HK1220381A1 - 用於藥物戒斷的非毒性治療方法 - Google Patents

用於藥物戒斷的非毒性治療方法

Info

Publication number
HK1220381A1
HK1220381A1 HK16108510.6A HK16108510A HK1220381A1 HK 1220381 A1 HK1220381 A1 HK 1220381A1 HK 16108510 A HK16108510 A HK 16108510A HK 1220381 A1 HK1220381 A1 HK 1220381A1
Authority
HK
Hong Kong
Prior art keywords
drug withdrawal
toxic treatment
toxic
treatment
withdrawal
Prior art date
Application number
HK16108510.6A
Other languages
English (en)
Inventor
Lawrence Friedhoff
Original Assignee
Demerx Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Demerx Inc filed Critical Demerx Inc
Publication of HK1220381A1 publication Critical patent/HK1220381A1/zh

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/485Morphinan derivatives, e.g. morphine, codeine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32Alcohol-abuse
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36Opioid-abuse
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
HK16108510.6A 2013-03-15 2016-07-19 用於藥物戒斷的非毒性治療方法 HK1220381A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361852485P 2013-03-15 2013-03-15
PCT/US2014/028946 WO2014144508A2 (en) 2013-03-15 2014-03-14 Method for non-toxic treatment for drug withdrawal

Publications (1)

Publication Number Publication Date
HK1220381A1 true HK1220381A1 (zh) 2017-05-05

Family

ID=51537436

Family Applications (1)

Application Number Title Priority Date Filing Date
HK16108510.6A HK1220381A1 (zh) 2013-03-15 2016-07-19 用於藥物戒斷的非毒性治療方法

Country Status (14)

Country Link
US (3) US20140288056A1 (zh)
EP (1) EP2968355A4 (zh)
JP (1) JP2016514679A (zh)
KR (1) KR20150130461A (zh)
CN (1) CN105307658A (zh)
AR (1) AR095338A1 (zh)
AU (1) AU2014228986A1 (zh)
BR (1) BR112015022465A2 (zh)
CA (2) CA2942638A1 (zh)
EA (1) EA201591679A1 (zh)
HK (1) HK1220381A1 (zh)
TW (1) TW201505634A (zh)
WO (2) WO2014143201A1 (zh)
ZA (1) ZA201507514B (zh)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008036540A2 (en) 2006-09-20 2008-03-27 Boehringer Ingelheim International Gmbh Rho kinase inhibitors
WO2014143201A1 (en) 2013-03-15 2014-09-18 Demerx, Inc. Method for noribogaine treatment of addiction in patients on methadone
WO2015126836A2 (en) * 2014-02-18 2015-08-27 Demerx, Inc. Therapeutic methods employing noribogaine and related compounds
JP2017509612A (ja) 2014-02-18 2017-04-06 デメルクス,インコーポレイテッド 薬物中毒の急性および長期間での治療方法。
US9561232B2 (en) 2014-02-18 2017-02-07 Demerx, Inc. Low dose noribogaine for treating nicotine addiction and preventing relapse of nicotine use
US9591978B2 (en) 2014-03-13 2017-03-14 Demerx, Inc. Methods and compositions for pre-screening patients for treatment with noribogaine
US9549935B2 (en) 2014-07-14 2017-01-24 Demerx, Inc. Methods and compositions for treating migraines using noribogaine
US9592239B2 (en) 2014-09-12 2017-03-14 Demerx, Inc. Methods and compositions for ibogaine treatment of impulse control disorder, anxiety-related disorders, violence and/or anger, or regulating food intake
EP4279134A1 (en) 2014-11-26 2023-11-22 DemeRx, Inc. Methods and compostions for potentiating the action of opioid analgesics using iboga alkaloids
WO2016134019A1 (en) * 2015-02-19 2016-08-25 Demerx, Inc. Methods for treating disorders associated with undesired activity of neuronal nicotinic acetylcholine receptors
CA3024081A1 (en) * 2015-05-11 2016-11-17 Demerx, Inc. Methods for treatment of opioid dependency and withdrawal using noribogaine
EP3376870B1 (en) 2015-11-17 2021-08-11 Aerie Pharmaceuticals, Inc. Process for the preparation of kinase inhibitors and intermediates thereof
KR102409785B1 (ko) 2017-03-23 2022-06-16 삼성전자주식회사 무선 통신 시스템에서 초기 접속을 수행하기 위한 장치 및 방법
GB2571696B (en) 2017-10-09 2020-05-27 Compass Pathways Ltd Large scale method for the preparation of Psilocybin and formulations of Psilocybin so produced
EP3955918A1 (en) 2019-04-17 2022-02-23 COMPASS Pathfinder Limited Methods of treating neurocognitive disorders, chronic pain and reducing inflammation
US20220265675A1 (en) * 2019-07-15 2022-08-25 Demerx, Inc. Methods for the non-toxic treatment for opioid drug withdrawal combining noribogaine and cannabinoids

