HK1210018A1 - Tailored liposomes for the treatment of bacterial infections - Google Patents

Tailored liposomes for the treatment of bacterial infections

Info

Publication number
HK1210018A1
HK1210018A1 HK15110746.9A HK15110746A HK1210018A1 HK 1210018 A1 HK1210018 A1 HK 1210018A1 HK 15110746 A HK15110746 A HK 15110746A HK 1210018 A1 HK1210018 A1 HK 1210018A1
Authority
HK
Hong Kong
Prior art keywords
treatment
bacterial infections
liposomes
tailored
tailored liposomes
Prior art date
Application number
HK15110746.9A
Other languages
English (en)
Chinese (zh)
Inventor
Eduard Babiychuk
Annette Draeger
Original Assignee
Universitt Bern
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Universitt Bern filed Critical Universitt Bern
Publication of HK1210018A1 publication Critical patent/HK1210018A1/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Liposomes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A61K31/569Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone substituted in position 17 alpha, e.g. ethisterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/683Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
    • A61K31/688Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols both hydroxy compounds having nitrogen atoms, e.g. sphingomyelins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Liposomes
    • A61K9/1271Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • A61P39/02Antidotes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Toxicology (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
HK15110746.9A 2012-06-14 2015-10-30 Tailored liposomes for the treatment of bacterial infections HK1210018A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP12171924 2012-06-14
EP13153039 2013-01-29
PCT/EP2013/062207 WO2013186286A1 (en) 2012-06-14 2013-06-13 Tailored liposomes for the treatment of bacterial infections

Publications (1)

Publication Number Publication Date
HK1210018A1 true HK1210018A1 (en) 2016-04-15

Family

ID=48703423

Family Applications (1)

Application Number Title Priority Date Filing Date
HK15110746.9A HK1210018A1 (en) 2012-06-14 2015-10-30 Tailored liposomes for the treatment of bacterial infections

Country Status (19)

Country Link
US (4) US10744089B2 (el)
EP (2) EP2861214B1 (el)
JP (2) JP6382801B2 (el)
CN (2) CN109549925B (el)
AU (2) AU2013276565B2 (el)
BR (1) BR112014031278B1 (el)
CA (1) CA2875470C (el)
CY (1) CY1123337T1 (el)
DK (1) DK2861214T3 (el)
ES (1) ES2821502T3 (el)
HK (1) HK1210018A1 (el)
HR (1) HRP20201761T1 (el)
HU (1) HUE051761T2 (el)
LT (1) LT2861214T (el)
PL (1) PL2861214T3 (el)
RS (1) RS60951B1 (el)
RU (1) RU2672106C2 (el)
SI (1) SI2861214T1 (el)
WO (1) WO2013186286A1 (el)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
LT2861214T (lt) * 2012-06-14 2020-12-28 Universität Bern Specialiai pritaikytos liposomos, skirtos bakterinių infekcijų gydymui
WO2015084677A1 (en) 2013-12-02 2015-06-11 Arytha Biosciences, Llc Toxoid preparation and uses thereof
US10739353B2 (en) * 2014-12-31 2020-08-11 Signpath Pharma, Inc. Suppression of cytokine release and cytokine storm
CA3009119A1 (en) * 2015-12-28 2017-07-06 Mb Biotech Ltd. Liposomes for treatment of an autoimmune disease
WO2017177073A1 (en) * 2016-04-07 2017-10-12 The United States Of America, As Represented By The Secretary, Department Of Health & Human Services Francisella lipids as broad anti-inflammatory therapeutics and associated methods of use
PT3471732T (pt) 2016-06-16 2020-08-24 Combioxin Sa Lipossomas para o tratamento de infeções virais
EP3589278A1 (en) * 2017-03-02 2020-01-08 Combioxin SA Liposomes for inhibiting biofilm formation
US11344497B1 (en) * 2017-12-08 2022-05-31 Quicksilver Scientific, Inc. Mitochondrial performance enhancement nanoemulsion
PL3781172T3 (pl) 2018-04-17 2024-02-12 Combioxin Sa Leczenie zapalenia płuc
US20210259967A1 (en) * 2018-04-20 2021-08-26 Combioxin Sa Treatment of sepsis and septic shock
CN111214439B (zh) * 2018-11-23 2023-02-10 复旦大学 一种具有细菌成孔毒素吸附性能的纳米药物系统及其用途
KR20230026468A (ko) * 2020-07-31 2023-02-24 사인패스 파마 인코포레이티드 사이토카인 방출 및 사이토카인 폭풍의 억제
CN115054577B (zh) * 2022-05-17 2024-06-21 温州医科大学附属第二医院(温州医科大学附属育英儿童医院) 纳米解毒剂及其在中和mrsa穿孔毒素的应用

