HK1211587A1 - Process for purifying staurosporine - Google Patents
Process for purifying staurosporineInfo
- Publication number
- HK1211587A1 HK1211587A1 HK15112508.3A HK15112508A HK1211587A1 HK 1211587 A1 HK1211587 A1 HK 1211587A1 HK 15112508 A HK15112508 A HK 15112508A HK 1211587 A1 HK1211587 A1 HK 1211587A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- staurosporine
- purifying
- purifying staurosporine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/22—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains four or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/351—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom not condensed with another ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/553—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one oxygen as ring hetero atoms, e.g. loxapine, staurosporine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
- Extraction Or Liquid Replacement (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US62534304P | 2004-11-05 | 2004-11-05 | |
US64213105P | 2005-01-07 | 2005-01-07 |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1211587A1 true HK1211587A1 (en) | 2016-05-27 |
Family
ID=35501294
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK07113889.0A HK1108881A1 (en) | 2004-11-05 | 2007-12-19 | Organic compounds |
HK15112508.3A HK1211587A1 (en) | 2004-11-05 | 2007-12-19 | Process for purifying staurosporine |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK07113889.0A HK1108881A1 (en) | 2004-11-05 | 2007-12-19 | Organic compounds |
Country Status (31)
Country | Link |
---|---|
US (2) | US8198435B2 (hr) |
EP (3) | EP2955186A1 (hr) |
JP (4) | JP5057986B2 (hr) |
KR (3) | KR101265850B1 (hr) |
CN (2) | CN102627658A (hr) |
AR (1) | AR052322A1 (hr) |
AU (2) | AU2005300693B2 (hr) |
BR (1) | BRPI0517689A (hr) |
CA (1) | CA2584911C (hr) |
CY (1) | CY1113059T1 (hr) |
DK (1) | DK1812448T3 (hr) |
EC (1) | ECSP12007431A (hr) |
ES (1) | ES2388142T3 (hr) |
GT (1) | GT200500311A (hr) |
HK (2) | HK1108881A1 (hr) |
HR (1) | HRP20120652T1 (hr) |
IL (3) | IL182691A (hr) |
JO (1) | JO2897B1 (hr) |
MA (1) | MA29033B1 (hr) |
MX (2) | MX2007005429A (hr) |
MY (2) | MY154878A (hr) |
NO (2) | NO338960B1 (hr) |
NZ (3) | NZ554653A (hr) |
PE (3) | PE20130377A1 (hr) |
PL (1) | PL1812448T3 (hr) |
PT (1) | PT1812448E (hr) |
RU (2) | RU2394038C2 (hr) |
SI (1) | SI1812448T1 (hr) |
TN (1) | TNSN07165A1 (hr) |
TW (4) | TWI530500B (hr) |
WO (1) | WO2006048296A1 (hr) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE602007013567D1 (de) | 2006-08-16 | 2011-05-12 | Novartis Ag | Verfahren zur herstellung fester dispersionen von midostaurin |
EP2327706A1 (en) * | 2009-11-30 | 2011-06-01 | Novartis AG | Polymorphous forms III and IV of N-benzoyl-staurosporine |
KR20160008267A (ko) | 2014-07-14 | 2016-01-22 | 주식회사 윈스 | 네트워크 기반 영상감시체계에서의 사용자 행위 분석 시스템 |
EP3592749A1 (en) * | 2017-03-06 | 2020-01-15 | Teva Pharmaceutical Works Ltd. | Solid state forms of midostaurin |
WO2019215759A1 (en) * | 2018-05-09 | 2019-11-14 | Alaparthi Lakshmi Prasad | An improved process for preparation of midostaurin |
IT201900004729A1 (it) | 2019-03-29 | 2020-09-29 | Procos Spa | Processo per la preparazione di midostaurina ad elevato grado di purezza |
US20220242880A1 (en) * | 2019-06-24 | 2022-08-04 | Dr. Reddy?s Laboratories Limited | Process for preparation of midostaurin |
