HK1162121A1 - Methods and compositions for diagnosis and prognosis of renal injury and renal failure - Google Patents
Methods and compositions for diagnosis and prognosis of renal injury and renal failureInfo
- Publication number
- HK1162121A1 HK1162121A1 HK12102533.6A HK12102533A HK1162121A1 HK 1162121 A1 HK1162121 A1 HK 1162121A1 HK 12102533 A HK12102533 A HK 12102533A HK 1162121 A1 HK1162121 A1 HK 1162121A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- renal
- prognosis
- diagnosis
- compositions
- methods
- Prior art date
Links
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/15—Medicinal preparations ; Physical properties thereof, e.g. dissolubility
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
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- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
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- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
- G16B40/10—Signal processing, e.g. from mass spectrometry [MS] or from PCR
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
- G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
- G01N2333/4701—Details
- G01N2333/4703—Regulators; Modulating activity
- G01N2333/4704—Inhibitors; Supressors
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
- G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
- G01N2333/4701—Details
- G01N2333/4709—Amyloid plaque core protein
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/475—Assays involving growth factors
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/475—Assays involving growth factors
- G01N2333/4753—Hepatocyte growth factor; Scatter factor; Tumor cytotoxic factor II
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/52—Assays involving cytokines
- G01N2333/54—Interleukins [IL]
- G01N2333/5434—IL-12
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/52—Assays involving cytokines
- G01N2333/54—Interleukins [IL]
- G01N2333/5446—IL-16
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/52—Assays involving cytokines
- G01N2333/54—Interleukins [IL]
- G01N2333/55—IL-2
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/52—Assays involving cytokines
- G01N2333/555—Interferons [IFN]
- G01N2333/57—IFN-gamma
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/775—Apolipopeptides
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/914—Hydrolases (3)
- G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
- G01N2333/95—Proteinases, i.e. endopeptidases (3.4.21-3.4.99)
- G01N2333/964—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue
- G01N2333/96425—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals
- G01N2333/96427—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general
- G01N2333/9643—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general with EC number
- G01N2333/96486—Metalloendopeptidases (3.4.24)
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/914—Hydrolases (3)
- G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
- G01N2333/95—Proteinases, i.e. endopeptidases (3.4.21-3.4.99)
- G01N2333/964—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue
- G01N2333/96425—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals
- G01N2333/96427—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general
- G01N2333/9643—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general with EC number
- G01N2333/96486—Metalloendopeptidases (3.4.24)
- G01N2333/96491—Metalloendopeptidases (3.4.24) with definite EC number
