PT1692265E - Método de prevenção de infecções virais: fusão celular por meio de inibição da função da região de partida de fusão em vírus arn com proteínas de envelope fusogénicas de membrana de classe i - Google Patents

Método de prevenção de infecções virais: fusão celular por meio de inibição da função da região de partida de fusão em vírus arn com proteínas de envelope fusogénicas de membrana de classe i Download PDF

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Publication number
PT1692265E
PT1692265E PT04810256T PT04810256T PT1692265E PT 1692265 E PT1692265 E PT 1692265E PT 04810256 T PT04810256 T PT 04810256T PT 04810256 T PT04810256 T PT 04810256T PT 1692265 E PT1692265 E PT 1692265E
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PT
Portugal
Prior art keywords
fusion
present
viruses
class
inhibiting
Prior art date
Application number
PT04810256T
Other languages
English (en)
Inventor
Robert F Garry
Russell B Wilson
Original Assignee
Univ Tulane
Autoimmune Technologies Llc
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Publication date
Application filed by Univ Tulane, Autoimmune Technologies Llc filed Critical Univ Tulane
Publication of PT1692265E publication Critical patent/PT1692265E/pt

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/162—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/18—Testing for antimicrobial activity of a material
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983—Viruses
    • G01N33/56988—HIV or HTLV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/10011—Arenaviridae
    • C12N2760/10022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/14011—Filoviridae
    • C12N2760/14111—Ebolavirus, e.g. Zaire ebolavirus
    • C12N2760/14122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/18011—Paramyxoviridae
    • C12N2760/18411—Morbillivirus, e.g. Measles virus, canine distemper
    • C12N2760/18422—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/18011—Paramyxoviridae
    • C12N2760/18411—Morbillivirus, e.g. Measles virus, canine distemper
    • C12N2760/18433—Use of viral protein as therapeutic agent other than vaccine, e.g. apoptosis inducing or anti-inflammatory
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/20011—Coronaviridae
    • C12N2770/20022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
PT04810256T 2003-11-04 2004-11-03 Método de prevenção de infecções virais: fusão celular por meio de inibição da função da região de partida de fusão em vírus arn com proteínas de envelope fusogénicas de membrana de classe i PT1692265E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US51718103P 2003-11-04 2003-11-04

Publications (1)

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PT1692265E true PT1692265E (pt) 2011-10-11

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Family Applications (4)

Application Number Title Priority Date Filing Date
PT101820496T PT2261377E (pt) 2003-11-04 2004-11-03 Método para prevenir a fusão vírus:células inibindo a função da região de iniciação de fusão em vírus de rna tendo proteínas do invólucro fusogénicas de membrana de classe
PT101820561T PT2261378E (pt) 2003-11-04 2004-11-03 Método de prevenção da fusão vírus:células através da inibição da função da região de iniciação de fusão em vírus de rna contendo proteínas do invólucro fusogénico de membrana de classe i
PT04810256T PT1692265E (pt) 2003-11-04 2004-11-03 Método de prevenção de infecções virais: fusão celular por meio de inibição da função da região de partida de fusão em vírus arn com proteínas de envelope fusogénicas de membrana de classe i
PT101820405T PT2261376E (pt) 2003-11-04 2004-11-03 Método para prevenir a fusão vírus:células inibindo a função da região de iniciação de fusão em vírus de rna tendo proteínas do invólucro fusogénicas de membrana de classe i

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PT101820496T PT2261377E (pt) 2003-11-04 2004-11-03 Método para prevenir a fusão vírus:células inibindo a função da região de iniciação de fusão em vírus de rna tendo proteínas do invólucro fusogénicas de membrana de classe
PT101820561T PT2261378E (pt) 2003-11-04 2004-11-03 Método de prevenção da fusão vírus:células através da inibição da função da região de iniciação de fusão em vírus de rna contendo proteínas do invólucro fusogénico de membrana de classe i

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PT101820405T PT2261376E (pt) 2003-11-04 2004-11-03 Método para prevenir a fusão vírus:células inibindo a função da região de iniciação de fusão em vírus de rna tendo proteínas do invólucro fusogénicas de membrana de classe i

