HK1156335A1 - 合成基本上單分散的低聚體混合物的方法 - Google Patents

合成基本上單分散的低聚體混合物的方法

Info

Publication number
HK1156335A1
HK1156335A1 HK11110151.1A HK11110151A HK1156335A1 HK 1156335 A1 HK1156335 A1 HK 1156335A1 HK 11110151 A HK11110151 A HK 11110151A HK 1156335 A1 HK1156335 A1 HK 1156335A1
Authority
HK
Hong Kong
Prior art keywords
oligomers
synthesizing
substantially monodispersed
monodispersed mixture
mixture
Prior art date
Application number
HK11110151.1A
Other languages
English (en)
Inventor
Reena Vijayaraghavan
Srinivas Pullela Venkata
Chandrashekar Aswathanarayanappa
Original Assignee
Biocon Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biocon Ltd filed Critical Biocon Ltd
Publication of HK1156335A1 publication Critical patent/HK1156335A1/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
    • C08G65/32—Polymers modified by chemical after-treatment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/765—Polymers containing oxygen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/46—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with hetero atoms directly attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
    • C08G65/32—Polymers modified by chemical after-treatment
    • C08G65/329—Polymers modified by chemical after-treatment with organic compounds
    • C08G65/331—Polymers modified by chemical after-treatment with organic compounds containing oxygen
    • C08G65/332—Polymers modified by chemical after-treatment with organic compounds containing oxygen containing carboxyl groups, or halides, or esters thereof
    • C08G65/3322—Polymers modified by chemical after-treatment with organic compounds containing oxygen containing carboxyl groups, or halides, or esters thereof acyclic
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
    • C08G65/32—Polymers modified by chemical after-treatment
    • C08G65/329—Polymers modified by chemical after-treatment with organic compounds
    • C08G65/333—Polymers modified by chemical after-treatment with organic compounds containing nitrogen
    • C08G65/33331—Polymers modified by chemical after-treatment with organic compounds containing nitrogen containing imide group
    • C08G65/33337—Polymers modified by chemical after-treatment with organic compounds containing nitrogen containing imide group cyclic
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G83/00—Macromolecular compounds not provided for in groups C08G2/00 - C08G81/00
HK11110151.1A 2008-07-14 2011-09-26 合成基本上單分散的低聚體混合物的方法 HK1156335A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN1694CH2008 2008-07-14
PCT/IN2008/000545 WO2010007626A1 (en) 2008-07-14 2008-08-28 A method of synthesizing a substantially monodispersed mixture of oligomers

Publications (1)

Publication Number Publication Date
HK1156335A1 true HK1156335A1 (zh) 2012-06-08

Family

ID=41550060

Family Applications (1)

Application Number Title Priority Date Filing Date
HK11110151.1A HK1156335A1 (zh) 2008-07-14 2011-09-26 合成基本上單分散的低聚體混合物的方法

Country Status (14)

Country Link
US (1) US9040723B2 (zh)
EP (1) EP2300514B1 (zh)
JP (1) JP5480257B2 (zh)
KR (1) KR101311597B1 (zh)
CN (1) CN102099397B (zh)
BR (1) BRPI0823084B1 (zh)
DK (1) DK2300514T3 (zh)
ES (1) ES2572891T3 (zh)
HK (1) HK1156335A1 (zh)
IL (1) IL210598A (zh)
MY (1) MY155612A (zh)
PL (1) PL2300514T3 (zh)
PT (1) PT2300514E (zh)
WO (1) WO2010007626A1 (zh)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
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EP2512492A1 (en) 2009-12-14 2012-10-24 University of Massachusetts Methods of inhibiting cataracts and presbyopia
US8993614B2 (en) 2012-03-15 2015-03-31 F. Hoffmann-La Roche Ag Substituted pyrrolidine-2-carboxamides
US9353150B2 (en) 2012-12-04 2016-05-31 Massachusetts Institute Of Technology Substituted pyrazino[1′,2′:1 ,5]pyrrolo[2,3-b]-indole-1,4-diones for cancer treatment
PE20151747A1 (es) 2013-03-14 2015-12-18 Univ Massachusetts Metodo para inhibir cataratas y presbicia
SG11201803606XA (en) * 2015-11-13 2018-05-30 Univ Massachusetts Bifunctional molecules containing peg for use in inhibiting cataracts and presbyopia
WO2017197045A1 (en) 2016-05-11 2017-11-16 Movassaghi Mohammad Convergent and enantioselective total synthesis of communesin analogs
US11932650B2 (en) 2017-05-11 2024-03-19 Massachusetts Institute Of Technology Potent agelastatin derivatives as modulators for cancer invasion and metastasis
US10640508B2 (en) 2017-10-13 2020-05-05 Massachusetts Institute Of Technology Diazene directed modular synthesis of compounds with quaternary carbon centers
CN109179838A (zh) * 2018-10-11 2019-01-11 凯莱英生命科学技术(天津)有限公司 含三乙胺的dmf废水的处理方法
WO2020247054A1 (en) 2019-06-05 2020-12-10 Massachusetts Institute Of Technology Compounds, conjugates, and compositions of epipolythiodiketopiperazines and polythiodiketopiperazines and uses thereof

