HK1167657A1 - 螺旋 定向的甾族藥品 - Google Patents
螺旋 定向的甾族藥品Info
- Publication number
- HK1167657A1 HK1167657A1 HK12108245.2A HK12108245A HK1167657A1 HK 1167657 A1 HK1167657 A1 HK 1167657A1 HK 12108245 A HK12108245 A HK 12108245A HK 1167657 A1 HK1167657 A1 HK 1167657A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- helix
- directed
- pharmaceutical products
- steroidal pharmaceutical
- steroidal
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/08—Antiseborrheics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/26—Androgens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/28—Antiandrogens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Physical Education & Sports Medicine (AREA)
- Endocrinology (AREA)
- Dermatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Hematology (AREA)
- Reproductive Health (AREA)
- Urology & Nephrology (AREA)
- Obesity (AREA)
- Gynecology & Obstetrics (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Neurology (AREA)
- Emergency Medicine (AREA)
- Pregnancy & Childbirth (AREA)
- Nutrition Science (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US53512104P | 2004-01-07 | 2004-01-07 |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1167657A1 true HK1167657A1 (zh) | 2012-12-07 |
Family
ID=34749018
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK12108245.2A HK1167657A1 (zh) | 2004-01-07 | 2012-08-22 | 螺旋 定向的甾族藥品 |
Country Status (16)
Country | Link |
---|---|
US (1) | US9090651B2 (zh) |
EP (1) | EP1704161A4 (zh) |
JP (1) | JP4866740B2 (zh) |
KR (2) | KR20130124576A (zh) |
CN (2) | CN1930181A (zh) |
AU (2) | AU2005203922A1 (zh) |
BR (1) | BRPI0506470A (zh) |
CA (1) | CA2551737C (zh) |
HK (1) | HK1167657A1 (zh) |
IL (1) | IL176538A0 (zh) |
MY (1) | MY157898A (zh) |
NO (1) | NO20063564L (zh) |
RU (1) | RU2397176C2 (zh) |
TW (1) | TWI383993B (zh) |
WO (1) | WO2005066194A1 (zh) |
ZA (1) | ZA200605242B (zh) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2005066194A1 (en) | 2004-01-07 | 2005-07-21 | Endorecherche, Inc. | Helix 12 directed steroidal pharmaceutical products |
NZ554619A (en) | 2004-10-20 | 2011-01-28 | Endorech Inc | Sex steroid precursors alone or in combination with a selective estrogen receptor modulator and/or with estrogens and/or a type 5 CGMP phosphodiesterase inhibitor for the prevention and treatment of vaginal dryness and sexual dysfunction in postmenopausal women |
GB0428128D0 (en) * | 2004-12-22 | 2005-01-26 | Avecia Ltd | Process |
US7709516B2 (en) | 2005-06-17 | 2010-05-04 | Endorecherche, Inc. | Helix 12 directed non-steroidal antiandrogens |
US9284345B2 (en) | 2007-04-12 | 2016-03-15 | Endorecherche, Inc. | 17alpha-substituted steroids as systemic antiandrogens and selective androgen receptor modulators |
US8268806B2 (en) | 2007-08-10 | 2012-09-18 | Endorecherche, Inc. | Pharmaceutical compositions |
WO2009105214A2 (en) * | 2008-02-22 | 2009-08-27 | Radius Health, Inc. | Selective androgen receptor modulators |
US8268872B2 (en) | 2008-02-22 | 2012-09-18 | Radius Health, Inc. | Selective androgen receptor modulators |
US20090285893A1 (en) * | 2008-05-19 | 2009-11-19 | The Procter & Gamble Company | Treatment of heart failure in women |
GB2461037A (en) * | 2008-06-17 | 2009-12-23 | Elias Bouras | A method of treating alopecia using a composition comprising a cardiac glycoside |
