HK1203490A1 - 扎托布洛芬及其衍生物的製造方法 - Google Patents

扎托布洛芬及其衍生物的製造方法

Info

Publication number
HK1203490A1
HK1203490A1 HK15103875.7A HK15103875A HK1203490A1 HK 1203490 A1 HK1203490 A1 HK 1203490A1 HK 15103875 A HK15103875 A HK 15103875A HK 1203490 A1 HK1203490 A1 HK 1203490A1
Authority
HK
Hong Kong
Prior art keywords
derivative
zaltoprofen
producing
producing zaltoprofen
Prior art date
Application number
HK15103875.7A
Other languages
English (en)
Inventor
Atsushi Tendo
Original Assignee
Nippon Chemiphar Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nippon Chemiphar Co filed Critical Nippon Chemiphar Co
Publication of HK1203490A1 publication Critical patent/HK1203490A1/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D337/00—Heterocyclic compounds containing rings of more than six members having one sulfur atom as the only ring hetero atom
    • C07D337/02—Seven-membered rings
    • C07D337/06—Seven-membered rings condensed with carbocyclic rings or ring systems
    • C07D337/10—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with two six-membered rings
    • C07D337/14—[b,f]-condensed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Rheumatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
HK15103875.7A 2012-04-24 2015-04-22 扎托布洛芬及其衍生物的製造方法 HK1203490A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2012098736 2012-04-24
PCT/JP2013/061974 WO2013161842A1 (ja) 2012-04-24 2013-04-24 ザルトプロフェンおよびその誘導体の製造方法

Publications (1)

Publication Number Publication Date
HK1203490A1 true HK1203490A1 (zh) 2015-10-30

Family

ID=49483150

Family Applications (1)

Application Number Title Priority Date Filing Date
HK15103875.7A HK1203490A1 (zh) 2012-04-24 2015-04-22 扎托布洛芬及其衍生物的製造方法

Country Status (7)

Country Link
EP (1) EP2842952A4 (zh)
JP (1) JP5937679B2 (zh)
KR (1) KR101677970B1 (zh)
CN (1) CN104185633B (zh)
HK (1) HK1203490A1 (zh)
SG (1) SG11201406873QA (zh)
WO (1) WO2013161842A1 (zh)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105198858B (zh) * 2015-10-30 2017-07-21 天津药物研究院药业有限责任公司 扎托布洛芬的纯化方法
CN105218514A (zh) * 2015-10-30 2016-01-06 天津药物研究院药业有限责任公司 扎托布洛芬的制备方法
CN110407804A (zh) * 2019-07-18 2019-11-05 河南后羿制药有限公司 微通道反应器在扎托布洛芬的环合反应中的应用及扎托布洛芬的环合方法
CN110590737B (zh) * 2019-09-25 2021-04-13 华中农业大学 一种高比活度氚标记扎托布洛芬及其制备方法
CN113200973B (zh) * 2021-04-22 2022-07-26 华中农业大学 一种基于扎托布洛芬母体结构的化合物及其抗炎用途

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5553282A (en) 1978-10-17 1980-04-18 Nippon Chemiphar Co Ltd Dibenzothiepin derivative and its preparation
JPS57106678A (en) 1980-12-23 1982-07-02 Nippon Chemiphar Co Ltd Preparation of dibenzothiepinpropionic acid derivative
JPS57171991A (en) 1981-04-14 1982-10-22 Fuji Photo Film Co Ltd Preparation of 2-(10,11-dihydro-10-oxodibenzo(b,f)thiepin-2- yl)propionic acid
JPS61251682A (ja) 1985-04-30 1986-11-08 Sankyo Kagaku Kk ２−（１０，１１−ジヒドロ−１０−オキソジベンゾ〔ｂ，ｆ〕チエピン−２−イル）プロピオン酸の製造方法
JPH0651697B2 (ja) 1985-11-07 1994-07-06 日本ケミフア株式会社 ２−（１０，１１−ジヒドロ−１０−オキソジベンゾ〔ｂ，ｆ〕チエピン−２−イル）プロピオン酸の精製法
JP2612161B2 (ja) 1986-06-10 1997-05-21 日本ケミファ 株式会社 ジベンゾチエピン誘導体の製造法
JP2549997B2 (ja) 1995-04-24 1996-10-30 日本ケミファ株式会社 新規ハロケタール化合物
JP4603276B2 (ja) 2004-03-05 2010-12-22 茂治 前川 ジベンゾチエピンプロピオン酸誘導体の製造方法
JP2005289949A (ja) 2004-04-06 2005-10-20 Tokuyama Corp ケトン化合物の製造方法
JP2006160766A (ja) 2005-02-22 2006-06-22 Mitsubishi Pharma Corp （±）２−（ジメチルアミノ）−１−｛〔Ｏ−（ｍ−メトキシフェネチル）フェノキシ〕メチル｝エチル水素サクシナート塩酸塩の結晶
JP2006273731A (ja) * 2005-03-28 2006-10-12 Tokuyama Corp ２−（１０、１１−ジヒドロ−１０−オキシジベンゾ〔ｂ、ｆ〕チエピン−２−イル）プロピオン酸の製造方法
JP2006290753A (ja) * 2005-04-06 2006-10-26 Tokuyama Corp ２−（１０、１１−ジヒドロ−１０−オキシジベンゾ〔ｂ、ｆ〕チエピン−２−イル）プロピオン酸の製造方法

Also Published As

Publication number Publication date
KR101677970B1 (ko) 2016-11-21
WO2013161842A1 (ja) 2013-10-31
CN104185633B (zh) 2018-01-30
EP2842952A4 (en) 2015-09-09
JPWO2013161842A1 (ja) 2015-12-24
SG11201406873QA (en) 2014-12-30
EP2842952A1 (en) 2015-03-04
KR20140132737A (ko) 2014-11-18
CN104185633A (zh) 2014-12-03
JP5937679B2 (ja) 2016-06-22

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