HK1210031A1 - Therapeutic agent or prophylactic agent for dementia - Google Patents

Therapeutic agent or prophylactic agent for dementia

Info

Publication number
HK1210031A1
HK1210031A1 HK15110820.8A HK15110820A HK1210031A1 HK 1210031 A1 HK1210031 A1 HK 1210031A1 HK 15110820 A HK15110820 A HK 15110820A HK 1210031 A1 HK1210031 A1 HK 1210031A1
Authority
HK
Hong Kong
Prior art keywords
agent
dementia
prophylactic
therapeutic agent
therapeutic
Prior art date
Application number
HK15110820.8A
Other languages
English (en)
Chinese (zh)
Inventor
森启
富山貴美
松本洋
江口廣志
九里裕
Original Assignee
Univ Osaka City
Teijin Pharma Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Osaka City, Teijin Pharma Ltd filed Critical Univ Osaka City
Publication of HK1210031A1 publication Critical patent/HK1210031A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4711Alzheimer's disease; Amyloid plaque core protein
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)
HK15110820.8A 2012-05-31 2015-11-03 Therapeutic agent or prophylactic agent for dementia HK1210031A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2012124336 2012-05-31
PCT/JP2013/065090 WO2013180238A1 (fr) 2012-05-31 2013-05-30 Agent thérapeutique ou agent prophylactique pour la démence

Publications (1)

Publication Number Publication Date
HK1210031A1 true HK1210031A1 (en) 2016-04-15

Family

ID=49673425

Family Applications (1)

Application Number Title Priority Date Filing Date
HK15110820.8A HK1210031A1 (en) 2012-05-31 2015-11-03 Therapeutic agent or prophylactic agent for dementia

Country Status (31)

Country Link
US (3) US20150183854A1 (fr)
EP (2) EP3662931B1 (fr)
JP (3) JP5971659B2 (fr)
KR (2) KR102208283B1 (fr)
CN (1) CN104602708B (fr)
AR (1) AR091218A1 (fr)
AU (2) AU2013268364B2 (fr)
BR (1) BR112014029566A2 (fr)
CA (1) CA2875205C (fr)
CY (1) CY1122530T1 (fr)
DK (1) DK2857039T3 (fr)
ES (2) ES2763361T3 (fr)
HK (1) HK1210031A1 (fr)
HR (1) HRP20192267T1 (fr)
HU (1) HUE046919T2 (fr)
IL (1) IL235899B (fr)
LT (1) LT2857039T (fr)
ME (1) ME03587B (fr)
MX (1) MX361128B (fr)
MY (1) MY172458A (fr)
NZ (1) NZ630536A (fr)
PH (1) PH12014502669A1 (fr)
PL (1) PL2857039T3 (fr)
PT (1) PT2857039T (fr)
RS (1) RS59802B1 (fr)
RU (1) RU2657438C2 (fr)
SG (2) SG10201805410XA (fr)
SI (1) SI2857039T1 (fr)
TW (2) TWI777183B (fr)
WO (1) WO2013180238A1 (fr)
ZA (1) ZA201409186B (fr)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8703137B2 (en) 2011-01-31 2014-04-22 Intellect Neurosciences Inc. Treatment of tauopathies
EP2709728B1 (fr) * 2011-05-20 2019-01-23 Oligomerix, Inc. Procédés d'utilisation de protéase tau
ES2763361T3 (es) * 2012-05-31 2020-05-28 Univ Osaka City Agente terapéutico o agente profiláctico para la demencia
CA2877397A1 (fr) 2012-07-03 2014-01-09 Washington University Anticorps diriges contre tau
TW202136296A (zh) * 2014-06-27 2021-10-01 美商C2N醫療診斷有限責任公司 人類化抗-tau抗體
EP3448875A4 (fr) * 2016-04-29 2020-04-08 Voyager Therapeutics, Inc. Compositions pour le traitement de maladies
WO2018060035A1 (fr) * 2016-09-30 2018-04-05 F. Hoffmann-La Roche Ag Dosage à double liaison à base de spr pour l'analyse fonctionnelle de molécules multispécifiques
CN110520440A (zh) 2017-02-17 2019-11-29 戴纳立制药公司 抗τ抗体及其使用方法
JP2018139530A (ja) * 2017-02-27 2018-09-13 帝人ファーマ株式会社 認知症治療又は予防のためのヒト化抗体及びその製造方法、並びにそれを用いた認知症治療剤又は予防剤
CN110691794B (zh) 2017-05-30 2023-10-27 帝人制药株式会社 抗igf-i受体抗体
CA3076022C (fr) 2017-10-02 2023-01-17 Merck Sharp & Dohme Corp. Composes monobactames de chromane pour le traitement d'infections bacteriennes
AU2018352308A1 (en) 2017-10-16 2020-03-19 Eisai R&D Management Co., Ltd. Anti-tau antibodies and uses thereof
US11667707B2 (en) 2018-04-06 2023-06-06 Teijin Pharma Limited SPNS2 neutralizing antibody
WO2020009151A1 (fr) * 2018-07-04 2020-01-09 国立大学法人名古屋大学 Oligonucléotides pour réguler l'épissage de la protéine tau, et leurs utilisations
CN110028583B (zh) * 2019-05-07 2020-09-11 温州医科大学 抗Tau抗体及其在治疗阿尔茨海默病、创伤性脑损伤中的应用
JP7429404B2 (ja) * 2019-08-06 2024-02-08 慶應義塾 タウ関連疾患モデルの製造方法
EP4040153A4 (fr) 2019-09-30 2023-07-26 Nipro Corporation Procédé de détection d'une protéine tau au moyen d'un échantillon de sang en tant que spécimen
EP4121071A4 (fr) * 2020-03-19 2024-07-24 Vascular Biosciences Peptide car pour survie améliorée de coronavirus
EP4171633A1 (fr) 2020-06-25 2023-05-03 Merck Sharp & Dohme LLC Anticorps à haute affinité ciblant la protéine tau phosphorylée à la position 413 de sérine
WO2023092004A1 (fr) 2021-11-17 2023-05-25 Voyager Therapeutics, Inc. Compositions et méthodes pour le traitement de troubles liés à tau

