HK1154382A1 - Triazole derivatives useful for the treatment of diseases - Google Patents

Triazole derivatives useful for the treatment of diseases

Info

Publication number
HK1154382A1
HK1154382A1 HK11108477.2A HK11108477A HK1154382A1 HK 1154382 A1 HK1154382 A1 HK 1154382A1 HK 11108477 A HK11108477 A HK 11108477A HK 1154382 A1 HK1154382 A1 HK 1154382A1
Authority
HK
Hong Kong
Prior art keywords
diseases
treatment
triazole derivatives
derivatives useful
useful
Prior art date
Application number
HK11108477.2A
Other languages
English (en)
Inventor
Jones Lyn Howard
Roberts Dannielle Frances
Strang Ross Sinclair
Original Assignee
Pfizer Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Ltd filed Critical Pfizer Ltd
Publication of HK1154382A1 publication Critical patent/HK1154382A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/081,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41961,2,4-Triazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/04Drugs for disorders of the respiratory system for throat disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/16Central respiratory analeptics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Otolaryngology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
HK11108477.2A 2008-07-11 2011-08-12 Triazole derivatives useful for the treatment of diseases HK1154382A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US7983708P 2008-07-11 2008-07-11
PCT/IB2009/052986 WO2010004517A1 (en) 2008-07-11 2009-07-09 Triazole derivatives useful for the treatment of diseases

Publications (1)

Publication Number Publication Date
HK1154382A1 true HK1154382A1 (en) 2012-04-20

Family

ID=41078162

Family Applications (1)

Application Number Title Priority Date Filing Date
HK11108477.2A HK1154382A1 (en) 2008-07-11 2011-08-12 Triazole derivatives useful for the treatment of diseases

Country Status (30)

