HK1150995A1 - High gradient magnet separation of biological material - Google Patents

High gradient magnet separation of biological material

Info

Publication number
HK1150995A1
HK1150995A1 HK11105100.3A HK11105100A HK1150995A1 HK 1150995 A1 HK1150995 A1 HK 1150995A1 HK 11105100 A HK11105100 A HK 11105100A HK 1150995 A1 HK1150995 A1 HK 1150995A1
Authority
HK
Hong Kong
Prior art keywords
ferromagnetic matrix
biological material
separation column
buffer solution
high gradient
Prior art date
Application number
HK11105100.3A
Other languages
English (en)
Chinese (zh)
Inventor
Sebastian Chakrit Bhakdi
Prida Malasit
Original Assignee
億克斯-澤爾生物科技有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 億克斯-澤爾生物科技有限公司 filed Critical 億克斯-澤爾生物科技有限公司
Publication of HK1150995A1 publication Critical patent/HK1150995A1/xx

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B03SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03CMAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C1/00Magnetic separation
    • B03C1/002High gradient magnetic separation
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B03SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03CMAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C1/00Magnetic separation
    • B03C1/005Pretreatment specially adapted for magnetic separation
    • B03C1/01Pretreatment specially adapted for magnetic separation by addition of magnetic adjuvants
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B03SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03CMAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C1/00Magnetic separation
    • B03C1/02Magnetic separation acting directly on the substance being separated
    • B03C1/025High gradient magnetic separators
    • B03C1/031Component parts; Auxiliary operations
    • B03C1/032Matrix cleaning systems
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B03SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03CMAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C1/00Magnetic separation
    • B03C1/02Magnetic separation acting directly on the substance being separated
    • B03C1/025High gradient magnetic separators
    • B03C1/031Component parts; Auxiliary operations
    • B03C1/033Component parts; Auxiliary operations characterised by the magnetic circuit
    • B03C1/0335Component parts; Auxiliary operations characterised by the magnetic circuit using coils
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B03SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03CMAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C1/00Magnetic separation
    • B03C1/02Magnetic separation acting directly on the substance being separated
    • B03C1/025High gradient magnetic separators
    • B03C1/031Component parts; Auxiliary operations
    • B03C1/033Component parts; Auxiliary operations characterised by the magnetic circuit
    • B03C1/034Component parts; Auxiliary operations characterised by the magnetic circuit characterised by the matrix elements
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B03SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03CMAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C1/00Magnetic separation
    • B03C1/02Magnetic separation acting directly on the substance being separated
    • B03C1/28Magnetic plugs and dipsticks
    • B03C1/288Magnetic plugs and dipsticks disposed at the outer circumference of a recipient
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N13/00Treatment of microorganisms or enzymes with electrical or wave energy, e.g. magnetism, sonic waves
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B03SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03CMAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C2201/00Details of magnetic or electrostatic separation
    • B03C2201/18Magnetic separation whereby the particles are suspended in a liquid
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B03SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03CMAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C2201/00Details of magnetic or electrostatic separation
    • B03C2201/26Details of magnetic or electrostatic separation for use in medical applications

Landscapes

  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
HK11105100.3A 2007-09-11 2011-05-23 High gradient magnet separation of biological material HK1150995A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102007043281A DE102007043281A1 (de) 2007-09-11 2007-09-11 Vorrichtung, Materialien und Verfahren zur Hochgradientenmagnetseparation biologischen Materials
PCT/EP2008/061170 WO2009033947A2 (de) 2007-09-11 2008-08-26 Hochgradientenmagnetseparation biologischen materials

Publications (1)

Publication Number Publication Date
HK1150995A1 true HK1150995A1 (en) 2012-01-20

Family

ID=40343626

Family Applications (1)

Application Number Title Priority Date Filing Date
HK11105100.3A HK1150995A1 (en) 2007-09-11 2011-05-23 High gradient magnet separation of biological material

Country Status (11)

