HK1192559A1 - 3-heteroaroylamino-propionic acid derivatives and their use as pharmaceuticals 3-- - Google Patents
3-heteroaroylamino-propionic acid derivatives and their use as pharmaceuticals 3--Info
- Publication number
- HK1192559A1 HK1192559A1 HK14105865.5A HK14105865A HK1192559A1 HK 1192559 A1 HK1192559 A1 HK 1192559A1 HK 14105865 A HK14105865 A HK 14105865A HK 1192559 A1 HK1192559 A1 HK 1192559A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- heteroaroylamino
- pharmaceuticals
- propionic acid
- acid derivatives
- derivatives
- Prior art date
Links
Classifications
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- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
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- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A61K31/341—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide not condensed with another ring, e.g. ranitidine, furosemide, bufetolol, muscarine
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- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
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- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
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- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
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- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
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Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP11305971 | 2011-07-26 | ||
PCT/EP2012/064628 WO2013014204A2 (en) | 2011-07-26 | 2012-07-25 | 3-heteroaroylamino-propionic acid derivatives and their use as pharmaceuticals |
Publications (1)
Publication Number | Publication Date |
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HK1192559A1 true HK1192559A1 (en) | 2014-08-22 |
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Family Applications (2)
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HK14105865.5A HK1192559A1 (en) | 2011-07-26 | 2014-06-19 | 3-heteroaroylamino-propionic acid derivatives and their use as pharmaceuticals 3-- |
HK16113874A HK1225714A1 (zh) | 2011-07-26 | 2016-12-06 | 3-雜芳酰基氨基-丙酸衍生物及其作為藥物的用途 |
Family Applications After (1)
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HK16113874A HK1225714A1 (zh) | 2011-07-26 | 2016-12-06 | 3-雜芳酰基氨基-丙酸衍生物及其作為藥物的用途 |
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US (2) | US9353068B2 (es) |
EP (2) | EP3037417B1 (es) |
JP (2) | JP6021910B2 (es) |
KR (1) | KR20140049019A (es) |
CN (2) | CN103827097B (es) |
AU (2) | AU2012288842A1 (es) |
BR (1) | BR112014001518A2 (es) |
CA (1) | CA2841905A1 (es) |
CY (1) | CY1117397T1 (es) |
DK (1) | DK2736888T3 (es) |
ES (1) | ES2560381T3 (es) |
HK (2) | HK1192559A1 (es) |
HR (1) | HRP20160047T1 (es) |
HU (1) | HUE028418T2 (es) |
IL (2) | IL230126A (es) |
MX (1) | MX337173B (es) |
MY (1) | MY169319A (es) |
PL (1) | PL2736888T3 (es) |
PT (1) | PT2736888E (es) |
RU (1) | RU2014107000A (es) |
SI (1) | SI2736888T1 (es) |
WO (1) | WO2013014204A2 (es) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
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CN103827097B (zh) | 2011-07-26 | 2016-03-16 | 赛诺菲 | 3-杂芳酰基氨基-丙酸衍生物及其作为药物的用途 |
AU2012288843B2 (en) * | 2011-07-26 | 2016-08-04 | Sanofi | Substituted 3 - (thiazole - 4 - carbonyl) - or 3 - (thiazole - 2 - carbonyl) aminopropionic acid derivatives and their use as pharmaceuticals |
CN104603118B (zh) | 2012-05-31 | 2017-10-03 | 菲尼克斯药品股份公司 | 作为孤儿核受体RORγ调节物的经甲酰胺或磺酰胺取代的噻唑及相关衍生物 |
JO3215B1 (ar) | 2012-08-09 | 2018-03-08 | Phenex Pharmaceuticals Ag | حلقات غير متجانسة بها 5 ذرات تحتوي على النيتروجين بها استبدال بكربوكساميد أو سلفوناميد كمعدلات لمستقبل نووي غير محمي RORy |
WO2014053533A1 (en) | 2012-10-05 | 2014-04-10 | Sanofi | Use of substituted 3-heteroaroylamino-propionic acid derivatives as pharmaceuticals for prevention/treatment of atrial fibrillation |
MX2015013799A (es) | 2013-03-28 | 2016-02-16 | Sanofi Sa | Derivados de acido-biaril-propionico y su uso como productos farmaceuticos. |
AU2014243069B2 (en) | 2013-03-28 | 2017-12-21 | Sanofi | Biaryl-propionic acid derivatives and their use as pharmaceuticals |
AU2015269247B2 (en) | 2014-06-06 | 2019-10-24 | Research Triangle Institute | Apelin receptor (APJ) agonists and uses thereof |
JP2019501899A (ja) | 2015-12-09 | 2019-01-24 | リサーチ トライアングル インスティテュート | 改良アペリンレセプター(apj)アゴニストおよびその使用 |
RU2764039C2 (ru) * | 2016-10-12 | 2022-01-14 | Рисерч Трайэнгл Инститьют | Гетероциклические агонисты рецептора апелина (apj) и их применение |
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PE32799A1 (es) * | 1996-12-25 | 1999-04-09 | Agrogene Ltd | Nuevo derivado del acido aminobutirico para la proteccion de enfermedades fungosas |
