HK1164057A1 - Pyrido[4,3-b]indoles containing rigid moieties [43-b] - Google Patents
Pyrido[4,3-b]indoles containing rigid moieties [43-b]Info
- Publication number
- HK1164057A1 HK1164057A1 HK12104892.7A HK12104892A HK1164057A1 HK 1164057 A1 HK1164057 A1 HK 1164057A1 HK 12104892 A HK12104892 A HK 12104892A HK 1164057 A1 HK1164057 A1 HK 1164057A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- pyrido
- containing rigid
- rigid moieties
- indoles containing
- indoles
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11051908P | 2008-10-31 | 2008-10-31 | |
US17396009P | 2009-04-29 | 2009-04-29 | |
US24515009P | 2009-09-23 | 2009-09-23 | |
PCT/US2009/062869 WO2010051501A1 (en) | 2008-10-31 | 2009-10-30 | Pyrido (4,3-b) indoles containing rigid moieties |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1164057A1 true HK1164057A1 (en) | 2012-09-21 |
Family
ID=42129313
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK12104892.7A HK1164057A1 (en) | 2008-10-31 | 2012-05-18 | Pyrido[4,3-b]indoles containing rigid moieties [43-b] |
Country Status (11)
Country | Link |
---|---|
US (3) | US8907097B2 (xx) |
EP (1) | EP2346332A4 (xx) |
JP (2) | JP5588991B2 (xx) |
CN (1) | CN102271508B (xx) |
AR (1) | AR073923A1 (xx) |
AU (1) | AU2009308706C1 (xx) |
BR (1) | BRPI0919948A2 (xx) |
CA (1) | CA2742320A1 (xx) |
HK (1) | HK1164057A1 (xx) |
TW (1) | TWI477503B (xx) |
WO (1) | WO2010051501A1 (xx) |
Families Citing this family (34)
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RU2007139634A (ru) | 2007-10-25 | 2009-04-27 | Сергей Олегович Бачурин (RU) | Новые тиазол-, триазол- или оксадиазол-содержащие тетрациклические соединения |
RU2544856C2 (ru) | 2008-01-25 | 2015-03-20 | Сергей Олегович Бачурин | НОВЫЕ ПРОИЗВОДНЫЕ 2,3,4,5-ТЕТРАГИДРО-1-ПИРИДО[4,3-b]ИНДОЛА И СПОСОБЫ ИХ ПРИМЕНЕНИЯ |
CL2009000724A1 (es) | 2008-03-24 | 2009-05-29 | Medivation Technologies Inc | Compuestos derivados de 1,2,3,4-tetrahidro-pirido[3,4-b]indol, moduladores del receptor de histamina, serotonina y dopamina; composicion farmaceutica; kit farmaceutico; y uso para tratar un trastorno cognitivo, psicotico, mediado por neurotransmisores y/o neurologico. |
CA2718790A1 (en) * | 2008-03-24 | 2009-10-01 | Medivation Technologies, Inc. | Bridged heterocyclic compounds and methods of use |
AR073924A1 (es) * | 2008-10-31 | 2010-12-09 | Medivation Technologies Inc | Azepino[4, 5-b]indoles, una composicion farmaceutica y kits que los comprenden y su uso en la modulacion de un receptor de histamina. |
EP2346332A4 (en) | 2008-10-31 | 2012-08-08 | Medivation Technologies Inc | PYRIDOÝ4,3-BINDOLES CONTAINING RIGID FRAGMENTS |
US9162980B2 (en) | 2009-01-09 | 2015-10-20 | Board Of Regents Of The University Of Texas System | Anti-depression compounds |
US9962368B2 (en) | 2009-01-09 | 2018-05-08 | Board Of Regents Of The University Of Texas System | Pro-neurogenic compounds |
US8604074B2 (en) | 2009-01-09 | 2013-12-10 | Board Of Regents Of The University Of Texas System | Pro-neurogenic compounds |
US9095572B2 (en) | 2009-01-09 | 2015-08-04 | Board Of Regents Of The University Of Texas System | Pro-neurogenic compounds |
CA2752073A1 (en) * | 2009-02-11 | 2010-08-19 | Sunovion Pharmaceuticals Inc. | Histamine h3 inverse agonists and antagonists and methods of use thereof |
EP2424366B1 (en) * | 2009-04-29 | 2016-02-17 | Medivation Technologies, Inc. | Pyrido [4, 3-b]indoles and methods of use |
CN102480955B (zh) | 2009-04-29 | 2015-08-05 | 梅迪维新技术公司 | 吡啶并[4,3-b]吲哚类和使用方法 |
WO2011031816A2 (en) * | 2009-09-11 | 2011-03-17 | Sepracor Inc. | Histamine h3 inverse agonists and antagonists and methods of use thereof |
JP5779183B2 (ja) | 2009-09-23 | 2015-09-16 | メディベイション テクノロジーズ, インコーポレイテッド | ピリド[4,3−b]インドールおよび使用方法 |
WO2011038164A1 (en) | 2009-09-23 | 2011-03-31 | Medivation Technologies, Inc. | Bridged heterocyclic compounds and methods of use |
AU2010298168B2 (en) | 2009-09-23 | 2015-11-19 | Medivation Technologies, Inc. | Pyrido(3,4-b)indoles and methods of use |
WO2011103433A1 (en) | 2010-02-18 | 2011-08-25 | Medivation Technologies, Inc. | Pyrido[4,3-b]indole and pyrido[3,4-b]indole derivatives and methods of use |
US9193728B2 (en) | 2010-02-18 | 2015-11-24 | Medivation Technologies, Inc. | Fused tetracyclic pyrido [4,3-B] indole and pyrido [3,4-B] indole derivatives and methods of use |
US9040519B2 (en) | 2010-02-18 | 2015-05-26 | Medivation Technologies, Inc. | Fused tetracyclic pyrido [4,3-B] indole and pyrido [3,4-B] indole derivatives and methods of use |
