HK1206608A1 - 三唑並化合物 - Google Patents
三唑並化合物Info
- Publication number
- HK1206608A1 HK1206608A1 HK15107168.4A HK15107168A HK1206608A1 HK 1206608 A1 HK1206608 A1 HK 1206608A1 HK 15107168 A HK15107168 A HK 15107168A HK 1206608 A1 HK1206608 A1 HK 1206608A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- medication
- dispenser
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4196—1,2,4-Triazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/50—Pyridazines; Hydrogenated pyridazines
- A61K31/5025—Pyridazines; Hydrogenated pyridazines ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
- C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D249/14—Nitrogen atoms
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Epidemiology (AREA)
- Psychiatry (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Psychology (AREA)
- Addiction (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Obesity (AREA)
- Hospice & Palliative Care (AREA)
- Pain & Pain Management (AREA)
- Emergency Medicine (AREA)
- Oncology (AREA)
- Urology & Nephrology (AREA)
- Reproductive Health (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP12191607 | 2012-11-07 | ||
PCT/EP2013/072966 WO2014072261A1 (en) | 2012-11-07 | 2013-11-04 | Triazolo compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1206608A1 true HK1206608A1 (zh) | 2016-01-15 |
Family
ID=47143719
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK15107168.4A HK1206608A1 (zh) | 2012-11-07 | 2015-07-27 | 三唑並化合物 |
Country Status (12)
Country | Link |
---|---|
US (1) | US9617271B2 (zh) |
EP (1) | EP2916842B1 (zh) |
JP (1) | JP6293161B2 (zh) |
KR (1) | KR20150081354A (zh) |
CN (1) | CN104768554B (zh) |
BR (1) | BR112015009649A2 (zh) |
CA (1) | CA2888324A1 (zh) |
ES (1) | ES2603931T3 (zh) |
HK (1) | HK1206608A1 (zh) |
MX (1) | MX2015005375A (zh) |
RU (1) | RU2015118286A (zh) |
WO (1) | WO2014072261A1 (zh) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP3099690B1 (en) * | 2014-01-31 | 2019-08-28 | F.Hoffmann-La Roche Ag | (hetero)aryl imidazoles/pyrazoles for treatment of neurological disorders |
CN104086553B (zh) * | 2014-06-13 | 2016-04-27 | 南京药石科技股份有限公司 | 一种制备7-溴咪唑并[2,1-f][1,2,4]三嗪-4-胺的方法 |
TW201639851A (zh) * | 2015-03-16 | 2016-11-16 | 大日本住友製藥股份有限公司 | 雙環咪唑衍生物 |
US10112944B2 (en) * | 2015-03-18 | 2018-10-30 | Bristol-Myers Squibb Company | Heterocyclic compounds useful as inhibitors of TNF |
AU2016233289A1 (en) * | 2015-03-18 | 2017-11-09 | Bristol-Myers Squibb Company | Tricyclic heterocyclic compounds useful as inhibitors of TNF |
KR20190110106A (ko) * | 2017-01-06 | 2019-09-27 | 더 존스 홉킨스 유니버시티 | 신경퇴행성 질환의 치료를 위한 중성 스핑고미엘리나제 2(nSMAse2)의 저분자 억제제 |
KR102628073B1 (ko) | 2017-01-10 | 2024-01-22 | 바이엘 악티엔게젤샤프트 | 해충 방제제로서의 헤테로사이클 유도체 |
SG11202001684PA (en) | 2017-10-06 | 2020-03-30 | Forma Therapeutics Inc | Inhibiting ubiquitin specific peptidase 30 |
WO2020072964A1 (en) | 2018-10-05 | 2020-04-09 | Forma Therapeutics, Inc. | Fused pyrrolines which act as ubiquitin-specific protease 30 (usp30) inhibitors |
TW202031250A (zh) | 2018-11-06 | 2020-09-01 | 丹麥商H 朗德貝克公司 | 用於治療負性症狀和認知損傷之pde10a抑制劑 |
BR112020013697A2 (pt) | 2018-11-06 | 2020-12-01 | H. Lundbeck A/S | compostos para tratamento de sintomas negativos e comprometimentos cognitivos |
WO2020103939A1 (zh) * | 2018-11-22 | 2020-05-28 | 上海科技大学 | 三唑并环类化合物、其制备方法、中间体和应用 |
