HK1203157A1 - Sustained delivery of molecules using peptide surfactants and uses thereof - Google Patents

Sustained delivery of molecules using peptide surfactants and uses thereof

Info

Publication number
HK1203157A1
HK1203157A1 HK15103754.3A HK15103754A HK1203157A1 HK 1203157 A1 HK1203157 A1 HK 1203157A1 HK 15103754 A HK15103754 A HK 15103754A HK 1203157 A1 HK1203157 A1 HK 1203157A1
Authority
HK
Hong Kong
Prior art keywords
molecules
sustained delivery
peptide surfactants
surfactants
peptide
Prior art date
Application number
HK15103754.3A
Other languages
English (en)
Chinese (zh)
Inventor
Sotirios Koutsopoulos
Shuguang Zhang
Original Assignee
Massachusetts Inst Technology
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Massachusetts Inst Technology filed Critical Massachusetts Inst Technology
Publication of HK1203157A1 publication Critical patent/HK1203157A1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/5123—Organic compounds, e.g. fats, sugars
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
    • A61K9/1273—Polymersomes; Liposomes with polymerisable or polymerised bilayer-forming substances

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Inorganic Chemistry (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Dispersion Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Nanotechnology (AREA)
  • Optics & Photonics (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HK15103754.3A 2012-05-31 2015-04-17 Sustained delivery of molecules using peptide surfactants and uses thereof HK1203157A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261653782P 2012-05-31 2012-05-31
PCT/US2013/043572 WO2013181511A1 (en) 2012-05-31 2013-05-31 Sustained delivery of molecules using peptide surfactants and uses thereof

Publications (1)

Publication Number Publication Date
HK1203157A1 true HK1203157A1 (en) 2015-10-23

Family

ID=49673920

Family Applications (1)

Application Number Title Priority Date Filing Date
HK15103754.3A HK1203157A1 (en) 2012-05-31 2015-04-17 Sustained delivery of molecules using peptide surfactants and uses thereof

Country Status (7)

Country Link
US (1) US20150147384A1 (ja)
EP (1) EP2854778A4 (ja)
JP (2) JP2015519374A (ja)
CA (1) CA2874003A1 (ja)
HK (1) HK1203157A1 (ja)
SG (1) SG11201407696WA (ja)
WO (1) WO2013181511A1 (ja)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014152751A1 (en) 2013-03-14 2014-09-25 Massachusetts Institute Of Technology Multi-layered injectable self-assembling peptide scaffold hydrogels for long-term sustained release of human antibodies
CN106832000B (zh) * 2017-01-17 2021-06-22 国家纳米科学中心 一种可在肿瘤细胞溶酶体内发生形貌转换的多肽脂质体
US11311568B2 (en) * 2017-11-09 2022-04-26 Purmx Therapeutics, Inc. Therapeutic pharmaceutical composition for cancer including miRNA
US11324703B2 (en) 2017-12-15 2022-05-10 3-D Matrix, Ltd. Surfactant peptide nanostructures and uses thereof in drug delivery

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7179784B2 (en) * 2001-07-10 2007-02-20 Massachusetts Institute Of Technology Surfactant peptide nanostructures, and uses thereof
JP3959453B2 (ja) * 2002-03-14 2007-08-15 沖電気工業株式会社 翻訳仲介システム及び翻訳仲介サーバ
US8187621B2 (en) * 2005-04-19 2012-05-29 Advanced Cardiovascular Systems, Inc. Methods and compositions for treating post-myocardial infarction damage
WO2008136820A1 (en) * 2007-05-01 2008-11-13 Massachusetts Institute Of Technology Stabilization of mammalian membrane proteins by short surfactant peptides
US20090069547A1 (en) * 2007-05-01 2009-03-12 Massachusetts Institute Of Technology Stabilization of mammalian membrane proteins by short surfactant peptides
WO2009018467A2 (en) * 2007-07-31 2009-02-05 Massachusetts Institute Of Technology Bio-sensing nanodevice
WO2010014903A1 (en) * 2008-07-31 2010-02-04 Massachusetts Institute Of Technology Multiplexed olfactory receptor-based microsurface plasmon polariton detector
KR101647521B1 (ko) * 2008-08-27 2016-08-10 가부시끼가이샤 쓰리디 매트릭스 트랜스펙션제
JP2010222338A (ja) * 2009-02-27 2010-10-07 Three D Matrix:Kk 核酸移送担体
JP2011012042A (ja) * 2009-07-03 2011-01-20 Three D Matrix:Kk 核酸徐放担体
JP2011126855A (ja) * 2009-12-15 2011-06-30 Three D Matrix:Kk タンパク質の凝集抑制剤

Also Published As

Publication number Publication date
WO2013181511A1 (en) 2013-12-05
EP2854778A4 (en) 2016-03-30
JP2018052935A (ja) 2018-04-05
EP2854778A1 (en) 2015-04-08
US20150147384A1 (en) 2015-05-28
CA2874003A1 (en) 2013-12-05
SG11201407696WA (en) 2014-12-30
JP2015519374A (ja) 2015-07-09

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