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS587390B2 (ja) 1975-03-11 1983-02-09 ツキシマキカイ カブシキガイシヤ ア−クヨウセツホウホウ
JP3587390B2 (ja) 1994-03-17 2004-11-10 タカラバイオ株式会社 リン酸化アミノ酸誘導体及びリン酸化ペプチド合成方法
US20020086009A1 (en) * 1996-03-13 2002-07-04 Koichi Ishiguro Anti-phosphorylated tau protein antibodies and methods for detecting alzheimer`s disease with the use of the same
US20080199471A1 (en) * 2002-03-01 2008-08-21 Bernett Matthew J Optimized cd40 antibodies and methods of using the same
US8012936B2 (en) * 2006-03-29 2011-09-06 New York University Tau fragments for immunotherapy
US20070280935A1 (en) * 2006-04-07 2007-12-06 Bernd Bohrmann Antibody that recognizes phosphorylated peptides
KR20090019864A (ko) * 2006-06-16 2009-02-25 엔비보 파마슈티칼즈, 인코퍼레이티드 Tau와 아밀로이드 전구체 단편을 발현하는 유전자도입 파리
UA107571C2 (xx) * 2009-04-03 2015-01-26 Фармацевтична композиція
EP3329932A1 (fr) * 2009-06-10 2018-06-06 New York University Ciblage immunologique de protéines tau pathologiques
US8609097B2 (en) 2009-06-10 2013-12-17 Hoffmann-La Roche Inc. Use of an anti-Tau pS422 antibody for the treatment of brain diseases
US8703137B2 (en) * 2011-01-31 2014-04-22 Intellect Neurosciences Inc. Treatment of tauopathies
TR201102696U (tr) * 2011-05-27 2011-06-21 Turhal Sal�H Bağlantısız hareketli ürün reklam standı.
ES2763361T3 (es) * 2012-05-31 2020-05-28 Univ Osaka City Agente terapéutico o agente profiláctico para la demencia

Also Published As

Publication number Publication date
MX2014014187A (es) 2015-06-04
RS59802B1 (sr) 2020-02-28
US20220340646A1 (en) 2022-10-27
KR20200029619A (ko) 2020-03-18
HRP20192267T1 (hr) 2020-03-20
SI2857039T1 (sl) 2020-03-31
ES2973070T3 (es) 2024-06-18
HUE046919T2 (hu) 2020-04-28
JP5971659B2 (ja) 2016-08-17
TW202041532A (zh) 2020-11-16
KR102208283B1 (ko) 2021-01-26
KR102133610B1 (ko) 2020-07-14
PH12014502669B1 (en) 2015-02-02
CA2875205C (fr) 2021-07-20
AU2018200413B2 (en) 2019-10-17
EP2857039A4 (fr) 2015-08-26
AU2018200413A1 (en) 2018-02-08
EP3662931B1 (fr) 2023-12-06
MY172458A (en) 2019-11-26
CN104602708A (zh) 2015-05-06
EP2857039B1 (fr) 2019-11-20
TWI700296B (zh) 2020-08-01
PH12014502669A1 (en) 2015-02-02
CA2875205A1 (fr) 2013-12-05
TWI777183B (zh) 2022-09-11
EP2857039A1 (fr) 2015-04-08
MX361128B (es) 2018-11-28
SG11201407878VA (en) 2015-01-29
TW201410705A (zh) 2014-03-16
ZA201409186B (en) 2015-12-23
PT2857039T (pt) 2020-01-07
WO2013180238A1 (fr) 2013-12-05
US20200148753A1 (en) 2020-05-14
ME03587B (fr) 2020-07-20
JP6406678B2 (ja) 2018-10-17
KR20150027098A (ko) 2015-03-11
CN104602708B (zh) 2021-11-30
JP2018111716A (ja) 2018-07-19
CY1122530T1 (el) 2021-01-27
IL235899B (en) 2019-03-31
JP6620829B2 (ja) 2019-12-18
RU2657438C2 (ru) 2018-06-13
ES2763361T3 (es) 2020-05-28
BR112014029566A2 (pt) 2017-07-25
PL2857039T3 (pl) 2020-05-18
LT2857039T (lt) 2020-03-10
AR091218A1 (es) 2015-01-21
EP3662931A1 (fr) 2020-06-10
AU2013268364B2 (en) 2018-02-08
DK2857039T3 (da) 2019-12-16
AU2013268364A1 (en) 2014-12-18
IL235899A0 (en) 2015-01-29
NZ630536A (en) 2017-03-31
JPWO2013180238A1 (ja) 2016-01-21
SG10201805410XA (en) 2018-08-30
US20150183854A1 (en) 2015-07-02
JP2016147902A (ja) 2016-08-18
RU2014153099A (ru) 2016-07-20

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