IN2014CN03333A - - Google Patents
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- Publication number
- IN2014CN03333A IN2014CN03333A IN3333CHN2014A IN2014CN03333A IN 2014CN03333 A IN2014CN03333 A IN 2014CN03333A IN 3333CHN2014 A IN3333CHN2014 A IN 3333CHN2014A IN 2014CN03333 A IN2014CN03333 A IN 2014CN03333A
- Authority
- IN
- India
- Prior art keywords
- shk
- potassium channel
- inhibiting agent
- modified
- obesity
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1767—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
- C07K14/43595—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from coelenteratae, e.g. medusae
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Abstract
Activation of brown adipose tissue treatment of obesity and/or treatment of obesity related disorders in human or non human animal subjects by administering to the subject a potassium channel inhibiting agent. The potassium channel inhibiting agent may comprise ShK toxin or a modified ShK toxin. Examples of modified ShK toxins include ShK 186.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201161542751P | 2011-10-03 | 2011-10-03 | |
PCT/US2012/058495 WO2013052507A1 (en) | 2011-10-03 | 2012-10-02 | TREATMENT OF OBESITY AND OBESITY-RELATED DISORDERS BY PHARMACOLOGICAL TARGETING OF Kv1.3 POTASSIUM CHANNELS |
Publications (1)
Publication Number | Publication Date |
---|---|
IN2014CN03333A true IN2014CN03333A (en) | 2015-07-03 |
Family
ID=48044112
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IN3333CHN2014 IN2014CN03333A (en) | 2011-10-03 | 2012-10-02 |
Country Status (16)
Country | Link |
---|---|
US (2) | US20150072940A1 (en) |
EP (1) | EP2763702A4 (en) |
JP (1) | JP2014531469A (en) |
KR (1) | KR20140108518A (en) |
CN (1) | CN103987408A (en) |
AU (1) | AU2012318736A1 (en) |
BR (1) | BR112014008065A2 (en) |
CA (1) | CA2850357A1 (en) |
HK (1) | HK1201048A1 (en) |
IL (1) | IL231873A0 (en) |
IN (1) | IN2014CN03333A (en) |
MX (1) | MX2014004029A (en) |
RU (1) | RU2014117558A (en) |
SG (1) | SG11201401193XA (en) |
TW (1) | TW201321403A (en) |
WO (1) | WO2013052507A1 (en) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2005294124B2 (en) * | 2004-10-07 | 2012-02-23 | Bachem Biosciences, Inc. | Analogs of ShK toxin and their uses in selective inhibition of Kv1.3 potassium channels |
TWI535455B (en) | 2011-06-06 | 2016-06-01 | 奇尼塔一有限責任公司 | Shk-based pharmaceutical compositions and methods of manufacturing and using the same |
WO2013052507A1 (en) | 2011-10-03 | 2013-04-11 | The Regents Of The University Of California | TREATMENT OF OBESITY AND OBESITY-RELATED DISORDERS BY PHARMACOLOGICAL TARGETING OF Kv1.3 POTASSIUM CHANNELS |
JP7211704B2 (en) * | 2015-01-29 | 2023-01-24 | ノヴォ ノルディスク アー/エス | A tablet containing a GLP-1 agonist and an enteric coating |
TWI698438B (en) | 2015-03-13 | 2020-07-11 | 德商4Sc製藥公司 | Kv1.3 inhibitors and their medical application |
TWI701249B (en) | 2015-03-13 | 2020-08-11 | 德商4Sc製藥公司 | Kv1.3 inhibitors and their medical application |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5453270A (en) | 1992-03-30 | 1995-09-26 | Hypermetabolic Therapies, Inc. | Pharmaceutical composition and method for hypermetabolic weight loss |
US6077680A (en) * | 1996-11-27 | 2000-06-20 | The University Of Florida | ShK toxin compositions and methods of use |
