HK1119950A1 - 採用 -羥基他莫西芬預防和治療乳腺癌的製劑 - Google Patents

採用 -羥基他莫西芬預防和治療乳腺癌的製劑

Info

Publication number
HK1119950A1
HK1119950A1 HK08113909.5A HK08113909A HK1119950A1 HK 1119950 A1 HK1119950 A1 HK 1119950A1 HK 08113909 A HK08113909 A HK 08113909A HK 1119950 A1 HK1119950 A1 HK 1119950A1
Authority
HK
Hong Kong
Prior art keywords
formulations
prevention
treatment
breast cancer
hydroxy tamoxifen
Prior art date
Application number
HK08113909.5A
Other languages
English (en)
Inventor
Dominique Salin-Drouin
Jacques Wepierre
Philippe Rouanet
Original Assignee
Besins Healthcare Lu Sarl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Besins Healthcare Lu Sarl filed Critical Besins Healthcare Lu Sarl
Publication of HK1119950A1 publication Critical patent/HK1119950A1/zh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
HK08113909.5A 2003-04-01 2006-06-28 採用 -羥基他莫西芬預防和治療乳腺癌的製劑 HK1119950A1 (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US45896303P 2003-04-01 2003-04-01

Publications (1)

Publication Number Publication Date
HK1119950A1 true HK1119950A1 (zh) 2009-03-20

Family

ID=33131847

Family Applications (2)

Application Number Title Priority Date Filing Date
HK06107310.2A HK1086193A1 (zh) 2003-04-01 2006-06-28 採用 -羥基他莫西芬預防和治療乳腺癌
HK08113909.5A HK1119950A1 (zh) 2003-04-01 2006-06-28 採用 -羥基他莫西芬預防和治療乳腺癌的製劑

Family Applications Before (1)

Application Number Title Priority Date Filing Date
HK06107310.2A HK1086193A1 (zh) 2003-04-01 2006-06-28 採用 -羥基他莫西芬預防和治療乳腺癌

Country Status (12)

Country Link
US (2) US7704516B2 (zh)
EP (3) EP1952810B1 (zh)
JP (1) JP5490346B2 (zh)
AU (1) AU2003294973B2 (zh)
CA (1) CA2519980C (zh)
ES (3) ES2456958T3 (zh)
HK (2) HK1086193A1 (zh)
IL (1) IL170807A (zh)
MX (1) MXPA05010597A (zh)
NO (1) NO333805B1 (zh)
NZ (1) NZ542499A (zh)
WO (1) WO2004087123A1 (zh)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60327363D1 (de) * 2002-12-18 2009-06-04 Besins Int Lab Verringerung der dichte des brustgewebes durch 4-hydroxy tamoxifen
CA2509660C (en) * 2002-12-18 2011-08-30 Bruno De Lignieres (Deceased) Treatment of mastalgia with 4-hydroxy tamoxifen
EP1952810B1 (en) * 2003-04-01 2014-01-08 Besins Healthcare Luxembourg SARL Treatment of breast cancer with 4-hydroxytamoxifen
JP4682129B2 (ja) * 2003-06-09 2011-05-11 アセンド セラピュティクス インコーポレイテッド ４−ヒドロキシタモキシフェンによる過剰瘢痕化の治療及び予防
US7968532B2 (en) * 2003-12-15 2011-06-28 Besins Healthcare Luxembourg Treatment of gynecomastia with 4-hydroxy tamoxifen
EP1579856A1 (en) * 2004-03-22 2005-09-28 Laboratoires Besins International Treatment and prevention of benign breast disease with 4-hydroxy tamoxifen
EP1579857A1 (en) * 2004-03-22 2005-09-28 Laboratoires Besins International Chemically stable compositions of 4-hydroxy tamoxifen
JP5072588B2 (ja) * 2004-03-22 2012-11-14 ラボラトワール ブザン アンテルナスィヨナル ４−ヒドロキシタモキシフェンを用いた良性乳房疾患の治療および予防
US7507769B2 (en) 2004-03-22 2009-03-24 Laboratoires Besins International Treatment and prevention of benign breast disease with 4-hydroxy tamoxifen
DE602005011314D1 (de) * 2004-10-14 2009-01-08 Besins Int Lab 4-hydroxytamoxifengel-formulierungen
EP1647271A1 (en) * 2004-10-14 2006-04-19 Laboratoires Besins International 4-Hydroxy tamoxifen gel formulations
EP2147674A1 (en) * 2008-07-24 2010-01-27 Besins Healthcare Transdermal pharmaceutical compositions comprising danazol
US10080760B2 (en) * 2009-10-27 2018-09-25 Besins Healthcare Luxembourg Sarl Transdermal pharmaceutical compositions comprising active agents
BR112016026459B1 (pt) * 2014-05-12 2022-09-27 Quest Diagnostics Investments Incorporated Métodos para determinar a quantidade de norendoxifeno e para determinar a quantidade de tamoxifeno e metabólitos do mesmo em uma amostra humana por espectrometria de massas
KR101571098B1 (ko) 2014-07-16 2015-11-23 건국대학교 산학협력단 타목시펜 및 메틸설포닐메탄을 유효성분으로 포함하는 암 질환 예방 또는 치료용 약학 조성물
JP6645431B2 (ja) * 2014-08-27 2020-02-14 東洋紡株式会社 低誘電接着剤組成物
US10278976B2 (en) 2014-12-12 2019-05-07 Mira Dx, Inc. Methods for treating or preventing cancer in a KRAS-variant patient and for diagnosing risk of developing multiple primary breast tumors
IL262643B2 (en) 2016-04-29 2023-09-01 Univ Texas Targeted measurement of hormone receptor-associated transcriptional activity
AU2018329202B2 (en) 2017-09-11 2022-10-27 Atossa Therapeutics, Inc. Methods for making and using endoxifen
WO2019172109A1 (ja) 2018-03-07 2019-09-12 東亞合成株式会社 接着剤組成物及びこれを用いた接着剤層付き積層体
US20210299094A1 (en) * 2018-07-24 2021-09-30 Cornell University Methods of upregulating tiparp as anticancer strategies

