HK1126412A1 - Crystalline pyrimidine nucleoside derivatives suspensions in capsules - Google Patents

Crystalline pyrimidine nucleoside derivatives suspensions in capsules

Info

Publication number
HK1126412A1
HK1126412A1 HK09105247.1A HK09105247A HK1126412A1 HK 1126412 A1 HK1126412 A1 HK 1126412A1 HK 09105247 A HK09105247 A HK 09105247A HK 1126412 A1 HK1126412 A1 HK 1126412A1
Authority
HK
Hong Kong
Prior art keywords
capsules
suspensions
pyrimidine nucleoside
nucleoside derivatives
crystalline pyrimidine
Prior art date
Application number
HK09105247.1A
Other languages
English (en)
Inventor
Robert Westwood
Alistair Selkirk
Original Assignee
Cyclacel Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cyclacel Ltd filed Critical Cyclacel Ltd
Publication of HK1126412A1 publication Critical patent/HK1126412A1/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4808Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/513Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4866Organic macromolecular compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
HK09105247.1A 2005-12-23 2009-06-11 Crystalline pyrimidine nucleoside derivatives suspensions in capsules HK1126412A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0526419.7A GB0526419D0 (en) 2005-12-23 2005-12-23 Formulation
PCT/GB2006/004927 WO2007072061A2 (en) 2005-12-23 2006-12-22 Crystalline pyrimidine nucleoside derivatives suspensions in capsules

Publications (1)

Publication Number Publication Date
HK1126412A1 true HK1126412A1 (en) 2009-09-04

Family

ID=35841215

Family Applications (1)

Application Number Title Priority Date Filing Date
HK09105247.1A HK1126412A1 (en) 2005-12-23 2009-06-11 Crystalline pyrimidine nucleoside derivatives suspensions in capsules

Country Status (17)

Country Link
US (1) US8497291B2 (xx)
EP (1) EP1962814B1 (xx)
JP (2) JP5443763B2 (xx)
CN (1) CN101346132B (xx)
AU (1) AU2006327951B2 (xx)
BR (1) BRPI0620229B8 (xx)
CA (1) CA2633308C (xx)
DK (1) DK1962814T3 (xx)
ES (1) ES2672106T3 (xx)
GB (1) GB0526419D0 (xx)
HK (1) HK1126412A1 (xx)
HU (1) HUE039368T2 (xx)
IL (1) IL192348A (xx)
PT (1) PT1962814T (xx)
RU (1) RU2428972C2 (xx)
TR (1) TR201808182T4 (xx)
WO (1) WO2007072061A2 (xx)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2039700A2 (en) 2001-04-30 2009-03-25 Glaxo Group Limited Novel anti-inflammatory androstane derivatives
GB0625283D0 (en) 2006-12-19 2007-01-24 Cyclacel Ltd Combination
JP5852309B2 (ja) * 2007-04-25 2016-02-03 サイクラセル リミテッド 増殖性疾患を治療するためのサパシタビンの使用
US8124593B2 (en) 2007-11-05 2012-02-28 Cyclacel Limited Methods of treatment using sapacitabine
GB0808357D0 (en) 2008-05-08 2008-06-18 Cyclacel Ltd Process
CA2725295C (en) 2008-06-09 2016-11-08 Cyclacel Limited Combination of sapacitabine (cndac) and dna methyltransferase inhibitors such as decitabine and procaine
WO2010131475A1 (ja) * 2009-05-15 2010-11-18 大鵬薬品工業株式会社 1-(2'-シアノ-2'-デオキシ-β-D-アラビノフラノシル)シトシン・一塩酸塩の新規安定形結晶
PL2575784T3 (pl) 2010-06-02 2019-03-29 Astellas Deutschland Gmbh Doustne postaci dawkowania bendamustyny
WO2012140436A1 (en) 2011-04-14 2012-10-18 Cyclacel Limited Dosage regimen for sapacitabine and decitabine in combination for treating acute myeloid leukemia
JP5873375B2 (ja) * 2012-04-03 2016-03-01 中日本カプセル 株式会社 ソフトカプセル及びソフトカプセルの製造方法
JP6286421B2 (ja) 2012-05-15 2018-02-28 サイクラセル リミテッド サパシタビン及びセリシクリブの投与レジメン
JP6537980B2 (ja) 2013-02-28 2019-07-03 プロノヴァ・バイオファーマ・ノルゲ・アーエスPronova BioPharma Norge AS 脂質化合物、トリグリセリドおよび界面活性剤を含む組成物、ならびにその使用方法
CN106963742B (zh) * 2016-11-07 2021-02-23 澳门大学 中药固液胶囊及其制备方法
WO2019081951A1 (en) 2017-10-27 2019-05-02 Cyclacel Limited DOSAGE REGIME
WO2021079129A1 (en) 2019-10-24 2021-04-29 Cyclacel Limited Dosing regimen

