HK1124639A1 - Debriding composition from bromelain and methods of production thereof - Google Patents

Debriding composition from bromelain and methods of production thereof

Info

Publication number
HK1124639A1
HK1124639A1 HK09103888.0A HK09103888A HK1124639A1 HK 1124639 A1 HK1124639 A1 HK 1124639A1 HK 09103888 A HK09103888 A HK 09103888A HK 1124639 A1 HK1124639 A1 HK 1124639A1
Authority
HK
Hong Kong
Prior art keywords
bromelain
production
methods
debriding composition
debriding
Prior art date
Application number
HK09103888.0A
Other languages
English (en)
Inventor
Marian Gorecki
Amir Toren
Original Assignee
Mediwound Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mediwound Ltd filed Critical Mediwound Ltd
Publication of HK1124639A1 publication Critical patent/HK1124639A1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/4873—Cysteine endopeptidases (3.4.22), e.g. stem bromelain, papain, ficin, cathepsin H
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HK09103888.0A 2004-11-22 2009-04-27 Debriding composition from bromelain and methods of production thereof HK1124639A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IL16533404A IL165334A0 (en) 2004-11-22 2004-11-22 Debriding composition from bromelain and methods of producing same
PCT/IL2005/001236 WO2006054309A2 (fr) 2004-11-22 2005-11-22 Composition de parage a base de bromelaine et procedes de fabrication

Publications (1)

Publication Number Publication Date
HK1124639A1 true HK1124639A1 (en) 2009-07-17

Family

ID=36407550

Family Applications (1)

Application Number Title Priority Date Filing Date
HK09103888.0A HK1124639A1 (en) 2004-11-22 2009-04-27 Debriding composition from bromelain and methods of production thereof

Country Status (18)

Country Link
US (2) US8119124B2 (fr)
EP (1) EP1824775B1 (fr)
JP (1) JP5053096B2 (fr)
KR (1) KR101235544B1 (fr)
CN (1) CN101297033B (fr)
AU (1) AU2005305461B2 (fr)
BR (1) BRPI0518050A (fr)
CA (1) CA2587951C (fr)
DK (1) DK1824775T3 (fr)
ES (1) ES2389810T3 (fr)
HK (1) HK1124639A1 (fr)
IL (2) IL165334A0 (fr)
MX (1) MX2007006074A (fr)
NO (1) NO337096B1 (fr)
PL (1) PL1824775T3 (fr)
PT (1) PT1824775E (fr)
WO (1) WO2006054309A2 (fr)
ZA (1) ZA200704821B (fr)

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HUE052944T2 (hu) * 2010-06-25 2021-05-28 Shire Human Genetic Therapies Terápiás hatóanyagok központi idegrendszerbe juttatása
RU2013150536A (ru) 2011-05-12 2015-06-20 Смит & Невью Ортопедикс АГ Способ и топическая композиция для обработки ран, содержащая seaprose и его применение
GB201110777D0 (en) * 2011-06-24 2011-08-10 Aqua Bio Technology Asa Methods and uses
GB201110783D0 (en) 2011-06-24 2011-08-10 Aqua Bio Technology Asa Methods and uses
MX350145B (es) * 2011-07-20 2017-08-28 Mediwound Ltd Extracto proteolitico a partir de bromelaina para el tratamiento de trastornos del tejido conectivo.
WO2013096337A1 (fr) 2011-12-20 2013-06-27 Kci Licensing, Inc. Composition destinée au débridement enzymatique
EP2849777B1 (fr) 2012-05-11 2017-10-18 Smith & Nephew, Inc. Seaprose pour retirer un biofilm bactérien
CN104884079B (zh) * 2012-11-14 2021-02-12 史密夫和内修公司 稳定的嗜热菌蛋白酶水凝胶
US10238719B2 (en) 2014-10-10 2019-03-26 Rochal Industries, Llc Compositions and kits for enzymatic debridement and methods of using the same
LT6177B (lt) 2014-10-10 2015-07-27 Uab "Biocentras" Fermentų kompleksų išskyrimas iš steptomyces gougerotii 101, daugiafermentinių biopreparatų ruošimas bei taikymas
US9592280B2 (en) 2014-10-10 2017-03-14 Rochal Industries Llc Compositions and kits for enzymatic debridement and methods of using the same
US20160101166A1 (en) 2014-10-10 2016-04-14 Rochal Industries, Llp Compositions and kits for treating pruritus and methods of using the same
CN104857187A (zh) * 2015-04-28 2015-08-26 李正 一种菠萝蛋白酶烧伤组织愈合药物
NZ745240A (en) 2016-01-31 2022-12-23 Mediwound Ltd Debriding composition for treating wounds
AU2017252085B2 (en) * 2016-04-18 2021-09-16 Mediwound Ltd Methods of debridement of chronic wounds
WO2018020435A1 (fr) 2016-07-27 2018-02-01 Smith & Nephew, Inc. Utilisation de la thermolysine pour réduire ou éliminer les biofilms bactériens sur des surfaces
CN107913401A (zh) * 2016-10-08 2018-04-17 江阴市本特塞缪森生命科学研究院有限公司 胰蛋白酶产品及治疗妇科炎症的应用
US11413300B2 (en) 2017-01-30 2022-08-16 Smith & Nephew, Inc. Synergistic combination of thermolysin and an antibacterial agent to reduce or eliminate bacterial biofilms from surfaces
EP3860336A1 (fr) 2018-10-05 2021-08-11 Xenotherapeutics, Inc. Produits et procédés de xénotransplantation
US10883084B2 (en) 2018-10-05 2021-01-05 Xenotherapeutics, Inc. Personalized cells, tissues, and organs for transplantation from a humanized, bespoke, designated-pathogen free, (non-human) donor and methods and products relating to same
WO2020198397A1 (fr) 2019-03-25 2020-10-01 Xenotherapeutics, Inc. Cellules, tissus et organes personnalisés pour une transplantation à partir d'un donneur (non humain) humanisé, sur mesure, conçu sans pathogène, et procédés et produits associés
WO2023159123A1 (fr) * 2022-02-16 2023-08-24 Guild Associates Inc. Débridement des plaies à base d'enzymes immobilisées