PL340261A1 (en) * | 1997-10-31 | 2001-01-29 | Aventis Pharma Ltd | Substituted amilides |
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NZ509252A (en) * | 1998-08-20 | 2004-05-28 | Agouron Pharma | Non-peptide GnRH agents for treating GnRH associated diseases with pyrazole carboxamidine related structures |
DE19858191A1 (de) * | 1998-12-17 | 2000-06-21 | Aventis Cropscience Gmbh | 4-Haloalkyl-3-heterocyclylpyridine und 4-Haloalkyl-5-heterocyclyl-pyrimidine und ihre Verwendung als Repellentien |
US6462076B2 (en) | 2000-06-14 | 2002-10-08 | Hoffmann-La Roche Inc. | Beta-amino acid nitrile derivatives as cathepsin K inhibitors |
JP2002326980A (ja) * | 2001-04-27 | 2002-11-15 | Nippon Nohyaku Co Ltd | ジアミド誘導体及び農園芸用薬剤並びにその使用方法 |
BR0214642A (pt) * | 2001-12-04 | 2004-11-03 | Hoffmann La Roche | Compostos, métodos para a preparação de um composto, composições farmacêuticas que compreendem o mesmo e método para o tratamento e/ou prevenção de enfermidades que estão associadas com protéases de cisteìna e utilização desses compostos |
US20040072802A1 (en) | 2002-10-09 | 2004-04-15 | Jingwu Duan | Beta-amino acid derivatives as inhibitors of matrix metalloproteases and TNF-alpha |
EP1581523B1 (en) | 2002-12-23 | 2009-09-30 | Sanofi-Aventis Deutschland GmbH | Pyrazole-derivatives as factor xa inhibitors |
WO2004083163A1 (ja) * | 2003-03-17 | 2004-09-30 | Ube Industries, Ltd. | 3-アミノ-3-アリールプロピオン酸n-アルキルエステル及びその製造方法並びに光学活性3-アミノ-3-アリールプロピオン酸及びその対掌エステルの製造方法 |
EP1493740A1 (fr) | 2003-07-03 | 2005-01-05 | Warner-Lambert Company LLC | Dérivés de 5-fluoro-thiophene, leur procédé de preparation, les compositions pharmaceutiques les contenant et leur utilisation comme inhibiteurs de métalloprotéinases |
EP1493739A1 (fr) | 2003-07-03 | 2005-01-05 | Warner-Lambert Company LLC | Dérivés thiophényliques d'aminoacides, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent |
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JP2005145839A (ja) | 2003-11-12 | 2005-06-09 | Japan Science & Technology Agency | 新規なカテプシンa阻害剤 |
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CN103827097B (zh) | 2011-07-26 | 2016-03-16 | 赛诺菲 | 3-杂芳酰基氨基-丙酸衍生物及其作为药物的用途 |
-
2012
- 2012-07-25 CN CN201280046863.1A patent/CN103827097B/zh not_active Expired - Fee Related
- 2012-07-25 DK DK12738473.3T patent/DK2736888T3/da active
- 2012-07-25 PT PT127384733T patent/PT2736888E/pt unknown
- 2012-07-25 EP EP15190731.8A patent/EP3037417B1/en not_active Not-in-force
- 2012-07-25 AU AU2012288842A patent/AU2012288842A1/en not_active Abandoned
- 2012-07-25 WO PCT/EP2012/064628 patent/WO2013014204A2/en active Application Filing
- 2012-07-25 RU RU2014107000/04A patent/RU2014107000A/ru not_active Application Discontinuation
- 2012-07-25 KR KR1020147004756A patent/KR20140049019A/ko not_active Application Discontinuation
- 2012-07-25 ES ES12738473.3T patent/ES2560381T3/es active Active
- 2012-07-25 SI SI201230439T patent/SI2736888T1/sl unknown
- 2012-07-25 PL PL12738473T patent/PL2736888T3/pl unknown
- 2012-07-25 MY MYPI2013004643A patent/MY169319A/en unknown
- 2012-07-25 BR BR112014001518A patent/BR112014001518A2/pt not_active IP Right Cessation
- 2012-07-25 MX MX2014000598A patent/MX337173B/es active IP Right Grant
- 2012-07-25 EP EP12738473.3A patent/EP2736888B1/en not_active Not-in-force
- 2012-07-25 CN CN201511021647.3A patent/CN105646362B/zh not_active Expired - Fee Related
- 2012-07-25 JP JP2014522086A patent/JP6021910B2/ja not_active Expired - Fee Related
- 2012-07-25 CA CA2841905A patent/CA2841905A1/en not_active Abandoned
- 2012-07-25 HU HUE12738473A patent/HUE028418T2/en unknown
- 2012-07-26 US US13/559,401 patent/US9353068B2/en not_active Expired - Fee Related
-
2013
- 2013-12-23 IL IL230126A patent/IL230126A/en not_active IP Right Cessation
-
2014
- 2014-06-19 HK HK14105865.5A patent/HK1192559A1/xx not_active IP Right Cessation
-
2016
- 2016-01-15 HR HRP20160047TT patent/HRP20160047T1/hr unknown
- 2016-02-03 CY CY20161100093T patent/CY1117397T1/el unknown
- 2016-04-27 US US15/140,350 patent/US9751858B2/en not_active Expired - Fee Related
- 2016-09-30 JP JP2016192793A patent/JP6360534B2/ja not_active Expired - Fee Related
- 2016-12-06 HK HK16113874A patent/HK1225714A1/zh unknown
-
2017
- 2017-01-31 IL IL250370A patent/IL250370A0/en unknown
- 2017-06-02 AU AU2017203739A patent/AU2017203739A1/en not_active Abandoned
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Legal Events
Date | Code | Title | Description |
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PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20190731 |