Country Link
US (2) US20100273230A1 (ja)
EP (1) EP2190585B1 (ja)
JP (1) JP4913244B2 (ja)
CN (1) CN101977692B (ja)
AT (1) ATE508800T1 (ja)
CA (1) CA2698699C (ja)
DE (1) DE102007043281A1 (ja)
DK (1) DK2190585T3 (ja)
ES (1) ES2366074T3 (ja)
HK (1) HK1150995A1 (ja)
WO (1) WO2009033947A2 (ja)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102008045759A1 (de) * 2008-09-04 2010-03-25 Forschungszentrum Jülich GmbH Verfahren und Vorrichtung zur Sortierung von Partikeln nach deren Magnetisierbarkeit
ES2690784T3 (es) * 2011-04-27 2018-11-22 Becton Dickinson And Company Dispositivos y métodos para separar fragmentos etiquetados magnéticamente en una muestra
DE102011080945A1 (de) * 2011-08-15 2013-02-21 Siemens Aktiengesellschaft Dynamische Zustandsbestimmung von Analyten mittels magnetischer Durchflussmessung
IN2014DN06822A (ja) 2012-08-31 2015-05-22 Toshiba Kk
JP6041280B2 (ja) * 2013-06-28 2016-12-07 国立研究開発法人産業技術総合研究所 磁選機用マトリックス及び磁選機
CN105170316B (zh) * 2015-10-09 2017-03-22 北京科技大学 一种利用磁化力实现均相混合液体的分子/离子级分离装置及方法
CN109752224B (zh) * 2017-11-06 2023-11-28 广州禾信仪器股份有限公司 浓缩装置及气动聚焦系统
CN108287236B (zh) * 2017-11-24 2020-03-13 中国农业大学 一种基于高梯度磁分离和量子点的荧光生物传感器及其应用
CN108296013B (zh) * 2018-03-02 2023-11-14 浙江大学 一种超顺磁纳米微粒的分离装置及其应用
EP3693739A1 (de) 2019-02-06 2020-08-12 Stefan Schreier Verfahren und vorrichtung zur isolierung von gewünschten zellen aus einer probe nicht-magnetischer biologischer materialien
DE102022200663A1 (de) 2022-01-21 2023-07-27 Robert Bosch Gesellschaft mit beschränkter Haftung Mikrofluidische Vorrichtung und Verfahren zu ihrem Betrieb
US20240011014A1 (en) * 2022-06-30 2024-01-11 Illumina, Inc. In-tip magnetic-based magnetic bead processing

Family Cites Families (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3676337A (en) 1970-07-09 1972-07-11 Massachusetts Inst Technology Process for magnetic separation
US3826365A (en) * 1970-09-28 1974-07-30 Engelhard Min & Chem Beneficiating clay by selective flocculation and magnetic separation of impurities
US3983033A (en) * 1973-03-26 1976-09-28 Massachusetts Institute Of Technology Process for removing dissolved phosphorus from water magnetically
IT1176740B (it) * 1984-09-20 1987-08-18 Riserie Virginio Curti Spa Processo di trattamento del riso per migliorarne le caratteristiche qualitative alla cottura
US4664796A (en) 1985-09-16 1987-05-12 Coulter Electronics, Inc. Flux diverting flow chamber for high gradient magnetic separation of particles from a liquid medium
US4666595A (en) * 1985-09-16 1987-05-19 Coulter Electronics, Inc. Apparatus for acoustically removing particles from a magnetic separation matrix
US5512332A (en) * 1985-10-04 1996-04-30 Immunivest Corporation Process of making resuspendable coated magnetic particles
US5076950A (en) * 1985-12-20 1991-12-31 Syntex (U.S.A.) Inc. Magnetic composition for particle separation
IL87344A (en) * 1988-08-04 1992-03-29 Univ Bar Ilan Process for the production of gelatin from fish skins
DE68919715T2 (de) 1988-12-28 1995-04-06 Stefan Miltenyi Verfahren sowie materialien zur hochgraduierten magnetischen abspaltung biologischer materialien.
US5200084A (en) 1990-09-26 1993-04-06 Immunicon Corporation Apparatus and methods for magnetic separation
US5186827A (en) * 1991-03-25 1993-02-16 Immunicon Corporation Apparatus for magnetic separation featuring external magnetic means
US5466574A (en) * 1991-03-25 1995-11-14 Immunivest Corporation Apparatus and methods for magnetic separation featuring external magnetic means
US5391272A (en) * 1992-03-06 1995-02-21 Andcare, Inc. Electrochemical immunoassay methods
US5705059A (en) 1995-02-27 1998-01-06 Miltenyi; Stefan Magnetic separation apparatus
DE19516323C2 (de) * 1995-04-27 1997-02-27 Dirk Dipl Chem Guenther Verfahren zur Herstellung von magnetisierbaren Dispersionen und deren Verwendung
EP0928327A1 (en) * 1996-01-17 1999-07-14 Flinders Technologies Pty. Ltd. Solid phase enrichment of intact cells using intracellular constituents
JP3996644B2 (ja) * 1996-06-07 2007-10-24 イムニベスト・コーポレイション 外部及び内部勾配を有する磁気分離
US6451207B1 (en) 1997-06-04 2002-09-17 Dexter Magnetic Technologies, Inc. Magnetic cell separation device
US6241894B1 (en) 1997-10-10 2001-06-05 Systemix High gradient magnetic device and method for cell separation or purification
DE69934449T2 (de) * 1998-03-12 2007-09-27 Miltenyi Biotech Gmbh Mikrokolonnen-System für Magnettrennung
CN1128023C (zh) * 1999-05-31 2003-11-19 中国科学院化工冶金研究所 从流体中分离磁性颗粒的连续式高梯度磁分离方法及装置
US20030099954A1 (en) * 2001-11-26 2003-05-29 Stefan Miltenyi Apparatus and method for modification of magnetically immobilized biomolecules
US6984497B2 (en) * 2002-04-05 2006-01-10 Bio-Rad Laboratories, Inc. Reducing non-specific binding in immunoassays performed on polymeric solid phases
CA2431683C (en) 2003-06-20 2006-04-18 Irwin Elias Komery Migraine headache eye-rinse remedy solution
CA2532012C (en) 2003-08-26 2012-01-24 Unilever Plc Hair treatment compositions
WO2005062057A1 (de) 2003-12-01 2005-07-07 Dade Behring Marburg Gmbh Konjugate und deren verwendung in nachweisverfahren
CA2857741C (en) 2003-12-05 2017-06-13 Automed Technologies, Inc. Pharmacy dispensing system and method
DE102004003812A1 (de) 2004-01-25 2005-08-11 Aventis Pharma Deutschland Gmbh Arylsubstituierte Heterozyklen, Verfahren ihrer Herstellung und ihre Verwendung als Arzneimittel
DE102004005172A1 (de) 2004-02-02 2005-08-18 Aventis Pharma Deutschland Gmbh Indazolderivate als Inhibitoren der Hormon Sensitiven Lipase
AU2004318001A1 (en) 2004-03-04 2005-10-13 Composite Technology R & D Pty Limited Mixing drum
US7300631B2 (en) * 2005-05-02 2007-11-27 Bioscale, Inc. Method and apparatus for detection of analyte using a flexural plate wave device and magnetic particles
CN100546724C (zh) * 2006-06-30 2009-10-07 上海师范大学 磁性分离柱及其在生物样品分离中的应用