CA2758774C (en) | 2009-04-15 | 2015-02-03 | Research Triangle Institute | Monoamine reuptake inhibitors |
EP2531029B1 (en) | 2010-02-04 | 2016-10-19 | Radius Health, Inc. | Selective androgen receptor modulators |
PT2568806T (pt) | 2010-05-12 | 2016-08-05 | Radius Health Inc | Regimes terapêuticos |
EP2576514A1 (en) | 2010-06-04 | 2013-04-10 | Exonhit Sa | Substituted isoquinolines and their use as tubulin polymerization inhibitors |
US8642632B2 (en) | 2010-07-02 | 2014-02-04 | Radius Health, Inc. | Selective androgen receptor modulators |
JP5965909B2 (ja) | 2010-09-28 | 2016-08-10 | ラジウス ヘルス,インコーポレイテッド | 選択的アンドロゲン受容体モジュレーター |
CN102746360B (zh) * | 2012-06-19 | 2014-07-02 | 广西民族大学 | 四种喜树碱-甾体缀合物的合成及其应用 |
US9682960B2 (en) | 2013-12-19 | 2017-06-20 | Endorecherche, Inc. | Non-steroidal antiandrogens and selective androgen receptor modulators with a pyridyl moiety |
CN105237605B (zh) * | 2014-07-11 | 2019-01-25 | 上海迪赛诺生物医药有限公司 | 一种用于合成孕二烯酮的中间体及其制备方法和应用 |
CN105237606B (zh) * | 2014-07-11 | 2018-08-24 | 上海创诺制药有限公司 | 一种用于合成去氧孕烯的中间体及其制备方法和应用 |
EP4039253A1 (en) | 2015-04-29 | 2022-08-10 | Radius Pharmaceuticals, Inc. | Methods of treating cancer |
KR102397890B1 (ko) | 2016-06-22 | 2022-05-12 | 일립시스 파마 리미티드 | Ar+ 유방암 치료 방법 |
EP3565542B1 (en) | 2017-01-05 | 2024-04-10 | Radius Pharmaceuticals, Inc. | Polymorphic forms of rad1901-2hcl |
CN108822175B (zh) * | 2018-04-26 | 2021-01-05 | 昆明理工大学 | 3,16-雄甾烯二酮类化合物及其应用 |
AU2019297421A1 (en) | 2018-07-04 | 2021-01-28 | Radius Pharmaceuticals, Inc. | Polymorphic forms of RAD 1901-2HCL |
Family Cites Families (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3797494A (en) | 1969-04-01 | 1974-03-19 | Alza Corp | Bandage for the administration of drug by controlled metering through microporous materials |
US3742951A (en) | 1971-08-09 | 1973-07-03 | Alza Corp | Bandage for controlled release of vasodilators |
DE3333240A1 (de) | 1983-09-12 | 1985-03-28 | Schering AG, 1000 Berlin und 4709 Bergkamen | Mittel zur transdermalen applikation von arzneimittelwirkstoffen |
US4568343A (en) | 1984-10-09 | 1986-02-04 | Alza Corporation | Skin permeation enhancer compositions |
DE3761308D1 (de) * | 1986-07-23 | 1990-02-08 | Akzo Nv | 18-phenylestrane-derivate. |
US4816258A (en) | 1987-02-26 | 1989-03-28 | Alza Corporation | Transdermal contraceptive formulations |
US5064654A (en) | 1989-01-11 | 1991-11-12 | Ciba-Geigy Corporation | Mixed solvent mutually enhanced transdermal therapeutic system |
US5071644A (en) | 1990-08-07 | 1991-12-10 | Mediventures, Inc. | Topical drug delivery with thermo-irreversible gels |
US6060503A (en) | 1991-12-02 | 2000-05-09 | Endorecherche, Inc. | Benzopyran-containing compounds and method for their use |
WO1995018821A2 (en) | 1994-01-06 | 1995-07-13 | Sri International | Novel antiandrogenic agents and related pharmaceutical compositions and methods of use |
US6124115A (en) | 1995-09-22 | 2000-09-26 | Endorecherche Inc. | Production and use of isolated type 5 17β-hydroxysteroid dehydrogenase |
CN1429104A (zh) | 1998-03-11 | 2003-07-09 | 内部研究股份有限公司 | 5型和3型17β-羟基类固醇脱氢酶的抑制剂及其用法 |
JP2004509072A (ja) | 2000-06-28 | 2004-03-25 | ブリストル−マイヤーズ スクイブ カンパニー | 選択的アンドロゲン受容体モジュレーター並びにその同定、設計及び使用方法 |
EP1304334A4 (en) | 2000-06-30 | 2009-06-17 | Chugai Pharmaceutical Co Ltd | NEW ANTIANDROGEN AGENT |
WO2003022835A1 (en) | 2001-09-06 | 2003-03-20 | Schering Corporation | 17beta-hydroxysteroid dehydrogenase type 3 inhibitors for the treatment of androgen dependent diseases |
