HK1129298A1 - Dihydrodiazepines useful as inhibitors of protein kinases - Google Patents
Dihydrodiazepines useful as inhibitors of protein kinasesInfo
- Publication number
- HK1129298A1 HK1129298A1 HK09106822.2A HK09106822A HK1129298A1 HK 1129298 A1 HK1129298 A1 HK 1129298A1 HK 09106822 A HK09106822 A HK 09106822A HK 1129298 A1 HK1129298 A1 HK 1129298A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- dihydrodiazepines
- inhibitors
- useful
- protein kinases
- kinases
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
- C07D487/14—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pulmonology (AREA)
- Oncology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Hematology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Transplantation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US77299206P | 2006-02-14 | 2006-02-14 | |
US83137106P | 2006-07-17 | 2006-07-17 | |
US84935306P | 2006-10-04 | 2006-10-04 | |
US87620606P | 2006-12-21 | 2006-12-21 | |
PCT/US2007/003699 WO2007095188A2 (en) | 2006-02-14 | 2007-02-13 | Dihydrodiazepines useful as inhibitors of protein kinases |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1129298A1 true HK1129298A1 (en) | 2009-11-27 |
Family
ID=38330249
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK09106822.2A HK1129298A1 (en) | 2006-02-14 | 2009-07-24 | Dihydrodiazepines useful as inhibitors of protein kinases |
Country Status (16)
Country | Link |
---|---|
US (4) | US7622463B2 (de) |
EP (1) | EP1983987B1 (de) |
JP (2) | JP5243970B2 (de) |
KR (1) | KR20080095902A (de) |
AR (1) | AR059505A1 (de) |
AT (1) | ATE479434T1 (de) |
AU (1) | AU2007215221C1 (de) |
CA (1) | CA2652648C (de) |
DE (1) | DE602007008837D1 (de) |
HK (1) | HK1129298A1 (de) |
IL (1) | IL193240A0 (de) |
NO (1) | NO20083918L (de) |
NZ (1) | NZ570530A (de) |
RU (1) | RU2475488C2 (de) |
TW (1) | TW200804389A (de) |
WO (1) | WO2007095188A2 (de) |
Families Citing this family (52)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TW200808325A (en) * | 2006-07-06 | 2008-02-16 | Astrazeneca Ab | Novel compounds |
AU2008228303B2 (en) * | 2007-03-22 | 2012-04-19 | Takeda Pharmaceutical Company Limited | Substituted pyrimidodiazepines useful as PLK1 inhibitors |
TW200914457A (en) * | 2007-05-31 | 2009-04-01 | Kyowa Hakko Kogyo Kk | Pyrimidodiazepinone derivative |
PT2168966T (pt) | 2007-06-15 | 2017-01-02 | Msd Kk | Derivado de bicicloanilina |
NZ583061A (en) | 2007-08-15 | 2012-06-29 | Vertex Pharma | 4-(9-(3,3-difluorocyclopentyl)-5,7,7-trimethyl-6-oxo-6,7,8,9-tetrahydro-5h-pyrimido[4,5-b[1,4]diazepin-2-ylamino)-3-methoxybenzamide derivatives as inhibitors of the human protein kinases plk1 to plk4 for the treatment of proliferative diseases |
MY152283A (en) | 2007-09-25 | 2014-09-15 | Takeda Pharmaceutical | Polo-like kinase inhibitirs |
WO2009040556A1 (en) | 2007-09-28 | 2009-04-02 | Cyclacel Limited | Pyrimidine derivatives as protein kinase inhibitors |
WO2009067547A1 (en) * | 2007-11-19 | 2009-05-28 | Takeda Pharmaceutical Company Limited | Polo-like kinase inhibitors |
WO2009071480A2 (en) * | 2007-12-04 | 2009-06-11 | Nerviano Medical Sciences S.R.L. | Substituted dihydropteridin-6-one derivatives, process for their preparation and their use as kinase inhibitors |
JP2011527667A (ja) | 2008-06-18 | 2011-11-04 | 武田薬品工業株式会社 | ハロ置換ピリミドジアゼピン |
MX2011000021A (es) * | 2008-06-23 | 2011-02-24 | Vertex Pharma | Inhibidores de proteina cinasas. |
