HK1152082A1 - Method of preventing virus:cell fusion by inhibiting the function of the fusion initiation region in rna viruses having class i membrane fusogenic envelope proteins - Google Patents

Method of preventing virus:cell fusion by inhibiting the function of the fusion initiation region in rna viruses having class i membrane fusogenic envelope proteins

Info

Publication number
HK1152082A1
HK1152082A1 HK11106193.9A HK11106193A HK1152082A1 HK 1152082 A1 HK1152082 A1 HK 1152082A1 HK 11106193 A HK11106193 A HK 11106193A HK 1152082 A1 HK1152082 A1 HK 1152082A1
Authority
HK
Hong Kong
Prior art keywords
fusion
present
viruses
class
inhibiting
Prior art date
Application number
HK11106193.9A
Other languages
English (en)
Inventor
Robert F Garry
Russell B Wilson
Original Assignee
Univ Tulane
Autoimmune Technologies Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Tulane, Autoimmune Technologies Llc filed Critical Univ Tulane
Publication of HK1152082A1 publication Critical patent/HK1152082A1/xx

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/162—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/18—Testing for antimicrobial activity of a material
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983—Viruses
    • G01N33/56988—HIV or HTLV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
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    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/10011—Arenaviridae
    • C12N2760/10022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
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    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/14011—Filoviridae
    • C12N2760/14111—Ebolavirus, e.g. Zaire ebolavirus
    • C12N2760/14122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/18011—Paramyxoviridae
    • C12N2760/18411—Morbillivirus, e.g. Measles virus, canine distemper
    • C12N2760/18422—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/18011—Paramyxoviridae
    • C12N2760/18411—Morbillivirus, e.g. Measles virus, canine distemper
    • C12N2760/18433—Use of viral protein as therapeutic agent other than vaccine, e.g. apoptosis inducing or anti-inflammatory
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/20011—Coronaviridae
    • C12N2770/20022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
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  • Gastroenterology & Hepatology (AREA)
  • Wood Science & Technology (AREA)
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  • Veterinary Medicine (AREA)
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  • Microbiology (AREA)
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  • Biotechnology (AREA)
  • Epidemiology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
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  • Cell Biology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
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HK11106193.9A 2003-11-04 2011-06-15 Method of preventing virus:cell fusion by inhibiting the function of the fusion initiation region in rna viruses having class i membrane fusogenic envelope proteins HK1152082A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US51718103P 2003-11-04 2003-11-04

Publications (1)

Publication Number Publication Date
HK1152082A1 true HK1152082A1 (en) 2012-02-17

Family

ID=34572923

Family Applications (6)

Application Number Title Priority Date Filing Date
HK11106200.0A HK1152086A1 (en) 2003-11-04 2011-06-15 Method of preventing virus:cell fusion by inhibiting the function of the fusion initiation region in rna viruses having class i membrane fusogenic envelope proteins
HK11106192.0A HK1152081A1 (en) 2003-11-04 2011-06-15 Method of preventing virus:cell fusion by inhibiting the function of the fusion initiation region in rna viruses having class i membrane fusogenic envelope proteins
HK11106194.8A HK1152083A1 (en) 2003-11-04 2011-06-15 Method of preventing virus:cell fusion by inhibiting the function of the fusion initiation region in rna viruses having class i membrane fusogenic envelope proteins
HK11106193.9A HK1152082A1 (en) 2003-11-04 2011-06-15 Method of preventing virus:cell fusion by inhibiting the function of the fusion initiation region in rna viruses having class i membrane fusogenic envelope proteins
HK11106195.7A HK1152084A1 (en) 2003-11-04 2011-06-15 Method of preventing virus:cell fusion by inhibiting the function of the fusion initiation region in rna viruses having class i membrane fusogenic envelope proteins
HK11106198.4A HK1152085A1 (en) 2003-11-04 2011-06-15 Method of preventing virus:cell fusion by inhibiting the function of the fusion initiation region in rna viruses having class i membrane fusogenic envelope proteins

Family Applications Before (3)

Application Number Title Priority Date Filing Date
HK11106200.0A HK1152086A1 (en) 2003-11-04 2011-06-15 Method of preventing virus:cell fusion by inhibiting the function of the fusion initiation region in rna viruses having class i membrane fusogenic envelope proteins
HK11106192.0A HK1152081A1 (en) 2003-11-04 2011-06-15 Method of preventing virus:cell fusion by inhibiting the function of the fusion initiation region in rna viruses having class i membrane fusogenic envelope proteins
HK11106194.8A HK1152083A1 (en) 2003-11-04 2011-06-15 Method of preventing virus:cell fusion by inhibiting the function of the fusion initiation region in rna viruses having class i membrane fusogenic envelope proteins

