HK1171760A1 - 含有 -縮醛乙酰丙酸酯基團 單體及其在 微陣列中的應用 - Google Patents
含有 -縮醛乙酰丙酸酯基團 單體及其在 微陣列中的應用Info
- Publication number
- HK1171760A1 HK1171760A1 HK12112648.7A HK12112648A HK1171760A1 HK 1171760 A1 HK1171760 A1 HK 1171760A1 HK 12112648 A HK12112648 A HK 12112648A HK 1171760 A1 HK1171760 A1 HK 1171760A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- rna
- levulinyl ester
- acetal levulinyl
- microarrays
- monomers containing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
- C07H21/02—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with ribosyl as saccharide radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
- C07H19/067—Pyrimidine radicals with ribosyl as the saccharide radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
- C07H19/167—Purine radicals with ribosyl as the saccharide radical
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
- C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Saccharide Compounds (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US9452508P | 2008-09-05 | 2008-09-05 | |
| US18156209P | 2009-05-27 | 2009-05-27 | |
| PCT/CA2009/001244 WO2010025566A1 (en) | 2008-09-05 | 2009-09-04 | Rna monomers containing o-acetal levulinyl ester groups and their use in rna microarrays |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1171760A1 true HK1171760A1 (zh) | 2013-04-05 |
Family
ID=41796692
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK12112648.7A HK1171760A1 (zh) | 2008-09-05 | 2012-12-07 | 含有 -縮醛乙酰丙酸酯基團 單體及其在 微陣列中的應用 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US9249175B2 (zh) |
| EP (1) | EP2334692B1 (zh) |
| CN (1) | CN102639552B (zh) |
| AU (1) | AU2009290102A1 (zh) |
| CA (1) | CA2772434C (zh) |
| HK (1) | HK1171760A1 (zh) |
| WO (1) | WO2010025566A1 (zh) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20140255471A1 (en) | 2013-03-11 | 2014-09-11 | Wake Forest University Health Sciences | Method of treating brain tumors |
| DK3030682T3 (da) | 2013-08-05 | 2020-09-14 | Twist Bioscience Corp | De novo synthesized gene libraries |
| WO2016126987A1 (en) | 2015-02-04 | 2016-08-11 | Twist Bioscience Corporation | Compositions and methods for synthetic gene assembly |
| WO2016126882A1 (en) | 2015-02-04 | 2016-08-11 | Twist Bioscience Corporation | Methods and devices for de novo oligonucleic acid assembly |
| US9981239B2 (en) | 2015-04-21 | 2018-05-29 | Twist Bioscience Corporation | Devices and methods for oligonucleic acid library synthesis |
| WO2016170179A1 (en) | 2015-04-24 | 2016-10-27 | Qiagen Gmbh | Method for immobilizing a nucleic acid molecule on solid support |
| US11085073B2 (en) | 2015-04-24 | 2021-08-10 | Qiagen Gmbh | Method for immobilizing a nucleic acid molecule on a solid support |
| IL258164B (en) | 2015-09-18 | 2022-09-01 | Twist Bioscience Corp | Methods to regulate the activity of proteins and cells and a method for the production of nucleic acids |
| US11512347B2 (en) | 2015-09-22 | 2022-11-29 | Twist Bioscience Corporation | Flexible substrates for nucleic acid synthesis |
| EP3384077A4 (en) | 2015-12-01 | 2019-05-08 | Twist Bioscience Corporation | FUNCTIONALIZED SURFACES AND THEIR PREPARATION |
| JP6854340B2 (ja) | 2016-08-22 | 2021-04-07 | ツイスト バイオサイエンス コーポレーション | デノボ合成された核酸ライブラリ |
| US10417457B2 (en) | 2016-09-21 | 2019-09-17 | Twist Bioscience Corporation | Nucleic acid based data storage |
| US10907274B2 (en) | 2016-12-16 | 2021-02-02 | Twist Bioscience Corporation | Variant libraries of the immunological synapse and synthesis thereof |
| CN118116478A (zh) | 2017-02-22 | 2024-05-31 | 特韦斯特生物科学公司 | 基于核酸的数据存储 |