Family Cites Families (15)

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Publication number Priority date Publication date Assignee Title
AU575038B2 (en) * 1983-01-28 1988-07-21 Fujisawa Pharmaceutical Co., Ltd. Aminoglycoside derivatives, eg 2'n-palmitoyl-kasugamycin
US4980482A (en) * 1988-01-19 1990-12-25 The Dow Chemical Company Process for the preparation of N-maleoyl activated esters of amino acids
DE69033192T3 (de) * 1989-04-19 2004-05-19 Enzon, Inc. Aktive karbonate von polyalkylenoxyden zur modifizierung von polypeptiden
US5672662A (en) * 1995-07-07 1997-09-30 Shearwater Polymers, Inc. Poly(ethylene glycol) and related polymers monosubstituted with propionic or butanoic acids and functional derivatives thereof for biotechnical applications
US6703381B1 (en) * 1998-08-14 2004-03-09 Nobex Corporation Methods for delivery therapeutic compounds across the blood-brain barrier
US7060675B2 (en) * 2001-02-15 2006-06-13 Nobex Corporation Methods of treating diabetes mellitus
US6828297B2 (en) * 2001-06-04 2004-12-07 Nobex Corporation Mixtures of insulin drug-oligomer conjugates comprising polyalkylene glycol, uses thereof, and methods of making same
US6835802B2 (en) * 2001-06-04 2004-12-28 Nobex Corporation Methods of synthesizing substantially monodispersed mixtures of polymers having polyethylene glycol moieties
US6913903B2 (en) * 2001-09-07 2005-07-05 Nobex Corporation Methods of synthesizing insulin polypeptide-oligomer conjugates, and proinsulin polypeptide-oligomer conjugates and methods of synthesizing same
WO2003049699A2 (en) * 2001-12-11 2003-06-19 Sun Bio, Inc. Novel monofunctional polyethylene glycol aldehydes
RU2005130172A (ru) * 2003-02-28 2006-03-20 Алза Корпорейшн (Us) Бus Липосомные композиции для уменьшения активизации комплемента, вызванной липосомами
MXPA05011125A (es) 2003-04-17 2005-12-14 Toyama Chemical Co Ltd Remedio preventivo para enfermedades del nervio retiniano que contienen derivados de eter de alquilo o sales de los mismos.
WO2005025498A2 (en) * 2003-09-08 2005-03-24 Corus Pharma Substituted acetanilides and benzamides for the treatment of asthma and pulmonary inflammation
EP1756173B1 (en) * 2004-01-21 2019-04-03 Nektar Therapeutics Method of preparing propionic acid-terminated polymers
CA2580313C (en) * 2004-07-19 2016-03-15 Biocon Limited Insulin-oligomer conjugates, formulations and uses thereof

Also Published As

Publication number Publication date
EP2300514A4 (en) 2012-12-12
CN102099397B (zh) 2012-12-12
EP2300514A1 (en) 2011-03-30
WO2010007626A1 (en) 2010-01-21
US20110118480A1 (en) 2011-05-19
IL210598A (en) 2014-06-30
JP2011528032A (ja) 2011-11-10
KR20110040916A (ko) 2011-04-20
JP5480257B2 (ja) 2014-04-23
MY155612A (en) 2015-11-13
US9040723B2 (en) 2015-05-26
KR101311597B1 (ko) 2013-09-26
ES2572891T3 (es) 2016-06-02
CN102099397A (zh) 2011-06-15
DK2300514T3 (en) 2016-06-27
EP2300514B1 (en) 2016-03-23
IL210598A0 (en) 2011-03-31
PT2300514E (pt) 2016-06-20
BRPI0823084B1 (pt) 2019-07-16
PL2300514T3 (pl) 2016-09-30
BRPI0823084A2 (pt) 2015-06-16

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20220826