KR20110039278A (ko) * | 2008-06-23 | 2011-04-15 | 버텍스 파마슈티칼스 인코포레이티드 | 단백질 키나제 억제제 |
UY32306A (es) | 2008-12-09 | 2010-07-30 | Gilead Sciences Inc | Derivados de pteridinona y pirimidinodiazepinona y composiciones farmacéuticas que modulan en forma selectiva los receptores tipo toll, métodos y usos |
EP2379559B1 (de) * | 2009-01-06 | 2017-10-25 | Dana-Farber Cancer Institute, Inc. | Pyrimido-diazepinon-kinasegerüstverbindungen und verfahren zur behandlung von erkrankungen |
EP2414358A1 (de) * | 2009-03-31 | 2012-02-08 | ArQule, Inc. | Substituierte tetrahydropyrazolopyridoazepinverbindungen |
NZ619259A (en) | 2009-06-17 | 2015-07-31 | Vertex Pharma | Inhibitors of influenza viruses replication |
WO2011038185A2 (en) * | 2009-09-25 | 2011-03-31 | Vertex Pharmaceuticals Incorporated | Methods for preparing pyrimidine derivatives useful as protein kinase inhibitors |
MX2012003484A (es) * | 2009-09-25 | 2012-04-20 | Vertex Pharma | Metodos para preparar derivados de pirimidina utiles como inhibidores de proteina cinasa. |
WO2011123678A2 (en) | 2010-03-31 | 2011-10-06 | Arqule, Inc. | Substituted benzo-pyrido-triazolo-diazepine compounds |
BR112012029057A2 (pt) | 2010-05-14 | 2020-10-13 | Dana-Farber Cancer Institute, Inc. | composições e métodos de tratamento de leucemia |
BR122014024883A2 (pt) | 2010-05-14 | 2019-08-20 | Dana-Farber Cancer Institute, Inc. | Compostos no tratamento de neoplasia |
WO2011143657A1 (en) | 2010-05-14 | 2011-11-17 | Dana-Farber Cancer Institute, Inc. | Male contraceptive compositions and methods of use |
US8933070B2 (en) | 2010-07-02 | 2015-01-13 | University Health Network | Methods of targeting PTEN mutant diseases and compositions therefor |
CN103492381A (zh) | 2010-12-16 | 2014-01-01 | 沃泰克斯药物股份有限公司 | 流感病毒复制的抑制剂 |
UA118010C2 (uk) | 2011-08-01 | 2018-11-12 | Вертекс Фармасьютікалз Інкорпорейтед | Інгібітори реплікації вірусів грипу |
WO2014159392A1 (en) | 2013-03-14 | 2014-10-02 | Dana-Farber Cancer Institute, Inc. | Bromodomain binding reagents and uses thereof |
EP3670515B1 (de) | 2013-03-15 | 2024-03-06 | Dana-Farber Cancer Institute, Inc. | Pyrimidodiazepinonverbindungen und verfahren zur behandlung von erkrankungen |
US9975896B2 (en) | 2013-07-25 | 2018-05-22 | Dana-Farber Cancer Institute, Inc. | Inhibitors of transcription factors and uses thereof |
CN105849110B (zh) | 2013-11-08 | 2019-08-02 | 达纳-法伯癌症研究所有限公司 | 使用溴结构域和额外终端(bet)蛋白抑制剂的用于癌症的组合疗法 |
CA2930297C (en) | 2013-11-13 | 2022-04-05 | Vertex Pharmaceuticals Incorporated | Methods of preparing inhibitors of influenza viruses replication |
CN105849100B (zh) | 2013-11-13 | 2019-07-16 | 沃泰克斯药物股份有限公司 | 流感病毒复制抑制剂 |
EP3099696A4 (de) * | 2014-01-31 | 2017-07-05 | Dana-Farber Cancer Institute, Inc. | Diazepanderivate und verwendungen davon |
JP2017504651A (ja) * | 2014-01-31 | 2017-02-09 | ダナ−ファーバー キャンサー インスティテュート, インコーポレイテッド | ジアゼパン誘導体の使用 |
WO2015117053A1 (en) | 2014-01-31 | 2015-08-06 | Dana-Farber Cancer Institute, Inc. | Diaminopyrimidine benzenesulfone derivatives and uses thereof |
RU2722179C2 (ru) | 2014-02-28 | 2020-05-28 | Тэнша Терапеутикс, Инк. | Лечение состояний, ассоциированных с гиперинсулинемией |
GB201411581D0 (en) * | 2014-06-30 | 2014-08-13 | Inst Europ Di Oncologia S R L | Compounds inhibiting the enzyme monopolar spindle 1 kinase, pharmaceutical compositions and uses thereof |
