HK1222184A1 - 免疫原性肽綴合物及以之誘導抗流感治療性抗體應答的方法 - Google Patents

免疫原性肽綴合物及以之誘導抗流感治療性抗體應答的方法

Info

Publication number
HK1222184A1
HK1222184A1 HK16110325.7A HK16110325A HK1222184A1 HK 1222184 A1 HK1222184 A1 HK 1222184A1 HK 16110325 A HK16110325 A HK 16110325A HK 1222184 A1 HK1222184 A1 HK 1222184A1
Authority
HK
Hong Kong
Prior art keywords
inducing
antibody response
therapeutic antibody
peptide conjugate
immunogenic peptide
Prior art date
Application number
HK16110325.7A
Other languages
English (en)
Inventor
Robert F Garry
Russell B Wilson
Original Assignee
The Administrators Of The Tulane Educational Fund
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The Administrators Of The Tulane Educational Fund filed Critical The Administrators Of The Tulane Educational Fund
Publication of HK1222184A1 publication Critical patent/HK1222184A1/zh

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/16Antivirals for RNA viruses for influenza or rhinoviruses
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C07K16/1018Orthomyxoviridae, e.g. influenza virus
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K17/00Carrier-bound or immobilised peptides; Preparation thereof
    • C07K17/02Peptides being immobilised on, or in, an organic carrier
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/60Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031Proteins
    • A61K2039/6081Albumin; Keyhole limpet haemocyanin [KLH]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011Details
    • C12N2760/16011Orthomyxoviridae
    • C12N2760/16111Influenzavirus A, i.e. influenza A virus
    • C12N2760/16122New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011Details
    • C12N2760/16011Orthomyxoviridae
    • C12N2760/16111Influenzavirus A, i.e. influenza A virus
    • C12N2760/16134Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Communicable Diseases (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
HK16110325.7A 2013-03-14 2016-08-31 免疫原性肽綴合物及以之誘導抗流感治療性抗體應答的方法 HK1222184A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13/828,988 US9649375B2 (en) 2013-03-14 2013-03-14 Immunogenic peptide conjugate and method for inducing an anti-influenza therapeutic antibody response therewith
PCT/US2014/025968 WO2014160171A2 (en) 2013-03-14 2014-03-13 Immunogenic peptide conjugate and method for inducing an anti-influenza therapeutic antibody response therewith

Publications (1)

Publication Number Publication Date
HK1222184A1 true HK1222184A1 (zh) 2017-06-23

Family

ID=51527967

Family Applications (1)

Application Number Title Priority Date Filing Date
HK16110325.7A HK1222184A1 (zh) 2013-03-14 2016-08-31 免疫原性肽綴合物及以之誘導抗流感治療性抗體應答的方法

Country Status (12)

Country Link
US (3) US9649375B2 (zh)
EP (1) EP2970386A4 (zh)
JP (1) JP2016519061A (zh)
CN (1) CN105377876A (zh)
AR (1) AR095367A1 (zh)
AU (2) AU2014244071B2 (zh)
CA (1) CA2906519A1 (zh)
EA (1) EA030004B1 (zh)
HK (1) HK1222184A1 (zh)
MX (1) MX2015012399A (zh)
TW (2) TW201925238A (zh)
WO (1) WO2014160171A2 (zh)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3568157A4 (en) * 2017-01-13 2021-01-06 National Research Council of Canada METHOD FOR OPTIMIZING THE PEPTIDE IMMUNO-EPITOP BY GLYCOSYLATION, OPTIMIZED PEPTIDE THEREOF AND ITS USE FOR CONJUGATE VACCINES
WO2018237010A2 (en) 2017-06-20 2018-12-27 The Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College VACCINE COMPOSITIONS AGAINST STREPTOCOCCUS AND THEIR METHODS OF USE
CN114516907B (zh) * 2020-11-20 2024-03-29 中国科学技术大学 一种植物抗逆性相关基因atagl70及其编码蛋白与应用