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU6428890A (en) * 1989-09-12 1991-04-18 Regents Of The University Of California, The Therapeutic peptides and proteins
NL9000207A (el) * 1990-01-29 1991-08-16 Duphar Int Res
AU2583892A (en) * 1991-09-11 1993-04-05 Pitman-Moore, Inc. Method for enhancing the immune system in a host employing liposome-encapsulated polypeptides
US5741516A (en) * 1994-06-20 1998-04-21 Inex Pharmaceuticals Corporation Sphingosomes for enhanced drug delivery
US5543152A (en) * 1994-06-20 1996-08-06 Inex Pharmaceuticals Corporation Sphingosomes for enhanced drug delivery
US6726925B1 (en) * 1998-06-18 2004-04-27 Duke University Temperature-sensitive liposomal formulation
US8110217B2 (en) * 2001-08-13 2012-02-07 University Of Pittsburgh Sphingomyelin liposomes for the treatment of hyperactive bladder disorders
EP1443900B1 (en) * 2001-11-13 2012-05-23 Celator Pharmaceuticals, Inc. Lipid carrier compositions with enhanced blood stability
CA2368656A1 (en) * 2002-01-21 2003-07-21 Vasogen Ireland Limited Receptor-ligand pairing for anti-inflammatory response
EP1531828A4 (en) * 2002-05-23 2005-11-02 Activbiotics Inc METHODS OF TREATING BACTERIAL INFECTIONS AND ASSOCIATED DISEASES
EP1599183A2 (en) * 2002-11-26 2005-11-30 Gilead Sciences, Inc. Method of drug loading in liposomes by gradient
US20060198882A1 (en) * 2003-03-21 2006-09-07 Yechezkel Barenholz Stable liposomes or micelles comprising a sphinolipid and a peg-lipopolymer
WO2006052767A2 (en) * 2004-11-05 2006-05-18 Inex Pharmaceuticals Corporation Compositions and methods for stabilizing liposomal camptothecin formulations
CN1939340A (zh) * 2005-09-29 2007-04-04 中国人民解放军军事医学科学院毒物药物研究所 脂质体制剂
US20080131497A1 (en) * 2006-09-28 2008-06-05 Perkins Walter R Formulations of DNase and Methods of Use Thereof
US9637515B2 (en) * 2006-11-06 2017-05-02 Jina Pharmaceuticals, Inc. Guggulphospholipid methods and compositions
CN1994279A (zh) * 2006-12-31 2007-07-11 西安力邦医药科技有限责任公司 注射用盐酸伊立替康脂质体的制备方法
CN101623262B (zh) * 2009-08-24 2011-02-02 海南美大制药有限公司 一种五水头孢唑啉钠前体脂质体制剂
WO2012021107A2 (en) * 2010-08-12 2012-02-16 Nanyang Technological University A liposomal formulation for ocular drug delivery
CN102327220B (zh) 2011-07-14 2012-09-26 海南灵康制药有限公司 一种氯雷他定脂质体固体制剂
LT2861214T (lt) * 2012-06-14 2020-12-28 Universität Bern Specialiai pritaikytos liposomos, skirtos bakterinių infekcijų gydymui

