HK1212974A1 - 種高絲氨酸內酯類衍生物、其製備方法和用途 - Google Patents

種高絲氨酸內酯類衍生物、其製備方法和用途

Info

Publication number
HK1212974A1
HK1212974A1 HK16100848.6A HK16100848A HK1212974A1 HK 1212974 A1 HK1212974 A1 HK 1212974A1 HK 16100848 A HK16100848 A HK 16100848A HK 1212974 A1 HK1212974 A1 HK 1212974A1
Authority
HK
Hong Kong
Prior art keywords
derivative
preparation
homoserine lactone
homoserine
lactone
Prior art date
Application number
HK16100848.6A
Other languages
English (en)
Inventor
Song Li
Junhai Xiao
Mingming Zhao
Wu Zhong
Lili Wang
Zhibing Zheng
Yunde Xie
Xingzhou Li
Guoming Zhao
Xinbo Zhou
Xiaokui Wang
Wei Chen
Original Assignee
Inst Of Pharmacology And Toxicology Acad O
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inst Of Pharmacology And Toxicology Acad O filed Critical Inst Of Pharmacology And Toxicology Acad O
Publication of HK1212974A1 publication Critical patent/HK1212974A1/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/32—Oxygen atoms
    • C07D307/33—Oxygen atoms in position 2, the oxygen atom being in its keto or unsubstituted enol form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HK16100848.6A 2013-02-08 2016-01-26 種高絲氨酸內酯類衍生物、其製備方法和用途 HK1212974A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN201310049962.1A CN103980233B (zh) 2013-02-08 2013-02-08 一种高丝氨酸内酯类衍生物、其制备方法和用途
PCT/CN2013/088932 WO2014121633A1 (zh) 2013-02-08 2013-12-10 一种高丝氨酸内酯类衍生物、其制备方法和用途

Publications (1)

Publication Number Publication Date
HK1212974A1 true HK1212974A1 (zh) 2016-06-24

Family

ID=51272429

Family Applications (1)

Application Number Title Priority Date Filing Date
HK16100848.6A HK1212974A1 (zh) 2013-02-08 2016-01-26 種高絲氨酸內酯類衍生物、其製備方法和用途

Country Status (6)

Country Link
US (1) US9630939B2 (zh)
EP (1) EP2955174B1 (zh)
JP (1) JP6301369B2 (zh)
CN (1) CN103980233B (zh)
HK (1) HK1212974A1 (zh)
WO (1) WO2014121633A1 (zh)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105130970B (zh) * 2014-05-30 2019-06-25 中国人民解放军军事医学科学院毒物药物研究所 N-磺酰基高丝氨酸内酯类衍生物、其制备方法和用途
CN104356099B (zh) * 2014-11-19 2016-05-11 郑州大学 高丝氨酸内酯类化合物、其制备方法及其应用
CN106146432B (zh) * 2015-03-23 2018-12-21 兰州大学 一种酰化高丝氨酸内酯类化合物及其环保应用
CN110003148B (zh) * 2019-04-29 2023-03-24 安徽安力肽生物科技有限公司 一种高丝氨酸内酯盐酸盐的制备方法
CN115038688A (zh) * 2019-09-11 2022-09-09 文森雷生物科学股份有限公司 Usp30抑制剂及其用途
CN112624997A (zh) * 2019-09-24 2021-04-09 中国人民解放军军事科学院军事医学研究院 一种3-氨基-2-噁唑烷酮类衍生物的制备方法和用途

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0610042D0 (en) * 2006-05-22 2006-06-28 Univ Nottingham Substituted n-acyl homoserine lactones
KR100841333B1 (ko) 2006-11-22 2008-06-25 재단법인서울대학교산학협력재단 항균성 호모세린 락톤 유도체 및 이를 이용한 미생물의제거 방법
US7910622B2 (en) 2007-03-19 2011-03-22 Wisconsin Alumni Research Foundation Modulation of bacterial quorum sensing with synthetic ligands

Also Published As

Publication number Publication date
WO2014121633A1 (zh) 2014-08-14
EP2955174A4 (en) 2016-09-28
CN103980233A (zh) 2014-08-13
US20150368217A1 (en) 2015-12-24
JP2016509004A (ja) 2016-03-24
EP2955174A1 (en) 2015-12-16
JP6301369B2 (ja) 2018-03-28
CN103980233B (zh) 2017-07-04
US9630939B2 (en) 2017-04-25
EP2955174B1 (en) 2019-02-27

Similar Documents

Publication Publication Date Title
HK1221720A1 (zh) 喹唑啉衍生物及其製備方法
ZA201603889B (en) N-benzyl tryptanthrin derivative, and preparation method and application thereof
GB2535360B (en) Methods of preparing polyhemiaminals and polyhexahydrotriazines
HK1217708A1 (zh) 新的雷公藤甲素衍生物及其製備方法和用途
PL3061747T3 (pl) Pochodne ketonów pirydynowych, sposób ich wytwarzania i ich zastosowanie farmaceutyczne
HK1209324A1 (zh) 納米酶、製備納米酶的方法、以及使用納米酶的方法
IL269622A (en) Preparation of (s,s)-secoisolariciresinol diglucoside and (r,r)- secoisolariciresinol diglucoside
HK1212974A1 (zh) 種高絲氨酸內酯類衍生物、其製備方法和用途
EP3000133A4 (en) SENSORS, METHOD OF MANUFACTURING AND DEVICES
SI3064498T1 (sl) Derivati pirazolopirimidona ali pirolotriazona, postopki priprave le-teh in farmacevtske uporabe le-teh
ZA201602198B (en) Preparation of hydroxy-benzylbenzene derivatives
HK1225993A1 (zh) 糖胺聚糖的化合物、其製備方法及用途
ZA201602831B (en) Use of lactones
HRP20180877T1 (hr) Derivati tilozina i postupci njihove priprave
HK1206329A1 (zh) 苯酚衍生物及其製備方法和在醫藥上的應用
EP2952519A4 (en) PROTOPANOXADIOL DERIVATIVE, PREPARATION METHOD AND APPLICATION THEREOF
EP3078659A4 (en) 3-FURYL-2-CYANO-2-ACRYLAMIDE DERIVATIVE, PROCESS FOR PREPARING THE SAME, PHARMACEUTICAL COMPOSITION AND USE THEREOF
PT3010896T (pt) Derivados inovadores de amidino-ureia macrocíclicos, métodos de preparação e utilizações dos mesmos como inibidores de quitinase
ZA201603990B (en) Taxane compound, and preparation method and use thereof
ZA201603682B (en) Taxanes compounds, preparation method therefor, and uses thereof
HK1244814A1 (zh) 一種薯蕷皂苷元-3-位衍生物及其製備方法和用途
HUE041663T2 (hu) Myxopyronin és származékai elõállítása
EP2970175A4 (en) CELLULAR ADDUCTS, METHODS OF MAKING SAME, AND USES THEREOF
GB201301690D0 (en) Hollow component and method of manufacture