HK1147750A1 - Amino arylsulfonamide compounds and their use as 5-ht6 ligands - Google Patents

Amino arylsulfonamide compounds and their use as 5-ht6 ligands

Info

Publication number
HK1147750A1
HK1147750A1 HK11101861.1A HK11101861A HK1147750A1 HK 1147750 A1 HK1147750 A1 HK 1147750A1 HK 11101861 A HK11101861 A HK 11101861A HK 1147750 A1 HK1147750 A1 HK 1147750A1
Authority
HK
Hong Kong
Prior art keywords
compounds
pharmaceutically acceptable
disorders
ligands
stereoisomers
Prior art date
Application number
HK11101861.1A
Other languages
English (en)
Inventor
Nirogi Venkata Satya Ramakrishna
Rama Sastri Kambhampati
Anil Karbhari Shinde
Nagaraj Vishwottam Kandikere
Venkateswarlu Jasti
Original Assignee
Suven Life Sciences Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Suven Life Sciences Ltd filed Critical Suven Life Sciences Ltd
Publication of HK1147750A1 publication Critical patent/HK1147750A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Hospice & Palliative Care (AREA)
  • Obesity (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Indole Compounds (AREA)
HK11101861.1A 2007-10-26 2011-02-25 Amino arylsulfonamide compounds and their use as 5-ht6 ligands HK1147750A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN2433CH2007 2007-10-26
PCT/IN2008/000281 WO2009053997A1 (en) 2007-10-26 2008-05-02 Amino arylsulfonamide compounds and their use as 5-ht6 ligands

Publications (1)

Publication Number Publication Date
HK1147750A1 true HK1147750A1 (en) 2011-08-19

Family

ID=39769531

Family Applications (1)

Application Number Title Priority Date Filing Date
HK11101861.1A HK1147750A1 (en) 2007-10-26 2011-02-25 Amino arylsulfonamide compounds and their use as 5-ht6 ligands

Country Status (21)

Country Link
US (1) US7964627B2 (sl)
EP (1) EP2200980B9 (sl)
JP (1) JP5236001B2 (sl)
KR (1) KR101268654B1 (sl)
CN (1) CN101835748B (sl)
AT (1) ATE518833T1 (sl)
AU (1) AU2008315309B2 (sl)
BR (1) BRPI0816571A2 (sl)
CA (1) CA2703157C (sl)
CY (1) CY1112181T1 (sl)
DK (1) DK2200980T3 (sl)
EA (1) EA017154B1 (sl)
ES (1) ES2370680T3 (sl)
HK (1) HK1147750A1 (sl)
HR (1) HRP20110780T2 (sl)
IL (1) IL205231A (sl)
MX (1) MX2010003765A (sl)
NZ (1) NZ585374A (sl)
SI (1) SI2200980T1 (sl)
WO (1) WO2009053997A1 (sl)
ZA (1) ZA201002165B (sl)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102153884B (zh) * 2011-02-16 2013-06-19 连云港清泰化工有限公司 一种墨水型染料及其制备方法与用途
EP2763676B1 (en) 2011-10-03 2019-12-25 The University of Utah Research Foundation Application of 5-ht6 receptor antagonists for the alleviation of cognitive deficits of down syndrome
CA2862363C (en) * 2012-02-02 2021-06-08 Joan M. Fallon Enzyme compositions and use thereof for wound healing
CN104725295B (zh) 2013-12-20 2019-05-24 广东东阳光药业有限公司 芳杂环类衍生物及其在药物上的应用
NZ728907A (en) * 2014-08-16 2017-12-22 Suven Life Sciences Ltd Active metabolite of 1-[(2-bromophenyl) sulfonyl]-5-methoxy-3- [(4-methyl-1-piperazinyl) methyl]-1h-indole dimesylate monohydrate and dimesylate dihydrate salt of active metabolite