- G01N2333/96494—Matrix metalloproteases, e. g. 3.4.24.7
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/08—Hepato-biliairy disorders other than hepatitis
- G01N2800/085—Liver diseases, e.g. portal hypertension, fibrosis, cirrhosis, bilirubin
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/34—Genitourinary disorders
- G01N2800/347—Renal failures; Glomerular diseases; Tubulointerstitial diseases, e.g. nephritic syndrome, glomerulonephritis; Renovascular diseases, e.g. renal artery occlusion, nephropathy
Applications Claiming Priority (12)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11307408P | 2008-11-10 | 2008-11-10 | |
US11504908P | 2008-11-15 | 2008-11-15 | |
US11715808P | 2008-11-22 | 2008-11-22 | |
US11716108P | 2008-11-22 | 2008-11-22 | |
US11716308P | 2008-11-22 | 2008-11-22 | |
US11716208P | 2008-11-22 | 2008-11-22 | |
US11718008P | 2008-11-22 | 2008-11-22 | |
US11717808P | 2008-11-22 | 2008-11-22 | |
US11715108P | 2008-11-22 | 2008-11-22 | |
US11716008P | 2008-11-22 | 2008-11-22 | |
US11716808P | 2008-11-22 | 2008-11-22 | |
PCT/US2009/063906 WO2010054389A1 (en) | 2008-11-10 | 2009-11-10 | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1162121A1 true HK1162121A1 (en) | 2012-08-24 |
Family
ID=42153314
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK12102533.6A HK1162121A1 (en) | 2008-11-10 | 2012-03-13 | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
HK15104092.2A HK1203619A1 (en) | 2008-11-10 | 2015-04-28 | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK15104092.2A HK1203619A1 (en) | 2008-11-10 | 2015-04-28 | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
Country Status (12)
Country | Link |
---|---|
US (3) | US8993250B2 (de) |
EP (2) | EP2913676A1 (de) |
JP (1) | JP5752600B2 (de) |
KR (1) | KR20110084286A (de) |
CN (2) | CN102264230B (de) |
AU (1) | AU2009313189B2 (de) |
BR (1) | BRPI0922021A2 (de) |
CA (1) | CA2742113A1 (de) |
HK (2) | HK1162121A1 (de) |
MX (1) | MX2011004767A (de) |
NZ (1) | NZ592488A (de) |
WO (1) | WO2010054389A1 (de) |
Families Citing this family (51)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SG10201704689XA (en) | 2008-01-18 | 2017-07-28 | Harvard College | Methods of detecting signatures of disease or conditions in bodily fluids |
BRPI0907802A2 (pt) * | 2008-02-29 | 2016-08-23 | Univ Nagoya Nat Univ Corp | biomarcador para lesão renal aguda e estimativa de seu prognóstico, e sua aplicação |
MX2011002233A (es) | 2008-08-28 | 2011-09-27 | Astute Medical Inc | Metodos y composiciones para la diagnosis y prognosis de daño renal y falla renal. |
WO2010025434A1 (en) | 2008-08-29 | 2010-03-04 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
NZ628843A (en) | 2008-10-21 | 2016-02-26 | Astute Medical Inc | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
BRPI0922021A2 (pt) | 2008-11-10 | 2019-09-24 | Astute Medical Inc | método para avaliar a condição renal em um indivíduo, e, uso de um ou mais marcadores de lesão renal |
US9229010B2 (en) | 2009-02-06 | 2016-01-05 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
WO2011017654A1 (en) | 2009-08-07 | 2011-02-10 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
US10324093B2 (en) | 2009-11-07 | 2019-06-18 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
CA2784889C (en) | 2009-12-20 | 2018-06-19 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
SI2666872T1 (sl) | 2010-02-05 | 2016-08-31 | Astute Medical, Inc. | Postopki in sestavki za diagnozo in prognozo ledvične poškodbe in odpovedi ledvic |
