HK1244218A1 - 包括多不飽和游離脂肪酸的毫米膠囊配製品 - Google Patents

包括多不飽和游離脂肪酸的毫米膠囊配製品

Info

Publication number
HK1244218A1
HK1244218A1 HK18103751.3A HK18103751A HK1244218A1 HK 1244218 A1 HK1244218 A1 HK 1244218A1 HK 18103751 A HK18103751 A HK 18103751A HK 1244218 A1 HK1244218 A1 HK 1244218A1
Authority
HK
Hong Kong
Prior art keywords
fatty acids
free fatty
polyunsaturated free
millicapsule
formulations
Prior art date
Application number
HK18103751.3A
Other languages
English (en)
Inventor
Hironori Kubota
Etienne Thierry Charles Rogeau
Toru Amemiya
Julien Georges Meissonnier
Anders Gillis Holmén
Andreas Radevik
Hans Carlsson
Bengt Staffan Schantz
Original Assignee
Omthera Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Omthera Pharmaceuticals Inc filed Critical Omthera Pharmaceuticals Inc
Publication of HK1244218A1 publication Critical patent/HK1244218A1/zh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4816—Wall or shell material
    • A61K9/4825—Proteins, e.g. gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/009—Sachets, pouches characterised by the material or function of the envelope
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4833—Encapsulating processes; Filling of capsules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4891—Coated capsules; Multilayered drug free capsule shells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5052—Proteins, e.g. albumin
    • A61K9/5057—Gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pulmonology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
HK18103751.3A 2015-02-23 2018-03-19 包括多不飽和游離脂肪酸的毫米膠囊配製品 HK1244218A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP15305278 2015-02-23
PCT/US2016/018571 WO2016137825A1 (en) 2015-02-23 2016-02-19 Millicapsule formulations comprising polyunsaturated free fatty acids

Publications (1)

Publication Number Publication Date
HK1244218A1 true HK1244218A1 (zh) 2018-08-03

Family

ID=52633188

Family Applications (1)

Application Number Title Priority Date Filing Date
HK18103751.3A HK1244218A1 (zh) 2015-02-23 2018-03-19 包括多不飽和游離脂肪酸的毫米膠囊配製品

Country Status (16)

Country Link
US (1) US10512611B2 (zh)
EP (1) EP3261622A4 (zh)
JP (1) JP6469261B2 (zh)
KR (2) KR20190090087A (zh)
CN (1) CN107530284A (zh)
AU (1) AU2016223109B2 (zh)
CA (1) CA2975549C (zh)
CL (1) CL2017002131A1 (zh)
EA (1) EA035377B1 (zh)
HK (1) HK1244218A1 (zh)
IL (1) IL253697B (zh)
MA (1) MA41611A (zh)
MX (1) MX2017010716A (zh)
NZ (1) NZ734149A (zh)
WO (1) WO2016137825A1 (zh)
ZA (1) ZA201705620B (zh)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK2800563T3 (en) 2012-01-06 2018-10-08 Omthera Pharmaceuticals Inc DPA Enriched Compositions of Multi-Saturated Omega-3 Fatty Acids in Free Acid Form
CA3073946A1 (en) * 2017-08-25 2019-02-28 Struct Nutrition, Llc Compositions and methods for preventing, alleviating, and treating neurological injury following head trauma
CN109463762A (zh) * 2018-12-10 2019-03-15 瞿瀚鹏 Dha油脂组合物在软胶囊中的应用以及软胶囊及其制备方法
JP7315383B2 (ja) * 2019-06-27 2023-07-26 株式会社Ｓｃｒｅｅｎホールディングス インクジェット用水性組成物及び固体製剤
KR20230151363A (ko) * 2022-04-25 2023-11-01 유엠에스엔지니어링 주식회사 오메가 3 심리스 연질캡슐 제조방법