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DZ2376A1 (fr) 1996-12-19 2002-12-28 Smithkline Beecham Plc Dérivés de sulfonamides nouveaux procédé pour leurpréparation et compositions pharmaceutiques les c ontenant.
HUP0003073A3 (en) 1997-07-11 2002-10-28 Smithkline Beecham Plc Benzenesulfonamide derivatives, process for producing them and their use as medicines
SI0930302T1 (sl) * 1998-01-16 2003-10-31 F. Hoffmann-La Roche Ag Benzosulfonski derivati
GB9801392D0 (en) 1998-01-22 1998-03-18 Smithkline Beecham Plc Novel compounds
GB9803411D0 (en) 1998-02-18 1998-04-15 Smithkline Beecham Plc Novel compounds
DE69937372T2 (de) 1999-04-21 2008-06-26 Nps Allelix Corp., Mississauga Piperidin-indol derivate mit 5-ht6 affinität
GB9926302D0 (en) 1999-11-05 2000-01-12 Smithkline Beecham Plc Novel compounds
DE60214990T2 (de) 2001-01-30 2007-04-05 Eli Lilly And Co., Indianapolis Benzolsulfonsäureester-indol-5-yl als 5-ht6 rezeptor-antagonisten
WO2002098878A1 (en) 2001-02-08 2002-12-12 Memory Pharmaceuticals Corporation Trifluoromethylpurines as phosphodiesterase 4 inhibitors
SK16052003A3 (en) 2001-06-07 2004-10-05 Hoffmann La Roche New indole derivatives with 5-HT6 receptor affinity
JP2005528587A (ja) 2002-02-01 2005-09-22 バイエル・ヘルスケア・アクチェンゲゼルシャフト 新規ヒト５−ｈｔ６受容体に関連する疾患のための診断用および治療用物質
EP1471912A1 (en) 2002-02-05 2004-11-03 Glaxo Group Limited Method of promoting neuronal growth
WO2003080580A2 (en) 2002-03-27 2003-10-02 Glaxo Group Limited Quinoline derivatives and their use as 5-ht6 ligands
ES2274285T3 (es) * 2002-10-18 2007-05-16 F. Hoffmann-La Roche Ag 4-piperanzinilbencenosulfonilindoles con afinidad al receptor 5-ht6.
ES2310243T3 (es) 2002-11-28 2009-01-01 Suven Life Sciences Limited Indoles n-aril-3-sulfonil sustituidos que tienen afinidad por receptores de serotonina, proceso para su preparacion y composicion farmaceutica que los contiene.
KR100776118B1 (ko) 2002-11-28 2007-11-15 수벤 라이프 사이언시스 리미티드 엔-아릴술포닐-3-아미노알콕시인돌
WO2004048331A1 (en) * 2002-11-28 2004-06-10 Suven Life Sciences Limited N-arylalkyl-3-aminoalkoxyindoles and their use as 5-ht ligands
JP4571507B2 (ja) * 2002-12-18 2010-10-27 スベン ライフ サイエンシズ リミティド セロトニン受容体親和性を有する四環系３−置換インドール
CN101258144B (zh) * 2005-08-12 2012-05-30 苏文生命科学有限公司 作为功能性5-ht6配体的氨基芳基磺酰胺衍生物

Also Published As

Publication number Publication date
BRPI0816571A2 (pt) 2015-12-22
IL205231A0 (en) 2010-12-30
EP2200980A1 (en) 2010-06-30
US20100216861A1 (en) 2010-08-26
CN101835748A (zh) 2010-09-15
AU2008315309B2 (en) 2011-06-09
ZA201002165B (en) 2011-05-25
SI2200980T1 (sl) 2011-12-30
MX2010003765A (es) 2010-04-30
CA2703157C (en) 2013-02-05
JP2011500792A (ja) 2011-01-06
CA2703157A1 (en) 2009-04-30
CY1112181T1 (el) 2015-12-09
US7964627B2 (en) 2011-06-21
JP5236001B2 (ja) 2013-07-17
WO2009053997A1 (en) 2009-04-30
ATE518833T1 (de) 2011-08-15
KR20100069707A (ko) 2010-06-24
KR101268654B1 (ko) 2013-05-29
CN101835748B (zh) 2012-11-14
HRP20110780T2 (hr) 2018-06-29
ES2370680T9 (es) 2012-02-15
HRP20110780T1 (en) 2011-11-30
IL205231A (en) 2014-03-31
EP2200980B1 (en) 2011-08-03
AU2008315309A1 (en) 2009-04-30
ES2370680T3 (es) 2011-12-21
EA017154B1 (ru) 2012-10-30
DK2200980T3 (da) 2011-11-21
EA201070527A1 (ru) 2010-10-29
EP2200980B9 (en) 2011-12-28
NZ585374A (en) 2011-09-30

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20210429