US (2) | US10435377B2 (zh) |
| EP (1) | EP3323811B1 (zh) |
| JP (1) | JP6412471B2 (zh) |
| KR (1) | KR102032140B1 (zh) |
| CN (1) | CN107848987B (zh) |
| AU (1) | AU2016294197B2 (zh) |
| BR (1) | BR112018000759A2 (zh) |
| CA (1) | CA2992403C (zh) |
| DK (1) | DK3323811T3 (zh) |
| ES (1) | ES2729958T3 (zh) |
| HK (1) | HK1245268A1 (zh) |
| IL (1) | IL256809B (zh) |
| MX (1) | MX2018000459A (zh) |
| NZ (1) | NZ738953A (zh) |
| PL (1) | PL3323811T3 (zh) |
| RU (1) | RU2717830C2 (zh) |
| SG (1) | SG11201800245QA (zh) |
| TR (1) | TR201909774T4 (zh) |
| TW (1) | TWI711605B (zh) |
| WO (1) | WO2017010535A1 (zh) |
| ZA (1) | ZA201800269B (zh) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW202027749A (zh) | 2018-10-12 | 2020-08-01 | 日商富士軟片股份有限公司 | 急性骨髓性白血病用抗腫瘤劑 |
| CN112996515A (zh) * | 2018-10-31 | 2021-06-18 | 富士胶片株式会社 | 包含抗肿瘤剂的造粒物 |
| WO2020090969A1 (ja) * | 2018-10-31 | 2020-05-07 | 富士フイルム株式会社 | 抗腫瘍剤を含む医薬組成物の包装体 |
| TW202045174A (zh) | 2019-02-28 | 2020-12-16 | 日商富士軟片股份有限公司 | 組合醫藥 |
| KR20240128987A (ko) | 2021-12-30 | 2024-08-27 | 바이오메아 퓨전, 인크. | Flt3의 억제제로서의 피라진 화합물 |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8928839D0 (en) | 1989-12-21 | 1990-02-28 | Beecham Group Plc | Novel compounds |
| JP4460292B2 (ja) | 2001-10-17 | 2010-05-12 | ベーリンガー インゲルハイム ファルマ ゲゼルシャフト ミット ベシュレンクテル ハフツング ウント コンパニー コマンディトゲゼルシャフト | ピリミジン誘導体、これらの化合物を含む医薬組成物、その使用及びその調製方法 |
| SG137989A1 (en) | 2005-06-08 | 2008-01-28 | Rigel Pharmaceuticals Inc | Compositions and methods for inhibition of the JAK pathway |
| US20060281755A1 (en) | 2005-06-10 | 2006-12-14 | Baumann Christian A | Synergistic modulation of flt3 kinase using aminopyrimidines kinase modulators |
| US8071768B2 (en) * | 2005-06-10 | 2011-12-06 | Janssen Pharmaceutica, N.V. | Alkylquinoline and alkylquinazoline kinase modulators |
| US8404697B2 (en) | 2005-11-11 | 2013-03-26 | Boehringer Ingelheim International Gmbh | Quinazoline derivatives for the treatment of cancer diseases |
| JP4610668B2 (ja) | 2006-03-17 | 2011-01-12 | アムビト ビオスシエンセス コルポラチオン | 疾患を治療するためのイミダゾロチアゾール化合物 |
| EP2022785A1 (en) * | 2007-06-20 | 2009-02-11 | Bayer Schering Pharma Aktiengesellschaft | Alkynylpyrimidines as Tie2 kinase inhibitors |
| PT2252597E (pt) | 2008-02-01 | 2014-04-30 | Akinion Pharmaceuticals Ab | Derivados de pirazina e a sua utilização como inibidores da proteína cinase |
| PT2271670E (pt) | 2008-03-14 | 2014-11-28 | Allergan Inc | Ensaio imunobaseado da atividade do serotipo a da toxina botulínica |
| EA029131B1 (ru) | 2008-05-21 | 2018-02-28 | Ариад Фармасьютикалз, Инк. | Фосфорсодержащие производные в качестве ингибиторов киназы |
| KR101705158B1 (ko) | 2009-05-05 | 2017-02-09 | 다나-파버 캔서 인스티튜트 인크. | Ｅｇｆｒ 억제제 및 질환 치료방법 |
| US9290485B2 (en) | 2010-08-04 | 2016-03-22 | Novartis Ag | N-((6-amino-pyridin-3-yl)methyl)-heteroaryl-carboxamides |
| JP5956999B2 (ja) | 2010-11-01 | 2016-07-27 | セルジーン アヴィロミクス リサーチ， インコーポレイテッド | ヘテロアリール化合物およびその使用 |
| JP5957003B2 (ja) | 2010-11-10 | 2016-07-27 | セルジーン アヴィロミクス リサーチ， インコーポレイテッド | 変異体選択的ｅｇｆｒ阻害剤およびその使用 |
| US8703767B2 (en) | 2011-04-01 | 2014-04-22 | University Of Utah Research Foundation | Substituted N-(3-(pyrimidin-4-yl)phenyl)acrylamide analogs as tyrosine receptor kinase BTK inhibitors |
| RU2017112522A (ru) | 2011-05-04 | 2019-01-24 | ФОРМА ТиЭм, ЭлЭлСИ | Новые соединения и композиции для ингибирования nampt |
| JP2013157540A (ja) | 2012-01-31 | 2013-08-15 | Toshiba Corp | 半導体装置およびその製造方法 |
| JP5736507B2 (ja) * | 2012-04-17 | 2015-06-17 | 富士フイルム株式会社 | 含窒素複素環化合物またはその塩 |
| EP3059227B1 (en) | 2013-10-16 | 2019-06-26 | FUJIFILM Corporation | Salt of nitrogen-containing heterocyclic compound or crystal thereof, pharmaceutical composition, and flt3 inhibitor |