Family Cites Families (58)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2817623A (en) 1956-03-22 1957-12-24 Ciba Pharm Prod Inc Tabernanthine, ibogaine containing analgesic compositions
US4626539A (en) 1984-08-10 1986-12-02 E. I. Dupont De Nemours And Company Trandermal delivery of opioids
US4806341A (en) 1985-02-25 1989-02-21 Rutgers, The State University Of New Jersey Transdermal absorption dosage unit for narcotic analgesics and antagonists and process for administration
US5149538A (en) 1991-06-14 1992-09-22 Warner-Lambert Company Misuse-resistive transdermal opioid dosage form
ATE324897T1 (de) 1994-07-25 2006-06-15 Nda Int Inc Verwendung von noribogain derivaten zur behandlung von chemischer abhängigkeit bei säugern
US5591738A (en) 1994-10-14 1997-01-07 Nda International, Inc. Method of treating chemical dependency using β-carboline alkaloids, derivatives and salts thereof
US5616575A (en) 1995-12-04 1997-04-01 Regents Of The University Of Minnesota Bioactive tricyclic ibogaine analogs
IL134796A0 (en) 1997-09-04 2001-04-30 Novoneuron Inc Noribogaine in the treatment of pain and drug addiction
US7220737B1 (en) 1997-09-04 2007-05-22 Novoneuron, Inc Noribogaine in the treatment of pain and drug addiction
US6416793B1 (en) 2000-07-11 2002-07-09 Bioresponse, L.L.C. Formulations and use of controlled-release indole alkaloids
US20030153552A1 (en) 2002-02-14 2003-08-14 Mash Deborah C. Method of treating chemical dependency in mammals and a composition therefor
US6939538B2 (en) * 2002-04-11 2005-09-06 Biomedical Research Models, Inc. Extended release analgesic for pain control
US6933308B2 (en) 2002-12-20 2005-08-23 Bristol-Myers Squibb Company Aminoalkyl thiazole derivatives as KCNQ modulators
US20060229293A1 (en) 2005-04-06 2006-10-12 Addiction Research Institute, Inc. Compositions for the treatment of hepatitis C and methods for using compositions for the treatment of hepatitis C
US8362007B1 (en) 2010-05-11 2013-01-29 Demerx, Inc. Substituted noribogaine
US9394294B2 (en) 2010-05-11 2016-07-19 Demerx, Inc. Methods and compositions for preparing and purifying noribogaine
US8765737B1 (en) 2010-05-11 2014-07-01 Demerx, Inc. Methods and compositions for preparing and purifying noribogaine
US8741891B1 (en) 2010-06-22 2014-06-03 Demerx, Inc. N-substituted noribogaine prodrugs
US8637648B1 (en) 2010-06-22 2014-01-28 Demerx, Inc. Compositions comprising noribogaine and an excipient to facilitate transport across the blood brain barrier
US8802832B2 (en) 2010-06-22 2014-08-12 Demerx, Inc. Compositions comprising noribogaine and an excipient to facilitate transport across the blood brain barrier
US9586954B2 (en) 2010-06-22 2017-03-07 Demerx, Inc. N-substituted noribogaine prodrugs
JP6049615B2 (ja) 2010-07-23 2016-12-21 デマークス・インコーポレイテッドDemerx,Inc. ノリボガイン組成物
WO2012024401A2 (en) 2010-08-17 2012-02-23 University Of Florida Research Foundation, Inc. Intelligent drug and/or fluid delivery system to optimizing medical treatment or therapy using pharmacodynamic and/or pharmacokinetic data
US8648198B2 (en) 2011-01-19 2014-02-11 Cold Spring Harbor Laboratory Phenylethanolamine-based NMDA receptor antagonists
EP2481740B1 (en) 2011-01-26 2015-11-04 DemeRx, Inc. Methods and compositions for preparing noribogaine from voacangine
BR112013023847B1 (pt) 2011-03-18 2021-02-23 Alkermes Pharma Ireland Limited composições farmacêuticas compreendendo ésteres de sorbitano e uso das mesmas
US8742096B2 (en) 2011-03-28 2014-06-03 Demerx, Inc. Methods and compositions for preparing noribogaine from voacangine
