HK1164154A1 - Antitumor combinations containing antibodies recognizing specifically cd38 and cylophosphamide cd38 - Google Patents

Antitumor combinations containing antibodies recognizing specifically cd38 and cylophosphamide cd38

Info

Publication number
HK1164154A1
HK1164154A1 HK12105113.7A HK12105113A HK1164154A1 HK 1164154 A1 HK1164154 A1 HK 1164154A1 HK 12105113 A HK12105113 A HK 12105113A HK 1164154 A1 HK1164154 A1 HK 1164154A1
Authority
HK
Hong Kong
Prior art keywords
cylophosphamide
containing antibodies
antibodies recognizing
combinations containing
recognizing specifically
Prior art date
Application number
HK12105113.7A
Other languages
English (en)
Chinese (zh)
Inventor
Pascale Lejeune
Patricia Vrignaud
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of HK1164154A1 publication Critical patent/HK1164154A1/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/664Amides of phosphorus acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/675Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
HK12105113.7A 2008-11-28 2012-05-24 Antitumor combinations containing antibodies recognizing specifically cd38 and cylophosphamide cd38 HK1164154A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP08291119A EP2191843A1 (en) 2008-11-28 2008-11-28 Antitumor combinations containing antibodies recognizing specifically CD38 and cyclophosphamide
PCT/IB2009/055392 WO2010061360A1 (en) 2008-11-28 2009-11-27 Antitumor combinations containing antibodies recognizing specifically cd38 and cylophosphamide

Publications (1)

Publication Number Publication Date
HK1164154A1 true HK1164154A1 (en) 2012-09-21

Family

ID=40637068

Family Applications (1)

Application Number Title Priority Date Filing Date
HK12105113.7A HK1164154A1 (en) 2008-11-28 2012-05-24 Antitumor combinations containing antibodies recognizing specifically cd38 and cylophosphamide cd38

Country Status (30)