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US4307081A (en) 1974-01-08 1981-12-22 Gerold K. V. Klein Enzyme mixture
US4226854A (en) 1974-01-08 1980-10-07 Gerold K. V. Klein Debridement of devitalized tissue with hydrolytic enzyme product
US4197291A (en) 1974-01-08 1980-04-08 Gerold K. V. Klein Hydrolytic enzyme material
US4329430A (en) * 1979-06-04 1982-05-11 Klein Gerold K V Enzyme mixture
US4320120A (en) 1979-10-22 1982-03-16 Zenyaku Kogyo Kabushiki Kaisha Extracts of Marsdenia cundurango Reichenbach fil
US4286064A (en) * 1979-11-05 1981-08-25 Riker Laboratories, Inc. Process for isolating active debriding agent from bromelain
US4361551A (en) 1979-11-05 1982-11-30 Riker Laboratories, Inc. Method of enzymatic debridement
WO1981001242A1 (fr) 1979-11-05 1981-05-14 Riker Laboratories Inc Procede de debridement enzymatique
GB8724728D0 (en) 1987-10-22 1987-11-25 Genzyme Corp Cysteine proteinase
CA2046802C (fr) 1990-08-15 2007-05-22 Donald Zane Fortney Compositions contenant de la protease produite par un vibrion et mode d'utilisation dans l'excision des debris et la guerison de plaies
AU676464B2 (en) * 1991-12-03 1997-03-13 Klein, Margaret L. Proteolytic mixture containing escharase and method of isolating same
IL103969A (en) * 1991-12-03 1997-01-10 Gerold K V Klein Proteolytic mixture containing escharase and method of isolating same
AU672986B2 (en) * 1992-06-30 1996-10-24 Cortecs Limited Use of enzymes, especially bromelain, in the treatment of diarrhoea
GB9313188D0 (en) * 1993-06-25 1993-08-11 Cortecs Ltd Medical use of enzymes
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US5858964A (en) 1995-04-14 1999-01-12 Yeda Research And Development Co. Ltd. Pharmaceutical compositions comprising synthetic peptide copolymer for prevention of GVHD
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US20020102253A1 (en) * 1997-02-25 2002-08-01 Mynott Tracey Lehanne Component of bromelain
JP2001513636A (ja) * 1997-02-25 2001-09-04 コルテクス（ユーケイ）リミティッド ブロメラインの成分
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GB9819138D0 (en) * 1998-09-02 1998-10-28 Cortecs Uk Ltd Nucleic acids and proteins from pineapple stem
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CA2483329C (fr) * 2002-04-23 2011-11-01 Mediwound, Ltd. Appareil et procedes d'incision de decharge enzymatique dans le syndrome de compartiment induit par une brulure
EP2048939A4 (fr) * 2006-08-17 2010-04-28 Monsanto Technology Llc Plantes transgéniques à caractères agronomiques renforcés
EP2036978A1 (fr) * 2007-09-14 2009-03-18 URSAPHARM Arzneimittel GmbH & Co. KG Préparation recombinante de fractions de broméline sélectionnées

Also Published As

Publication number Publication date
AU2005305461A1 (en) 2006-05-26
JP5053096B2 (ja) 2012-10-17
ZA200704821B (en) 2008-11-26
EP1824775B1 (fr) 2012-06-13
CA2587951C (fr) 2015-03-31
US8119124B2 (en) 2012-02-21
PL1824775T3 (pl) 2012-12-31
NO20073115L (no) 2007-08-13
CN101297033A (zh) 2008-10-29
US20120171187A1 (en) 2012-07-05
US20090148429A1 (en) 2009-06-11
NO337096B1 (no) 2016-01-18
WO2006054309A3 (fr) 2009-04-30
CA2587951A1 (fr) 2006-05-26
ES2389810T3 (es) 2012-10-31
IL183184A0 (en) 2007-09-20
CN101297033B (zh) 2012-05-30
EP1824775A4 (fr) 2011-01-26
MX2007006074A (es) 2007-10-04
WO2006054309A2 (fr) 2006-05-26
JP2008520651A (ja) 2008-06-19
US8540983B2 (en) 2013-09-24
DK1824775T3 (da) 2012-09-24
PT1824775E (pt) 2012-09-19
EP1824775A2 (fr) 2007-08-29
IL183184A (en) 2015-09-24
AU2005305461B2 (en) 2011-01-27
BRPI0518050A (pt) 2008-10-28
KR20070091285A (ko) 2007-09-10
IL165334A0 (en) 2006-01-15
KR101235544B1 (ko) 2013-02-21

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