HK1219428A1 - 具有紫杉醇晶體的多孔複合材料 - Google Patents

具有紫杉醇晶體的多孔複合材料

Info

Publication number
HK1219428A1
HK1219428A1 HK16107522.4A HK16107522A HK1219428A1 HK 1219428 A1 HK1219428 A1 HK 1219428A1 HK 16107522 A HK16107522 A HK 16107522A HK 1219428 A1 HK1219428 A1 HK 1219428A1
Authority
HK
Hong Kong
Prior art keywords
paclitaxel crystals
porous composites
composites
porous
paclitaxel
Prior art date
Application number
HK16107522.4A
Other languages
English (en)
Inventor
Robert L Cleek
Edward H Cully
Paul D Drumheller
Mei Li
Peter D Traylor
Original Assignee
Gore & Ass
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gore & Ass filed Critical Gore & Ass
Publication of HK1219428A1 publication Critical patent/HK1219428A1/zh

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14Macromolecular materials
    • A61L27/16Macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28Materials for coating prostheses
    • A61L27/34Macromolecular materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54Biologically active materials, e.g. therapeutic substances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/56Porous materials, e.g. foams or sponges
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/04Macromolecular materials
    • A61L29/041Macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/08Materials for coatings
    • A61L29/085Macromolecular materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/14Materials characterised by their function or physical properties, e.g. lubricating compositions
    • A61L29/146Porous materials, e.g. foams or sponges
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/14Materials characterised by their function or physical properties, e.g. lubricating compositions
    • A61L29/16Biologically active materials, e.g. therapeutic substances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/14Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/416Anti-neoplastic or anti-proliferative or anti-restenosis or anti-angiogenic agents, e.g. paclitaxel, sirolimus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/63Crystals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00Materials characterised by their function or physical properties
    • A61L2400/18Modification of implant surfaces in order to improve biocompatibility, cell growth, fixation of biomolecules, e.g. plasma treatment

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Materials For Medical Uses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Surgery (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Polymers & Plastics (AREA)
  • Composite Materials (AREA)
  • Materials Engineering (AREA)
HK16107522.4A 2013-03-14 2016-06-28 具有紫杉醇晶體的多孔複合材料 HK1219428A1 (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361786244P 2013-03-14 2013-03-14
US14/210,162 US11167063B2 (en) 2013-03-14 2014-03-13 Porous composites with high-aspect ratio crystals
PCT/US2014/027253 WO2014152360A1 (en) 2013-03-14 2014-03-14 Porous composites with paclitaxel crystals

Publications (1)

Publication Number Publication Date
HK1219428A1 true HK1219428A1 (zh) 2017-04-07

Family

ID=51528026

Family Applications (1)

Application Number Title Priority Date Filing Date
HK16107522.4A HK1219428A1 (zh) 2013-03-14 2016-06-28 具有紫杉醇晶體的多孔複合材料

Country Status (9)

Country Link
US (2) US11167063B2 (zh)
EP (3) EP3542795A1 (zh)
JP (2) JP6273348B2 (zh)
CN (3) CN105188697B (zh)
AU (2) AU2014239905B2 (zh)
CA (2) CA2903278C (zh)
ES (1) ES2744823T3 (zh)
HK (1) HK1219428A1 (zh)
WO (1) WO2014152360A1 (zh)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9872940B2 (en) * 2013-04-01 2018-01-23 Terumo Kabushiki Kaisha Drug coating layer
EP3106197B1 (en) 2014-04-01 2018-09-26 Terumo Kabushiki Kaisha Balloon coating method
CN106132470B (zh) 2014-04-01 2019-09-24 泰尔茂株式会社 用于球囊涂敷的定位方法
CN106163603B (zh) 2014-04-01 2019-11-15 泰尔茂株式会社 用于球囊涂敷的定位方法
JP6866156B2 (ja) * 2014-04-01 2021-04-28 テルモ株式会社 バルーンコーティング方法、コート層制御方法およびバルーンコーティング装置
US10188771B2 (en) * 2014-05-16 2019-01-29 Terumo Kabushiki Kaisha Method of treating peripheral artery diseases in lower limbs
US10149925B2 (en) * 2014-05-16 2018-12-11 Terumo Kabushiki Kaisha Method of reducing the risk of embolization of peripheral blood vessels
US10143779B2 (en) * 2014-05-16 2018-12-04 Terumo Kabushiki Kaisha Method of inhibiting thickening of vascular intima
JP6723807B2 (ja) 2015-04-23 2020-07-15 テルモ株式会社 バルーンコーティング方法、バルーン回転方法およびバルーンコーティング装置
JP6907190B2 (ja) * 2016-03-23 2021-07-21 テルモ株式会社 バルーンカテーテルおよびその製造方法
JP6832339B2 (ja) * 2016-03-23 2021-02-24 テルモ株式会社 バルーンカテーテル及びその製造方法並びに処置方法
JP2017169738A (ja) 2016-03-23 2017-09-28 テルモ株式会社 バルーンカテーテルおよびその製造方法並びに処置方法
JP6472572B2 (ja) * 2016-03-23 2019-02-20 テルモ株式会社 バルーンカテーテルおよびその製造方法並びに処置方法
JP6704273B2 (ja) * 2016-03-23 2020-06-03 テルモ株式会社 バルーンカテーテル及びその製造方法並びに処置方法
JP6668131B2 (ja) * 2016-03-23 2020-03-18 テルモ株式会社 バルーンカテーテルおよびその製造方法並びに処置方法
EP3391932B1 (en) * 2016-03-23 2023-10-11 Terumo Kabushiki Kaisha Balloon catheter and method for producing the same
JP6754423B2 (ja) * 2016-03-23 2020-09-09 テルモ株式会社 バルーンカテーテル及びその製造方法
AU2017280351B2 (en) * 2016-06-24 2020-09-03 W. L. Gore & Associates, Inc. Drug coated balloons and techniques for increasing vascular permeability
CN107362439B (zh) * 2017-08-14 2020-09-01 乐普(北京)医疗器械股份有限公司 一种药物涂层球囊导管的制备方法、制备得到的药物涂层球囊导管及其应用
JP7246311B2 (ja) * 2017-09-21 2023-03-27 テルモ株式会社 薬剤コート層およびその形成方法
EP3643336B1 (en) 2017-09-21 2021-09-01 Terumo Kabushiki Kaisha Method and device for forming drug coating layer
WO2020101675A1 (en) * 2018-11-14 2020-05-22 Lutonix, Inc. Medical device with drug-eluting coating on modified device surface
JP7454666B2 (ja) * 2019-11-12 2024-03-22 ダブリュ.エル.ゴア アンド アソシエイツ,インコーポレイティド 薬物コーティングされたバルーン
CN113041410A (zh) * 2019-12-27 2021-06-29 上海微创医疗器械(集团)有限公司 载药植入医疗器械及其制备方法