Country Status (13)

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US (5) US7491793B2 (pt)
EP (7) EP2261375B1 (pt)
JP (1) JP5008398B2 (pt)
AT (1) ATE518967T1 (pt)
AU (2) AU2004288218B2 (pt)
BR (1) BRPI0416187A (pt)
CA (1) CA2544848C (pt)
DK (7) DK2261374T3 (pt)
ES (7) ES2400456T3 (pt)
HK (6) HK1152082A1 (pt)
PL (4) PL2261377T3 (pt)
PT (4) PT2261377E (pt)
WO (1) WO2005044992A2 (pt)

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AU2004288218A1 (en) 2005-05-19
ES2372633T3 (es) 2012-01-25
ES2435941T3 (es) 2013-12-26
HK1152082A1 (en) 2012-02-17
PT2261377E (pt) 2013-11-29
AU2010201046A1 (en) 2010-04-08
WO2005044992A2 (en) 2005-05-19
DK2261380T3 (da) 2013-10-07
JP5008398B2 (ja) 2012-08-22
BRPI0416187A (pt) 2007-01-23
DK1692265T3 (da) 2011-11-21
ES2425600T3 (es) 2013-10-16
PT2261376E (pt) 2013-09-23
EP2261375B1 (en) 2013-01-23
EP2261374A2 (en) 2010-12-15
EP2261378A3 (en) 2011-06-15
PL2261376T3 (pl) 2014-04-30
CA2544848A1 (en) 2005-05-19
EP2261375A2 (en) 2010-12-15
EP2261377B1 (en) 2013-10-02
ES2437858T3 (es) 2014-01-14
HK1152086A1 (en) 2012-02-17
ES2400456T3 (es) 2013-04-10
JP2007514408A (ja) 2007-06-07
ATE518967T1 (de) 2011-08-15
EP2261378A2 (en) 2010-12-15
CA2544848C (en) 2015-12-29
US20060280754A1 (en) 2006-12-14
US9056900B2 (en) 2015-06-16
EP2261376A2 (en) 2010-12-15
HK1152083A1 (en) 2012-02-17
US20150239940A1 (en) 2015-08-27
EP1692265B1 (en) 2011-08-03
EP1692265A2 (en) 2006-08-23
PL2261378T3 (pl) 2014-03-31
EP2261380A2 (en) 2010-12-15
DK2261378T3 (da) 2014-01-20
PL1692265T3 (pl) 2011-12-30
PT2261378E (pt) 2013-12-09
HK1152084A1 (en) 2012-02-17
AU2004288218B2 (en) 2009-12-24
EP2261380B1 (en) 2013-07-17
AU2010201046B2 (en) 2013-06-27
EP1692265A4 (en) 2007-08-29
WO2005044992A3 (en) 2006-12-07
US9725487B2 (en) 2017-08-08
US7491793B2 (en) 2009-02-17
EP2261375A3 (en) 2011-06-22
EP2261378B1 (en) 2013-10-09
EP2261380A3 (en) 2011-02-23
EP2261374A3 (en) 2011-03-02
DK2261377T3 (da) 2014-01-06
PL2261377T3 (pl) 2014-03-31
EP2261376A3 (en) 2011-02-23
DK2261374T3 (da) 2012-09-10
US20120289458A1 (en) 2012-11-15
US20090264362A1 (en) 2009-10-22
EP2261377A3 (en) 2011-05-18
HK1152085A1 (en) 2012-02-17
EP2261377A2 (en) 2010-12-15
US8598116B2 (en) 2013-12-03
ES2427847T3 (es) 2013-11-04
DK2261376T3 (da) 2013-10-07
ES2392891T3 (es) 2012-12-14
EP2261374B1 (en) 2012-06-06
EP2261376B1 (en) 2013-07-10
HK1152081A1 (en) 2012-02-17
DK2261375T3 (da) 2013-04-22
US20140045743A1 (en) 2014-02-13

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