WO1999013895A1 (en) * | 1997-09-17 | 1999-03-25 | University Of Florida | Polypeptide compositions that inhibit potassium channel activity and uses therefor |
JP3207823B2 (en) | 1999-04-28 | 2001-09-10 | リノール油脂株式会社 | Brown fat enhancer containing conjugated linoleic acid as active ingredient |
US6616944B2 (en) | 2000-03-08 | 2003-09-09 | Medinnova Gesellschaft Fur Medizinsche Innovationen Aus Adkademischer Forschung Mbh | Self-assembling colloidal carriers for protein delivery |
US6861405B2 (en) * | 2001-06-12 | 2005-03-01 | Yale University | Compositions and methods relating to glucose metabolism, weight control, and food intake |
AU2005294124B2 (en) * | 2004-10-07 | 2012-02-23 | Bachem Biosciences, Inc. | Analogs of ShK toxin and their uses in selective inhibition of Kv1.3 potassium channels |
US7833979B2 (en) * | 2005-04-22 | 2010-11-16 | Amgen Inc. | Toxin peptide therapeutic agents |
BRPI0616995A2 (en) * | 2005-08-17 | 2011-07-05 | Solvay Pharm Gmbh | pharmaceutical composition, and use of kv1.3 potassium channel inhibitor in drug preparation |
TW201026708A (en) * | 2008-12-12 | 2010-07-16 | Solvay Pharm Bv | Spiro azepane-oxazolidinones as Kv1.3 potassium channel blockers |
WO2013052507A1 (en) | 2011-10-03 | 2013-04-11 | The Regents Of The University Of California | TREATMENT OF OBESITY AND OBESITY-RELATED DISORDERS BY PHARMACOLOGICAL TARGETING OF Kv1.3 POTASSIUM CHANNELS |
-
2012
- 2012-10-02 WO PCT/US2012/058495 patent/WO2013052507A1/en active Application Filing
- 2012-10-02 EP EP12838795.8A patent/EP2763702A4/en not_active Withdrawn
- 2012-10-02 CA CA2850357A patent/CA2850357A1/en not_active Abandoned
- 2012-10-02 KR KR1020147012093A patent/KR20140108518A/en not_active Application Discontinuation
- 2012-10-02 SG SG11201401193XA patent/SG11201401193XA/en unknown
- 2012-10-02 AU AU2012318736A patent/AU2012318736A1/en not_active Abandoned
- 2012-10-02 MX MX2014004029A patent/MX2014004029A/en unknown
- 2012-10-02 RU RU2014117558/15A patent/RU2014117558A/en not_active Application Discontinuation
- 2012-10-02 JP JP2014534641A patent/JP2014531469A/en active Pending
- 2012-10-02 US US14/347,602 patent/US20150072940A1/en not_active Abandoned
- 2012-10-02 IN IN3333CHN2014 patent/IN2014CN03333A/en unknown
- 2012-10-02 BR BR112014008065A patent/BR112014008065A2/en not_active IP Right Cessation
- 2012-10-02 CN CN201280049696.6A patent/CN103987408A/en active Pending
- 2012-10-03 TW TW101136560A patent/TW201321403A/en unknown
-
2014
- 2014-04-02 IL IL231873A patent/IL231873A0/en unknown
-
2015
- 2015-02-13 HK HK15101586.1A patent/HK1201048A1/en unknown
-
2016
- 2016-02-22 US US15/049,353 patent/US9878006B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
KR20140108518A (en) | 2014-09-11 |
CA2850357A1 (en) | 2013-04-11 |
RU2014117558A (en) | 2015-11-10 |
US20150072940A1 (en) | 2015-03-12 |
EP2763702A1 (en) | 2014-08-13 |
EP2763702A4 (en) | 2015-04-15 |
MX2014004029A (en) | 2014-08-01 |
CN103987408A (en) | 2014-08-13 |
US20170095530A1 (en) | 2017-04-06 |
BR112014008065A2 (en) | 2019-09-24 |
IL231873A0 (en) | 2014-05-28 |
TW201321403A (en) | 2013-06-01 |
JP2014531469A (en) | 2014-11-27 |
WO2013052507A1 (en) | 2013-04-11 |
AU2012318736A1 (en) | 2014-05-22 |
SG11201401193XA (en) | 2014-05-29 |
HK1201048A1 (en) | 2015-08-21 |
US9878006B2 (en) | 2018-01-30 |
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