Family Cites Families (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5102402A (en) 1991-01-04 1992-04-07 Medtronic, Inc. Releasable coatings on balloon catheters
DE69534230T2 (de) 1994-06-27 2006-01-19 Bard Peripheral Vascular, Inc., Tempe Radial expandierbares polytetrafluorethylen und daraus geformte expandierbare endovaskuläre stents
WO1996003457A1 (en) 1994-07-27 1996-02-08 W.L. Gore & Associates, Inc. High strength porous ptfe sheet material
DE69428056T2 (de) 1994-09-02 2002-01-03 Gore & Ass Poröse polytetrafluorethylen zusammensetzungen
US5814405A (en) 1995-08-04 1998-09-29 W. L. Gore & Associates, Inc. Strong, air permeable membranes of polytetrafluoroethylene
US5824405A (en) 1996-06-07 1998-10-20 W. R. Grace & Co.-Conn. Barrier membrane for protective clothing
US6221153B1 (en) 1998-06-09 2001-04-24 Trevor Percival Castor Method for producing large crystals of complex molecules
US7049380B1 (en) 1999-01-19 2006-05-23 Gore Enterprise Holdings, Inc. Thermoplastic copolymer of tetrafluoroethylene and perfluoromethyl vinyl ether and medical devices employing the copolymer
US6827737B2 (en) 2001-09-25 2004-12-07 Scimed Life Systems, Inc. EPTFE covering for endovascular prostheses and method of manufacture
US6541589B1 (en) 2001-10-15 2003-04-01 Gore Enterprise Holdings, Inc. Tetrafluoroethylene copolymer
EP1451168A4 (en) 2001-11-30 2005-08-24 Bristol Myers Squibb Co PACLITAXELSOLVATE
US20030225439A1 (en) * 2002-05-31 2003-12-04 Cook Alonzo D. Implantable product with improved aqueous interface characteristics and method for making and using same
US20030216803A1 (en) 2003-05-28 2003-11-20 Ledergerber Walter J. Textured and drug eluting stent-grafts
US20060047311A1 (en) 2004-08-26 2006-03-02 Lutz David I Expanded PTFE articles and method of making same
US7329319B2 (en) 2004-11-10 2008-02-12 Illinois Institute Of Technology Method for producing crystals and screening crystallization conditions
US7531611B2 (en) 2005-07-05 2009-05-12 Gore Enterprise Holdings, Inc. Copolymers of tetrafluoroethylene
US7306729B2 (en) 2005-07-18 2007-12-11 Gore Enterprise Holdings, Inc. Porous PTFE materials and articles produced therefrom
US7597924B2 (en) * 2005-08-18 2009-10-06 Boston Scientific Scimed, Inc. Surface modification of ePTFE and implants using the same
JP5118042B2 (ja) * 2005-09-06 2013-01-16 シー・アール・バード・インコーポレーテッド 薬物結晶を含有する移植用インプラント
US8636794B2 (en) * 2005-11-09 2014-01-28 C. R. Bard, Inc. Grafts and stent grafts having a radiopaque marker
US7700716B2 (en) * 2005-12-15 2010-04-20 E. I. Du Pont De Nemours And Company Polytetrafluoroethylene binding peptides and methods of use
US7901726B2 (en) 2007-08-31 2011-03-08 Boston Scientific Scimed, Inc. Porous medical articles for therapeutic agent delivery
US8637144B2 (en) 2007-10-04 2014-01-28 W. L. Gore & Associates, Inc. Expandable TFE copolymers, method of making, and porous, expended articles thereof
EP2271379B1 (en) 2008-03-28 2015-11-25 SurModics, Inc. Insertable medical devices having microparticulate-associated elastic substrates and methods for drug delivery
US8409601B2 (en) 2008-03-31 2013-04-02 Cordis Corporation Rapamycin coated expandable devices
IT1394522B1 (it) * 2009-01-09 2012-07-05 Invatec Technology Ct Gmbh Dispositivo medicale con rilascio di farmaco
US9139669B2 (en) 2009-03-24 2015-09-22 W. L. Gore & Associates, Inc. Expandable functional TFE copolymer fine powder, the expandable functional products obtained therefrom and reaction of the expanded products
WO2010124098A2 (en) 2009-04-24 2010-10-28 Boston Scientific Scimed, Inc. Use of drug polymorphs to achieve controlled drug delivery from a coated medical device
EP2453938B1 (en) * 2009-07-17 2015-08-19 Boston Scientific Scimed, Inc. Nucleation of drug delivery balloons to provide improved crystal size and density
CN102526861A (zh) * 2010-12-27 2012-07-04 微创医疗器械(上海)有限公司 一种介入医疗器械
US10332646B2 (en) * 2011-12-05 2019-06-25 Wisconsin Alumni Research Foundation Apparatus and method for generating medical isotopes
CN102653528B (zh) 2012-04-19 2014-07-16 重庆市碚圣农业科技股份有限公司 用大孔树脂分离纯化紫杉醇与10dabⅲ的方法
CN102727464A (zh) 2012-06-18 2012-10-17 中国科学院化学研究所 自发荧光微胶囊及其制备方法与应用
US9872940B2 (en) 2013-04-01 2018-01-23 Terumo Kabushiki Kaisha Drug coating layer

