HK1204552A1 - Solubilized capsule formulation of 1,1-dimethylethyl [(1s)-1- [(2s,4r)-4-(7-chloro-4methoxyisoquinolin-1-yloxy)-2-((1r,2s)-1- [(cyclopropylsulfonyl)carbamoyl]-2- ethenylcyclopropylcarbamoyl)pyrrolidin-1-yl]carbonyl-2,2- dimethylpropyl]carbamate [(1s)-1-[(2s4r)-4-(7--4--1-)-2-((1r2s)-1- [()]-2-)-1-]- 22-] 11- - Google Patents

Solubilized capsule formulation of 1,1-dimethylethyl [(1s)-1- [(2s,4r)-4-(7-chloro-4methoxyisoquinolin-1-yloxy)-2-((1r,2s)-1- [(cyclopropylsulfonyl)carbamoyl]-2- ethenylcyclopropylcarbamoyl)pyrrolidin-1-yl]carbonyl-2,2- dimethylpropyl]carbamate [(1s)-1-[(2s4r)-4-(7--4--1-)-2-((1r2s)-1- [()]-2-)-1-]- 22-] 11-

Info

Publication number
HK1204552A1
HK1204552A1 HK15105032.2A HK15105032A HK1204552A1 HK 1204552 A1 HK1204552 A1 HK 1204552A1 HK 15105032 A HK15105032 A HK 15105032A HK 1204552 A1 HK1204552 A1 HK 1204552A1
Authority
HK
Hong Kong
Prior art keywords
ethenylcyclopropylcarbamoyl
cyclopropylsulfonyl
dimethylpropyl
dimethylethyl
yloxy
Prior art date
Application number
HK15105032.2A
Other languages
English (en)
Chinese (zh)
Inventor
Robert Kevin Perrone
Original Assignee
Bristol Myers Squibb Holdings Ireland
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=48428670&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1204552(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bristol Myers Squibb Holdings Ireland filed Critical Bristol Myers Squibb Holdings Ireland
Publication of HK1204552A1 publication Critical patent/HK1204552A1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/472—Non-condensed isoquinolines, e.g. papaverine
    • A61K31/4725—Non-condensed isoquinolines, e.g. papaverine containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/06—Tripeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
HK15105032.2A 2012-05-07 2015-05-27 Solubilized capsule formulation of 1,1-dimethylethyl [(1s)-1- [(2s,4r)-4-(7-chloro-4methoxyisoquinolin-1-yloxy)-2-((1r,2s)-1- [(cyclopropylsulfonyl)carbamoyl]-2- ethenylcyclopropylcarbamoyl)pyrrolidin-1-yl]carbonyl-2,2- dimethylpropyl]carbamate [(1s)-1-[(2s4r)-4-(7--4--1-)-2-((1r2s)-1- [()]-2-)-1-]- 22-] 11- HK1204552A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261643454P 2012-05-07 2012-05-07
PCT/US2013/038770 WO2013169520A1 (en) 2012-05-07 2013-04-30 Solubilized capsule formulation of 1,1-dimethylethyl [(1s)-1-{[(2s,4r)-4-(7-chloro-4methoxyisoquinolin-1-yloxy)-2-({(1r,2s)-1-[(cyclopropylsulfonyl)carbamoyl]-2-ethenylcyclopropyl}carbamoyl)pyrrolidin-1-yl]carbonyl}-2,2-dimethylpropyl]carbamate

Publications (1)

Publication Number Publication Date
HK1204552A1 true HK1204552A1 (en) 2015-11-27

Family

ID=48428670

Family Applications (1)

Application Number Title Priority Date Filing Date
HK15105032.2A HK1204552A1 (en) 2012-05-07 2015-05-27 Solubilized capsule formulation of 1,1-dimethylethyl [(1s)-1- [(2s,4r)-4-(7-chloro-4methoxyisoquinolin-1-yloxy)-2-((1r,2s)-1- [(cyclopropylsulfonyl)carbamoyl]-2- ethenylcyclopropylcarbamoyl)pyrrolidin-1-yl]carbonyl-2,2- dimethylpropyl]carbamate [(1s)-1-[(2s4r)-4-(7--4--1-)-2-((1r2s)-1- [()]-2-)-1-]- 22-] 11-

Country Status (33)

