HK1177732A1 - 阿戈美拉汀溴化氫水合物及其製備方法 - Google Patents

阿戈美拉汀溴化氫水合物及其製備方法

Info

Publication number
HK1177732A1
HK1177732A1 HK13104895.3A HK13104895A HK1177732A1 HK 1177732 A1 HK1177732 A1 HK 1177732A1 HK 13104895 A HK13104895 A HK 13104895A HK 1177732 A1 HK1177732 A1 HK 1177732A1
Authority
HK
Hong Kong
Prior art keywords
preparation
hydrobromide hydrate
agomelatine hydrobromide
agomelatine
hydrate
Prior art date
Application number
HK13104895.3A
Other languages
English (en)
Inventor
Hanbin Shan
Zhedong Yuan
Xueyan Zhu
Peng Zhang
Hongjuan Pan
Xiong Yu
Original Assignee
Servier Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=44599557&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1177732(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Servier Lab filed Critical Servier Lab
Publication of HK1177732A1 publication Critical patent/HK1177732A1/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/16—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
    • C07C233/17—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
    • C07C233/18—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/12—Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups
HK13104895.3A 2010-03-17 2013-04-23 阿戈美拉汀溴化氫水合物及其製備方法 HK1177732A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN2010101262639A CN102190595A (zh) 2010-03-17 2010-03-17 阿戈美拉汀溴化氢水合物及其制备方法
PCT/CN2011/071912 WO2011113363A1 (en) 2010-03-17 2011-03-17 Agomelatine hydrobromide hydrate and preparation thereof

Publications (1)

Publication Number Publication Date
HK1177732A1 true HK1177732A1 (zh) 2013-08-30

Family

ID=44599557

Family Applications (1)

Application Number Title Priority Date Filing Date
HK13104895.3A HK1177732A1 (zh) 2010-03-17 2013-04-23 阿戈美拉汀溴化氫水合物及其製備方法

Country Status (39)

Country Link
US (1) US8729132B2 (zh)
EP (1) EP2547650B1 (zh)
JP (1) JP5634533B2 (zh)
KR (1) KR101406736B1 (zh)
CN (2) CN102190595A (zh)
AP (1) AP3199A (zh)
AU (1) AU2011229619B2 (zh)
BR (1) BR112012023173B1 (zh)
CA (1) CA2792430C (zh)
CL (1) CL2012002541A1 (zh)
CR (1) CR20120461A (zh)
CU (1) CU20120136A7 (zh)
CY (1) CY1117134T1 (zh)
DK (1) DK2547650T3 (zh)
EA (1) EA022066B1 (zh)
EC (1) ECSP12012156A (zh)
ES (1) ES2572427T3 (zh)
GE (1) GEP20156232B (zh)
GT (1) GT201200260A (zh)
HK (1) HK1177732A1 (zh)
HN (1) HN2012001923A (zh)
HR (1) HRP20151343T1 (zh)
HU (1) HUE026673T2 (zh)
IL (1) IL221783A (zh)
MA (1) MA34054B1 (zh)
ME (1) ME02309B (zh)
MX (1) MX2012010594A (zh)
MY (1) MY160337A (zh)
NI (1) NI201200141A (zh)
NZ (1) NZ602451A (zh)
PE (1) PE20130014A1 (zh)
PL (1) PL2547650T3 (zh)
PT (1) PT2547650E (zh)
RS (1) RS54449B1 (zh)
SG (1) SG183869A1 (zh)
SI (1) SI2547650T1 (zh)
TN (1) TN2012000436A1 (zh)
UA (1) UA105424C2 (zh)
WO (1) WO2011113363A1 (zh)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2978916B1 (fr) 2011-08-10 2013-07-26 Servier Lab Composition pharmaceutique solide pour administration buccale d'agomelatine
WO2013170738A1 (zh) * 2012-05-14 2013-11-21 上海右手医药科技开发有限公司 阿戈美拉汀酸根复合物及其制备方法和用途
CN102718675B (zh) * 2012-06-07 2015-03-25 上海右手医药科技开发有限公司 阿戈美拉汀甲磺酸复合物及其制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2658818B1 (fr) * 1990-02-27 1993-12-31 Adir Cie Nouveaux derives a structure naphtalenique, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
PL366150A1 (en) * 2000-10-30 2005-01-24 Teva Pharmaceutical Industries Ltd. Novel crystal and solvate forms of ondansetron hydrochloride and processes for their preparation
FR2890562B1 (fr) * 2005-09-09 2012-10-12 Servier Lab Utilisation de l'agomelatine pour l'obtention de medicaments destines au traitement des troubles du sommeil chez le patient deprime
FR2899472B1 (fr) * 2006-04-07 2008-09-12 Servier Lab Utilisation de l'agomelatine pour l'obtention de medicaments destines au traitement du trouble anxiete generalisee
CN101481321B (zh) * 2009-02-27 2012-04-18 上海医药工业研究院 阿戈美拉汀卤化氢复合物及其制备方法
CN101585779B (zh) * 2009-03-10 2014-04-02 上海医药工业研究院 阿戈美拉汀的晶型vi及其制备方法和应用

Also Published As

Publication number Publication date
MY160337A (en) 2017-02-28
CY1117134T1 (el) 2017-04-05
AP3199A (en) 2015-03-31
CN102892749B (zh) 2014-11-05
DK2547650T3 (en) 2016-02-15
CU20120136A7 (es) 2012-12-17
CN102892749A (zh) 2013-01-23
PT2547650E (pt) 2015-11-30
IL221783A (en) 2017-11-30
GEP20156232B (en) 2015-01-26
JP5634533B2 (ja) 2014-12-03
NZ602451A (en) 2014-10-31
PE20130014A1 (es) 2013-01-26
PL2547650T3 (pl) 2016-06-30
EA201201293A1 (ru) 2013-04-30
RS54449B1 (en) 2016-06-30
BR112012023173B1 (pt) 2021-08-24
SI2547650T1 (sl) 2016-02-29
UA105424C2 (uk) 2014-05-12
MX2012010594A (es) 2012-10-03
EA022066B1 (ru) 2015-10-30
NI201200141A (es) 2012-11-09
EP2547650B1 (en) 2015-11-04
CR20120461A (es) 2012-11-29
MA34054B1 (fr) 2013-03-05
CA2792430C (en) 2015-12-08
CA2792430A1 (en) 2011-09-22
BR112012023173A2 (pt) 2016-05-17
ES2572427T3 (es) 2016-05-31
AU2011229619B2 (en) 2014-05-22
HUE026673T2 (en) 2016-07-28
GT201200260A (es) 2013-11-18
WO2011113363A1 (en) 2011-09-22
ECSP12012156A (es) 2012-12-28
CL2012002541A1 (es) 2013-01-11
EP2547650A1 (en) 2013-01-23
ME02309B (me) 2016-06-20
KR101406736B1 (ko) 2014-06-12
SG183869A1 (en) 2012-10-30
AP2012006493A0 (en) 2012-10-31
KR20120128713A (ko) 2012-11-27
AU2011229619A1 (en) 2012-09-27
TN2012000436A1 (en) 2014-01-30
HRP20151343T1 (hr) 2016-01-01
JP2013522242A (ja) 2013-06-13
CN102190595A (zh) 2011-09-21
EP2547650A4 (en) 2013-09-18
HN2012001923A (es) 2015-09-14
US20130012592A1 (en) 2013-01-10
US8729132B2 (en) 2014-05-20

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20230321