NZ602056A (en) | 2010-02-26 | 2014-11-28 | Astute Medical Inc | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
US20130203074A1 (en) | 2010-06-23 | 2013-08-08 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
WO2011162821A1 (en) | 2010-06-23 | 2011-12-29 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
NZ606124A (en) * | 2010-06-23 | 2015-05-29 | Astute Medical Inc | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
MX361944B (es) | 2010-07-23 | 2018-12-19 | President And Fellows Of Harvard College Star | Metodos para detectar firmas de enfermedad o condiciones en fluidos corporales. |
WO2012012704A2 (en) | 2010-07-23 | 2012-01-26 | President And Fellows Of Harvard College | Methods of detecting kidney-associated diseases or conditions |
AU2011280997A1 (en) | 2010-07-23 | 2013-02-28 | President And Fellows Of Harvard College | Methods of detecting autoimmune or immune-related diseases or conditions |
US20130203624A1 (en) | 2010-07-23 | 2013-08-08 | President And Fellows Of Harvard College | Methods of Detecting Prenatal or Pregnancy-Related Diseases or Conditions |
JP2013541323A (ja) | 2010-07-23 | 2013-11-14 | プレジデント アンド フェロウズ オブ ハーバード カレッジ | 貪食細胞を用いて疾患または症状のシグネチャを検出する方法 |
US20150056641A1 (en) * | 2011-01-08 | 2015-02-26 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
EP2729805A4 (de) * | 2011-07-09 | 2015-07-22 | Astute Medical Inc | Verfahren und zusammensetzungen zur diagnose und prognose von nierenverletzungen und niereninsuffizienz |
ES2721907T3 (es) * | 2011-08-26 | 2019-08-06 | Astute Medical Inc | Métodos y composiciones para el diagnóstico y pronóstico de lesión renal e insuficiencia renal |
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WO2013096740A1 (en) * | 2011-12-21 | 2013-06-27 | Alere San Diego Inc. | Methods and compositions for assigning likelihood of chronic kidney disease progression |
CN102659937B (zh) * | 2012-03-16 | 2014-01-08 | 杭州贤至生物科技有限公司 | 一种重组蛋白及其单克隆抗体的制备方法和应用 |
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US9353523B2 (en) | 2012-09-27 | 2016-05-31 | Max Life, LLC | Insulated wall panel |
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US11585814B2 (en) | 2013-03-09 | 2023-02-21 | Immunis.Ai, Inc. | Methods of detecting prostate cancer |
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US11461766B1 (en) * | 2014-04-30 | 2022-10-04 | Wells Fargo Bank, N.A. | Mobile wallet using tokenized card systems and methods |
WO2016040843A1 (en) | 2014-09-11 | 2016-03-17 | Harry Stylli | Methods of detecting prostate cancer |
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US10473671B2 (en) * | 2014-12-18 | 2019-11-12 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
EP3281011A4 (de) | 2015-04-09 | 2018-11-21 | Astute Medical, Inc. | Verfahren und zusammensetzungen zur diagnose und prognose von nierenläsion und niereninsuffizienz |
CA2983828A1 (en) * | 2015-04-30 | 2016-11-03 | Idexx Laboratories, Inc. | Specific detection of clusterin isoforms |
WO2017214203A1 (en) | 2016-06-06 | 2017-12-14 | Astute Medical, Inc. | Management of acute kidney injury using insulin-like growth factor-binding protein 7 and tissue inhibitor of metalloproteinase 2 |
JP6842195B2 (ja) | 2016-12-19 | 2021-03-17 | 国立大学法人大阪大学 | インビトロでのIgM型メモリーB細胞分化培養系を用いた臓器移植後抗体関連型拒絶反応の早期診断法 |
WO2018145117A1 (en) | 2017-02-06 | 2018-08-09 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