TWI806081B (zh) | 2014-07-11 | 2023-06-21 | 美商基利科學股份有限公司 | 用於治療HIV之toll樣受體調節劑 |
WO2016022902A1 (en) | 2014-08-08 | 2016-02-11 | Dana-Farber Cancer Institute, Inc. | Diazepane derivatives and uses thereof |
CN106793775B (zh) | 2014-08-08 | 2020-06-02 | 达纳-法伯癌症研究所股份有限公司 | 二氢碟啶酮衍生物及其用途 |
PT3194401T (pt) | 2014-09-16 | 2020-12-23 | Gilead Sciences Inc | Formas sólidas de modulador de recetor tipo toll |
EP3212654B1 (de) | 2014-10-27 | 2020-04-08 | Tensha Therapeutics, Inc. | Bromdomänenhemmer |
CN107428747A (zh) | 2014-11-25 | 2017-12-01 | 拜耳制药股份公司 | 取代的吡啶并苯并二氮杂*酮衍生物及其用途 |
JP6857617B2 (ja) | 2015-05-13 | 2021-04-14 | バーテックス ファーマシューティカルズ インコーポレイテッドVertex Pharmaceuticals Incorporated | インフルエンザウイルスの複製の阻害剤 |
JP6704416B2 (ja) | 2015-05-13 | 2020-06-03 | バーテックス ファーマシューティカルズ インコーポレイテッドVertex Pharmaceuticals Incorporated | インフルエンザウイルスの複製の阻害剤を調製する方法 |
WO2016201370A1 (en) | 2015-06-12 | 2016-12-15 | Dana-Farber Cancer Institute, Inc. | Combination therapy of transcription inhibitors and kinase inhibitors |
US10881668B2 (en) | 2015-09-11 | 2021-01-05 | Dana-Farber Cancer Institute, Inc. | Acetamide thienotriazolodiazepines and uses thereof |
CA2996974A1 (en) | 2015-09-11 | 2017-03-16 | Dana-Farber Cancer Institute, Inc. | Cyano thienotriazolodiazepines and uses thereof |
AU2016361478B2 (en) | 2015-11-25 | 2020-09-10 | Dana-Farber Cancer Institute, Inc. | Bivalent bromodomain inhibitors and uses thereof |
TWI794742B (zh) | 2020-02-18 | 2023-03-01 | 美商基利科學股份有限公司 | 抗病毒化合物 |
KR20220125156A (ko) | 2021-03-04 | 2022-09-14 | 한양대학교 에리카산학협력단 | 피리디닐 피라졸 유도체 또는 이의 약학적으로 허용가능한 염 및 이의 용도 |
US11697666B2 (en) | 2021-04-16 | 2023-07-11 | Gilead Sciences, Inc. | Methods of preparing carbanucleosides using amides |
KR20230076333A (ko) | 2021-11-24 | 2023-05-31 | 한양대학교 에리카산학협력단 | 이속사졸 유도체 또는 이의 약학적으로 허용가능한 염 및 이의 용도 |
Family Cites Families (19)
Publication number | Priority date | Publication date | Assignee | Title |
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JPS5638032B2 (de) | 1972-08-31 | 1981-09-03 | ||
US3880855A (en) * | 1973-04-16 | 1975-04-29 | Bristol Myers Co | 5,6-DIHYDRO-11-H-pyrimido{8 4,5-b{9 {8 1,4{9 benzodiazepines |
US3872122A (en) * | 1973-04-16 | 1975-03-18 | Bristol Myers Co | 11 H-Pyrimido{8 4,5-b{9 {8 1,4{9 benzodiazepines |
JPS51110202A (en) | 1975-03-24 | 1976-09-29 | Susumu Nojima | Denwakyono hyojisochi |
GB8927872D0 (en) | 1989-12-08 | 1990-02-14 | Beecham Group Plc | Pharmaceuticals |
US6011029A (en) * | 1996-02-26 | 2000-01-04 | Bristol-Myers Squibb Company | Inhibitors of farnesyl protein transferase |
JP2003509425A (ja) | 1999-09-15 | 2003-03-11 | ワーナー−ランバート・カンパニー | キナーゼ阻害剤としてのプテリジノン |
TR200201506T2 (tr) * | 1999-09-17 | 2002-10-21 | Abbott Gmbh & Co. Kg | Terapötik maddeler olarak kinaz inhibitörleri |
US7101869B2 (en) * | 1999-11-30 | 2006-09-05 | Pfizer Inc. | 2,4-diaminopyrimidine compounds useful as immunosuppressants |
EE200200275A (et) | 1999-11-30 | 2003-10-15 | Pfizer Products Inc. | Immunosupressantidena kasutatavad 2,4-diaminopürimidiiniühendid |
EP1427730B1 (de) | 2001-09-04 | 2006-07-12 | Boehringer Ingelheim Pharma GmbH & Co.KG | Neue dihydropteridinone, verfahren zu deren herstellung und deren verwendung als arzneimittel |
CN100537570C (zh) | 2003-02-26 | 2009-09-09 | 贝林格尔英格海姆法玛两合公司 | 二氢蝶啶酮、其制法及作为药物制剂的用途 |
US6861422B2 (en) * | 2003-02-26 | 2005-03-01 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Dihydropteridinones, processes for preparing them and their use as pharmaceutical compositions |