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL98845A0 (en) 1990-07-19 1992-07-15 Merck & Co Inc Coconjugate vaccines comprising immunogenic protein,hiv related peptides,and anionic moieties,their preparation and pharmaceutical compositions containing them
US6277969B1 (en) 1991-03-18 2001-08-21 New York University Anti-TNF antibodies and peptides of human tumor necrosis factor
US6800738B1 (en) 1991-06-14 2004-10-05 Genentech, Inc. Method for making humanized antibodies
US5824307A (en) 1991-12-23 1998-10-20 Medimmune, Inc. Human-murine chimeric antibodies against respiratory syncytial virus
US5589174A (en) * 1992-09-17 1996-12-31 Takara Shuzo Co., Ltd. Anti-human influenza virus antibody
US6479055B1 (en) * 1993-06-07 2002-11-12 Trimeris, Inc. Methods for inhibition of membrane fusion-associated events, including respiratory syncytial virus transmission
IL136544A0 (en) 1997-12-05 2001-06-14 Scripps Research Inst Humanization of murine antibody
ATE419869T1 (de) * 1999-08-19 2009-01-15 Dynavax Tech Corp Methode zur modulierung eines immunantwortes mit immunstimulierenden sequencen und zusammensetzungen dafür
US7189800B2 (en) * 2001-03-27 2007-03-13 Samuel Bogoch Replikin peptides in rapid replication of glioma cells and in influenza epidemics
US7456260B2 (en) 2002-06-17 2008-11-25 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Humanized antibody
DK2261375T3 (da) * 2003-11-04 2013-04-22 Univ Tulane Fremgangsmåde til hindring af viruscellefusion ved hæmning af funktionen af fusionsinitieringsområdet i RNA-vira med klasse I membranfusogene kappeproteiner
PT1937301E (pt) * 2005-10-18 2015-09-14 Novavax Inc Partículas idênticas a vírus (vlps) da gripe funcionais
EP1948227A4 (en) 2005-10-26 2010-03-31 Protelix Inc COMBINATORY ANTIGEN VACCINE AGAINST FLU
US8222204B2 (en) * 2006-05-03 2012-07-17 The Administrators of the Tulane Educational Fund and Autoimmune Technologies, LLC Influenza inhibiting compositions and methods
KR20090024748A (ko) 2006-05-31 2009-03-09 아스텔라스세이야쿠 가부시키가이샤 인간화 항인간 오스테오폰틴 항체
EA017957B1 (ru) * 2007-06-25 2013-04-30 Дзе Администрейторс Оф Дзе Тьюлейн Эдьюкейшнл Фанд Композиции и способы, ингибирующие грипп
EP2265646B1 (en) * 2008-03-12 2016-01-27 Her Majesty, The Queen in Right of Canada, as Represented by The Minister of Health Reagents and methods for detecting influenza virus proteins
WO2010117786A1 (en) 2009-03-30 2010-10-14 Mount Sinai School Of Medicine Of New York University Influenza virus vaccines and uses thereof
CA2760392C (en) 2009-04-29 2020-07-28 Her Majesty The Queen In Right Of Canada As Represented By The Minister Of Health Influenza viral peptides and fusion protein for immunization, methods and uses thereof
WO2010124393A1 (en) 2009-04-30 2010-11-04 National Research Council Of Canada Anticancer agent comprising a yatapoxvirus mutant and uses thereof
NZ596032A (en) 2009-05-11 2013-09-27 Crucell Holland Bv Human binding molecules capable of neutralizing influenza virus h3n2 and uses thereof
WO2011094363A2 (en) * 2010-01-26 2011-08-04 The Regents Of The University Of Colorado Influenza virus compositions and methods for universal vaccines
ES2608321T3 (es) 2011-07-14 2017-04-07 Janssen Vaccines & Prevention B.V. Moléculas de unión humanas capaces de neutralizar virus de la gripe A del grupo filogenético 1 y del grupo filogenético 2 y virus de la gripe B

Also Published As

Publication number Publication date
AU2014244071A1 (en) 2015-10-29
US20170258902A1 (en) 2017-09-14
EP2970386A4 (en) 2016-10-26
JP2016519061A (ja) 2016-06-30
CA2906519A1 (en) 2014-10-02
US20140271650A1 (en) 2014-09-18
CN105377876A (zh) 2016-03-02
TW201925238A (zh) 2019-07-01
AU2014244071B2 (en) 2018-07-05
AU2018241125A1 (en) 2018-10-25
WO2014160171A3 (en) 2015-04-23
EP2970386A2 (en) 2016-01-20
US10537634B2 (en) 2020-01-21
MX2015012399A (es) 2016-03-03
US20190054168A1 (en) 2019-02-21
US9649375B2 (en) 2017-05-16
US10137194B2 (en) 2018-11-27
TWI654205B (zh) 2019-03-21
EA201591747A1 (ru) 2016-02-29
WO2014160171A2 (en) 2014-10-02
TW201514208A (zh) 2015-04-16
EA030004B1 (ru) 2018-06-29
AR095367A1 (es) 2015-10-14

Similar Documents

Publication Publication Date Title
IL274881A (en) Anti-EGFR antibody and drug conjugate formulations
HK1223544A1 (zh) 抗體製劑和方法
HK1223301A1 (zh) 基於鼻內遞送中和抗體以增强治療效力的組合物和方法
EP2968743A4 (en) DEVICE AND METHOD FOR SETTING THERAPEUTIC PARAMETERS FOR AN INFUSION DEVICE
SG11201507883SA (en) Wt1-antigen peptide conjugate vaccine
HK1222331A1 (zh) 修飾的繆勒抑制物質 蛋白及其用於疾病治療的用途
HK1247091A1 (zh) 治療抗體及其用途
PL2986633T3 (pl) Sposoby ekspresji peptydów i białek
ZA201508861B (en) Timing adjustment method and device
HK1204301A1 (zh) 抗原傳送裝置和方法
HK1212713A1 (zh) 抗體的治療性用途
ZA201607581B (en) Dosage forms and therapeutic uses l-4lchlorokynurenine
GB201318840D0 (en) Method and device for protein preparation
EP3007661A4 (en) Methods and apparatus for therapeutic device
HK1222184A1 (zh) 免疫原性肽綴合物及以之誘導抗流感治療性抗體應答的方法
SG11201508545QA (en) Drug administering device and assembly method therefore
SG11201507494PA (en) Anterior capsulotomy device and procedure
IL227344A0 (en) A method for increasing drug effectiveness and reducing side effects
GB201301072D0 (en) Therapeutic Moisturiser
GB201300778D0 (en) Therapeutic moisturiser
GB201318195D0 (en) Protein monitor and correcting device
GB201312164D0 (en) Assisting device for mobility challenged individuals
AU2013904778A0 (en) Apparatus for producing therapeutically active proteins and uses thereof