HK1169404A1 - Intermediates and processes for the preparation of 4- (acetylamino)) -3- [(4-chloro-phenyl) thio]-2-methyl-1h-indole-1-acetic acid - Google Patents
Intermediates and processes for the preparation of 4- (acetylamino)) -3- [(4-chloro-phenyl) thio]-2-methyl-1h-indole-1-acetic acidInfo
- Publication number
- HK1169404A1 HK1169404A1 HK12110140.4A HK12110140A HK1169404A1 HK 1169404 A1 HK1169404 A1 HK 1169404A1 HK 12110140 A HK12110140 A HK 12110140A HK 1169404 A1 HK1169404 A1 HK 1169404A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- acetylamino
- indole
- thio
- intermediates
- chloro
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/40—Nitrogen atoms, not forming part of a nitro radical, e.g. isatin semicarbazone
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/32—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US22316309P | 2009-07-06 | 2009-07-06 | |
| PCT/GB2010/051100 WO2011004182A1 (en) | 2009-07-06 | 2010-07-05 | Intermediates and processes for the preparation of 4- (acetylamino) ) -3- [ (4-chloro-phenyl) thio] -2-methyl-1h-indole-1-acetic acid |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1169404A1 true HK1169404A1 (en) | 2013-01-25 |
Family
ID=42780497
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK12110140.4A HK1169404A1 (en) | 2009-07-06 | 2012-10-13 | Intermediates and processes for the preparation of 4- (acetylamino)) -3- [(4-chloro-phenyl) thio]-2-methyl-1h-indole-1-acetic acid |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US8227622B2 (xx) |
| EP (1) | EP2451780B1 (xx) |
| JP (1) | JP5675800B2 (xx) |
| KR (1) | KR101752932B1 (xx) |
| CN (1) | CN102482214B (xx) |
| AR (1) | AR077457A1 (xx) |
| AU (1) | AU2010270050B9 (xx) |
| BR (1) | BR112012000353B1 (xx) |
| CA (1) | CA2767132C (xx) |
| ES (1) | ES2426679T3 (xx) |
| HK (1) | HK1169404A1 (xx) |
| IL (1) | IL217088A0 (xx) |
| MX (1) | MX2012000229A (xx) |
| RU (1) | RU2551852C2 (xx) |
| SG (1) | SG177286A1 (xx) |
| TW (1) | TW201118067A (xx) |
| WO (1) | WO2011004182A1 (xx) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104817544B (zh) * | 2015-03-23 | 2017-05-10 | 三峡大学 | 一种四氢吲哚‑4‑酮肟类药物，制备方法及其应用 |
| JP6452584B2 (ja) * | 2015-09-30 | 2019-01-16 | 富士フイルム株式会社 | 芳香族化合物の製造方法 |
| JP6472419B2 (ja) * | 2015-09-30 | 2019-02-20 | 富士フイルム株式会社 | 芳香族化合物の製造方法 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6916841B2 (en) | 1998-02-25 | 2005-07-12 | Genetics Institute, Llc | Inhibitors of phospholipase enzymes |
| AU7962200A (en) | 1999-10-29 | 2001-05-14 | Wakunaga Pharmaceutical Co., Ltd | Novel indole derivatives and drugs containing the same as the active ingredient |
| TWI317634B (en) | 2001-12-13 | 2009-12-01 | Nat Health Research Institutes | Aroyl indoles compounds |
| TW200307542A (en) | 2002-05-30 | 2003-12-16 | Astrazeneca Ab | Novel compounds |
| SE0202241D0 (sv) | 2002-07-17 | 2002-07-17 | Astrazeneca Ab | Novel Compounds |
| SE0301569D0 (sv) | 2003-05-27 | 2003-05-27 | Astrazeneca Ab | Novel compounds |
| SE0302232D0 (sv) | 2003-08-18 | 2003-08-18 | Astrazeneca Ab | Novel Compounds |
