HK1198514A1 - Substituted heterocyclic compounds for disease treatment - Google Patents

Substituted heterocyclic compounds for disease treatment Download PDF

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Publication number
HK1198514A1
HK1198514A1 HK14112001.6A HK14112001A HK1198514A1 HK 1198514 A1 HK1198514 A1 HK 1198514A1 HK 14112001 A HK14112001 A HK 14112001A HK 1198514 A1 HK1198514 A1 HK 1198514A1
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HK
Hong Kong
Prior art keywords
substituted heterocyclic
disorders
heterocyclic compounds
disease treatment
compositions
Prior art date
Application number
HK14112001.6A
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English (en)
Chinese (zh)
Inventor
Vladimir A. Kuksa
Mark. W. ORME
Feng Hong
Ryo Kubota
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Acucela, Inc.
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Publication date
Application filed by Acucela, Inc. filed Critical Acucela, Inc.
Publication of HK1198514A1 publication Critical patent/HK1198514A1/xx

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    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
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    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/30—Hetero atoms other than halogen
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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

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