HK1180677A1 - 異喹啉衍生物或其鹽的新製造方法 - Google Patents
異喹啉衍生物或其鹽的新製造方法Info
- Publication number
- HK1180677A1 HK1180677A1 HK13107786.8A HK13107786A HK1180677A1 HK 1180677 A1 HK1180677 A1 HK 1180677A1 HK 13107786 A HK13107786 A HK 13107786A HK 1180677 A1 HK1180677 A1 HK 1180677A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- salts
- production method
- novel production
- isoquinoline derivatives
- isoquinoline
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/08—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 not condensed with other rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2010189392 | 2010-08-26 | ||
| PCT/JP2011/069187 WO2012026529A1 (ja) | 2010-08-26 | 2011-08-25 | イソキノリン誘導体又はその塩の新規製造方法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1180677A1 true HK1180677A1 (zh) | 2013-10-25 |
Family
ID=45723520
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK13107786.8A HK1180677A1 (zh) | 2010-08-26 | 2013-07-03 | 異喹啉衍生物或其鹽的新製造方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US9045460B2 (zh) |
| EP (2) | EP2610252A4 (zh) |
| JP (2) | JP5858917B2 (zh) |
| CN (2) | CN103068818B (zh) |
| HK (1) | HK1180677A1 (zh) |
| WO (1) | WO2012026529A1 (zh) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111233770B (zh) * | 2020-02-28 | 2022-12-27 | 南通大学 | 一种手性吡唑衍生物及其合成方法 |
| CN111909088B (zh) * | 2020-08-04 | 2022-03-01 | 浙江工业大学 | 利用BTC/Ph3PO氯代体系制备异喹啉类盐酸盐中间体及Rho激酶抑制剂的方法 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5464192A (en) * | 1978-08-03 | 1979-05-23 | Daido Maruta Finishing | Printing method |
| JPS61227581A (ja) * | 1985-04-02 | 1986-10-09 | Asahi Chem Ind Co Ltd | 血管拡張剤 |
| US4678783B1 (en) | 1983-11-04 | 1995-04-04 | Asahi Chemical Ind | Substituted isoquinolinesulfonyl compounds |
| JPS63120182A (ja) * | 1986-09-10 | 1988-05-24 | バスフ オーストラリア リミテッド | 織物繊維の着色方法 |
| JP2564439B2 (ja) * | 1991-11-12 | 1996-12-18 | 防衛庁技術研究本部長 | カムフラージュ用布帛 |
| JP2990073B2 (ja) * | 1995-07-28 | 1999-12-13 | 大日本製薬株式会社 | （ｒ）−１−エチル−４−メチルヘキサヒドロ−１ｈ−１，４−ジアゼピン誘導体及びそれを含有する医薬 |
| NZ312799A (en) | 1995-07-28 | 1999-04-29 | Dainippon Pharmaceutical Co | (r)-5-bromo--(1-ethyl-4-methylhexahydro-1h-1,4-diazepin-6-yl)-2-met hoxy-6-methylamino-3-pyridinecarboxamide, process for preparation thereof |
| KR19990082174A (ko) | 1996-02-02 | 1999-11-25 | 니뽄 신야쿠 가부시키가이샤 | 이소퀴놀린 유도체 및 의약 |
| JP4316794B2 (ja) * | 1997-10-22 | 2009-08-19 | 株式会社デ・ウエスタン・セラピテクス研究所 | イソキノリン誘導体及び医薬 |
| JPH11171885A (ja) | 1997-12-12 | 1999-06-29 | Asahi Chem Ind Co Ltd | １−（５−イソキノリンスルホニル）ホモピペラジンの親水性溶媒を用いる製造法 |
| US6452001B2 (en) | 2000-05-25 | 2002-09-17 | Hoffmann-La Roche Inc. | Diazapane derivatives useful as antagonists of neurokinin 1 receptor and methods for their formation |
| TW200621257A (en) | 2004-10-20 | 2006-07-01 | Astellas Pharma Inc | Pyrimidine derivative fused with nonaromatic ring |
| MY139797A (en) | 2004-11-29 | 2009-10-30 | Kowa Co | (s)-(-)-1-(4-fluoroisoquinolin-5-yl)sulfonyl-2-methyl-1, 4-homopiperazine hydrochloride dihydrate |
| JP2006290827A (ja) | 2005-04-13 | 2006-10-26 | Kowa Co | 緑内障予防又は治療剤 |
| JP2006348028A (ja) | 2005-05-19 | 2006-12-28 | Kowa Co | 緑内障予防又は治療剤 |
| JP2007238458A (ja) * | 2006-03-06 | 2007-09-20 | D Western Therapeutics Institute Inc | 新規なイソキノリン誘導体及びこれを含有する医薬 |
| US20080064681A1 (en) * | 2006-09-11 | 2008-03-13 | Hiroyoshi Hidaka | Therapeutic agent for treating glaucoma |
| EP1918285A1 (en) | 2006-11-03 | 2008-05-07 | Merck Sante | Diazepane-acetamide derivatives as selective 11beta-HSD1 inhibitors |
-
2011
- 2011-08-25 EP EP11819992.6A patent/EP2610252A4/en not_active Withdrawn
- 2011-08-25 CN CN201180040996.3A patent/CN103068818B/zh active Active
- 2011-08-25 CN CN201410161940.9A patent/CN103951624B/zh not_active Expired - Fee Related
- 2011-08-25 US US13/816,534 patent/US9045460B2/en active Active
- 2011-08-25 JP JP2012530708A patent/JP5858917B2/ja active Active
- 2011-08-25 EP EP14002011.6A patent/EP2818463A1/en not_active Withdrawn
- 2011-08-25 WO PCT/JP2011/069187 patent/WO2012026529A1/ja active Application Filing
-
2013
- 2013-07-03 HK HK13107786.8A patent/HK1180677A1/zh unknown
-
2014
- 2014-07-25 JP JP2014151680A patent/JP5977289B2/ja active Active
- 2014-12-05 US US14/561,258 patent/US9540344B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| JP5977289B2 (ja) | 2016-08-24 |
| CN103068818A (zh) | 2013-04-24 |
| CN103951624B (zh) | 2019-04-16 |
| US9045460B2 (en) | 2015-06-02 |
| US20130144054A1 (en) | 2013-06-06 |
| CN103068818B (zh) | 2014-11-19 |
| JP2014240399A (ja) | 2014-12-25 |
| WO2012026529A1 (ja) | 2012-03-01 |
| JP5858917B2 (ja) | 2016-02-10 |
| CN103951624A (zh) | 2014-07-30 |
| EP2818463A1 (en) | 2014-12-31 |
| US20150087824A1 (en) | 2015-03-26 |
| EP2610252A4 (en) | 2013-09-04 |
| JPWO2012026529A1 (ja) | 2013-10-28 |
| EP2610252A1 (en) | 2013-07-03 |
| US9540344B2 (en) | 2017-01-10 |
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