US20180322956A1 (en) | 2017-05-05 | 2018-11-08 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Time Window-Based Platform for the Rapid Stratification of Blunt Trauma Patients into Distinct Outcome Cohorts |
GB201804648D0 (en) * | 2018-03-22 | 2018-05-09 | Randox Laboratories Ltd | Combination biomarker |
CA3101470A1 (en) | 2018-05-24 | 2019-11-28 | Renibus Therapeutics, Inc. | Methods of treating patients at risk for renal injury and renal failure |
CN113178243A (zh) * | 2021-04-26 | 2021-07-27 | 南京医科大学 | 体外循环心脏手术后急性肾损伤早期预警方法及系统 |
GB202206257D0 (en) * | 2022-04-29 | 2022-06-15 | Randox Laboratories Ltd | Biomarkers of diabetic nephropathy |
GB202208742D0 (en) * | 2022-06-14 | 2022-07-27 | Tintra 3 0 Ltd | Authentication and association of multi-platform accounts and method of obfuscating senstive personal data in processes requiring personal identification |
Family Cites Families (113)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SU1429031A1 (ru) | 1986-06-20 | 1988-10-07 | Калининский Государственный Медицинский Институт | Способ дифференциальной диагностики гломерулонефрита и пиелонефрита |
US5223409A (en) | 1988-09-02 | 1993-06-29 | Protein Engineering Corp. | Directed evolution of novel binding proteins |
US5939272A (en) | 1989-01-10 | 1999-08-17 | Biosite Diagnostics Incorporated | Non-competitive threshold ligand-receptor assays |
US5028535A (en) | 1989-01-10 | 1991-07-02 | Biosite Diagnostics, Inc. | Threshold ligand-receptor assay |
US5922615A (en) | 1990-03-12 | 1999-07-13 | Biosite Diagnostics Incorporated | Assay devices comprising a porous capture membrane in fluid-withdrawing contact with a nonabsorbent capillary network |
AU658374B2 (en) | 1990-09-14 | 1995-04-13 | Biosite Diagnostics Incorporated | Antibodies to complexes of ligand receptors and ligands and their utility in ligand-receptor assays |
US5955377A (en) | 1991-02-11 | 1999-09-21 | Biostar, Inc. | Methods and kits for the amplification of thin film based assays |
WO1992018868A1 (en) | 1991-04-10 | 1992-10-29 | Biosite Diagnostics Incorporated | Crosstalk inhibitors and their uses |
EP0579767B1 (de) | 1991-04-11 | 2000-08-23 | Biosite Diagnostics Inc. | Neue konjugate und testverfahren für die gleichzeitige bestimmung von multiplen liganden |
US5885527A (en) | 1992-05-21 | 1999-03-23 | Biosite Diagnostics, Inc. | Diagnostic devices and apparatus for the controlled movement of reagents without membrances |
US6143576A (en) | 1992-05-21 | 2000-11-07 | Biosite Diagnostics, Inc. | Non-porous diagnostic devices for the controlled movement of reagents |
US5494829A (en) | 1992-07-31 | 1996-02-27 | Biostar, Inc. | Devices and methods for detection of an analyte based upon light interference |
US5824799A (en) | 1993-09-24 | 1998-10-20 | Biosite Diagnostics Incorporated | Hybrid phthalocyanine derivatives and their uses |
US6498142B1 (en) | 1996-05-06 | 2002-12-24 | Curis, Inc. | Morphogen treatment for chronic renal failure |
CA2257851C (en) | 1996-05-24 | 2011-11-15 | Biogen, Inc. | Modulators of tissue regeneration |
US5753455A (en) | 1996-09-03 | 1998-05-19 | Bayer Corporation | Method for the detection of lysozyme using a protein error indicator dye in conjunction with an alkane sulfonic acid |
US6113855A (en) | 1996-11-15 | 2000-09-05 | Biosite Diagnostics, Inc. | Devices comprising multiple capillarity inducing surfaces |
US5947124A (en) | 1997-03-11 | 1999-09-07 | Biosite Diagnostics Incorporated | Diagnostic for determining the time of a heart attack |