| CA3056388A1 (en) | 2017-03-15 | 2018-09-20 | Twist Bioscience Corporation | Variant libraries of the immunological synapse and synthesis thereof |
| WO2018231872A1 (en) | 2017-06-12 | 2018-12-20 | Twist Bioscience Corporation | Methods for seamless nucleic acid assembly |
| WO2018231864A1 (en) | 2017-06-12 | 2018-12-20 | Twist Bioscience Corporation | Methods for seamless nucleic acid assembly |
| US11407837B2 (en) | 2017-09-11 | 2022-08-09 | Twist Bioscience Corporation | GPCR binding proteins and synthesis thereof |
| CA3079613A1 (en) | 2017-10-20 | 2019-04-25 | Twist Bioscience Corporation | Heated nanowells for polynucleotide synthesis |
| US11971414B2 (en) | 2017-12-22 | 2024-04-30 | Wisconsin Alumni Research Foundation | Nanoengineered surfaces for cancer biomarker capture |
| WO2019136175A1 (en) | 2018-01-04 | 2019-07-11 | Twist Bioscience Corporation | Dna-based digital information storage |
| AU2019270243A1 (en) | 2018-05-18 | 2021-01-07 | Twist Bioscience Corporation | Polynucleotides, reagents, and methods for nucleic acid hybridization |
| WO2020176680A1 (en) | 2019-02-26 | 2020-09-03 | Twist Bioscience Corporation | Variant nucleic acid libraries for antibody optimization |
| CN113766930A (zh) | 2019-02-26 | 2021-12-07 | 特韦斯特生物科学公司 | Glp1受体的变异核酸文库 |
| EP3956447A1 (en) * | 2019-04-18 | 2022-02-23 | ProQR Therapeutics II B.V. | Antisense oligonucleotides for the treatment of usher syndrome |
| AU2020298294A1 (en) | 2019-06-21 | 2022-02-17 | Twist Bioscience Corporation | Barcode-based nucleic acid sequence assembly |
| US12091777B2 (en) | 2019-09-23 | 2024-09-17 | Twist Bioscience Corporation | Variant nucleic acid libraries for CRTH2 |
| CN110922441B (zh) * | 2019-11-21 | 2023-07-11 | 佛山市艾达思精密仪器有限公司 | 光定向微阵列dna合成的链接基质物和合成方法 |
| CN114685560B (zh) * | 2020-12-31 | 2024-05-14 | 沈阳药科大学 | 含哌啶骨架亚磷酰胺单体及寡聚核苷酸的合成和应用 |
| CN118317970A (zh) | 2021-11-29 | 2024-07-09 | 兆维生物科技公司 | 2'乙酰基-酯保护的核苷的合成 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1992007065A1 (en) * | 1990-10-12 | 1992-04-30 | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. | Modified ribozymes |
| EP0991777A1 (en) * | 1997-06-18 | 2000-04-12 | Ulrich J. Krull | Nucleic acid biosensor diagnostics |
| CN1249418C (zh) * | 1997-09-11 | 2006-04-05 | 生物风险公司 | 一种生产目标物质的高密度阵列的方法及高密度阵列 |
| CN100588759C (zh) * | 2007-03-20 | 2010-02-10 | 苏州纳米技术与纳米仿生研究所 | 原位合成制备化合物芯片的方法、制备载体及发光基底 |
-
2009
- 2009-09-04 CN CN200980144324.XA patent/CN102639552B/zh active Active
- 2009-09-04 EP EP09810972.1A patent/EP2334692B1/en not_active Not-in-force
- 2009-09-04 CA CA2772434A patent/CA2772434C/en active Active
- 2009-09-04 WO PCT/CA2009/001244 patent/WO2010025566A1/en active Application Filing
- 2009-09-04 AU AU2009290102A patent/AU2009290102A1/en not_active Abandoned
- 2009-09-04 US US13/061,022 patent/US9249175B2/en active Active
-
2012
- 2012-12-07 HK HK12112648.7A patent/HK1171760A1/zh unknown
-
2015
- 2015-12-29 US US14/983,504 patent/US10287313B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| CA2772434A1 (en) | 2010-03-11 |
| CA2772434C (en) | 2017-11-21 |
| US9249175B2 (en) | 2016-02-02 |
| US20120178638A1 (en) | 2012-07-12 |
| CN102639552A (zh) | 2012-08-15 |
| AU2009290102A1 (en) | 2010-03-11 |
| US10287313B2 (en) | 2019-05-14 |
| EP2334692A4 (en) | 2014-12-03 |
| EP2334692A1 (en) | 2011-06-22 |
| US20160340382A1 (en) | 2016-11-24 |
| CN102639552B (zh) | 2016-05-25 |
| EP2334692B1 (en) | 2016-04-13 |
| WO2010025566A1 (en) | 2010-03-11 |
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