Also Published As

Publication number Publication date
RS60951B1 (sr) 2020-11-30
CA2875470C (en) 2021-01-12
CN109549925B (zh) 2022-06-17
WO2013186286A1 (en) 2013-12-19
US20220087934A1 (en) 2022-03-24
RU2014148284A (ru) 2016-08-10
US20150157570A1 (en) 2015-06-11
EP3782606A1 (en) 2021-02-24
EP2861214A1 (en) 2015-04-22
HUE051761T2 (hu) 2021-03-29
JP2018184470A (ja) 2018-11-22
DK2861214T3 (da) 2020-10-12
PL2861214T3 (pl) 2021-02-08
RU2018138012A (ru) 2019-03-21
CY1123337T1 (el) 2021-12-31
CN104602672A (zh) 2015-05-06
ES2821502T3 (es) 2021-04-26
BR112014031278A2 (pt) 2017-06-27
AU2019201776B2 (en) 2020-11-12
JP6382801B2 (ja) 2018-08-29
US20230031648A1 (en) 2023-02-02
HRP20201761T1 (hr) 2020-12-25
CN104602672B (zh) 2018-12-25
SI2861214T1 (sl) 2021-01-29
EP2861214B1 (en) 2020-08-05
CN109549925A (zh) 2019-04-02
US10744089B2 (en) 2020-08-18
US20200345639A1 (en) 2020-11-05
BR112014031278B1 (pt) 2020-12-01
AU2019201776A1 (en) 2019-04-04
AU2013276565A1 (en) 2014-12-18
RU2672106C2 (ru) 2018-11-12
LT2861214T (lt) 2020-12-28
JP6656321B2 (ja) 2020-03-04
JP2015519383A (ja) 2015-07-09
CA2875470A1 (en) 2013-12-19
AU2013276565B2 (en) 2018-12-20

Similar Documents

Publication Publication Date Title
HK1210018A1 (en) Tailored liposomes for the treatment of bacterial infections
HK1211589A1 (en) Compounds for the treatment of paramoxyvirus viral infections
ZA201405820B (en) Piperidino-pyrimidine derivatives for the treatment of viral infections
ZA201500921B (en) Alkylpyrimidine derivatives for the treatment of viral infections and further diaseases
HK1209755A1 (en) Mannose derivatives for treating bacterial infections
HK1213544A1 (zh) 新型二環苯基-吡啶/吡嗪用於治療癌症
PL2696890T3 (pl) Leczenie infekcji drobnoustrojowych
GB201217097D0 (en) Treatment of bacterial infection
GB201212588D0 (en) Colicins for treating bacterial infections
AP2015008338A0 (en) Compounds for the treatment and prevention of retroviral infections
IL233486A0 (en) Synthetic peptides for the treatment of bacterial infections
EP2906216A4 (en) INHIBITORS OF THE DNA GYRASE FOR THE TREATMENT OF BACTERIAL INFECTIONS
HK1212619A1 (zh) 眼部感染的治療或預防方法
ZA201306342B (en) The treatment of viral infections
HK1208454A1 (zh) 治療細菌性疾病的嘧啶衍生物
ZA201308116B (en) Avian-based treatment for microbial infections
IL234796B (en) Compounds for the treatment of diseases related to ischemia-reperfusion
HK1210421A1 (en) Use of pregn-4-en-20-yn-3-one for the treatment of depressive disorders -4--20--3-
ZA201308806B (en) Liposomal vancomycin for the treatment of mrsa infections
EP2665738A4 (en) COMPOUNDS FOR TREATING BACTERIAL INFECTION
PT2861214T (pt) Lipossomas adaptados para o tratamento de infeções bacterianas
EP2670407A4 (en) TREATMENT OF BACTERIAL INFECTIONS
AU2012904839A0 (en) Phage therapy for the treatment of MRSA infections
AP2015008270A0 (en) Preparation for the treatment of tuberculosis
GB201212715D0 (en) Treatment of fungal infections