EP1474127B1 (en) * | 2002-02-15 | 2006-11-15 | Endorecherche, Inc. | Biphenyl derivatives and their use as antiandrogenic agents |
IL163825A0 (en) * | 2002-03-13 | 2005-12-18 | Merck & Co Inc | Fluorinated 4-azasteroid derivatives as androgen receptor modulators |
AU2003223754B2 (en) * | 2002-04-30 | 2007-08-16 | Merck Sharp & Dohme Corp. | 4-azasteroid derivatives as androgen receptor modulators |
WO2005066194A1 (en) | 2004-01-07 | 2005-07-21 | Endorecherche, Inc. | Helix 12 directed steroidal pharmaceutical products |
US7709516B2 (en) | 2005-06-17 | 2010-05-04 | Endorecherche, Inc. | Helix 12 directed non-steroidal antiandrogens |
US9284345B2 (en) | 2007-04-12 | 2016-03-15 | Endorecherche, Inc. | 17alpha-substituted steroids as systemic antiandrogens and selective androgen receptor modulators |
-
2005
- 2005-01-06 WO PCT/CA2005/000011 patent/WO2005066194A1/en active Search and Examination
- 2005-01-06 EP EP05700249A patent/EP1704161A4/en not_active Withdrawn
- 2005-01-06 CA CA002551737A patent/CA2551737C/en not_active Expired - Fee Related
- 2005-01-06 CN CNA200580007350XA patent/CN1930181A/zh active Pending
- 2005-01-06 JP JP2006548053A patent/JP4866740B2/ja not_active Expired - Fee Related
- 2005-01-06 CN CN201110251554.5A patent/CN102358750B/zh not_active Expired - Fee Related
- 2005-01-06 RU RU2006128574/04A patent/RU2397176C2/ru not_active IP Right Cessation
- 2005-01-06 KR KR1020137024835A patent/KR20130124576A/ko not_active Application Discontinuation
- 2005-01-06 KR KR1020067015954A patent/KR101536701B1/ko not_active IP Right Cessation
- 2005-01-06 AU AU2005203922A patent/AU2005203922A1/en not_active Abandoned
- 2005-01-06 BR BRPI0506470-8A patent/BRPI0506470A/pt not_active IP Right Cessation
- 2005-01-06 TW TW094100344A patent/TWI383993B/zh not_active IP Right Cessation
- 2005-01-07 MY MYPI20050071A patent/MY157898A/en unknown
- 2005-01-07 US US11/030,850 patent/US9090651B2/en active Active
-
2006
- 2006-06-25 IL IL176538A patent/IL176538A0/en unknown
- 2006-06-26 ZA ZA200605242A patent/ZA200605242B/en unknown
- 2006-08-07 NO NO20063564A patent/NO20063564L/no not_active Application Discontinuation
-
2009
- 2009-05-22 AU AU2009202038A patent/AU2009202038A1/en not_active Abandoned
-
2012
- 2012-08-22 HK HK12108245.2A patent/HK1167657A1/zh not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
JP4866740B2 (ja) | 2012-02-01 |
KR101536701B1 (ko) | 2015-07-14 |
AU2009202038A1 (en) | 2009-06-11 |
NO20063564L (no) | 2006-10-09 |
AU2005203922A1 (en) | 2005-07-21 |
KR20130124576A (ko) | 2013-11-14 |
MY157898A (en) | 2016-08-15 |
JP2007519635A (ja) | 2007-07-19 |
TW200530264A (en) | 2005-09-16 |
WO2005066194A1 (en) | 2005-07-21 |
CN1930181A (zh) | 2007-03-14 |
BRPI0506470A (pt) | 2007-02-21 |
EP1704161A4 (en) | 2011-06-08 |
EP1704161A1 (en) | 2006-09-27 |
CN102358750B (zh) | 2015-11-25 |
IL176538A0 (en) | 2006-10-05 |
CA2551737C (en) | 2009-11-10 |
TWI383993B (zh) | 2013-02-01 |
CA2551737A1 (en) | 2005-07-21 |
US20050250749A1 (en) | 2005-11-10 |
US9090651B2 (en) | 2015-07-28 |
AU2009202038A2 (en) | 2009-08-06 |
RU2397176C2 (ru) | 2010-08-20 |
RU2006128574A (ru) | 2008-02-20 |
CN102358750A (zh) | 2012-02-22 |
KR20070003851A (ko) | 2007-01-05 |
ZA200605242B (en) | 2007-10-31 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20200106 |