IT201900014346A1 (it) | 2019-08-08 | 2021-02-08 | Procos Spa | Processo per la preparazione di midostaurina amorfa con un basso contenuto di solvente organico residuo |
IT202000004291A1 (it) | 2020-03-02 | 2021-09-02 | Indena Spa | Processo per la purificazione di alcaloidi indolo carbazolici |
CN111393454A (zh) * | 2020-05-07 | 2020-07-10 | 奥锐特药业(天津)有限公司 | 米哚妥林的新晶型及其制备方法 |
CN115124551B (zh) * | 2021-03-24 | 2024-04-30 | 奥锐特药业(天津)有限公司 | 一种高纯度米哚妥林的制备方法 |
WO2023205504A1 (en) * | 2022-04-22 | 2023-10-26 | Rutgers, The State University Of New Jersey | Formulations and methods for treating epidermolysis bullosa simplex and related conditions |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5373501A (en) * | 1976-12-11 | 1978-06-30 | Kitasato Inst | Novel antibiotics amm2282 and process for preparing same |
JPS60185719A (ja) | 1984-03-06 | 1985-09-21 | Ajinomoto Co Inc | 抗腫瘍剤 |
IL86632A0 (en) * | 1987-06-15 | 1988-11-30 | Ciba Geigy Ag | Derivatives substituted at methyl-amino nitrogen |
US5093330A (en) | 1987-06-15 | 1992-03-03 | Ciba-Geigy Corporation | Staurosporine derivatives substituted at methylamino nitrogen |
US5073633A (en) * | 1989-03-23 | 1991-12-17 | Bristol-Myers Company | BMY-41950 antitumor antibiotic |
US5096330A (en) * | 1990-06-21 | 1992-03-17 | M-B-W Inc. | Pitch control mechanism for a surface finishing machine |
JPH05247055A (ja) * | 1992-03-03 | 1993-09-24 | Meiji Seika Kaisha Ltd | スタウロスポリン誘導体及びそれを含有する抗腫瘍効果増強剤 |
JPH05247955A (ja) | 1992-03-06 | 1993-09-24 | Taisei Corp | 擁壁の施工方法 |
EP0575955B1 (en) | 1992-06-22 | 1999-09-15 | Kyowa Hakko Kogyo Co., Ltd. | Process for producing staurosporine derivatives |
JPH10501527A (ja) * | 1994-06-01 | 1998-02-10 | チバ−ガイギー アクチェンゲゼルシャフト | 多重薬剤耐性細胞を抗腫瘍剤に対して感受性にするためのインドロカルバゾール誘導体 |
RU2191175C2 (ru) | 1995-12-11 | 2002-10-20 | Сефалон, Инкорпорейтед | Конденсированные изоиндолоны в качестве ингибиторов протеинкиназы с |
CN1367789B (zh) * | 1999-08-30 | 2012-06-06 | 波利弗尔股份公司 | 模板固定的β-发夹环模拟物的合成 |
CA2439097C (en) | 2001-03-26 | 2010-10-12 | Novartis Ag | Pharmaceutical compositions |
KR100407758B1 (ko) | 2001-08-27 | 2003-12-01 | 씨제이 주식회사 | 스타틴의 제조에 있어서 락톤화 방법 |
WO2004094645A1 (en) * | 2003-04-22 | 2004-11-04 | Lonza Ag | Process for the recovery of staurosporine from a fermentation broth |
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2005
- 2005-10-26 JO JO2005162A patent/JO2897B1/en active
- 2005-10-28 GT GT200500311A patent/GT200500311A/es unknown
- 2005-10-28 MY MYPI20091911A patent/MY154878A/en unknown
- 2005-10-28 MY MYPI20055091A patent/MY147404A/en unknown
- 2005-11-03 MX MX2007005429A patent/MX2007005429A/es active IP Right Grant
- 2005-11-03 KR KR1020127022582A patent/KR101265850B1/ko active IP Right Grant
- 2005-11-03 CN CN2012101018747A patent/CN102627658A/zh active Pending
- 2005-11-03 BR BRPI0517689-1A patent/BRPI0517689A/pt not_active IP Right Cessation
- 2005-11-03 NZ NZ554653A patent/NZ554653A/en not_active IP Right Cessation
- 2005-11-03 NZ NZ588025A patent/NZ588025A/en not_active IP Right Cessation
- 2005-11-03 JP JP2007539535A patent/JP5057986B2/ja active Active
- 2005-11-03 KR KR1020127022584A patent/KR101289998B1/ko active IP Right Grant
- 2005-11-03 ES ES05803350T patent/ES2388142T3/es active Active