Country Link
US (1) US8263623B2 (es)
EP (1) EP2300443B1 (es)
JP (1) JP5608162B2 (es)
KR (1) KR101235962B1 (es)
CN (1) CN102089290B (es)
AP (1) AP2010005508A0 (es)
AR (1) AR072488A1 (es)
AU (1) AU2009269610B2 (es)
BR (1) BRPI0915897A2 (es)
CA (1) CA2726686C (es)
CO (1) CO6321248A2 (es)
CR (1) CR11818A (es)
DK (1) DK2300443T3 (es)
DO (1) DOP2011000010A (es)
EA (1) EA201001821A1 (es)
EC (1) ECSP11010754A (es)
ES (1) ES2398428T3 (es)
HK (1) HK1154382A1 (es)
IL (1) IL209730A (es)
MA (1) MA32466B1 (es)
MX (1) MX2011000352A (es)
NI (1) NI201100006A (es)
NZ (1) NZ589613A (es)
PE (1) PE20110151A1 (es)
SV (1) SV2011003802A (es)
TW (1) TW201006822A (es)
UA (1) UA99524C2 (es)
UY (1) UY31976A (es)
WO (1) WO2010004517A1 (es)
ZA (1) ZA201100534B (es)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UY33373A (es) 2010-05-10 2011-12-30 Gilead Sciences Inc ?Compuestos de pirazolopiridina bifuncionales, su uso en terapia y composiciones que los comprenden?.
NZ603136A (en) * 2010-05-10 2014-11-28 Gilead Sciences Inc Bifunctional quinoline derivatives
ITRM20110083U1 (it) 2010-05-13 2011-11-14 De La Cruz Jose Antonio Freire Piastra per la costruzione di carrelli per aeroplani
EP2386555A1 (en) 2010-05-13 2011-11-16 Almirall, S.A. New cyclohexylamine derivatives having beta2 adrenergic agonist and m3 muscarinic antagonist activities
KR101840852B1 (ko) 2011-10-10 2018-03-22 삼성전자주식회사 모바일 장치의 표면 온도 관리 방법 및 멀티칩 패키지의 메모리 열관리 방법
KR101857529B1 (ko) 2011-11-08 2018-05-15 삼성전자주식회사 비휘발성 메모리 장치 및 그것의 구동 방법
EP2592078A1 (en) 2011-11-11 2013-05-15 Almirall, S.A. New cyclohexylamine derivatives having beta2 adrenergic agonist and M3 muscarinic antagonist activities
DE102012111829A1 (de) 2011-12-06 2013-06-06 Samsung Electronics Co., Ltd. Speichersysteme und Blockkopierverfahren davon
KR101859646B1 (ko) 2011-12-16 2018-05-18 삼성전자주식회사 보안 데이터를 보호하는 메모리 장치 및 보안 데이터를 이용한 데이터 보호 방법
DE102013100596B4 (de) 2012-01-27 2023-09-07 Samsung Electronics Co. Ltd. Nichtflüchtiges Speichersystem mit Programmier- und Löschverfahren und Blockverwaltungsverfahren
KR101903440B1 (ko) 2012-02-21 2018-10-02 삼성전자주식회사 비휘발성 메모리 장치 및 그것의 접지 선택 트랜지스터의 문턱전압 조절 방법
KR101996004B1 (ko) 2012-05-29 2019-07-03 삼성전자주식회사 비휘발성 메모리 장치의 프로그램 방법 및 그것의 메모리 시스템
DE102013105356A1 (de) 2012-05-29 2013-12-05 Samsung Electronics Co., Ltd. Verfahren zum Betreiben von nichtflüchtigen Speichervorrichtungen, die effiziente Fehlererkennung unterstützen
KR102000634B1 (ko) 2012-06-07 2019-07-16 삼성전자주식회사 비휘발성 메모리 장치 및 그것의 소거 방법
KR102025263B1 (ko) 2012-10-05 2019-09-25 삼성전자주식회사 메모리 시스템 및 그것의 읽기 교정 방법
KR102025251B1 (ko) 2012-10-31 2019-09-25 삼성전자주식회사 메모리 시스템 및 그것의 프로그램 방법
ES2750523T3 (es) 2012-12-18 2020-03-26 Almirall Sa Derivados de ciclohexil y quinuclidinil carbamato que tienen actividades de agonista beta2 adrenérgicos y antagonistas muscarínicos M3
TWI643853B (zh) 2013-02-27 2018-12-11 阿爾米雷爾有限公司 同時具有β2腎上腺素受體促效劑和M3毒蕈鹼受體拮抗劑活性之2-氨基-1-羥乙基-8-羥基喹啉-2(1H)-酮衍生物之鹽類
KR102068342B1 (ko) 2013-03-07 2020-01-20 삼성전자주식회사 메모리 제어기 및 그것을 포함하는 메모리 시스템
TWI641373B (zh) 2013-07-25 2018-11-21 阿爾米雷爾有限公司 具有蕈毒鹼受體拮抗劑和β2腎上腺素受體促效劑二者之活性的2-胺基-1-羥乙基-8-羥基喹啉-2(1H)-酮衍生物之鹽
TW201517906A (zh) 2013-07-25 2015-05-16 Almirall Sa 含有maba化合物和皮質類固醇之組合
KR102187643B1 (ko) 2013-12-04 2020-12-08 삼성전자주식회사 메모리 시스템 및 그것을 포함하는 유저 장치
TW201617343A (zh) 2014-09-26 2016-05-16 阿爾米雷爾有限公司 具有β2腎上腺素促效劑及M3蕈毒拮抗劑活性之新穎雙環衍生物
CA3047023C (en) 2016-12-14 2022-05-31 Beijing Showby Pharmaceutical Co., Ltd. Class of bifunctional compounds with quaternary ammonium salt structure
CN107194205B (zh) * 2017-05-31 2020-11-24 浙江大学 具有杀菌活性的jak2激酶抑制剂及其虚拟筛选方法
NZ762856A (en) 2017-10-05 2020-07-31 Fulcrum Therapeutics Inc P38 kinase inhibitors reduce dux4 and downstream gene expression for the treatment of fshd
US10342786B2 (en) 2017-10-05 2019-07-09 Fulcrum Therapeutics, Inc. P38 kinase inhibitors reduce DUX4 and downstream gene expression for the treatment of FSHD