Family Cites Families (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59225115A (ja) 1983-06-06 1984-12-18 Ota Seiyaku Kk 青魚類から得た長鎖高度不飽和脂肪酸を含有する微細カプセル
JPS61126016A (ja) * 1984-11-22 1986-06-13 Toagosei Chem Ind Co Ltd 不飽和脂肪酸を内相物としたマイクロカプセル
DE4201178C2 (de) * 1992-01-17 1995-12-07 Alfatec Pharma Gmbh Verfahren zur Herstellung von Weichgelatinekapseln nach einem Tropfverfahren
JPH0753356A (ja) * 1993-08-16 1995-02-28 Morishita Jintan Kk 酸化され易い油性物質を内容物とするシームレスカプセルおよびその製造方法
GB9509764D0 (en) 1995-05-15 1995-07-05 Tillotts Pharma Ag Treatment of inflammatory bowel disease using oral dosage forms of omega-3 polyunsaturated acids
US5686106A (en) * 1995-05-17 1997-11-11 The Procter & Gamble Company Pharmaceutical dosage form for colonic delivery
DE69935995T3 (de) * 1998-10-15 2011-02-10 Dsm Ip Assets B.V. Polyungesättigen fettsäuren nährungsergänzung
WO2001015702A1 (fr) * 1999-08-31 2001-03-08 Chugai Seiyaku Kabushiki Kaisha Capsules molles
US7025984B1 (en) 2000-06-26 2006-04-11 The Procter & Gamble Company Compositions and methods for body weight management
US20040217549A1 (en) * 2003-05-01 2004-11-04 Justak John F. Hydrodynamic brush seal
GB0403247D0 (en) 2004-02-13 2004-03-17 Tillotts Pharma Ag A pharmaceutical composition
US7622137B2 (en) * 2004-05-21 2009-11-24 Accu-Break Technologies, Inc. Dosage forms contained within a capsule or sachet
CA2613474A1 (en) * 2005-06-20 2007-03-08 Elan Pharma International Limited Nanoparticulate and controlled release compositions comprising aryl-heterocyclic compounds
CN101287382A (zh) * 2005-07-07 2008-10-15 加拿大海洋营养食品有限公司 含有输送装置的食物制品及其制造方法
US20070134493A1 (en) 2005-12-08 2007-06-14 Kanji Meghpara Compositions and capsules with stable hydrophilic layers
US20070141211A1 (en) * 2005-12-16 2007-06-21 Solae, Llc Encapsulated Phospholipid-Stabilized Oxidizable Material
US7652068B2 (en) 2005-12-20 2010-01-26 Cenestra Llc Omega 3 fatty acid formulations
US20090304784A1 (en) 2006-07-28 2009-12-10 V. Mane Fils Seamless capsules containing high amounts of polyunsaturated fatty acids and a flavouring component
KR100758664B1 (ko) 2006-08-16 2007-09-13 (주)케비젠 불포화지방산 함유 마이크로캡슐의 제조방법, 이 방법에의해 제조된 마이크로캡슐 및 이를 포함하는 제품
CN101827531A (zh) * 2007-10-17 2010-09-08 荷兰联合利华有限公司 具有包衣的胶囊化的ω-3脂肪酸和/或ω-6脂肪酸和/或其酯
EA201200829A1 (ru) * 2008-01-10 2012-11-30 Такеда Фармасьютикал Компани Лимитед Состав капсулы
US20100062057A1 (en) * 2008-09-10 2010-03-11 Pronova BioPharma Norge AS. Formulation
JP6100526B2 (ja) 2009-05-01 2017-03-22 ユーエーエス・ラボラトリーズ・エルエルシー 変性疾患の予防および治療のための細菌組成物
CN102724972A (zh) * 2009-10-23 2012-10-10 普罗诺瓦生物医药挪威公司 脂肪酸油混合物的包衣胶囊和包衣片剂
ES2911670T3 (es) * 2011-05-27 2022-05-20 Sun Patent Trust Aparato, procedimiento y programa para decodificar imágenes en movimiento
JP2013084557A (ja) * 2011-07-21 2013-05-09 Rohm Co Ltd 照明装置
JP2014531444A (ja) 2011-09-15 2014-11-27 オムセラ・ファーマシューティカルズ・インコーポレイテッド 抗血小板療法に対する耐性を治療するか、逆転させるか、阻害するかまたは防止するための方法および組成物
WO2013059669A1 (en) 2011-10-21 2013-04-25 Omthera Pharmaceuticals, Inc. Methods and compositions for treating or preventing attention deficit hyperactivity disorder
DK2800563T3 (en) 2012-01-06 2018-10-08 Omthera Pharmaceuticals Inc DPA Enriched Compositions of Multi-Saturated Omega-3 Fatty Acids in Free Acid Form
ES2741560T3 (es) 2012-03-30 2020-02-11 Micelle Biopharma Inc Composiciones de ésteres de ácidos grasos omega-3
EP2846779A4 (en) 2012-05-07 2015-12-16 Omthera Pharmaceuticals Inc STATIN AND OMEGA-3 FATTY ACID COMPOSITIONS
PT3079667T (pt) * 2013-12-13 2019-10-10 Novartis Ag Formas de dosagem farmacêutica
CN103989666A (zh) * 2014-04-11 2014-08-20 浙江海洋学院 n-3多不饱和脂肪酸在治疗非酒精性脂肪肝病药物中的应用
WO2016069446A1 (en) 2014-10-28 2016-05-06 Omthera Pharmaceuticals Inc Methods for modulating plasma levels of lipoproteins
WO2016073335A1 (en) 2014-11-05 2016-05-12 Omthera Pharmaceuticals Inc. Methods of treatment
WO2016130417A1 (en) 2015-02-11 2016-08-18 Omthera Pharmaceuticals Inc Omega-3 fatty acid prodrug compounds and uses thereof