Country Link
US (2) US20110305690A1 (ja)
EP (2) EP2191843A1 (ja)
JP (3) JP2012510464A (ja)
KR (1) KR101749770B1 (ja)
CN (1) CN102264387B (ja)
AR (1) AR074221A1 (ja)
AU (1) AU2009321252B2 (ja)
BR (1) BRPI0922305B1 (ja)
CA (1) CA2745012C (ja)
CL (1) CL2011001256A1 (ja)
CO (1) CO6361947A2 (ja)
CR (1) CR20110283A (ja)
EA (2) EA026008B1 (ja)
EC (1) ECSP11011077A (ja)
HK (1) HK1164154A1 (ja)
HN (1) HN2011001426A (ja)
MA (1) MA32894B1 (ja)
ME (1) ME01139B (ja)
MX (1) MX340062B (ja)
MY (1) MY166530A (ja)
NI (1) NI201100104A (ja)
NZ (1) NZ593147A (ja)
PA (1) PA8850201A1 (ja)
PE (1) PE20110822A1 (ja)
SV (1) SV2011003925A (ja)
TW (1) TWI457346B (ja)
UA (1) UA104161C2 (ja)
UY (1) UY32267A (ja)
WO (1) WO2010061360A1 (ja)
ZA (1) ZA201103920B (ja)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2191840A1 (en) 2008-11-28 2010-06-02 Sanofi-Aventis Antitumor combinations containing antibodies recognizing specifically CD38 and melphalan
HUE031956T2 (en) 2010-09-27 2017-08-28 Morphosys Ag Anti-CD38 antibody and lenalidomide or bortezomib for the treatment of multiple myeloma and NHL
UA112170C2 (uk) 2010-12-10 2016-08-10 Санофі Протипухлинна комбінація, що містить антитіло, яке специфічно розпізнає cd38, і бортезоміб
JOP20210044A1 (ar) 2010-12-30 2017-06-16 Takeda Pharmaceuticals Co الأجسام المضادة لـ cd38
NZ706147A (en) 2012-09-25 2018-10-26 Morphosys Ag Anti-cd38 antibody and melphalan for the treatment of multiple myeloma
US10342869B2 (en) 2012-12-07 2019-07-09 The Regents Of The University Of California Compositions comprising anti-CD38 antibodies and lenalidomide
UA118255C2 (uk) * 2012-12-07 2018-12-26 Санофі Композиція, яка містить антитіло до cd38 і леналідомід
TN2016000142A1 (en) * 2013-10-31 2017-10-06 Sanofi Sa Specific anti-cd38 antibodies for treating human cancers.
US9732154B2 (en) 2014-02-28 2017-08-15 Janssen Biotech, Inc. Anti-CD38 antibodies for treatment of acute lymphoblastic leukemia
US9603927B2 (en) 2014-02-28 2017-03-28 Janssen Biotech, Inc. Combination therapies with anti-CD38 antibodies
US10617757B2 (en) 2014-08-08 2020-04-14 The Regents Of The University Of California Methods for treating multiple myeloma
SG11201701867SA (en) 2014-09-09 2017-04-27 Janssen Biotech Inc Combination therapies with anti-cd38 antibodies
WO2016089960A1 (en) 2014-12-04 2016-06-09 Janssen Biotech, Inc. Anti-cd38 antibodies for treatment of acute myeloid leukemia
IL300548A (en) 2015-05-20 2023-04-01 Janssen Biotech Inc Anti-CD38 antibodies for the treatment of light chain amyloidosis and other CD38-positive hematological malignancies
EA036789B1 (ru) 2015-06-22 2020-12-22 Янссен Байотек, Инк. Комбинированная терапия гемобластозов антителами к cd38 и ингибиторами сурвивина
US20170044265A1 (en) 2015-06-24 2017-02-16 Janssen Biotech, Inc. Immune Modulation and Treatment of Solid Tumors with Antibodies that Specifically Bind CD38
TWI800341B (zh) 2015-11-03 2023-04-21 美商健生生物科技公司 抗cd38抗體之皮下調配物及其用途
US10781261B2 (en) 2015-11-03 2020-09-22 Janssen Biotech, Inc. Subcutaneous formulations of anti-CD38 antibodies and their uses
WO2019035938A1 (en) 2017-08-16 2019-02-21 Elstar Therapeutics, Inc. MULTISPECIFIC MOLECULES BINDING TO BCMA AND USES THEREOF
KR20200079293A (ko) 2017-10-31 2020-07-02 얀센 바이오테크 인코포레이티드 고위험 다발성 골수종을 치료하는 방법
SG11202107319PA (en) 2019-03-15 2021-08-30 Morphosys Ag Anti-cd38 antibodies and pharmaceutical compositions thereof for the treatment of autoantibody-mediated autoimmune disease
US11655302B2 (en) 2019-06-10 2023-05-23 Sanofi Anti-CD38 antibodies and formulations
CA3160502A1 (en) 2019-12-05 2021-06-10 Thomas Ballet Formulations of anti-cd38 antibodies for subcutaneous administration
EP4277930A1 (en) 2021-01-14 2023-11-22 MorphoSys AG Anti-cd38 antibodies and their uses
TW202302642A (zh) 2021-03-01 2023-01-16 德商莫菲西斯公司 用於治療抗體介導移植物排斥用途之抗cd38抗體
TW202321303A (zh) 2021-07-19 2023-06-01 德商莫菲西斯公司 抗pla2r自體抗體媒介膜性腎病變之治療