DE102004029784A1 (de) | 2004-06-21 | 2006-01-05 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue 2-Benzylaminodihydropteridinone, Verfahren zur deren Herstellung und deren Verwendung als Arzneimittel |
DE102004058337A1 (de) | 2004-12-02 | 2006-06-14 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Verfahren zur Herstellung von annelierten Piperazin-2-on Derivaten |
MY152283A (en) | 2007-09-25 | 2014-09-15 | Takeda Pharmaceutical | Polo-like kinase inhibitirs |
JP4941835B2 (ja) | 2007-09-28 | 2012-05-30 | Toto株式会社 | キャビネット及びキャビネットの施工方法 |
WO2009040556A1 (en) | 2007-09-28 | 2009-04-02 | Cyclacel Limited | Pyrimidine derivatives as protein kinase inhibitors |
JP5035192B2 (ja) | 2008-09-19 | 2012-09-26 | コニカミノルタアドバンストレイヤー株式会社 | 駆動機構、駆動装置 |
-
2007
- 2007-02-13 JP JP2008555299A patent/JP5243970B2/ja active Active
- 2007-02-13 DE DE602007008837T patent/DE602007008837D1/de active Active
- 2007-02-13 NZ NZ570530A patent/NZ570530A/en unknown
- 2007-02-13 CA CA2652648A patent/CA2652648C/en active Active
- 2007-02-13 WO PCT/US2007/003699 patent/WO2007095188A2/en active Application Filing
- 2007-02-13 KR KR1020087022521A patent/KR20080095902A/ko active IP Right Grant
- 2007-02-13 RU RU2008136854/04A patent/RU2475488C2/ru not_active IP Right Cessation
- 2007-02-13 US US11/706,070 patent/US7622463B2/en active Active
- 2007-02-13 AT AT07750530T patent/ATE479434T1/de active
- 2007-02-13 AU AU2007215221A patent/AU2007215221C1/en active Active
- 2007-02-13 TW TW096105339A patent/TW200804389A/zh unknown
- 2007-02-13 EP EP07750530A patent/EP1983987B1/de active Active
- 2007-02-14 AR ARP070100633A patent/AR059505A1/es unknown
-
2008
- 2008-08-05 IL IL193240A patent/IL193240A0/en unknown
- 2008-09-15 NO NO20083918A patent/NO20083918L/no not_active Application Discontinuation
-
2009
- 2009-07-24 HK HK09106822.2A patent/HK1129298A1/xx not_active IP Right Cessation
- 2009-09-29 US US12/569,237 patent/US8022202B2/en active Active
-
2011
- 2011-08-10 US US13/206,638 patent/US8394952B2/en active Active
-
2013
- 2013-01-21 US US13/745,968 patent/US20140038935A1/en not_active Abandoned
- 2013-01-23 JP JP2013009857A patent/JP2013067666A/ja not_active Withdrawn
Also Published As
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US20100190765A1 (en) | 2010-07-29 |
TW200804389A (en) | 2008-01-16 |
RU2008136854A (ru) | 2010-03-20 |
WO2007095188A3 (en) | 2007-10-25 |
IL193240A0 (en) | 2009-08-03 |
RU2475488C2 (ru) | 2013-02-20 |
US20120149898A1 (en) | 2012-06-14 |
US20140038935A1 (en) | 2014-02-06 |
AU2007215221B2 (en) | 2013-01-17 |
US8022202B2 (en) | 2011-09-20 |
ATE479434T1 (de) | 2010-09-15 |
US20080167289A1 (en) | 2008-07-10 |
DE602007008837D1 (de) | 2010-10-14 |
EP1983987B1 (de) | 2010-09-01 |
JP2013067666A (ja) | 2013-04-18 |
EP1983987A2 (de) | 2008-10-29 |
US8394952B2 (en) | 2013-03-12 |
NZ570530A (en) | 2011-09-30 |
AU2007215221C1 (en) | 2013-05-30 |
NO20083918L (no) | 2008-11-12 |
KR20080095902A (ko) | 2008-10-29 |
WO2007095188A2 (en) | 2007-08-23 |
AR059505A1 (es) | 2008-04-09 |
CA2652648A1 (en) | 2007-08-23 |
US7622463B2 (en) | 2009-11-24 |
AU2007215221A1 (en) | 2007-08-23 |
CA2652648C (en) | 2016-10-25 |
JP2009526849A (ja) | 2009-07-23 |
JP5243970B2 (ja) | 2013-07-24 |
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Effective date: 20180213 |