| KR20150056683A (ko) | 2013-11-15 | 2015-05-27 | (주) 제일피앤티 | 대전 방지 필름 및 이를 이용한 쉴드 백 |
| BR112017003186A2 (pt) | 2014-08-22 | 2017-11-28 | Fujifilm Corp | composição farmacêutica para tratamento de cancer positivo para mutação em flt3, inibidor de flt3 mutante e usos dos mesmos |
-
2015
- 2015-07-15 JP JP2015141034A patent/JP6412471B2/ja active Active
-
2016
- 2016-07-14 EP EP16824515.7A patent/EP3323811B1/en active Active
- 2016-07-14 WO PCT/JP2016/070758 patent/WO2017010535A1/ja active Application Filing
- 2016-07-14 BR BR112018000759-5A patent/BR112018000759A2/pt active Search and Examination
- 2016-07-14 TW TW105122147A patent/TWI711605B/zh active
- 2016-07-14 MX MX2018000459A patent/MX2018000459A/es unknown
- 2016-07-14 KR KR1020187000990A patent/KR102032140B1/ko active IP Right Grant
- 2016-07-14 TR TR2019/09774T patent/TR201909774T4/tr unknown
- 2016-07-14 CA CA2992403A patent/CA2992403C/en active Active
- 2016-07-14 CN CN201680041023.4A patent/CN107848987B/zh active Active
- 2016-07-14 ES ES16824515T patent/ES2729958T3/es active Active
- 2016-07-14 NZ NZ738953A patent/NZ738953A/en unknown
- 2016-07-14 PL PL16824515T patent/PL3323811T3/pl unknown
- 2016-07-14 DK DK16824515.7T patent/DK3323811T3/da active
- 2016-07-14 RU RU2018100967A patent/RU2717830C2/ru active
- 2016-07-14 SG SG11201800245QA patent/SG11201800245QA/en unknown
- 2016-07-14 AU AU2016294197A patent/AU2016294197B2/en active Active
-
2018
- 2018-01-09 IL IL256809A patent/IL256809B/en active IP Right Grant
- 2018-01-10 US US15/867,122 patent/US10435377B2/en active Active
- 2018-01-15 ZA ZA2018/00269A patent/ZA201800269B/en unknown
- 2018-04-11 HK HK18104741.4A patent/HK1245268A1/zh unknown
-
2019
- 2019-02-11 US US16/272,263 patent/US10562862B2/en active Active
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| HK1247205A1 (zh) | 烯丙基苯氧基環磷腈化合物及其製造方法 | |
| IL249009A0 (en) | A method for making a fused heterocyclic compound | |
| EP3156397A4 (en) | Nitrogen-containing heterocyclic compound | |
| IL283288B (en) | A method for the production of a new nitrogen-containing compound or a salt thereof and the production of an intermediate of a new nitrogen-containing compound or a salt thereof | |
| EP3144308A4 (en) | Nitrogen-containing heterocyclic compound | |
| GB2557741B (en) | Icariside compound, preperation method thereof, and application thereof | |
| HK1245268A1 (zh) | 含氮雜環化合物的製造方法及其中間體 | |
| IL264307B (en) | Production method for a pyrazole-amide compound | |
| EP3363796A4 (en) | PROCESS FOR PREPARING A HETEROCYCLIC COMPOUND | |
| HK1249105A1 (zh) | 含氮雜環化合物 | |
| SG11202004021RA (en) | Production method for dihydroxyindoles | |
| HUE057149T2 (hu) | Mikromolekula vegyület, eljárás szintézisére és alkalmazására | |
| IL250223A0 (en) | A method for the preparation of the pyrimidin-1-ol compound, and its intermediates | |
| EP3466932A4 (en) | PROCESS FOR PRODUCING BICYCLIC HETEROCYCLIC COMPOUND CONTAINING NITROGEN | |
| GB2555726B (en) | Urea production method | |
| GB201710285D0 (en) | Method for producing nitrogen-containing pentafluorosulfanylbenzene compound | |
| HUE055885T2 (hu) | Eljárás biogáz és legalább egy szerves vegyület egyidejû elõállítására | |
| IL263091B (en) | A method for the production of heterocyclic compounds | |
| EP3530645C0 (en) | METHOD FOR PRODUCING A NITROGEN-CONTAINING COMPOUND | |
| HUE041633T2 (hu) | Megfúrószerelvény és megfelelõ gyártási eljárás | |
| EP3246322A4 (en) | Furoxan compound, and manufacturing method for same | |
| EP3130581A4 (en) | Method for producing heterocyclic compound |