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996033973A1 (fr) 1995-04-28 1996-10-31 Banyu Pharmaceutical Co., Ltd. Derives disubstitues en position 1,4 de piperidine
GB9603755D0 (en) 1996-02-22 1996-04-24 Pfizer Ltd Therapeutic agents
ES2165768B1 (es) 1999-07-14 2003-04-01 Almirall Prodesfarma Sa Nuevos derivados de quinuclidina y composiciones farmaceuticas que los contienen.
HUP0303524A3 (en) 2000-12-28 2008-03-28 Almirall Ag Novel quinuclidine derivatives, process for their preparation and medicinal compositions containing the same and their use
DE10200943A1 (de) 2002-01-12 2003-07-24 Boehringer Ingelheim Pharma Verfahren zur Herstellung von Scopinestern
WO2004052857A1 (en) 2002-12-10 2004-06-24 Ranbaxy Laboratories Limited 3,6-disubstituted azabicyclo [3.1.0] hexane derivatives as muscarinic receptor antagonists
PE20040950A1 (es) 2003-02-14 2005-01-01 Theravance Inc DERIVADOS DE BIFENILO COMO AGONISTAS DE LOS RECEPTORES ADRENERGICOS ß2 Y COMO ANTAGONISTAS DE LOS RECEPTORES MUSCARINICOS
CN101239968B (zh) * 2003-02-14 2011-07-20 施万制药 联苯衍生物
EP1460064A1 (en) 2003-03-14 2004-09-22 Pfizer Limited Indole-2-carboxamide derivatives useful as beta-2 agonists
US7317102B2 (en) 2003-04-01 2008-01-08 Theravance, Inc. Diarylmethyl and related compounds
EP1626970B1 (en) 2003-05-28 2009-07-08 Theravance, Inc. Azabicycloalkane compounds as muscarinic receptor antagonists
ES2289691T3 (es) 2004-01-22 2008-02-01 Pfizer, Inc. Derivados de sulfonamida para el tratamiento de enfermedades.
BRPI0507877A (pt) 2004-03-23 2007-07-24 Pfizer derivados de formamida, composição farmacêutica, uso dos mesmos e combinação
US7538141B2 (en) 2004-03-23 2009-05-26 Alan Daniel Brown Compounds for the treatment of diseases
WO2006023460A2 (en) * 2004-08-16 2006-03-02 Theravance, Inc. COMPOUNDS HAVING β2 ADRENERGIC RECEPTOR AGONIST AND MUSCARINIC RECEPTOR ANTAGONIST ACTIVITY
GB0424284D0 (en) 2004-11-02 2004-12-01 Novartis Ag Organic compounds
GB0516313D0 (en) 2005-08-08 2005-09-14 Argenta Discovery Ltd Azole derivatives and their uses
TW200745084A (en) * 2006-03-08 2007-12-16 Astrazeneca Ab Novel compounds
JP2010501533A (ja) 2006-08-21 2010-01-21 アージェンタ ディスカバリー リミテッド M3レセプター調節物質として有用な窒素含有複素環化合物

Also Published As

Publication number Publication date
KR101235962B1 (ko) 2013-02-21
ES2398428T3 (es) 2013-03-19
MX2011000352A (es) 2011-02-22
IL209730A0 (en) 2011-02-28
NZ589613A (en) 2012-06-29
AU2009269610A1 (en) 2010-01-14
CA2726686A1 (en) 2010-01-14
US20100010040A1 (en) 2010-01-14
KR20110018423A (ko) 2011-02-23
JP2011527672A (ja) 2011-11-04
AU2009269610B2 (en) 2012-02-02
UA99524C2 (ru) 2012-08-27
DK2300443T3 (da) 2013-02-18
ECSP11010754A (es) 2011-02-28
DOP2011000010A (es) 2011-01-31
UY31976A (es) 2010-02-26
IL209730A (en) 2013-11-28
AP2010005508A0 (en) 2010-12-31
TW201006822A (en) 2010-02-16
EP2300443A1 (en) 2011-03-30
WO2010004517A1 (en) 2010-01-14
US8263623B2 (en) 2012-09-11
AR072488A1 (es) 2010-09-01
BRPI0915897A2 (pt) 2015-11-03
SV2011003802A (es) 2011-03-23
PE20110151A1 (es) 2011-03-05
ZA201100534B (en) 2011-10-26
CN102089290A (zh) 2011-06-08
MA32466B1 (fr) 2011-07-03
EA201001821A1 (ru) 2011-08-30
CN102089290B (zh) 2013-09-04
JP5608162B2 (ja) 2014-10-15
CA2726686C (en) 2014-03-11
EP2300443B1 (en) 2012-12-12
CR11818A (es) 2011-01-14
NI201100006A (es) 2011-07-20
CO6321248A2 (es) 2011-09-20

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PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20170709