HK1201048A1 - Treatment of obesity and obesity-related disorders by pharmacological targeting of kv1.3 potassium channels kv13 - Google Patents

Treatment of obesity and obesity-related disorders by pharmacological targeting of kv1.3 potassium channels kv13

Info

Publication number
HK1201048A1
HK1201048A1 HK15101586.1A HK15101586A HK1201048A1 HK 1201048 A1 HK1201048 A1 HK 1201048A1 HK 15101586 A HK15101586 A HK 15101586A HK 1201048 A1 HK1201048 A1 HK 1201048A1
Authority
HK
Hong Kong
Prior art keywords
obesity
treatment
related disorders
potassium channels
pharmacological targeting
Prior art date
Application number
HK15101586.1A
Other languages
English (en)
Chinese (zh)
Inventor
George K Chandy
Sanjeev Kumar Upadhayay
Ping H Wang
Paolo Sassone Corsi
Kristin Lynn-Eckel Mahan
Shawn Iadonato
Joseph Mukergee
Reza M Mirbolooki
Original Assignee
Univ California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ California filed Critical Univ California
Publication of HK1201048A1 publication Critical patent/HK1201048A1/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1767Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43595Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from coelenteratae, e.g. medusae
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
HK15101586.1A 2011-10-03 2015-02-13 Treatment of obesity and obesity-related disorders by pharmacological targeting of kv1.3 potassium channels kv13 HK1201048A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161542751P 2011-10-03 2011-10-03
PCT/US2012/058495 WO2013052507A1 (en) 2011-10-03 2012-10-02 TREATMENT OF OBESITY AND OBESITY-RELATED DISORDERS BY PHARMACOLOGICAL TARGETING OF Kv1.3 POTASSIUM CHANNELS

Publications (1)

Publication Number Publication Date
HK1201048A1 true HK1201048A1 (en) 2015-08-21

Family

ID=48044112

Family Applications (1)

Application Number Title Priority Date Filing Date
HK15101586.1A HK1201048A1 (en) 2011-10-03 2015-02-13 Treatment of obesity and obesity-related disorders by pharmacological targeting of kv1.3 potassium channels kv13

Country Status (16)

Country Link
US (2) US20150072940A1 (da)
EP (1) EP2763702A4 (da)
JP (1) JP2014531469A (da)
KR (1) KR20140108518A (da)
CN (1) CN103987408A (da)
AU (1) AU2012318736A1 (da)
BR (1) BR112014008065A2 (da)
CA (1) CA2850357A1 (da)
HK (1) HK1201048A1 (da)
IL (1) IL231873A0 (da)
IN (1) IN2014CN03333A (da)
MX (1) MX2014004029A (da)
RU (1) RU2014117558A (da)
SG (1) SG11201401193XA (da)
TW (1) TW201321403A (da)
WO (1) WO2013052507A1 (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1796709A4 (en) * 2004-10-07 2009-10-28 Univ California ANALOGUE OF SHK-TOXIN AND ITS USE AS SELECTIVE INHIBITORS OF KV1.3-KALIUM CHANNELS
RU2637085C2 (ru) 2011-06-06 2017-11-29 КИНЕТА УАН, ЭлЭлСи Фармацевтические композиции на основе shk и способы их получения и использования
BR112014008065A2 (pt) 2011-10-03 2019-09-24 Kineta One Llc tratamento de obesidade e distúrbios relacionados a obesidade por direcionamento farmacológico de canais de potássio kv1.3
ES2975708T3 (es) * 2015-01-29 2024-07-12 Novo Nordisk As Comprimidos que comprenden agonista del GLP-1 y recubrimiento entérico
TWI698438B (zh) 2015-03-13 2020-07-11 德商4Sc製藥公司 Kv1.3抑制劑及其醫學應用
TWI701249B (zh) 2015-03-13 2020-08-11 德商4Sc製藥公司 Kv1.3抑制劑及其醫學應用

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5453270A (en) 1992-03-30 1995-09-26 Hypermetabolic Therapies, Inc. Pharmaceutical composition and method for hypermetabolic weight loss
US6077680A (en) * 1996-11-27 2000-06-20 The University Of Florida ShK toxin compositions and methods of use
AU8052798A (en) * 1997-09-17 1999-04-05 Bachem Bioscience, Inc. Polypeptide compositions that inhibit potassium channel activity and uses herefor
JP3207823B2 (ja) 1999-04-28 2001-09-10 リノール油脂株式会社 共役リノール酸を有効成分とする褐色脂肪増加剤
US6616944B2 (en) 2000-03-08 2003-09-09 Medinnova Gesellschaft Fur Medizinsche Innovationen Aus Adkademischer Forschung Mbh Self-assembling colloidal carriers for protein delivery
US6861405B2 (en) * 2001-06-12 2005-03-01 Yale University Compositions and methods relating to glucose metabolism, weight control, and food intake
EP1796709A4 (en) 2004-10-07 2009-10-28 Univ California ANALOGUE OF SHK-TOXIN AND ITS USE AS SELECTIVE INHIBITORS OF KV1.3-KALIUM CHANNELS
US7833979B2 (en) * 2005-04-22 2010-11-16 Amgen Inc. Toxin peptide therapeutic agents
EP1928463A2 (en) * 2005-08-17 2008-06-11 Solvay Pharmaceuticals GmbH Method of using potassium channel inhibiting compounds
AR074558A1 (es) * 2008-12-12 2011-01-26 Solvay Pharm Bv Espiro azepan oxazolidinonas como bloqueadores del canal de potasio kv1.3
BR112014008065A2 (pt) 2011-10-03 2019-09-24 Kineta One Llc tratamento de obesidade e distúrbios relacionados a obesidade por direcionamento farmacológico de canais de potássio kv1.3

Also Published As

Publication number Publication date
MX2014004029A (es) 2014-08-01
US9878006B2 (en) 2018-01-30
WO2013052507A1 (en) 2013-04-11
US20170095530A1 (en) 2017-04-06
IL231873A0 (en) 2014-05-28
KR20140108518A (ko) 2014-09-11
RU2014117558A (ru) 2015-11-10
CN103987408A (zh) 2014-08-13
US20150072940A1 (en) 2015-03-12
EP2763702A1 (en) 2014-08-13
SG11201401193XA (en) 2014-05-29
CA2850357A1 (en) 2013-04-11
EP2763702A4 (en) 2015-04-15
TW201321403A (zh) 2013-06-01
AU2012318736A1 (en) 2014-05-22
JP2014531469A (ja) 2014-11-27
BR112014008065A2 (pt) 2019-09-24
IN2014CN03333A (da) 2015-07-03

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