HK1210497A1 - Cell line expressing single chain factor viii polypeptides and uses thereof viii - Google Patents

Cell line expressing single chain factor viii polypeptides and uses thereof viii

Info

Publication number
HK1210497A1
HK1210497A1 HK15111207.9A HK15111207A HK1210497A1 HK 1210497 A1 HK1210497 A1 HK 1210497A1 HK 15111207 A HK15111207 A HK 15111207A HK 1210497 A1 HK1210497 A1 HK 1210497A1
Authority
HK
Hong Kong
Prior art keywords
viii
cell line
single chain
line expressing
chain factor
Prior art date
Application number
HK15111207.9A
Other languages
English (en)
Chinese (zh)
Inventor
Susan Low
Jennifer A Dumont
Alan J Bitonti
Original Assignee
Biogen Idec Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=49882632&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1210497(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Biogen Idec Inc filed Critical Biogen Idec Inc
Publication of HK1210497A1 publication Critical patent/HK1210497A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/31—Fusion polypeptide fusions, other than Fc, for prolonged plasma life, e.g. albumin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
HK15111207.9A 2012-07-06 2015-11-13 Cell line expressing single chain factor viii polypeptides and uses thereof viii HK1210497A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261668889P 2012-07-06 2012-07-06
PCT/US2013/049460 WO2014008480A2 (en) 2012-07-06 2013-07-05 Cell line expressing single chain factor viii polypeptides and uses thereof

Publications (1)

Publication Number Publication Date
HK1210497A1 true HK1210497A1 (en) 2016-04-22

Family

ID=49882632

Family Applications (1)

Application Number Title Priority Date Filing Date
HK15111207.9A HK1210497A1 (en) 2012-07-06 2015-11-13 Cell line expressing single chain factor viii polypeptides and uses thereof viii

Country Status (4)

Country Link
US (2) US10023628B2 (de)
EP (2) EP2870250B2 (de)
HK (1) HK1210497A1 (de)
WO (1) WO2014008480A2 (de)

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EP2870250B2 (de) 2012-07-06 2022-06-29 Bioverativ Therapeutics Inc. Einkettige faktor-viii-polypeptide exprimierende zelllinie und verwendungen davon
WO2014018777A2 (en) 2012-07-25 2014-01-30 Biogen Idec Ma Inc. Blood factor monitoring assay and uses thereof
WO2016025764A2 (en) * 2014-08-13 2016-02-18 The Children's Hospital Of Philadelphia An improved expression cassette for packaging and expression of variant factor viii for the treatment of hemostasis disorders
WO2017023904A2 (en) * 2015-08-04 2017-02-09 The Scripps Research Institute Nicotine-degrading enzymes for treating nicotine addiction and nicotine poisoning
US20190144524A1 (en) * 2016-01-14 2019-05-16 The Children's Hospital Of Philadelphia Factor viii variants, nucleic acid sequences, and methods and uses for treatment of hemostasis disorders
WO2017222330A1 (ko) * 2016-06-24 2017-12-28 재단법인 목암생명과학연구소 재조합 단쇄 fviii 및 그 화학 접합물
CN106279437B (zh) * 2016-08-19 2017-10-31 安源医药科技（上海）有限公司 高糖基化人凝血因子viii融合蛋白及其制备方法与用途
CN107759696A (zh) 2016-08-19 2018-03-06 安源医药科技（上海）有限公司 人白介素7融合蛋白及其制备方法
WO2019067766A1 (en) 2017-09-27 2019-04-04 Sigilon Therapeutics, Inc. METHODS, COMPOSITIONS AND IMPLANTABLE ELEMENTS COMPRISING ACTIVE CELLS
KR101952102B1 (ko) * 2017-12-07 2019-02-26 주식회사 지앤피바이오사이언스 단백질 발현량이 증대된 인자 ⅷ 변이체 발현벡터
UY38160A (es) 2018-04-04 2019-11-29 Sigilon Therapeutics Inc Partículas implantables y métodos relacionados
US20210145889A1 (en) 2018-04-04 2021-05-20 Sigilon Therapeutics, Inc. Methods, compositions, and implantable elements comprising stem cells
CN113039200B (zh) * 2018-05-18 2023-07-25 郑州晟斯生物科技有限公司 改进的fviii融合蛋白及其应用
UY38389A (es) 2018-09-27 2020-04-30 Sigilon Therapeutics Inc Dispositivos implantables para terapia celular y métodos relacionados
EP3736286A1 (de) 2019-05-09 2020-11-11 Biotest AG Einzelkettenfaktor-viii-molekül
CN110628816B (zh) * 2019-09-12 2022-10-18 中国医学科学院血液病医院(中国医学科学院血液学研究所) 一种用于血友病a的双切供体及其药物组合
WO2024081310A1 (en) 2022-10-11 2024-04-18 Sigilon Therapeutics, Inc. Engineered cells and implantable elements for treatment of disease
WO2024081309A1 (en) 2022-10-11 2024-04-18 Sigilon Therapeutics, Inc. Engineered cells and implantable elements for treatment of disease

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Also Published As

Publication number Publication date
WO2014008480A2 (en) 2014-01-09
WO2014008480A3 (en) 2014-04-10
US20190010212A1 (en) 2019-01-10
EP2870250B2 (de) 2022-06-29
EP2870250A2 (de) 2015-05-13
US20150191526A1 (en) 2015-07-09
EP2870250A4 (de) 2016-02-10
EP3404105A1 (de) 2018-11-21
EP2870250B1 (de) 2018-04-18
US10023628B2 (en) 2018-07-17

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