Also Published As

Publication number Publication date
ES2744823T3 (es) 2020-02-26
EP3542795A1 (en) 2019-09-25
JP6273348B2 (ja) 2018-01-31
CN107007880B (zh) 2020-07-14
WO2014152360A1 (en) 2014-09-25
US11167063B2 (en) 2021-11-09
JP2016513543A (ja) 2016-05-16
EP2968252B1 (en) 2019-06-26
EP2968252A1 (en) 2016-01-20
AU2017222558A1 (en) 2017-09-28
CA2903278A1 (en) 2014-09-25
AU2014239905A1 (en) 2015-09-17
CA3010824C (en) 2020-08-25
JP6496049B2 (ja) 2019-04-03
AU2017222558B2 (en) 2019-04-04
CN105188697A (zh) 2015-12-23
US20140271775A1 (en) 2014-09-18
CN110269956B (zh) 2022-08-02
CN107007880A (zh) 2017-08-04
EP3542794A1 (en) 2019-09-25
CA3010824A1 (en) 2014-09-25
US20220047780A1 (en) 2022-02-17
JP2018089391A (ja) 2018-06-14
CN105188697B (zh) 2019-04-16
CN110269956A (zh) 2019-09-24
AU2014239905B2 (en) 2017-06-08
CA2903278C (en) 2019-04-30

Similar Documents

Publication Publication Date Title
HK1219428A1 (zh) 具有紫杉醇晶體的多孔複合材料
ZA202004893B (en) Materials
IL274355B (en) Aza-pyridone compounds and their uses
IL243747A0 (en) graphene modification
ZA201504446B (en) 81-facet diamond with 10-heart-and-10-arrow structure inside
SG11201601199QA (en) Carbene-functionalized composite materials
GB201300810D0 (en) Composite Materials
GB201323008D0 (en) Compounds and uses thereof
IL240567A0 (en) Polyamide composites containing graphene
GB201303971D0 (en) Absorbent materials
GB201300822D0 (en) Composite materials
HK1213036A1 (zh) 管緊固結構
GB201320674D0 (en) Adsorbent materials
GB201307233D0 (en) Compounds and uses thereof
PL3044389T3 (pl) Konstrukcja słupkowo-ryglowa
GB201300821D0 (en) Composite materials
EP2979746A4 (en) STRUCTURE
GB201309180D0 (en) Compounds and Their Uses
HK1223307A1 (zh) 新型化合物和其用途
GB201314610D0 (en) Compounds and their uses
GB201313495D0 (en) Osteoinductive materials
GB201306248D0 (en) Compounds and their uses
GB2534014B (en) Cache architecture
GB2511577B (en) Carrying structure
GB201312551D0 (en) Composites