KR20210116488A (ko) | 2018-12-20 | 2021-09-27 | 인사이트 코포레이션 | 액티빈 수용체-유사 키나제-2의 억제제로서의 이미다조피리다진 및 이미다조피리딘 화합물 |
WO2021216951A1 (en) | 2020-04-24 | 2021-10-28 | Vanderbilt University | Condensed substituted hydropyrroles as antagonists of the muscarinic acetylcholine receptor m4 |
WO2021216949A1 (en) | 2020-04-24 | 2021-10-28 | Vanderbilt University | Condensed substituted hydropyrroles as antagonists of the muscarinic acetylcholine receptor m4 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1998004559A2 (en) * | 1996-07-25 | 1998-02-05 | Merck Sharp & Dohme Limited | Substituted triazolo-pyridazine derivatives as ligands for gaba receptors |
WO2005012485A2 (en) | 2003-07-31 | 2005-02-10 | Bayer Pharmaceuticals Corporation | Methods for treating diabetes and related disorders using pde10a inhibitors |
CA2575430A1 (en) * | 2004-08-03 | 2006-02-16 | Merck & Co., Inc. | 1,3-disubstituted heteroaryl nmda/nr2b antagonists |
WO2006128693A2 (en) | 2005-06-01 | 2006-12-07 | Ucb Pharma, S.A. | 2 -oxo-i -pyrrolidine derivatives/ processes for preparing them and their therapeutic use on the central nervous system |
US8501738B2 (en) * | 2009-06-23 | 2013-08-06 | Concert Pharmaceuticals, Inc. | Substituted triazolo-pyridazine derivatives |
US8586581B2 (en) * | 2009-12-17 | 2013-11-19 | Hoffmann-La Roche Inc | Ethynyl compounds useful for treatment of CNS disorders |
CN102791715B (zh) | 2009-12-31 | 2016-04-27 | 卡洛斯三世国家癌症研究中心基金会 | 用作激酶抑制剂的三环化合物 |
US8410117B2 (en) * | 2010-03-26 | 2013-04-02 | Hoffmann-La Roche Inc. | Imidazopyrimidine derivatives |
WO2012147890A1 (ja) * | 2011-04-27 | 2012-11-01 | 持田製薬株式会社 | 新規アゾール誘導体 |
WO2013178569A1 (en) * | 2012-05-30 | 2013-12-05 | F. Hoffmann-La Roche Ag | Pyrrolidino heterocycles |
AU2013269800A1 (en) * | 2012-05-30 | 2014-10-09 | F. Hoffmann-La Roche Ag | Triazolo compounds as PDE10 inhibitors |
-
2013
- 2013-11-04 ES ES13786468.2T patent/ES2603931T3/es active Active
- 2013-11-04 CA CA2888324A patent/CA2888324A1/en not_active Abandoned
- 2013-11-04 JP JP2015541098A patent/JP6293161B2/ja not_active Expired - Fee Related
- 2013-11-04 MX MX2015005375A patent/MX2015005375A/es unknown
- 2013-11-04 WO PCT/EP2013/072966 patent/WO2014072261A1/en active Application Filing
- 2013-11-04 CN CN201380057750.6A patent/CN104768554B/zh not_active Expired - Fee Related
- 2013-11-04 BR BR112015009649A patent/BR112015009649A2/pt not_active IP Right Cessation
- 2013-11-04 KR KR1020157014862A patent/KR20150081354A/ko not_active Application Discontinuation
- 2013-11-04 EP EP13786468.2A patent/EP2916842B1/en not_active Not-in-force
- 2013-11-04 RU RU2015118286A patent/RU2015118286A/ru not_active Application Discontinuation
-
2015
- 2015-05-06 US US14/705,140 patent/US9617271B2/en active Active
- 2015-07-27 HK HK15107168.4A patent/HK1206608A1/zh not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
WO2014072261A1 (en) | 2014-05-15 |
BR112015009649A2 (pt) | 2017-07-04 |
CA2888324A1 (en) | 2014-05-15 |
RU2015118286A (ru) | 2016-12-27 |
EP2916842B1 (en) | 2016-10-19 |
CN104768554B (zh) | 2018-04-17 |
US20150232472A1 (en) | 2015-08-20 |
JP2015536959A (ja) | 2015-12-24 |
CN104768554A (zh) | 2015-07-08 |
ES2603931T3 (es) | 2017-03-02 |
MX2015005375A (es) | 2015-07-21 |
US9617271B2 (en) | 2017-04-11 |
EP2916842A1 (en) | 2015-09-16 |
KR20150081354A (ko) | 2015-07-13 |
JP6293161B2 (ja) | 2018-03-14 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20221028 |