HK1211025A1 - 吲哚啉类 - Google Patents

吲哚啉类 Download PDF

Info

Publication number
HK1211025A1
HK1211025A1 HK15111756.4A HK15111756A HK1211025A1 HK 1211025 A1 HK1211025 A1 HK 1211025A1 HK 15111756 A HK15111756 A HK 15111756A HK 1211025 A1 HK1211025 A1 HK 1211025A1
Authority
HK
Hong Kong
Prior art keywords
pharmaceutically acceptable
acceptable salt
phenyl
alkyl
methyl
Prior art date
Application number
HK15111756.4A
Other languages
English (en)
Chinese (zh)
Inventor
Joan Heather Hogg
Stacy Remiszewski
Weiya Yun
Original Assignee
霍夫曼-拉罗奇有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 霍夫曼-拉罗奇有限公司 filed Critical 霍夫曼-拉罗奇有限公司
Publication of HK1211025A1 publication Critical patent/HK1211025A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/30Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/42Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Epidemiology (AREA)
  • Indole Compounds (AREA)
HK15111756.4A 2012-10-11 2013-10-01 吲哚啉类 HK1211025A1 (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261712317P 2012-10-11 2012-10-11
US61/712,317 2012-10-11
PCT/EP2013/070407 WO2014056755A1 (en) 2012-10-11 2013-10-01 Indolines

Publications (1)

Publication Number Publication Date
HK1211025A1 true HK1211025A1 (zh) 2016-05-13

Family

ID=49293651

Family Applications (1)

Application Number Title Priority Date Filing Date
HK15111756.4A HK1211025A1 (zh) 2012-10-11 2013-10-01 吲哚啉类

Country Status (10)

Country Link
US (1) US9403768B2 (https=)
EP (1) EP2906535B1 (https=)
JP (1) JP6333825B2 (https=)
KR (1) KR20150065718A (https=)
CN (1) CN104736519B (https=)
CA (1) CA2884708A1 (https=)
HK (1) HK1211025A1 (https=)
MX (1) MX2015004465A (https=)
RU (1) RU2015113959A (https=)
WO (1) WO2014056755A1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10383538B2 (en) 2014-09-29 2019-08-20 New York Institute Of Technology Catheter for use in recording his electrogram alternans and application to various conditions
WO2016079527A1 (en) 2014-11-19 2016-05-26 Tetralogic Birinapant Uk Ltd Combination therapy
WO2016097773A1 (en) 2014-12-19 2016-06-23 Children's Cancer Institute Therapeutic iap antagonists for treating proliferative disorders
CN118436801A (zh) 2016-05-20 2024-08-06 豪夫迈·罗氏有限公司 Protac抗体缀合物及其使用方法
WO2021026349A1 (en) 2019-08-08 2021-02-11 Institute For Cancer Research D/B/A The Research Institute Of Fox Chase Cancer Center Combination therapy for treatment of cancer
WO2023056069A1 (en) 2021-09-30 2023-04-06 Angiex, Inc. Degrader-antibody conjugates and methods of using same

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2733995B1 (fr) 1995-05-09 1997-07-25 Inst Nat Sante Rech Med Inhibiteurs de l'inactivation de neuropeptides endogenes notamment la cholecystokinine, leurs procedes de preparation leur utilisation comme medicaments et procede de criblage de medicaments
EP1715882A4 (en) * 2004-01-16 2009-04-08 Univ Michigan SMAC-PEPTIDOMIMETIKA AND ITS USES
CN101094833A (zh) * 2004-07-12 2007-12-26 伊邓药品公司 四肽类似物
CA2573644A1 (en) 2004-07-12 2006-02-16 Idun Pharmaceuticals, Inc. Tetrapeptide analogs
JP2011529962A (ja) * 2008-08-02 2011-12-15 ジェネンテック, インコーポレイテッド Iapのインヒビター

Also Published As

Publication number Publication date
WO2014056755A1 (en) 2014-04-17
KR20150065718A (ko) 2015-06-15
JP6333825B2 (ja) 2018-05-30
EP2906535B1 (en) 2018-08-08
CN104736519A (zh) 2015-06-24
US9403768B2 (en) 2016-08-02
CA2884708A1 (en) 2014-04-17
CN104736519B (zh) 2018-12-04
RU2015113959A (ru) 2016-12-10
US20150246882A1 (en) 2015-09-03
EP2906535A1 (en) 2015-08-19
JP2015534567A (ja) 2015-12-03
MX2015004465A (es) 2015-07-14

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