| GB0428100D0 (en) | 2004-12-23 | 2005-01-26 | Astrazeneca Ab | Chemical processes & intermediates |
| GB0500604D0 (en) * | 2005-01-13 | 2005-02-16 | Astrazeneca Ab | Novel process |
| GB0500643D0 (en) | 2005-01-13 | 2005-02-23 | Renovo Ltd | Medicaments |
| GB2422831A (en) | 2005-02-04 | 2006-08-09 | Oxagen Ltd | Pyrrolopyridines and their use in the treatment of diseases mediated by PGD2 at the CRTH2 receptor |
| JP2009538289A (ja) | 2006-05-26 | 2009-11-05 | アストラゼネカ・アクチエボラーグ | ビアリールまたはヘテロアリール置換インドール |
| RU2008152763A (ru) | 2006-06-08 | 2010-07-20 | Ньюроки А/С (Dk) | Применение агонистов каннабиноидного рецептора в качестве индуцирующих гипотермию лекарственных средств для лечения ишемии |
| KR20090023645A (ko) | 2006-06-28 | 2009-03-05 | 사노피-아벤티스 | 신규한 ｃｘｃｒ2 억제제 |
-
2010
- 2010-07-05 BR BR112012000353-4A patent/BR112012000353B1/pt not_active IP Right Cessation
- 2010-07-05 ES ES10752114T patent/ES2426679T3/es active Active
- 2010-07-05 TW TW099122052A patent/TW201118067A/zh unknown
- 2010-07-05 RU RU2012103466/04A patent/RU2551852C2/ru active
- 2010-07-05 WO PCT/GB2010/051100 patent/WO2011004182A1/en active Application Filing
- 2010-07-05 KR KR1020127000311A patent/KR101752932B1/ko active IP Right Grant
- 2010-07-05 EP EP10752114.8A patent/EP2451780B1/en not_active Not-in-force
- 2010-07-05 CA CA2767132A patent/CA2767132C/en not_active Expired - Fee Related
- 2010-07-05 JP JP2012519061A patent/JP5675800B2/ja not_active Expired - Fee Related
- 2010-07-05 AU AU2010270050A patent/AU2010270050B9/en not_active Ceased
- 2010-07-05 CN CN201080039492.5A patent/CN102482214B/zh not_active Expired - Fee Related
- 2010-07-05 SG SG2011094166A patent/SG177286A1/en unknown
- 2010-07-05 MX MX2012000229A patent/MX2012000229A/es active IP Right Grant
- 2010-07-06 US US12/830,577 patent/US8227622B2/en active Active
- 2010-07-06 AR ARP100102423A patent/AR077457A1/es unknown
-
2011
- 2011-12-19 IL IL217088A patent/IL217088A0/en unknown
-
2012
- 2012-10-13 HK HK12110140.4A patent/HK1169404A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| RU2551852C2 (ru) | 2015-05-27 |
| TW201118067A (en) | 2011-06-01 |
| SG177286A1 (en) | 2012-02-28 |
| KR101752932B1 (ko) | 2017-07-03 |
| KR20120030525A (ko) | 2012-03-28 |
| BR112012000353B1 (pt) | 2020-06-02 |
| AU2010270050A1 (en) | 2012-02-02 |
| CA2767132A1 (en) | 2011-01-13 |
| ES2426679T3 (es) | 2013-10-24 |
| CA2767132C (en) | 2017-06-20 |
| WO2011004182A1 (en) | 2011-01-13 |
| BR112012000353A2 (pt) | 2017-06-13 |
| US20110046394A1 (en) | 2011-02-24 |
| RU2012103466A (ru) | 2013-08-20 |
| JP5675800B2 (ja) | 2015-02-25 |
| CN102482214A (zh) | 2012-05-30 |
| IL217088A0 (en) | 2012-02-29 |
| AR077457A1 (es) | 2011-08-31 |
| AU2010270050B2 (en) | 2013-06-06 |
| US8227622B2 (en) | 2012-07-24 |
| AU2010270050B9 (en) | 2013-06-27 |
| CN102482214B (zh) | 2014-08-27 |
| EP2451780A1 (en) | 2012-05-16 |
| MX2012000229A (es) | 2012-01-25 |
| JP2012532186A (ja) | 2012-12-13 |
| EP2451780B1 (en) | 2013-06-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20210705 |