HK1198945A1 - 定量檢測方法及其在監控慢性乙肝患者病情發展和預測治療療效中的用途 - Google Patents

定量檢測方法及其在監控慢性乙肝患者病情發展和預測治療療效中的用途

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Publication number
HK1198945A1
HK1198945A1 HK14112645.8A HK14112645A HK1198945A1 HK 1198945 A1 HK1198945 A1 HK 1198945A1 HK 14112645 A HK14112645 A HK 14112645A HK 1198945 A1 HK1198945 A1 HK 1198945A1
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HK
Hong Kong
Prior art keywords
hbc
patient
monitoring
detection method
therapeutic effect
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Application number
HK14112645.8A
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English (en)
Inventor
Quan Yuan
Liuwei Song
Wenbin Zhou
Zuxing Weng
Feihai Xu
Shengxiang Ge
Jun Zhang
Ningshao Xia
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Publication date
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Publication of HK1198945A1 publication Critical patent/HK1198945A1/zh

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    • G—PHYSICS
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    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5082—Supracellular entities, e.g. tissue, organisms
    • G01N33/5088—Supracellular entities, e.g. tissue, organisms of vertebrates
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983—Viruses
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
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    • A01K67/027—New or modified breeds of vertebrates
    • A01K67/0275—Genetically modified vertebrates, e.g. transgenic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/29—Hepatitis virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5014—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing toxicity
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/576—Immunoassay; Biospecific binding assay; Materials therefor for hepatitis
    • G01N33/5761—Hepatitis B
    • G01N33/5762—Hepatitis B core antigen
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A01K2217/052—Animals comprising random inserted nucleic acids (transgenic) inducing gain of function
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00—Animals characterised by species
    • A01K2227/40—Fish
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00—Animals characterised by purpose
    • A01K2267/03—Animal model, e.g. for test or diseases
    • A01K2267/0393—Animal model comprising a reporter system for screening tests
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    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
    • G01N2333/01—DNA viruses
    • G01N2333/02—Hepadnaviridae, e.g. hepatitis B virus
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2469/00—Immunoassays for the detection of microorganisms
    • G01N2469/20—Detection of antibodies in sample from host which are directed against antigens from microorganisms
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/56—Staging of a disease; Further complications associated with the disease

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Toxicology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Environmental Sciences (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Mycology (AREA)
  • Animal Husbandry (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Oncology (AREA)
HK14112645.8A 2012-01-21 2014-12-17 定量檢測方法及其在監控慢性乙肝患者病情發展和預測治療療效中的用途 HK1198945A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN201210019389.5A CN103217533B (zh) 2012-01-21 2012-01-21 Anti-HBc定量检测方法及其在监控慢性乙肝患者病情发展和预测治疗疗效中的用途
PCT/CN2013/070573 WO2013107355A1 (zh) 2012-01-21 2013-01-17 Anti-hbc 定量检测方法及其在监控慢性乙肝患者病情发展和预测治疗疗效中的用途

Publications (1)

Publication Number Publication Date
HK1198945A1 true HK1198945A1 (zh) 2015-06-19

Family

ID=48798632

Family Applications (1)

Application Number Title Priority Date Filing Date
HK14112645.8A HK1198945A1 (zh) 2012-01-21 2014-12-17 定量檢測方法及其在監控慢性乙肝患者病情發展和預測治療療效中的用途

Country Status (11)

Country Link
US (1) US9952217B2 (zh)
EP (1) EP2805729B1 (zh)
JP (2) JP6283319B2 (zh)
KR (1) KR101739953B1 (zh)
CN (1) CN103217533B (zh)
AU (2) AU2013211346B2 (zh)
BR (1) BR112014017877B1 (zh)
CA (1) CA2861917C (zh)
ES (1) ES2714274T3 (zh)
HK (1) HK1198945A1 (zh)
WO (1) WO2013107355A1 (zh)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104338132A (zh) * 2013-07-26 2015-02-11 复旦大学 一种病毒免疫治疗药物复合物及其用途
CN106153923B (zh) * 2016-06-21 2017-12-05 北京大学第一医院 预测谷丙转氨酶小于二倍正常上限的慢性乙型病毒性肝炎患者肝脏炎症程度的系统
CN107044977A (zh) * 2016-06-30 2017-08-15 深圳市亚辉龙生物科技股份有限公司 一种酪氨酸磷酸酶抗体化学发光免疫检测试剂盒及其制备方法
CN109991411B (zh) * 2017-12-29 2023-01-20 上海索昕生物科技有限公司 一种检测待测样本中目标抗体的免疫测定方法及其应用
CN109900896A (zh) * 2019-03-12 2019-06-18 江苏伯纳德生物科技发展有限公司 一种酶联免疫法检测试剂盒及其制备方法
WO2022252745A1 (zh) * 2021-06-02 2022-12-08 重庆医科大学 一种免疫分子病毒颗粒检测试剂盒
CN117538520B (zh) * 2024-01-05 2024-04-02 山东康华生物医疗科技股份有限公司 一种HBc-IgM抗体检测试剂盒及其制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0382962A (ja) * 1989-08-28 1991-04-08 Tosoh Corp Ｂ型肝炎ウィルスＣｏｒｅ抗原に対する抗体の検出方法
JP4292670B2 (ja) * 2000-02-08 2009-07-08 東ソー株式会社 抗ＨＢｃ抗体の免疫測定法
KR101093783B1 (ko) 2002-09-06 2011-12-19 가부시끼가이샤 센단세메이가가꾸겐큐죠 입자 형성능이 있는 ｈｂｖ 프리코어 단백질
CN1908666B (zh) * 2006-08-14 2010-05-12 武汉大学 一种检测乙肝核心抗体的双夹心法酶联免疫诊断试剂盒及应用
CN101545906A (zh) * 2008-03-25 2009-09-30 北京科美东雅生物技术有限公司 乙肝核心抗体磁微粒化学发光免疫分析测定试剂盒及其制备方法
CN101377496A (zh) * 2008-04-16 2009-03-04 北京科美东雅生物技术有限公司 一种检测甲状腺过氧化物酶自身抗体的化学发光免疫分析测定试剂盒
CN101726596A (zh) * 2009-11-04 2010-06-09 无锡中德伯尔生物技术有限公司 检测乙肝五项的荧光微球免疫层析检测卡及其制备方法

Also Published As

Publication number Publication date
BR112014017877A8 (pt) 2017-07-11
US20150118674A1 (en) 2015-04-30
JP6283319B2 (ja) 2018-02-21
BR112014017877A2 (zh) 2017-06-20
KR20140117575A (ko) 2014-10-07
AU2018200744B2 (en) 2019-08-08
KR101739953B1 (ko) 2017-05-25
CA2861917C (en) 2021-03-23
CA2861917A1 (en) 2013-07-25
EP2805729A1 (en) 2014-11-26
EP2805729A4 (en) 2015-11-11
CN103217533B (zh) 2016-01-06
AU2013211346B2 (en) 2017-11-30
AU2013211346A1 (en) 2014-08-28
US9952217B2 (en) 2018-04-24
WO2013107355A1 (zh) 2013-07-25
ES2714274T3 (es) 2019-05-28
JP2018036268A (ja) 2018-03-08
EP2805729B1 (en) 2019-01-09
AU2018200744A1 (en) 2018-02-22
CN103217533A (zh) 2013-07-24
BR112014017877B1 (pt) 2022-01-25
JP2015505371A (ja) 2015-02-19

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