US10702485B2 (en) 2011-07-09 2020-07-07 Syntrix Biosystems Inc. Compositions and methods for overcoming resistance to tramadol
PE20142353A1 (es) 2011-09-15 2015-01-10 Demerx Inc Ansolvatos de sal de noribogaina
EP2788355A4 (en) 2011-12-08 2015-10-21 Demerx Inc STEREOSELECTIVE TOTAL SYNTHESIS OF NORIBOGAIN
CA2855990A1 (en) * 2011-12-09 2013-06-13 Demerx, Inc. Sulfate esters of noribogaine
WO2013085922A1 (en) 2011-12-09 2013-06-13 Demerx, Inc. Phosphate esters of noribogaine
WO2013112622A1 (en) 2012-01-25 2013-08-01 Demerx, Inc. (1r,4r) 7-oxo-2-azabicyclo[2.2.2]oct-5-ene and derivatives thereof
WO2013112673A1 (en) 2012-01-25 2013-08-01 Demerx, Inc. Synthetic voacangine
US9150584B2 (en) 2012-01-25 2015-10-06 Demerx, Inc. Indole and benzofuran fused isoquinuclidene derivatives and processes for preparing them
EP2693223B8 (en) 2012-08-03 2021-09-08 ABB Schweiz AG Voltage measurement device with an insulating body
US9045481B2 (en) 2012-12-20 2015-06-02 Demerx, Inc. Substituted noribogaine
US8940728B2 (en) 2012-12-20 2015-01-27 Demerx, Inc. Substituted noribogaine
WO2014143201A1 (en) 2013-03-15 2014-09-18 Demerx, Inc. Method for noribogaine treatment of addiction in patients on methadone
US9561232B2 (en) 2014-02-18 2017-02-07 Demerx, Inc. Low dose noribogaine for treating nicotine addiction and preventing relapse of nicotine use
WO2015126836A2 (en) 2014-02-18 2015-08-27 Demerx, Inc. Therapeutic methods employing noribogaine and related compounds
US9345711B2 (en) 2014-02-18 2016-05-24 Demerx, Inc. Methods for acute and long-term treatment of drug addiction
JP2017509612A (ja) 2014-02-18 2017-04-06 デメルクス,インコーポレイテッド 薬物中毒の急性および長期間での治療方法。
US20150246055A1 (en) 2014-03-03 2015-09-03 Demerx, Inc. Methods for acute and long-term treatment of opioid and opioid-like drug addiction
US20150258114A1 (en) 2014-03-13 2015-09-17 Demerx, Inc. Methods for acute and long-term treatment of substance abuse using ibogaine
US9591978B2 (en) 2014-03-13 2017-03-14 Demerx, Inc. Methods and compositions for pre-screening patients for treatment with noribogaine
US20150258107A1 (en) 2014-03-13 2015-09-17 Demerx, Inc. Methods and compositions for treating depression
US20150258111A1 (en) 2014-03-13 2015-09-17 Demerx, Inc. Methods and compositions for reducing tolerance to opioid analgesics using ibogaine and derivatives thereof
US20150258105A1 (en) 2014-03-13 2015-09-17 Demerx, Inc. Methods for acute and long-term treatment of alcohol dependence
US20150258106A1 (en) 2014-03-13 2015-09-17 Demerx, Inc. Methods for acute and long-term treatment of substance abuse
US20150258108A1 (en) 2014-03-13 2015-09-17 Demerx, Inc. Methods and compositions for reducing tolerance to opioid analgesics
US9561233B2 (en) 2014-03-13 2017-02-07 Demerx, Inc. Use of ibogaine for the treatment of pain
CA2983727A1 (en) 2014-04-21 2015-10-29 Demerx, Inc. N-substituted noribogaine prodrugs
US20150342959A1 (en) 2014-06-03 2015-12-03 Demerx, Inc. Methods and compositions for sustained noribogaine treatment
US9550789B2 (en) 2014-06-18 2017-01-24 Demerx, Inc. Halogenated indole and benzofuran derivatives of isoquinuclidene and processes for preparing them
US9549935B2 (en) 2014-07-14 2017-01-24 Demerx, Inc. Methods and compositions for treating migraines using noribogaine
EP4279134A1 (en) 2014-11-26 2023-11-22 DemeRx, Inc. Methods and compostions for potentiating the action of opioid analgesics using iboga alkaloids
WO2016134019A1 (en) 2015-02-19 2016-08-25 Demerx, Inc. Methods for treating disorders associated with undesired activity of neuronal nicotinic acetylcholine receptors

