HK1214282A1 - 抗-notch3抗体及抗体-药物缀合物 - Google Patents

抗-notch3抗体及抗体-药物缀合物 Download PDF

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Publication number
HK1214282A1
HK1214282A1 HK16102254.9A HK16102254A HK1214282A1 HK 1214282 A1 HK1214282 A1 HK 1214282A1 HK 16102254 A HK16102254 A HK 16102254A HK 1214282 A1 HK1214282 A1 HK 1214282A1
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HK
Hong Kong
Prior art keywords
antibody
seq
notch
notch3
antigen
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HK16102254.9A
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English (en)
Chinese (zh)
Inventor
‧蓋萊斯
K‧G‧盖莱斯
‧高
Y‧高
‧薩普拉
P‧萨普拉
‧奇思蒂亞科娃
L‧G‧奇思蒂亚科娃
‧周
B-B‧S‧周
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辉瑞公司
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Publication of HK1214282A1 publication Critical patent/HK1214282A1/zh

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
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    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3061—Blood cells
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    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
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    • A61K47/6811—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug being a protein or peptide, e.g. transferrin or bleomycin
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