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE174917T1 (de) * 1991-04-22 1999-01-15 Otsuka Pharma Co Ltd Pyrazolo(1,5-a>pyrimidinderivate und sie enthaltende antiinflammatorische mittel
CA2079413C (en) * 1991-09-30 2003-09-09 Masakatsu Kaneko Pyrimidine nucleoside derivatives having anti-tumor activity, their preparation and use
DE4322826A1 (de) * 1993-07-08 1995-01-12 Galenik Labor Freiburg Gmbh Pharmazeutisches Präparat
US5599922A (en) * 1994-03-18 1997-02-04 Lynx Therapeutics, Inc. Oligonucleotide N3'-P5' phosphoramidates: hybridization and nuclease resistance properties
KR19980073479A (ko) * 1997-03-14 1998-11-05 한스루돌프하우스, 니콜케르커 사이클로스포린-함유 연질캅셀제
NL1003503C2 (nl) * 1996-07-04 1998-01-07 Negma Steba International Dev Farmaceutische samenstelling voor orale toediening.
GB9918885D0 (en) * 1999-08-10 1999-10-13 Pharmacia & Upjohn Spa Pharmaceutical formulations in hydroxypropymethycellulose capsules
US6908906B2 (en) * 2001-02-09 2005-06-21 Sankyo Company, Limited Crystalline forms of pyrimidine nucleoside derivative
JP3748536B2 (ja) * 2001-02-09 2006-02-22 三共株式会社 ピリミジンヌクレオシド誘導体の結晶
JP2005531495A (ja) * 2001-12-21 2005-10-20 シャイア ラボラトリーズ,インコーポレイテッド 高い物理的安定性を有する経口カプセル製剤
JP5096658B2 (ja) * 2003-10-06 2012-12-12 株式会社三協 生物学的利用能を向上させたソフトカプセル
US20050249802A1 (en) * 2004-05-06 2005-11-10 The Procter & Gamble Company Softgel encapsulated pharmaceutical compositions comprising concentrated active ingredients
GB0413730D0 (en) 2004-06-18 2004-07-21 Tillotts Pharma Ag A pharmaceutical composition and its use

Also Published As

Publication number Publication date
AU2006327951A1 (en) 2007-06-28
EP1962814B1 (en) 2018-04-25
RU2008130411A (ru) 2010-01-27
EP1962814A2 (en) 2008-09-03
GB0526419D0 (en) 2006-02-08
DK1962814T3 (en) 2018-08-06
BRPI0620229B8 (pt) 2021-05-25
AU2006327951B2 (en) 2012-09-06
US8497291B2 (en) 2013-07-30
BRPI0620229A2 (pt) 2011-11-01
IL192348A (en) 2016-02-29
BRPI0620229A8 (pt) 2018-01-02
WO2007072061A3 (en) 2007-10-25
WO2007072061A2 (en) 2007-06-28
CA2633308C (en) 2014-06-17
ES2672106T3 (es) 2018-06-12
TR201808182T4 (tr) 2018-07-23
CN101346132A (zh) 2009-01-14
CA2633308A1 (en) 2007-06-28
PT1962814T (pt) 2018-06-22
JP5443763B2 (ja) 2014-03-19
RU2428972C2 (ru) 2011-09-20
CN101346132B (zh) 2013-01-16
HUE039368T2 (hu) 2018-12-28
IL192348A0 (en) 2009-08-03
JP2013189463A (ja) 2013-09-26
BRPI0620229B1 (pt) 2020-09-15
US20090074856A1 (en) 2009-03-19
JP2009520797A (ja) 2009-05-28

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20221227