- 2005-11-03 US US11/718,029 patent/US8198435B2/en active Active
- 2005-11-03 NZ NZ599033A patent/NZ599033A/xx not_active IP Right Cessation
- 2005-11-03 WO PCT/EP2005/011789 patent/WO2006048296A1/en active Application Filing
- 2005-11-03 CN CN2012104320940A patent/CN102993213A/zh active Pending
- 2005-11-03 KR KR1020077010191A patent/KR101333851B1/ko active IP Right Grant
- 2005-11-03 PT PT05803350T patent/PT1812448E/pt unknown
- 2005-11-03 DK DK05803350.7T patent/DK1812448T3/da active
- 2005-11-03 PL PL05803350T patent/PL1812448T3/pl unknown
- 2005-11-03 CA CA2584911A patent/CA2584911C/en active Active
- 2005-11-03 EP EP15171908.5A patent/EP2955186A1/en not_active Withdrawn
- 2005-11-03 MX MX2011007303A patent/MX346525B/es unknown
- 2005-11-03 SI SI200531555T patent/SI1812448T1/sl unknown
- 2005-11-03 AU AU2005300693A patent/AU2005300693B2/en active Active
- 2005-11-03 RU RU2007120695/04A patent/RU2394038C2/ru active
- 2005-11-03 EP EP05803350A patent/EP1812448B1/en active Active
- 2005-11-03 EP EP10173464.8A patent/EP2272850B1/en active Active
- 2005-11-04 TW TW101122880A patent/TWI530500B/zh not_active IP Right Cessation
- 2005-11-04 TW TW101122882A patent/TWI455941B/zh not_active IP Right Cessation
- 2005-11-04 TW TW094138677A patent/TWI433852B/zh not_active IP Right Cessation
- 2005-11-04 PE PE2012002519A patent/PE20130377A1/es not_active Application Discontinuation
- 2005-11-04 PE PE2005001297A patent/PE20060947A1/es not_active Application Discontinuation
- 2005-11-04 PE PE2009000199A patent/PE20090433A1/es not_active Application Discontinuation
- 2005-11-04 AR ARP050104637A patent/AR052322A1/es not_active Application Discontinuation
- 2005-11-04 TW TW103130302A patent/TWI530501B/zh not_active IP Right Cessation
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2007
- 2007-04-19 IL IL182691A patent/IL182691A/en active IP Right Grant
- 2007-05-02 NO NO20072290A patent/NO338960B1/no unknown
- 2007-05-04 TN TNP2007000165A patent/TNSN07165A1/fr unknown
- 2007-05-22 MA MA29924A patent/MA29033B1/fr unknown
- 2007-12-19 HK HK07113889.0A patent/HK1108881A1/xx unknown
- 2007-12-19 HK HK15112508.3A patent/HK1211587A1/xx unknown
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2009
- 2009-10-13 RU RU2009137788/04A patent/RU2467012C2/ru active
- 2009-12-07 AU AU2009245817A patent/AU2009245817B2/en active Active
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2010
- 2010-08-19 IL IL207702A patent/IL207702A/en active IP Right Grant
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2012
- 2012-01-16 IL IL217571A patent/IL217571A/en active IP Right Grant
- 2012-03-12 EC ECSP12007431 patent/ECSP12007431A/es unknown
- 2012-05-11 JP JP2012109447A patent/JP5701246B2/ja active Active
- 2012-05-15 US US13/472,130 patent/US8710216B2/en active Active
- 2012-08-10 HR HRP20120652TT patent/HRP20120652T1/hr unknown
- 2012-08-21 CY CY20121100747T patent/CY1113059T1/el unknown
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2015
- 2015-01-09 JP JP2015003634A patent/JP2015063569A/ja not_active Withdrawn
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2016
- 2016-07-12 NO NO20161152A patent/NO340404B1/no unknown
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2017
- 2017-01-13 JP JP2017004320A patent/JP2017061578A/ja active Pending
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