Family Applications After (2)

Application Number Title Priority Date Filing Date
HK11106195.7A HK1152084A1 (en) 2003-11-04 2011-06-15 Method of preventing virus:cell fusion by inhibiting the function of the fusion initiation region in rna viruses having class i membrane fusogenic envelope proteins
HK11106198.4A HK1152085A1 (en) 2003-11-04 2011-06-15 Method of preventing virus:cell fusion by inhibiting the function of the fusion initiation region in rna viruses having class i membrane fusogenic envelope proteins

Country Status (13)

Country Link
US (5) US7491793B2 (pt)
EP (7) EP2261374B1 (pt)
JP (1) JP5008398B2 (pt)
AT (1) ATE518967T1 (pt)
AU (2) AU2004288218B2 (pt)
BR (1) BRPI0416187A (pt)
CA (1) CA2544848C (pt)
DK (7) DK2261376T3 (pt)
ES (7) ES2392891T3 (pt)
HK (6) HK1152086A1 (pt)
PL (4) PL2261376T3 (pt)
PT (4) PT2261376E (pt)
WO (1) WO2005044992A2 (pt)

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HK1152083A1 (en) 2012-02-17
DK2261378T3 (da) 2014-01-20
PL1692265T3 (pl) 2011-12-30
EP2261377A2 (en) 2010-12-15
AU2004288218A1 (en) 2005-05-19
PL2261378T3 (pl) 2014-03-31
ES2437858T3 (es) 2014-01-14
PL2261377T3 (pl) 2014-03-31
PT2261376E (pt) 2013-09-23
BRPI0416187A (pt) 2007-01-23
ES2392891T3 (es) 2012-12-14
HK1152085A1 (en) 2012-02-17
CA2544848C (en) 2015-12-29
EP2261378A2 (en) 2010-12-15
EP2261377B1 (en) 2013-10-02
EP2261376B1 (en) 2013-07-10
DK2261377T3 (da) 2014-01-06
WO2005044992A3 (en) 2006-12-07
EP2261374A3 (en) 2011-03-02
EP1692265A4 (en) 2007-08-29
AU2010201046B2 (en) 2013-06-27
EP1692265B1 (en) 2011-08-03
PT2261378E (pt) 2013-12-09
US20140045743A1 (en) 2014-02-13
PT2261377E (pt) 2013-11-29
EP2261380A3 (en) 2011-02-23
CA2544848A1 (en) 2005-05-19
AU2010201046A1 (en) 2010-04-08
EP1692265A2 (en) 2006-08-23
HK1152084A1 (en) 2012-02-17
ES2372633T3 (es) 2012-01-25
EP2261376A2 (en) 2010-12-15
US20120289458A1 (en) 2012-11-15
DK2261374T3 (da) 2012-09-10
EP2261376A3 (en) 2011-02-23
HK1152086A1 (en) 2012-02-17
ES2400456T3 (es) 2013-04-10
JP2007514408A (ja) 2007-06-07
US9056900B2 (en) 2015-06-16
EP2261375A3 (en) 2011-06-22
US7491793B2 (en) 2009-02-17
WO2005044992A2 (en) 2005-05-19
EP2261375B1 (en) 2013-01-23
DK1692265T3 (da) 2011-11-21
EP2261378A3 (en) 2011-06-15
EP2261380A2 (en) 2010-12-15
PT1692265E (pt) 2011-10-11
EP2261377A3 (en) 2011-05-18
ES2425600T3 (es) 2013-10-16
EP2261374B1 (en) 2012-06-06
PL2261376T3 (pl) 2014-04-30
DK2261376T3 (da) 2013-10-07
EP2261375A2 (en) 2010-12-15
JP5008398B2 (ja) 2012-08-22
ES2427847T3 (es) 2013-11-04
US20150239940A1 (en) 2015-08-27
EP2261378B1 (en) 2013-10-09
EP2261380B1 (en) 2013-07-17
ES2435941T3 (es) 2013-12-26
AU2004288218B2 (en) 2009-12-24
DK2261375T3 (da) 2013-04-22
US8598116B2 (en) 2013-12-03
US9725487B2 (en) 2017-08-08
US20060280754A1 (en) 2006-12-14
ATE518967T1 (de) 2011-08-15
EP2261374A2 (en) 2010-12-15
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US20090264362A1 (en) 2009-10-22
DK2261380T3 (da) 2013-10-07

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