Also Published As

Publication number Publication date
US10512611B2 (en) 2019-12-24
ZA201705620B (en) 2019-06-26
MA41611A (fr) 2018-01-02
EP3261622A4 (en) 2018-12-19
CL2017002131A1 (es) 2018-04-13
AU2016223109B2 (en) 2018-10-04
CA2975549A1 (en) 2016-09-01
AU2016223109A1 (en) 2017-08-17
US20180325829A1 (en) 2018-11-15
WO2016137825A8 (en) 2017-08-31
MX2017010716A (es) 2018-03-16
KR20190090087A (ko) 2019-07-31
NZ734149A (en) 2018-08-31
EA035377B1 (ru) 2020-06-03
CA2975549C (en) 2019-04-02
JP6469261B2 (ja) 2019-02-13
EA201791766A1 (ru) 2018-03-30
JP2018505914A (ja) 2018-03-01
KR20170116153A (ko) 2017-10-18
CN107530284A (zh) 2018-01-02
IL253697B (en) 2020-08-31
EP3261622A1 (en) 2018-01-03
WO2016137825A1 (en) 2016-09-01
IL253697A0 (en) 2017-09-28

Similar Documents

Publication Publication Date Title
ZA201704820B (en) Process for increasing the stability of a composition comprising polyunsaturated omega-3 fatty acids
IL246275B (en) A lipid containing long-chain polyunsaturated fatty acids
EP3248599A4 (en) Omega-3 fatty acid self-emulsifying composition
SG11201610596PA (en) Lipid comprising docosapentaenoic acid
PT3294850T (pt) Ácidos gordos poli-insaturados de cadeia muito longa a partir de óleos naturais
ZA201700275B (en) Cleaning compositions containing high fatty acids
ZA201704821B (en) Process for increasing the stability of a composition comprising polyunsaturated omega-6 fatty acids
EP3062785A4 (en) Enteric soft capsules comprising polyunsaturated fatty acids
HK1244218A1 (zh) 包括多不飽和游離脂肪酸的毫米膠囊配製品
SG11201608217PA (en) Fatty acid composition and use thereof
SG11201803022TA (en) Compositions comprising fatty acids and their use
ZA201702754B (en) Compositions comprising zwitterionic ester ammonioalkanoates
EP3069615A4 (en) Fat containing polyunsaturated fatty acid
EP3208261A4 (en) Method for preparing glyceride type polyunsaturated fatty acids
HK1246182A1 (zh) 肌肉脂肪化抑制用組合物
IL271961A (en) The compositions containing thymoquinone and omega-3 fatty acids
HK1252244A1 (zh) 含游離多元不飽和脂肪酸組合物及其製造方法
PL3346980T3 (pl) Lipofilowe kompozycje kosmetyczne zawierające estry kwasu pelargonowego
EP3498809A4 (en) PROCESS FOR THE PREPARATION OF FATTY GLYCERIDE
FI20150044A (fi) Rasvahappokoostumus
EP3097911A4 (en) Metabolism-improving agent comprising rare fatty acid
EP3424338A4 (en) CHOCOLATE TYPE FOOD CONTAINING POLYUNSATURATED FATTY ACID
EP3200601A4 (en) Lecithin drying using fatty acids
KR102406166B9 (ko) 아무르불가사리 지방산을 유효성분으로 포함하는 면역 증강용 조성물
IL249842A0 (en) A lipid containing docosapentanoic acid