Country Link
US (1) US20130302414A1 (ru)
EP (1) EP2846780B1 (ru)
JP (1) JP6276756B2 (ru)
KR (1) KR20150004921A (ru)
CN (1) CN104363899A (ru)
AR (1) AR090954A1 (ru)
AU (1) AU2013260005B2 (ru)
BR (1) BR112014027676A2 (ru)
CA (1) CA2872765A1 (ru)
CL (1) CL2014003012A1 (ru)
CO (1) CO7141457A2 (ru)
CY (1) CY1120756T1 (ru)
DK (1) DK2846780T3 (ru)
EA (1) EA028749B1 (ru)
ES (1) ES2688817T3 (ru)
HK (1) HK1204552A1 (ru)
HR (1) HRP20181583T1 (ru)
IL (1) IL235466B (ru)
LT (1) LT2846780T (ru)
MX (1) MX358545B (ru)
MY (1) MY171378A (ru)
NZ (1) NZ630248A (ru)
PE (1) PE20142439A1 (ru)
PH (1) PH12014502405A1 (ru)
PL (1) PL2846780T3 (ru)
PT (1) PT2846780T (ru)
RS (1) RS57881B1 (ru)
SG (1) SG11201406964QA (ru)
SI (1) SI2846780T1 (ru)
TW (1) TWI577392B (ru)
UY (1) UY34785A (ru)
WO (1) WO2013169520A1 (ru)
ZA (1) ZA201408967B (ru)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013169577A1 (en) * 2012-05-07 2013-11-14 Bristol-Myers Squibb Company Oral solid dosage formulation of 1,1-dimethylethyl [(1s)-1-{[(2s,4r)-4-(7-chloro-4methoxyisoquinolin-1-yloxy)-2-({(1r,2s)-1-[(cyclopropylsulfonyl)carbamoyl]-2-ethenylcyclopropyl}carbamoyl)pyrrolidin-1-yl]carbonyl}-2,2-dimethylpropyl]carbamate
LT2909205T (lt) 2012-10-19 2016-12-27 Bristol-Myers Squibb Company 9-metilpakeistieji heksadekahidrociklopropa(e)pirolo (1,2-a)(1,4)diazaciklopentadecinilkarbamato dariniai, kaip nestruktūrinės 3 (ns3) proteazės inhibitoriai, skirti hepatito c viruso infekcijų gydymui
US9598433B2 (en) 2012-11-02 2017-03-21 Bristol-Myers Squibb Company Hepatitis C virus inhibitors
US9643999B2 (en) 2012-11-02 2017-05-09 Bristol-Myers Squibb Company Hepatitis C virus inhibitors
EP2914598B1 (en) 2012-11-02 2017-10-18 Bristol-Myers Squibb Company Hepatitis c virus inhibitors
EP2914614B1 (en) 2012-11-05 2017-08-16 Bristol-Myers Squibb Company Hepatitis c virus inhibitors
EP2964664B1 (en) 2013-03-07 2017-01-11 Bristol-Myers Squibb Company Hepatitis c virus inhibitors
WO2019130341A1 (en) * 2017-12-26 2019-07-04 Hetero Labs Limited Capsule compositions comprising lopinavir and ritonavir

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA9710071B (en) * 1996-11-21 1998-05-25 Abbott Lab Pharmaceutical composition.
SK6572003A3 (en) * 2000-10-31 2003-10-07 Boehringer Ingelheim Pharma Oral self-emulsifying formulations of pyranone protease inhibitors
US6828301B2 (en) * 2002-02-07 2004-12-07 Boehringer Ingelheim International Gmbh Pharmaceutical compositions for hepatitis C viral protease inhibitors
MY140680A (en) 2002-05-20 2010-01-15 Bristol Myers Squibb Co Hepatitis c virus inhibitors
TWI480272B (zh) * 2008-10-09 2015-04-11 Anadys Pharmaceuticals Inc 藉由５，６－二氫－１ｈ－吡啶－２－酮與一或多種其他抗病毒化合物的組合物抑制ｃ型肝炎病毒的方法
US8252821B2 (en) * 2009-04-14 2012-08-28 Bristol-Myers Squibb Company Bioavailable capsule compositions of amorphous alpha-(N-sulfonamido)acetamide compound

Also Published As

Publication number Publication date
KR20150004921A (ko) 2015-01-13
UY34785A (es) 2013-11-29
IL235466B (en) 2019-03-31
EP2846780B1 (en) 2018-07-18
PH12014502405A1 (en) 2015-01-12
ES2688817T3 (es) 2018-11-07
EA028749B1 (ru) 2017-12-29
WO2013169520A1 (en) 2013-11-14
EA201492039A1 (ru) 2015-02-27
RS57881B1 (sr) 2019-01-31
AR090954A1 (es) 2014-12-17
SG11201406964QA (en) 2014-11-27
TW201350145A (zh) 2013-12-16
LT2846780T (lt) 2018-11-12
PL2846780T3 (pl) 2018-11-30
JP2015516418A (ja) 2015-06-11
US20130302414A1 (en) 2013-11-14
NZ630248A (en) 2016-11-25
BR112014027676A2 (pt) 2017-06-27
MX358545B (es) 2018-08-24
CY1120756T1 (el) 2019-12-11
CA2872765A1 (en) 2013-11-14
AU2013260005A1 (en) 2015-01-15
DK2846780T3 (en) 2018-09-17
SI2846780T1 (sl) 2018-09-28
MY171378A (en) 2019-10-10
PT2846780T (pt) 2018-10-26
EP2846780A1 (en) 2015-03-18
JP6276756B2 (ja) 2018-02-07
TWI577392B (zh) 2017-04-11
AU2013260005B2 (en) 2017-07-13
PE20142439A1 (es) 2015-01-28
ZA201408967B (en) 2016-10-26
CN104363899A (zh) 2015-02-18
MX2014013220A (es) 2015-05-11
HRP20181583T1 (hr) 2018-11-30
CL2014003012A1 (es) 2015-07-10
CO7141457A2 (es) 2014-12-12

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20230427