Also Published As

Publication number Publication date
ATE508800T1 (de) 2011-05-15
WO2009033947A2 (de) 2009-03-19
CN101977692A (zh) 2011-02-16
US20100273230A1 (en) 2010-10-28
DK2190585T3 (da) 2011-06-20
US10618056B2 (en) 2020-04-14
EP2190585A2 (de) 2010-06-02
JP2010539446A (ja) 2010-12-16
CN101977692B (zh) 2014-07-23
CA2698699A1 (en) 2009-03-19
DE102007043281A1 (de) 2009-05-28
CA2698699C (en) 2012-07-24
WO2009033947A3 (de) 2009-06-25
ES2366074T3 (es) 2011-10-17
US20160236204A1 (en) 2016-08-18
EP2190585B1 (de) 2011-05-11
JP4913244B2 (ja) 2012-04-11

Similar Documents

Publication Publication Date Title
HK1150995A1 (en) High gradient magnet separation of biological material
MX2008007716A (es) Metodo para eliminar extra corporalmente de la sangre un microbio patogeno, una celula inflamatoria o una proteina inflamatoria.
Wang et al. A novel experimental hypoxia chamber for cell culture
UA100901C2 (ru) Способ очищения фактора свертывания крови viii
EP3190180A3 (en) A method for identifying, expanding, and removing adult stem cells and cancer stem cells
MX2010000537A (es) Anticuerpos monoclonales contra glipicano-3.
MY163057A (en) Means and methods for trating dlblcl
UA116618C2 (uk) СКОНСТРУЙОВАНЕ НА ОСНОВІ ЦИСТЕЇНУ АНТИТІЛО ПРОТИ CD79b
ATE467405T1 (de) Implantierbare vorrichtung mit entfernbarem magneten
MX2009011341A (es) Metodo para hacer iman sinterizado de neodimio fierro boro.
NZ592928A (en) Method for treating parkinson' s disease using filamentous bacteriophage
NZ606970A (en) A method of treating attention deficit hyperactivity disorder
WO2007059382A3 (en) High purity magnetite formation process and apparatus, and product thereof
EP2046385A4 (en) COMPOSITION FOR MODULATING THE EXPRESSION OF CELL ADHESION MOLECULES
WO2009046457A3 (en) Imaging of genetic material with magnetic resonance
MD3625G2 (ro) Heptaazotat de hexa-(m-b-alanin-(O,O'))-m3-oxo-tri(aqua)trifier(III) 3,5-hidrat şi procedeu de obţinere a biomasei de Spirulina platensis
Li et al. Bacillus amyloliquefaciens PDR1 from root of karst adaptive plant enhances Arabidopsis thaliana resistance to alkaline stress through modulation of plasma membrane H+-ATPase activity
WO2007102812A3 (en) Natively glycosylated mammalian biological molecules produced by eletromagnetically stimulating living mammalian cells
WO2012085468A3 (fr) Methode pour mesurer la resistance de films
ZA200800010B (en) Device and method for the treatment of biomasses with permanent magnets
EA200801418A1 (ru) Повышение жизнеспособности и устойчивости к стрессу жизнеспособного биологического материала
SE0100728D0 (sv) New method
EA200601006A1 (ru) Биологическое удобрение, содержащее сыворотку
MX2008000232A (es) Moleculas biologicas de mamifero naturalmente glucosiladas, producidas al estimular electromagneticamente celulas de mamifero vivas.
UA84761C2 (ru) Способ повышения усвоения растительных белков

Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20180824