US6057098A (en) | 1997-04-04 | 2000-05-02 | Biosite Diagnostics, Inc. | Polyvalent display libraries |
WO1998055508A2 (en) | 1997-06-03 | 1998-12-10 | Sagami Chemical Research Center | HUMAN PROTEINS HAVING TRANSMEMBRANE DOMAINS AND DNAs ENCODING THESE PROTEINS |
US20060223077A1 (en) | 1997-06-06 | 2006-10-05 | Human Genome Sciences, Inc. | 207 human secreted proteins |
US6218122B1 (en) | 1998-06-19 | 2001-04-17 | Rosetta Inpharmatics, Inc. | Methods of monitoring disease states and therapies using gene expression profiles |
US6958147B1 (en) | 1998-10-26 | 2005-10-25 | Licentia Ltd | Use of VEGF-C to prevent restenosis |
EP1141728B1 (de) | 1998-12-21 | 2007-10-17 | Monash University | Nachweis von erkrankungen der nieren und behandlung |
RU2180965C1 (ru) | 2000-07-03 | 2002-03-27 | Габбасова Наталья Вадимовна | Способ дифференциальной диагностики заболеваний почек |
AU2002216273A1 (en) | 2000-12-29 | 2002-07-16 | Oxford Glycosciences (Uk) Limited | Proteins, genes and their use for diagnosis and treatment of kidney response |
CA2442820A1 (en) | 2001-03-29 | 2002-10-10 | Van Andel Institute | Microarray gene expression profiling in clear cell renal cell carcinoma: prognosis and drug target identification |
US20070015146A1 (en) | 2001-05-22 | 2007-01-18 | Gene Logic, Inc. | Molecular nephrotoxicology modeling |
US7235358B2 (en) | 2001-06-08 | 2007-06-26 | Expression Diagnostics, Inc. | Methods and compositions for diagnosing and monitoring transplant rejection |
US20030003588A1 (en) | 2001-06-28 | 2003-01-02 | Comper Wayne D. | Method for kidney disease detection by protein profiling |
EP1418813A4 (de) | 2001-07-24 | 2009-03-04 | Univ Yale | Verfahren, zusammensetzungen und kits bezüglich chitinasen und chitinaseartigen molekülen sowie entzündungskrankheiten |
US6784154B2 (en) | 2001-11-01 | 2004-08-31 | University Of Utah Research Foundation | Method of use of erythropoietin to treat ischemic acute renal failure |
US8404229B2 (en) | 2001-12-07 | 2013-03-26 | Cytori Therapeutics, Inc. | Methods of using adipose derived stem cells to treat acute tubular necrosis |
GB0130557D0 (en) | 2001-12-20 | 2002-02-06 | Serono Internat S A | Proteins |
US20070233391A1 (en) | 2002-03-07 | 2007-10-04 | Cambridge University Technical Service Limited (CUTS) | Scd fingerprints |
WO2003081201A2 (en) | 2002-03-21 | 2003-10-02 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Peripheral blood cell markers useful for diagnosing multiple sclerosis and methods and kits utilizing same |
CN1376923A (zh) * | 2002-04-08 | 2002-10-30 | 刘友华 | 肝细胞生长因子的测定方法 |
US7138229B2 (en) | 2002-12-06 | 2006-11-21 | Renovar, Inc. | Systems and methods for characterizing kidney diseases |
US7138230B2 (en) * | 2002-12-06 | 2006-11-21 | Renovar, Inc. | Systems and methods for characterizing kidney diseases |
AU2003281287A1 (en) * | 2002-07-04 | 2004-01-23 | Oxford Glycosciences (Uk) Ltd | Toxicity markers |
GB0215509D0 (en) * | 2002-07-04 | 2002-08-14 | Novartis Ag | Marker genes |
US6941172B2 (en) | 2002-11-18 | 2005-09-06 | Zvi Nachum | Method and device for restoring kidney function using electromagnetic stimulation |
US20060063156A1 (en) | 2002-12-06 | 2006-03-23 | Willman Cheryl L | Outcome prediction and risk classification in childhood leukemia |
CN1791797A (zh) | 2003-03-27 | 2006-06-21 | 儿童医院医疗中心 | 用于检测肾小管细胞损伤的早发的方法和试剂盒 |
KR20120035234A (ko) | 2003-04-11 | 2012-04-13 | 메디뮨 엘엘씨 | 재조합 il?9 항체 및 그의 용도 |
