HK1155744A1 - Isoxazole derivatives and their use as metabotropic glutamate receptor potentiators - Google Patents

Isoxazole derivatives and their use as metabotropic glutamate receptor potentiators

Info

Publication number
HK1155744A1
HK1155744A1 HK11110043.3A HK11110043A HK1155744A1 HK 1155744 A1 HK1155744 A1 HK 1155744A1 HK 11110043 A HK11110043 A HK 11110043A HK 1155744 A1 HK1155744 A1 HK 1155744A1
Authority
HK
Hong Kong
Prior art keywords
glutamate receptor
metabotropic glutamate
isoxazole derivatives
receptor potentiators
potentiators
Prior art date
Application number
HK11110043.3A
Other languages
English (en)
Chinese (zh)
Inventor
Joseph Cacciola
James Empfield
James Folmer
Angela M Hunter
Scott Throner
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of HK1155744A1 publication Critical patent/HK1155744A1/xx

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    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/08—Wound clamps or clips, i.e. not or only partly penetrating the tissue ; Devices for bringing together the edges of a wound
    • A61B17/083—Clips, e.g. resilient
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    • A61B17/08—Wound clamps or clips, i.e. not or only partly penetrating the tissue ; Devices for bringing together the edges of a wound
    • A61B17/085—Wound clamps or clips, i.e. not or only partly penetrating the tissue ; Devices for bringing together the edges of a wound with adhesive layer
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    • A61B17/10—Surgical instruments, devices or methods, e.g. tourniquets for applying or removing wound clamps, e.g. containing only one clamp or staple; Wound clamp magazines
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    • A61B17/10—Surgical instruments, devices or methods, e.g. tourniquets for applying or removing wound clamps, e.g. containing only one clamp or staple; Wound clamp magazines
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

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  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Surgery (AREA)
  • Neurosurgery (AREA)
  • Heart & Thoracic Surgery (AREA)
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  • Urology & Nephrology (AREA)
  • Psychology (AREA)
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  • Hematology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Dermatology (AREA)
  • Diabetes (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Otolaryngology (AREA)
  • Anesthesiology (AREA)
  • Rheumatology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HK11110043.3A 2008-06-06 2011-09-23 Isoxazole derivatives and their use as metabotropic glutamate receptor potentiators HK1155744A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US5948508P 2008-06-06 2008-06-06
PCT/SE2009/050682 WO2009148403A1 (fr) 2008-06-06 2009-06-08 Dérivés d'isoxazole et leur utilisation en tant que potentialisateurs du récepteur métabotropique au glutamate

Publications (1)

Publication Number Publication Date
HK1155744A1 true HK1155744A1 (en) 2012-05-25

Family

ID=41398335

Family Applications (2)

Application Number Title Priority Date Filing Date
HK11110043.3A HK1155744A1 (en) 2008-06-06 2011-09-23 Isoxazole derivatives and their use as metabotropic glutamate receptor potentiators
HK15101607.6A HK1201255A1 (en) 2008-06-06 2015-02-13 Use of an isoxazole derivative for the treatment of withdrawal symptoms

Family Applications After (1)

Application Number Title Priority Date Filing Date
HK15101607.6A HK1201255A1 (en) 2008-06-06 2015-02-13 Use of an isoxazole derivative for the treatment of withdrawal symptoms

Country Status (40)

Country Link
US (4) US7790760B2 (fr)
EP (2) EP2303872B1 (fr)
JP (2) JP5476371B2 (fr)
KR (1) KR20110020797A (fr)
CN (1) CN102105466B (fr)
AR (1) AR072016A1 (fr)
AU (1) AU2009255784B2 (fr)
BR (1) BRPI0913585A2 (fr)
CA (1) CA2726925A1 (fr)
CL (1) CL2010001348A1 (fr)
CO (1) CO6321239A2 (fr)
CR (1) CR11826A (fr)
CU (1) CU23883B1 (fr)
CY (1) CY1115301T1 (fr)
DK (1) DK2303872T3 (fr)
DO (1) DOP2010000375A (fr)
EA (2) EA201300342A1 (fr)
EC (1) ECSP10010662A (fr)
ES (1) ES2469837T3 (fr)
GT (1) GT201000342A (fr)
HK (2) HK1155744A1 (fr)
HN (1) HN2010002582A (fr)
HR (1) HRP20140451T1 (fr)
IL (1) IL209622A0 (fr)
MX (1) MX2010012949A (fr)
MY (1) MY156552A (fr)
NI (3) NI201000209A (fr)
NZ (1) NZ590344A (fr)
PE (1) PE20110028A1 (fr)
PL (1) PL2303872T3 (fr)
PT (1) PT2303872E (fr)
RS (1) RS53392B (fr)
SA (1) SA109300358B1 (fr)
SI (1) SI2303872T1 (fr)
SV (1) SV2010003751A (fr)
TW (3) TW201514173A (fr)
UA (1) UA107649C2 (fr)
UY (1) UY31870A (fr)
WO (1) WO2009148403A1 (fr)
ZA (1) ZA201008611B (fr)

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JO3367B1 (ar) 2013-09-06 2019-03-13 Janssen Pharmaceutica Nv مركبات 2،1، 4- ثلاثي زولو [3،4-a] بيريدين واستخدامها بصفة منظمات تفارغية موجبة لمستقبلات ميجلور 2
ME03518B (fr) 2014-01-21 2020-04-20 Janssen Pharmaceutica Nv Combinaisons comprenant des modulateurs allostériques positifs de sous-type 2 de récepteurs glutamatergiques métabotropes et leur utilisation
SI3096790T1 (sl) 2014-01-21 2019-11-29 Janssen Pharmaceutica Nv Kombinacije, ki vsebujejo pozitivne aleostrične modulatorje ali ortosterične agoniste metabotropnega glutamatergičnega receptorja podtipa 2 in njihova uporaba
EP3129345B1 (fr) 2014-04-06 2023-03-15 Sanford-Burnham Medical Research Institute Modulateurs allostériques positifs (pam) du récepteur métabotropique du glutamate et leurs utilisations
KR101663662B1 (ko) * 2015-06-17 2016-10-14 한국과학기술연구원 대사성 글루타메이트 수용체 1에 활성을 지닌 신규 아릴 아이소옥사졸 유도체
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