HK1167859A1 - Compounds with two fused bicyclic heteroaryl moieties as modulators of leukotriene a4 hydrolase - Google Patents

Compounds with two fused bicyclic heteroaryl moieties as modulators of leukotriene a4 hydrolase

Info

Publication number
HK1167859A1
HK1167859A1 HK12108500.2A HK12108500A HK1167859A1 HK 1167859 A1 HK1167859 A1 HK 1167859A1 HK 12108500 A HK12108500 A HK 12108500A HK 1167859 A1 HK1167859 A1 HK 1167859A1
Authority
HK
Hong Kong
Prior art keywords
leukotriene
hydrolase
modulators
compounds
bicyclic heteroaryl
Prior art date
Application number
HK12108500.2A
Other languages
English (en)
Inventor
Genesis M Bacani
Christa C Chrovian
Wendy Eccles
Anne M Fourie
Laurent Gomez
Cheryl A Grice
Aaron M Kearney
Adrienne Landry-Bayle
Alice Lee-Dutra
Alejandro Santillan
Virginia M Tanis
John J M Wiener
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of HK1167859A1 publication Critical patent/HK1167859A1/xx

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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/428—Thiazoles condensed with carbocyclic rings
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    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
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    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
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    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
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    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
HK12108500.2A 2009-05-14 2012-08-30 Compounds with two fused bicyclic heteroaryl moieties as modulators of leukotriene a4 hydrolase HK1167859A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US17816909P 2009-05-14 2009-05-14
US25277409P 2009-10-19 2009-10-19
PCT/US2010/034597 WO2010132599A1 (en) 2009-05-14 2010-05-12 Compounds with two fused bicyclic heteroaryl moieties as modulators of leukotriene a4 hydrolase

Publications (1)

Publication Number Publication Date
HK1167859A1 true HK1167859A1 (en) 2012-12-14

Family

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HK12108500.2A HK1167859A1 (en) 2009-05-14 2012-08-30 Compounds with two fused bicyclic heteroaryl moieties as modulators of leukotriene a4 hydrolase

Country Status (15)

Country Link
US (1) US8399465B2 (xx)
EP (1) EP2430019B1 (xx)
JP (1) JP5746685B2 (xx)
KR (1) KR101727650B1 (xx)
CN (1) CN102459251B (xx)
AR (1) AR080539A1 (xx)
AU (1) AU2010249041B2 (xx)
BR (1) BRPI1012205A2 (xx)
CA (1) CA2761881C (xx)
HK (1) HK1167859A1 (xx)
MX (1) MX2011012190A (xx)
NZ (1) NZ596137A (xx)
TW (1) TW201102396A (xx)
UY (1) UY32641A (xx)
WO (1) WO2010132599A1 (xx)

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EP2430019A1 (en) 2012-03-21
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AU2010249041B2 (en) 2014-11-13
MX2011012190A (es) 2011-12-08
CA2761881A1 (en) 2010-11-18
AU2010249041A1 (en) 2011-12-01
US20100292208A1 (en) 2010-11-18
KR20120060783A (ko) 2012-06-12
AR080539A1 (es) 2012-04-18
WO2010132599A1 (en) 2010-11-18
CA2761881C (en) 2017-04-04
JP5746685B2 (ja) 2015-07-08
CN102459251B (zh) 2015-05-20
US8399465B2 (en) 2013-03-19
JP2012526837A (ja) 2012-11-01
CN102459251A (zh) 2012-05-16
KR101727650B1 (ko) 2017-04-17
TW201102396A (en) 2011-01-16
UY32641A (es) 2010-11-30
NZ596137A (en) 2013-08-30

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