US7560244B2 (en) | 2003-06-04 | 2009-07-14 | Joslin Diabetes Center, Inc. | Method of evaluating a subject for risk or predisposition of reduced renal function over time |
US20050148029A1 (en) | 2003-09-29 | 2005-07-07 | Biosite, Inc. | Methods and compositions for determining treatment regimens in systemic inflammatory response syndromes |
DK1687636T3 (da) | 2003-09-29 | 2009-05-11 | Peas Inst Ab | Hurtig bestemmelse af forskellige former for hepatocytvækstfaktor (HGF) i legemsvæsker |
GB0329288D0 (en) | 2003-12-18 | 2004-01-21 | Inverness Medical Switzerland | Monitoring method and apparatus |
WO2005087264A1 (en) | 2004-03-17 | 2005-09-22 | Academisch Ziekenhuis Bij De Universiteit Van Amsterdam | Cd44-targeting for reducing/preventing ischemia-reperfusion-injury |
JP2007535324A (ja) | 2004-04-26 | 2007-12-06 | チルドレンズ メディカル センター コーポレーション | 疾患検出のための血小板バイオマーカー |
US20050272101A1 (en) | 2004-06-07 | 2005-12-08 | Prasad Devarajan | Method for the early detection of renal injury |
US7588892B2 (en) | 2004-07-19 | 2009-09-15 | Entelos, Inc. | Reagent sets and gene signatures for renal tubule injury |
WO2006008661A2 (en) | 2004-07-19 | 2006-01-26 | Neurochem (International) Limited | Diagnostic methods of multiple organ amyloidosis |
US7141382B1 (en) | 2004-10-12 | 2006-11-28 | Parikh Chirag R | Methods for detection of IL-18 as an early marker for diagnosis of acute renal failure and predictor of mortality |
EP1846576A4 (de) | 2005-02-01 | 2009-01-07 | Us Gov Health & Human Serv | Biomarker für gewebestatus |
US7741038B2 (en) | 2005-03-14 | 2010-06-22 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and compositions for evaluating graft survival in a solid organ transplant recipient |
US7608413B1 (en) | 2005-03-25 | 2009-10-27 | Celera Corporation | Kidney disease targets and uses thereof |
US20070037232A1 (en) | 2005-03-31 | 2007-02-15 | Barasch Jonathan M | Detection of NGAL in chronic renal disease |
EP2339032B1 (de) | 2005-04-18 | 2016-12-28 | MDNA Life Sciences Inc. | Mitochondriale Mutationen und Neuanordnungen als Diagnosewerkzeug zum Nachweis von Sonneneinstrahlungsbelastung, Prostatakrebs und andere Krebsarten |
US20070087387A1 (en) | 2005-04-21 | 2007-04-19 | Prasad Devarajan | Method for the Early Detection of Renal Disease Using Proteomics |
WO2007013919A2 (en) | 2005-07-21 | 2007-02-01 | The Johns Hopkins University | Methods of detecting and treating acute kidney injury |
US7759077B2 (en) | 2005-08-02 | 2010-07-20 | Shariat Shahrokh F | Soluble fas urinary marker for the detection of bladder transitional cell carcinoma |
EP1757940A1 (de) | 2005-08-26 | 2007-02-28 | Cézanne S.A.S. | In vitro Methode zur Diagnose und zum Monitoring von Nierenzellkarzinom unter Verwendung von MMP-7 als humoraler Biomarker für Nierenzellkarzinom |
WO2007041623A2 (en) | 2005-10-03 | 2007-04-12 | Biosite Incorporated | Methods and compositions for diagnosis and/or prognosis in systemic inflammatory response syndromes |
US20080090304A1 (en) | 2006-10-13 | 2008-04-17 | Barasch Jonathan Matthew | Diagnosis and monitoring of chronic renal disease using ngal |
US8329408B2 (en) | 2005-10-31 | 2012-12-11 | Bayer Healthcare Llc | Methods for prognosis and monitoring cancer therapy |
US10716749B2 (en) | 2005-11-03 | 2020-07-21 | Palo Alto Investors | Methods and compositions for treating a renal disease condition in a subject |
US20080133141A1 (en) | 2005-12-22 | 2008-06-05 | Frost Stephen J | Weighted Scoring Methods and Use Thereof in Screening |