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4444887A (en) 1979-12-10 1984-04-24 Sloan-Kettering Institute Process for making human antibody producing B-lymphocytes
US4716111A (en) 1982-08-11 1987-12-29 Trustees Of Boston University Process for producing human antibodies
GB8607679D0 (en) 1986-03-27 1986-04-30 Winter G P Recombinant dna product
US5530101A (en) 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
GB8928874D0 (en) 1989-12-21 1990-02-28 Celltech Ltd Humanised antibodies
DE69120146T2 (de) 1990-01-12 1996-12-12 Cell Genesys Inc Erzeugung xenogener antikörper
US5545806A (en) 1990-08-29 1996-08-13 Genpharm International, Inc. Ransgenic non-human animals for producing heterologous antibodies
US5814318A (en) 1990-08-29 1998-09-29 Genpharm International Inc. Transgenic non-human animals for producing heterologous antibodies
EP0519596B1 (en) 1991-05-17 2005-02-23 Merck & Co. Inc. A method for reducing the immunogenicity of antibody variable domains
ES2206447T3 (es) 1991-06-14 2004-05-16 Genentech, Inc. Anticuerpo humanizado para heregulina.
ES2136092T3 (es) 1991-09-23 1999-11-16 Medical Res Council Procedimientos para la produccion de anticuerpos humanizados.
US5639641A (en) 1992-09-09 1997-06-17 Immunogen Inc. Resurfacing of rodent antibodies
ES2304786T3 (es) 1995-04-27 2008-10-16 Amgen Fremont Inc. Anticuerpos anti-il-8 humanos, derivados a partir de xenoratones inmunizados.
EP0823941A4 (en) 1995-04-28 2001-09-19 Abgenix Inc HUMAN ANTIBODIES DERIVED FROM IMMUNIZED XENO MOUSES
US5916771A (en) 1996-10-11 1999-06-29 Abgenix, Inc. Production of a multimeric protein by cell fusion method
DK1500329T3 (da) 1996-12-03 2012-07-09 Amgen Fremont Inc Humane antistoffer, der specifikt binder TNF-alfa
WO1998046645A2 (en) 1997-04-14 1998-10-22 Micromet Gesellschaft Für Biomedizinische Forschung Mbh Method for the production of antihuman antigen receptors and uses thereof
US6235883B1 (en) 1997-05-05 2001-05-22 Abgenix, Inc. Human monoclonal antibodies to epidermal growth factor receptor
CA2329940A1 (en) * 1998-06-05 1999-12-09 Mayo Foundation For Medical Education And Research Use of genetically engineered antibodies to cd38 to treat multiple myeloma
GB0221574D0 (en) * 2002-09-17 2002-10-23 Isis Innovation Treatments
SG10201912554TA (en) * 2005-03-23 2020-02-27 Genmab As Antibodies against cd38 for treatment of multiple myeloma
EP1914242A1 (en) * 2006-10-19 2008-04-23 Sanofi-Aventis Novel anti-CD38 antibodies for the treatment of cancer
AU2009206506B2 (en) * 2008-01-23 2013-01-10 Xencor, Inc. Optimized CD40 antibodies and methods of using the same
UA112170C2 (uk) * 2010-12-10 2016-08-10 Санофі Протипухлинна комбінація, що містить антитіло, яке специфічно розпізнає cd38, і бортезоміб

Also Published As

Publication number Publication date
EA201692041A1 (ru) 2017-05-31
AU2009321252A1 (en) 2010-06-03
WO2010061360A1 (en) 2010-06-03
SV2011003925A (es) 2011-10-07
EA032934B1 (ru) 2019-08-30
KR101749770B1 (ko) 2017-06-22
MX340062B (es) 2016-06-23
ECSP11011077A (es) 2011-07-29
HN2011001426A (es) 2014-01-13
EA201100869A1 (ru) 2011-10-31
NI201100104A (es) 2011-09-26
PE20110822A1 (es) 2011-11-22
ME01139B (me) 2013-03-20
JP6018235B2 (ja) 2016-11-02
CR20110283A (es) 2011-09-20
UY32267A (es) 2010-06-30
CA2745012C (en) 2020-09-15
EP2370097A1 (en) 2011-10-05
CN102264387B (zh) 2015-04-08
EP2370097B1 (en) 2019-01-09
KR20110096552A (ko) 2011-08-30
CL2011001256A1 (es) 2012-01-27
EA026008B1 (ru) 2017-02-28
JP2015120729A (ja) 2015-07-02
JP6215429B2 (ja) 2017-10-18
MX2011005538A (es) 2011-10-10
US20110305690A1 (en) 2011-12-15
JP2017036297A (ja) 2017-02-16
NZ593147A (en) 2012-12-21
BRPI0922305A2 (pt) 2016-06-21
US20170056496A1 (en) 2017-03-02
EP2191843A1 (en) 2010-06-02
UA104161C2 (uk) 2014-01-10
BRPI0922305B1 (pt) 2022-04-05
PA8850201A1 (es) 2010-07-27
AR074221A1 (es) 2010-12-29
ZA201103920B (en) 2012-09-26
CO6361947A2 (es) 2012-01-20
AU2009321252B2 (en) 2016-06-09
JP2012510464A (ja) 2012-05-10
MY166530A (en) 2018-07-10
CA2745012A1 (en) 2010-06-03
TW201024315A (en) 2010-07-01
CN102264387A (zh) 2011-11-30
MA32894B1 (fr) 2011-12-01
TWI457346B (zh) 2014-10-21

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