HK1132744A1 - Bruton's tyrosine kinase activity probe and method of using bruton's - Google Patents

Bruton's tyrosine kinase activity probe and method of using bruton's

Info

Publication number
HK1132744A1
HK1132744A1 HK10100318.3A HK10100318A HK1132744A1 HK 1132744 A1 HK1132744 A1 HK 1132744A1 HK 10100318 A HK10100318 A HK 10100318A HK 1132744 A1 HK1132744 A1 HK 1132744A1
Authority
HK
Hong Kong
Prior art keywords
bruton
tyrosine kinase
kinase activity
activity probe
probe
Prior art date
Application number
HK10100318.3A
Other languages
English (en)
Inventor
Zhengying Pan
Shyr Jiann Li
Heleen Schereens
Lee Honigberg
Erik Verner
Original Assignee
Pharmacyclics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacyclics Inc filed Critical Pharmacyclics Inc
Publication of HK1132744A1 publication Critical patent/HK1132744A1/xx

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/91—Transferases (2.)
    • G01N2333/912—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • G01N2333/91205—Phosphotransferases in general
    • G01N2333/9121—Phosphotransferases in general with an alcohol group as acceptor (2.7.1), e.g. general tyrosine, serine or threonine kinases
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Food Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
HK10100318.3A 2006-11-03 2010-01-12 Bruton's tyrosine kinase activity probe and method of using bruton's HK1132744A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US86435006P 2006-11-03 2006-11-03
PCT/US2007/023306 WO2008054827A2 (en) 2006-11-03 2007-11-05 Bruton's tyrosine kinase activity probe and method of using

Publications (1)

Publication Number Publication Date
HK1132744A1 true HK1132744A1 (en) 2010-03-05

Family

ID=39344933

Family Applications (1)

Application Number Title Priority Date Filing Date
HK10100318.3A HK1132744A1 (en) 2006-11-03 2010-01-12 Bruton's tyrosine kinase activity probe and method of using bruton's

Country Status (6)

Country Link
US (2) US8987233B2 (es)
EP (1) EP2089391B1 (es)
CA (1) CA2668286C (es)
ES (1) ES2403546T3 (es)
HK (1) HK1132744A1 (es)
WO (1) WO2008054827A2 (es)

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