TW200726845A (en) | 2006-01-02 | 2007-07-16 | Nat Defense Medical Ct | Biomarker molecular of renal illness and detecting method for the same |
GB0605217D0 (en) | 2006-03-15 | 2006-04-26 | Novartis Ag | Method and compositions for assessing acute rejection |
GB0606776D0 (en) | 2006-04-03 | 2006-05-10 | Novartis Pharma Ag | Predictive biomarkers for chronic allograft nephropathy |
US7662578B2 (en) | 2006-04-21 | 2010-02-16 | Children's Hospital Medical Center | Method and kit for the early detection of impaired renal status |
US20080038269A1 (en) * | 2006-05-25 | 2008-02-14 | Mount Sinai Hospital | Methods for detecting and treating kidney disease |
WO2008084331A2 (en) | 2006-06-21 | 2008-07-17 | Hopitaux Universitaires De Geneve | Biomarkers for renal disorders |
US20090298073A1 (en) | 2006-06-30 | 2009-12-03 | Gerhold David L | Kidney Toxicity Biomarkers |
WO2008009132A1 (en) | 2006-07-21 | 2008-01-24 | The Governors Of The University Of Alberta | Tissue rejection |
GB0617429D0 (en) | 2006-09-05 | 2006-10-18 | Electrophoretics Ltd | Markers of renal transplant rejection and renal damage |
US20080206794A1 (en) | 2006-09-15 | 2008-08-28 | Renovar Incorporated | Systems And Methods For Characterizing Contrast Induced-Nephropathy |
WO2008060607A2 (en) | 2006-11-14 | 2008-05-22 | Biosite Incorporated | Methods and compositions for monitoring and risk prediction in cardiorenal syndrome |
EP2064550B1 (de) | 2006-12-08 | 2015-02-25 | The Children's Hospital Of Philadelphia | Verwendung von prrg4 in tumordiagnoseverfahren |
GB0701626D0 (en) | 2007-01-22 | 2007-03-07 | Cambridge Entpr Ltd | Methods and biomarkers for diagnosing and monitoring psychotic disorders |
WO2008104803A2 (en) | 2007-02-26 | 2008-09-04 | Oxford Genome Sciences (Uk) Limited | Proteins |
US8221995B2 (en) | 2007-03-23 | 2012-07-17 | Seok-Won Lee | Methods and compositions for diagnosis and/or prognosis in systemic inflammatory response syndromes |
US8609812B2 (en) * | 2007-03-26 | 2013-12-17 | Novartis Ag | Use of β-2-microglobulin to assess glomerular alterations and damage in the kidney |
US20110129820A1 (en) | 2007-04-10 | 2011-06-02 | Integragen | Human diabetes susceptibility tnfrsf10b gene |
US8080394B2 (en) | 2007-04-27 | 2011-12-20 | Brigham And Women's Hospital | Method for determining predisposition to pulmonary infection |
US9091695B2 (en) | 2007-06-01 | 2015-07-28 | Laboratory Corporation Of America Holdings | Methods and systems for quantification of peptides and other analytes |
WO2008154238A1 (en) | 2007-06-06 | 2008-12-18 | Siemens Healthcare Diagnostics Inc. | Predictive diagnostics for kidney disease |
US20090047689A1 (en) | 2007-06-20 | 2009-02-19 | John Kolman | Autoantigen biomarkers for early diagnosis of lung adenocarcinoma |
US20100267041A1 (en) | 2007-09-14 | 2010-10-21 | Predictive Biosciences, Inc. | Serial analysis of biomarkers for disease diagnosis |
WO2009038742A2 (en) | 2007-09-20 | 2009-03-26 | Caritas St. Elizabeth's Medical Center Of Boston, Inc. | Method for estimating risk of acute kidney injury |
WO2009039421A1 (en) | 2007-09-20 | 2009-03-26 | University Of Louisville Research Foundation, Inc. | Peptide biomarkers predictive of renal function decline and kidney disease |
US8003333B2 (en) | 2007-09-28 | 2011-08-23 | Mayo Foundation For Medical Education And Research | Serum biomarkers for early detection of acute cellular rejection |
BRPI0907802A2 (pt) | 2008-02-29 | 2016-08-23 | Univ Nagoya Nat Univ Corp | biomarcador para lesão renal aguda e estimativa de seu prognóstico, e sua aplicação |
