CA2884708A1 - Indolines - Google Patents
Indolines Download PDFInfo
- Publication number
- CA2884708A1 CA2884708A1 CA2884708A CA2884708A CA2884708A1 CA 2884708 A1 CA2884708 A1 CA 2884708A1 CA 2884708 A CA2884708 A CA 2884708A CA 2884708 A CA2884708 A CA 2884708A CA 2884708 A1 CA2884708 A1 CA 2884708A1
- Authority
- CA
- Canada
- Prior art keywords
- pharmaceutically acceptable
- acceptable salt
- alkyl
- phenyl
- methyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Epidemiology (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261712317P | 2012-10-11 | 2012-10-11 | |
| US61/712,317 | 2012-10-11 | ||
| PCT/EP2013/070407 WO2014056755A1 (en) | 2012-10-11 | 2013-10-01 | Indolines |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2884708A1 true CA2884708A1 (en) | 2014-04-17 |
Family
ID=49293651
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2884708A Abandoned CA2884708A1 (en) | 2012-10-11 | 2013-10-01 | Indolines |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US9403768B2 (https=) |
| EP (1) | EP2906535B1 (https=) |
| JP (1) | JP6333825B2 (https=) |
| KR (1) | KR20150065718A (https=) |
| CN (1) | CN104736519B (https=) |
| CA (1) | CA2884708A1 (https=) |
| HK (1) | HK1211025A1 (https=) |
| MX (1) | MX2015004465A (https=) |
| RU (1) | RU2015113959A (https=) |
| WO (1) | WO2014056755A1 (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10383538B2 (en) | 2014-09-29 | 2019-08-20 | New York Institute Of Technology | Catheter for use in recording his electrogram alternans and application to various conditions |
| WO2016079527A1 (en) | 2014-11-19 | 2016-05-26 | Tetralogic Birinapant Uk Ltd | Combination therapy |
| WO2016097773A1 (en) | 2014-12-19 | 2016-06-23 | Children's Cancer Institute | Therapeutic iap antagonists for treating proliferative disorders |
| CN118436801A (zh) | 2016-05-20 | 2024-08-06 | 豪夫迈·罗氏有限公司 | Protac抗体缀合物及其使用方法 |
| WO2021026349A1 (en) | 2019-08-08 | 2021-02-11 | Institute For Cancer Research D/B/A The Research Institute Of Fox Chase Cancer Center | Combination therapy for treatment of cancer |
| WO2023056069A1 (en) | 2021-09-30 | 2023-04-06 | Angiex, Inc. | Degrader-antibody conjugates and methods of using same |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2733995B1 (fr) | 1995-05-09 | 1997-07-25 | Inst Nat Sante Rech Med | Inhibiteurs de l'inactivation de neuropeptides endogenes notamment la cholecystokinine, leurs procedes de preparation leur utilisation comme medicaments et procede de criblage de medicaments |
| EP1715882A4 (en) * | 2004-01-16 | 2009-04-08 | Univ Michigan | SMAC-PEPTIDOMIMETIKA AND ITS USES |
| CN101094833A (zh) * | 2004-07-12 | 2007-12-26 | 伊邓药品公司 | 四肽类似物 |
| CA2573644A1 (en) | 2004-07-12 | 2006-02-16 | Idun Pharmaceuticals, Inc. | Tetrapeptide analogs |
| JP2011529962A (ja) * | 2008-08-02 | 2011-12-15 | ジェネンテック， インコーポレイテッド | Ｉａｐのインヒビター |
-
2013
- 2013-10-01 CA CA2884708A patent/CA2884708A1/en not_active Abandoned
- 2013-10-01 US US14/432,990 patent/US9403768B2/en not_active Expired - Fee Related
- 2013-10-01 JP JP2015536065A patent/JP6333825B2/ja not_active Expired - Fee Related
- 2013-10-01 EP EP13771145.3A patent/EP2906535B1/en not_active Not-in-force
- 2013-10-01 CN CN201380052826.6A patent/CN104736519B/zh not_active Expired - Fee Related
- 2013-10-01 RU RU2015113959A patent/RU2015113959A/ru not_active Application Discontinuation
- 2013-10-01 HK HK15111756.4A patent/HK1211025A1/xx unknown
- 2013-10-01 KR KR1020157009107A patent/KR20150065718A/ko not_active Withdrawn
- 2013-10-01 MX MX2015004465A patent/MX2015004465A/es unknown
- 2013-10-01 WO PCT/EP2013/070407 patent/WO2014056755A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| WO2014056755A1 (en) | 2014-04-17 |
| KR20150065718A (ko) | 2015-06-15 |
| JP6333825B2 (ja) | 2018-05-30 |
| EP2906535B1 (en) | 2018-08-08 |
| CN104736519A (zh) | 2015-06-24 |
| US9403768B2 (en) | 2016-08-02 |
| CN104736519B (zh) | 2018-12-04 |
| RU2015113959A (ru) | 2016-12-10 |
| US20150246882A1 (en) | 2015-09-03 |
| HK1211025A1 (zh) | 2016-05-13 |
| EP2906535A1 (en) | 2015-08-19 |
| JP2015534567A (ja) | 2015-12-03 |
| MX2015004465A (es) | 2015-07-14 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EP2931719B1 (en) | Dimeric compounds | |
| EP2897972B1 (en) | 2-oxo-2,3,4,5-tetrahydro-1h-benzo[b]diazepines and their use in the treatment of cancer | |
| EP2906535B1 (en) | Indolines | |
| JP6333267B2 (ja) | アザインドリン | |
| JP6203261B2 (ja) | Ｂｉｒ２及び／又はｂｉｒ３阻害剤としての含窒素複素環式化合物 | |
| US9309248B2 (en) | Azaindolines | |
| HK1206718B (en) | Azaindolines |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Dead |
Effective date: 20181002 |