WO2011103448A1 (en) * | 2010-02-19 | 2011-08-25 | Medivation Technologies, Inc. | Methods and compositions for treating psychotic disorders using antipsychotic combination therapy |
WO2011103430A1 (en) | 2010-02-19 | 2011-08-25 | Medivation Technologies, Inc. | Pyrido[4,3-b]indole and pyrido[3,4-b]indole derivatives and methods of use |
WO2012112964A2 (en) | 2011-02-18 | 2012-08-23 | Medivation Technologies, Inc. | PYRIDO[4,3-b]INDOLE AND PYRIDO[3,4-b]INDOLE DERIVATIVES AND METHODS OF USE |
US20140303144A1 (en) * | 2011-02-18 | 2014-10-09 | Medivation Technologies, Inc. | Compounds and methods of treating hypertension |
WO2012112963A1 (en) | 2011-02-18 | 2012-08-23 | Medivation Technologies, Inc. | Compounds and methods for treatment of hypertension |
IN2013MN01699A (xx) | 2011-02-18 | 2015-06-12 | Medivation Technologies Inc | |
US20150315188A1 (en) * | 2012-08-22 | 2015-11-05 | Medivation Technologies, Inc. | Compounds and methods for treatment of hypertension |
WO2014031170A1 (en) * | 2012-08-22 | 2014-02-27 | Medivation Technologies, Inc. | Pyrido[4,3-b]indole and pyrido[3,4-b]indole derivatives and methods of use |
EP2925129A4 (en) * | 2012-08-24 | 2016-06-08 | Univ Texas | PRO-NEUROGENIC COMPOUNDS |
EP3068388A4 (en) | 2013-11-11 | 2017-04-12 | Board of Regents of the University of Texas System | Neuroprotective compounds and use thereof |
JP6782227B2 (ja) | 2014-09-05 | 2020-11-11 | ザ・ジョンズ・ホプキンス・ユニバーシティー | CaMKII阻害剤及びその使用 |
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EA202191320A1 (ru) | 2020-03-19 | 2021-10-22 | Андрей Александрович ИВАЩЕНКО | Норадренергический и специфически серотонинергический анксиолитик и антидепрессант, способ его получения и применения |
US12016847B2 (en) | 2021-03-12 | 2024-06-25 | Bristol-Myers Squibb Company | Methods of treating prostate cancer |
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IN2013MN01699A (xx) | 2011-02-18 | 2015-06-12 | Medivation Technologies Inc | |
US20140303144A1 (en) | 2011-02-18 | 2014-10-09 | Medivation Technologies, Inc. | Compounds and methods of treating hypertension |
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US20150315188A1 (en) | 2012-08-22 | 2015-11-05 | Medivation Technologies, Inc. | Compounds and methods for treatment of hypertension |
-
2009
- 2009-10-30 EP EP09824199A patent/EP2346332A4/en not_active Withdrawn
- 2009-10-30 AR ARP090104220A patent/AR073923A1/es unknown
- 2009-10-30 BR BRPI0919948-9A patent/BRPI0919948A2/pt not_active IP Right Cessation
- 2009-10-30 TW TW098137048A patent/TWI477503B/zh not_active IP Right Cessation
- 2009-10-30 CN CN200980153434.2A patent/CN102271508B/zh not_active Expired - Fee Related
- 2009-10-30 CA CA2742320A patent/CA2742320A1/en not_active Abandoned
- 2009-10-30 US US12/610,217 patent/US8907097B2/en not_active Expired - Fee Related
- 2009-10-30 JP JP2011534826A patent/JP5588991B2/ja not_active Expired - Fee Related
- 2009-10-30 AU AU2009308706A patent/AU2009308706C1/en not_active Ceased
- 2009-10-30 WO PCT/US2009/062869 patent/WO2010051501A1/en active Application Filing
-
2012
- 2012-05-18 HK HK12104892.7A patent/HK1164057A1/xx not_active IP Right Cessation
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2013
- 2013-03-08 US US13/791,544 patent/US8906925B2/en not_active Expired - Fee Related
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2014
- 2014-04-21 JP JP2014087277A patent/JP2014133759A/ja not_active Withdrawn
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Also Published As
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TW201022264A (en) | 2010-06-16 |
US20150051218A1 (en) | 2015-02-19 |
US8906925B2 (en) | 2014-12-09 |
JP2012507566A (ja) | 2012-03-29 |
CN102271508A (zh) | 2011-12-07 |
AU2009308706A1 (en) | 2010-05-06 |
TWI477503B (zh) | 2015-03-21 |
BRPI0919948A2 (pt) | 2015-08-25 |
AR073923A1 (es) | 2010-12-09 |
US9458155B2 (en) | 2016-10-04 |
CN102271508B (zh) | 2015-04-29 |
US20130190322A1 (en) | 2013-07-25 |
EP2346332A1 (en) | 2011-07-27 |
US8907097B2 (en) | 2014-12-09 |
US20100216814A1 (en) | 2010-08-26 |
JP2014133759A (ja) | 2014-07-24 |
CA2742320A1 (en) | 2010-05-06 |
JP5588991B2 (ja) | 2014-09-10 |
AU2009308706C1 (en) | 2016-01-21 |
EP2346332A4 (en) | 2012-08-08 |
WO2010051501A1 (en) | 2010-05-06 |
AU2009308706B2 (en) | 2015-09-03 |
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