US20090298106A1 (en) | 2008-05-30 | 2009-12-03 | Therapeutic Monitoring Services, L.L.C. | Methods for Monitoring Immunosuppressant Drug Levels, Renal Function, and Hepatic Function Using Small Volume Samples |
US8241861B1 (en) | 2008-07-08 | 2012-08-14 | Insilicos, Llc | Methods and compositions for diagnosis or prognosis of cardiovascular disease |
EP2149613A1 (de) | 2008-07-28 | 2010-02-03 | Greenwood Genetic Center, Inc. | Verfahren zur Bestimmung der Dysregulierung der Methylation von hirnexprimierten Genen auf dem X-Chromosom zur Diagnose von autistischen Spektrumsstörungen |
WO2010022210A2 (en) | 2008-08-21 | 2010-02-25 | Pxbiosciences Llc | Diagnosis and monitoring of renal failure using peptide biomarkers |
MX2011002233A (es) | 2008-08-28 | 2011-09-27 | Astute Medical Inc | Metodos y composiciones para la diagnosis y prognosis de daño renal y falla renal. |
WO2010025434A1 (en) | 2008-08-29 | 2010-03-04 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
US8501489B2 (en) | 2008-09-26 | 2013-08-06 | University of Pittsburgh—of the Commonwealth System of Higher Education | Urinary biomarkers to predict long-term dialysis |
WO2010048347A2 (en) | 2008-10-21 | 2010-04-29 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
NZ628843A (en) | 2008-10-21 | 2016-02-26 | Astute Medical Inc | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
BRPI0922021A2 (pt) | 2008-11-10 | 2019-09-24 | Astute Medical Inc | método para avaliar a condição renal em um indivíduo, e, uso de um ou mais marcadores de lesão renal |
US9229010B2 (en) | 2009-02-06 | 2016-01-05 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
NZ601575A (en) | 2009-02-06 | 2014-08-29 | Astute Medical Inc | Methods and compositions for diagnosis and prognosis of renal injury and failure |
WO2010111746A1 (en) | 2009-04-03 | 2010-10-07 | Vegenics Limited | Anti-vegf-d antibodies |
WO2010128158A1 (en) | 2009-05-08 | 2010-11-11 | Novartis Ag | Diagnostic biomarkers for fibrotic disorders |
US20110065136A1 (en) | 2009-08-07 | 2011-03-17 | Rules-Based Medicine, Inc. | Methods and Devices for Detecting Glomerulonephritis and Associated Disorders |
EP2480882A4 (de) | 2009-09-21 | 2013-07-10 | Astute Medical Inc | Verfahren und zusammensetzungen zur diagnose und prognose von nierenverletzungen und niereninsuffizienz |
CA2784889C (en) | 2009-12-20 | 2018-06-19 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
US20130035290A1 (en) | 2011-05-17 | 2013-02-07 | Yale University | Chitinase-3-Like Protein 1 as a Biomarker of Recovery from Kidney Injury |
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US9470695B2 (en) | 2016-10-18 |
CN104330574A (zh) | 2015-02-04 |
EP2361018B1 (de) | 2015-04-01 |
US20170030927A1 (en) | 2017-02-02 |
AU2009313189A1 (en) | 2010-05-14 |
CN102264230A (zh) | 2011-11-30 |
JP5752600B2 (ja) | 2015-07-22 |
US8993250B2 (en) | 2015-03-31 |
HK1203619A1 (en) | 2015-10-30 |
EP2913676A1 (de) | 2015-09-02 |
CN102264230B (zh) | 2014-12-10 |
AU2009313189B2 (en) | 2014-10-23 |
CA2742113A1 (en) | 2010-05-14 |
EP2361018A1 (de) | 2011-08-31 |
US20110306063A1 (en) | 2011-12-15 |
WO2010054389A1 (en) | 2010-05-14 |
CN104330574B (zh) | 2017-04-12 |
EP2361018A4 (de) | 2012-07-11 |
US20160054336A1 (en) | 2016-02-25 |
MX2011004767A (es) | 2011-09-06 |
KR20110084286A (ko) | 2011-07-21 |
JP2012508382A (ja) | 2012-04-05 |
NZ592488A (en) | 2012-10-26 |
BRPI0922021A2 (pt) | 2019-09-24 |
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