HK1204615A1 - (1r,4r)7-oxo-2-azabicyclo[2.2.2]oct-5-ene and derivatives thereof - Google Patents
(1r,4r)7-oxo-2-azabicyclo[2.2.2]oct-5-ene and derivatives thereof Download PDFInfo
- Publication number
- HK1204615A1 HK1204615A1 HK15105207.1A HK15105207A HK1204615A1 HK 1204615 A1 HK1204615 A1 HK 1204615A1 HK 15105207 A HK15105207 A HK 15105207A HK 1204615 A1 HK1204615 A1 HK 1204615A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- azabicyclo
- ene
- oxo
- oct
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/08—Bridged systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/06—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing isoquinuclidine ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
- C07D491/20—Spiro-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/12—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains three hetero rings
- C07D493/20—Spiro-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D495/20—Spiro-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Emergency Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261741798P | 2012-01-25 | 2012-01-25 | |
| US201261741798P | 2012-01-25 | ||
| PCT/US2013/022797 WO2013112622A1 (en) | 2012-01-25 | 2013-01-23 | (1r,4r) 7-oxo-2-azabicyclo[2.2.2]oct-5-ene and derivatives thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1204615A1 true HK1204615A1 (en) | 2015-11-27 |
Family
ID=48873876
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK15105207.1A HK1204615A1 (en) | 2012-01-25 | 2013-01-23 | (1r,4r)7-oxo-2-azabicyclo[2.2.2]oct-5-ene and derivatives thereof |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US20130267710A1 (https=) |
| EP (1) | EP2807158A4 (https=) |
| JP (1) | JP2015506371A (https=) |
| KR (1) | KR20140117380A (https=) |
| CN (2) | CN104169279A (https=) |
| AU (1) | AU2013212209A1 (https=) |
| CA (1) | CA2857969A1 (https=) |
| HK (1) | HK1204615A1 (https=) |
| IL (1) | IL233055A (https=) |
| RU (1) | RU2014124531A (https=) |
| WO (1) | WO2013112622A1 (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2942638C (en) | 2013-03-15 | 2026-03-10 | Demerx, Inc. | Method for noribogaine treatment of addiction in patients on methadone |
| US9561232B2 (en) | 2014-02-18 | 2017-02-07 | Demerx, Inc. | Low dose noribogaine for treating nicotine addiction and preventing relapse of nicotine use |
| US9591978B2 (en) | 2014-03-13 | 2017-03-14 | Demerx, Inc. | Methods and compositions for pre-screening patients for treatment with noribogaine |
| CA2989550C (en) * | 2014-06-18 | 2023-08-08 | Demerx, Inc. | Halogenated indole and benzofuran derivatives of isoquinuclidene and processes for preparing them |
| US9549935B2 (en) | 2014-07-14 | 2017-01-24 | Demerx, Inc. | Methods and compositions for treating migraines using noribogaine |
| AU2015353414B2 (en) | 2014-11-26 | 2021-04-29 | Demerx, Inc. | Methods and compositions for potentiating the action of opioid analgesics using iboga alkaloids |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5646289A (en) * | 1994-10-24 | 1997-07-08 | Eli Lilly And Company | Heterocyclic compounds and their preparation and use |
| FR2884516B1 (fr) * | 2005-04-15 | 2007-06-22 | Cerep Sa | Antagonistes npy, preparation et utilisations |
| JP2010229097A (ja) * | 2009-03-27 | 2010-10-14 | Tohoku Univ | 新規オキサゾリジン誘導体及び新規オキサゾリジン誘導体塩、並びに該オキサゾリジン誘導体塩を不斉有機分子触媒とした光学活性化合物の製造方法 |
| JP5622019B2 (ja) * | 2009-09-25 | 2014-11-12 | 国立大学法人東北大学 | アミノアルコール誘導体塩構造を有する不斉有機分子触媒及び該不斉有機分子触媒を用いた光学活性化合物の製造方法 |
| WO2013028999A1 (en) * | 2011-08-24 | 2013-02-28 | The Trustees Of Columbia University In The City Of New York | Small molecule inducers of gdnf as potential new therapeutics for neuropsychiatric disorders |
-
2013
- 2013-01-23 KR KR1020147018193A patent/KR20140117380A/ko not_active Withdrawn
- 2013-01-23 AU AU2013212209A patent/AU2013212209A1/en not_active Abandoned
- 2013-01-23 CA CA2857969A patent/CA2857969A1/en not_active Abandoned
- 2013-01-23 HK HK15105207.1A patent/HK1204615A1/xx unknown
- 2013-01-23 RU RU2014124531A patent/RU2014124531A/ru not_active Application Discontinuation
- 2013-01-23 EP EP13741387.8A patent/EP2807158A4/en not_active Withdrawn
- 2013-01-23 CN CN201380004353.2A patent/CN104169279A/zh active Pending
- 2013-01-23 CN CN201810010846.1A patent/CN108912117A/zh active Pending
- 2013-01-23 JP JP2014554804A patent/JP2015506371A/ja active Pending
- 2013-01-23 WO PCT/US2013/022797 patent/WO2013112622A1/en not_active Ceased
- 2013-01-24 US US13/749,592 patent/US20130267710A1/en not_active Abandoned
-
2014
- 2014-06-10 IL IL233055A patent/IL233055A/en active IP Right Grant
-
2017
- 2017-11-13 US US15/811,549 patent/US20180319800A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20130267710A1 (en) | 2013-10-10 |
| CN104169279A (zh) | 2014-11-26 |
| RU2014124531A (ru) | 2016-04-10 |
| EP2807158A4 (en) | 2015-11-18 |
| JP2015506371A (ja) | 2015-03-02 |
| IL233055A0 (en) | 2014-08-03 |
| AU2013212209A8 (en) | 2014-07-10 |
| AU2013212209A1 (en) | 2014-06-26 |
| WO2013112622A1 (en) | 2013-08-01 |
| US20180319800A1 (en) | 2018-11-08 |
| CA2857969A1 (en) | 2013-08-01 |
| EP2807158A1 (en) | 2014-12-03 |
| CN108912117A (zh) | 2018-11-30 |
| KR20140117380A (ko) | 2014-10-07 |
| IL233055A (en) | 2017-02-28 |
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