Also Published As

Publication number Publication date
EA201591679A1 (ru) 2016-05-31
BR112015022465A2 (pt) 2017-07-18
US20150045350A1 (en) 2015-02-12
JP2016514679A (ja) 2016-05-23
ZA201507514B (en) 2018-05-30
AU2014228986A1 (en) 2015-10-29
WO2014144508A2 (en) 2014-09-18
US20140288056A1 (en) 2014-09-25
CA2942511A1 (en) 2014-09-18
EP2968355A4 (en) 2016-08-24
US9744174B2 (en) 2017-08-29
TW201505634A (zh) 2015-02-16
KR20150130461A (ko) 2015-11-23
CN105307658A (zh) 2016-02-03
CA2942638A1 (en) 2014-09-18
EP2968355A2 (en) 2016-01-20
US20160271139A1 (en) 2016-09-22
AR095338A1 (es) 2015-10-07
WO2014143201A1 (en) 2014-09-18

Similar Documents

Publication Publication Date Title
HK1220381A1 (zh) 用於藥物戒斷的非毒性治療方法
IL278018A (en) Methods for the treatment or prevention of ophthalmological conditions
HK1222994A1 (zh) 烟草處理
EP2982390A4 (en) MEDICAL DEVICE AND METHOD FOR PRODUCING A MEDICAL DEVICE
PL2764881T3 (pl) System leczenia medycznego
EP3028722A4 (en) TREATMENT AGENT FOR CARTILAGE DAMAGE AND METHOD FOR THE PRODUCTION THEREOF
EP2957216A4 (en) ENDOSCOPE SYSTEM AND METHOD OF OPERATION FOR ENDOSCOPE SYSTEM
EP2996564C0 (en) MEDICAL DEVICE
SG11201604626VA (en) Medicament apparatus and method
PL3084506T3 (pl) Endoskop i sposób jego użycia
HK1215164A1 (zh) 處理方法
GB201314386D0 (en) Treatment system for aquaculture
HK1214093A1 (zh) 烟草處理
PT3041575T (pt) Aparelho médico
GB201309375D0 (en) Medical methods and compounds for medical use
IL241096A0 (en) Treatment methods
SG11201602010VA (en) Heat treatment method
PT2996460T (pt) Método de tratamento de relvado
PL3041506T3 (pl) Sposób leczenia
GB201322778D0 (en) Method of treatment
GB201318609D0 (en) Medical apparatus and method
GB201314882D0 (en) Method of treatment
GB201309379D0 (en) Medical methods and compounds for medical use
GB201309376D0 (en) Medical methods and compounds for medical use