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2558373B1 (fr) * 1984-01-20 1987-07-03 Mauvais Jarvis Pierre Medicament antioestrogene a base de 4-hydroxytamoxifene pour administration percutanee
EP0287690B1 (de) * 1987-04-21 1992-09-02 HEUMANN PHARMA GMBH & CO Stabile Lösungsmitteladdukte von Z-1-(p-beta-Dimethylamino-ethoxyphenyl)-1-(p-hydroxyphenyl)-2-phenylbut-1-en
US5045553A (en) 1987-06-24 1991-09-03 Fujisawa Pharmaceutical Company, Ltd. Pharmaceutical composition for percutaneous drug absorption and percutaneous drug absorption promoter
DE3836862A1 (de) 1988-10-27 1990-05-03 Schering Ag Mittel zur transdermalen applikation von steroidhormonen
US5189212A (en) 1990-09-07 1993-02-23 University Of Georgia Research Foundation, Inc. Triarylethylene carboxylic acids with estrogenic activity
TW218849B (zh) * 1991-05-17 1994-01-11 Bristol Myers Squibb Co
US5613958A (en) 1993-05-12 1997-03-25 Pp Holdings Inc. Transdermal delivery systems for the modulated administration of drugs
DE4407742C1 (de) 1994-03-08 1995-06-22 Hexal Pharma Gmbh Transdermales System in Form eines Pflasters mit einem Tamoxifen-Derivat
US5720963A (en) * 1994-08-26 1998-02-24 Mary Kay Inc. Barrier disruption treatments for structurally deteriorated skin
JP2001500841A (ja) * 1996-03-29 2001-01-23 エス ヴェー パテントフェアヴェアツングス ゲゼルシャフト ミット ベシュレンクテル ハフツンク 障害された皮下結合脂肪組織、とりわけ脂肪性浮腫の場合における皮膚を引きしめ滑らかにするための化粧品および化粧用組成物
DE69813624D1 (de) 1997-12-23 2003-05-22 Hexal Ag Gemisch und pharmazeutische zubereitung enthaltend z-4-hydroxytamoxifen und cyclodextrin
US6013270A (en) * 1998-04-20 2000-01-11 The Procter & Gamble Company Skin care kit
ATE290856T1 (de) 1999-12-16 2005-04-15 Dermatrends Inc Hydroxide freisetzende verbindungen zum verbessern der hautdurchlässigkeit
DE10033853A1 (de) 2000-07-12 2002-01-31 Hexal Ag Transdermales therapeutisches System mit hochdispersem Siliziumdioxid
US20040198706A1 (en) 2003-03-11 2004-10-07 Carrara Dario Norberto R. Methods and formulations for transdermal or transmucosal application of active agents
US6503894B1 (en) 2000-08-30 2003-01-07 Unimed Pharmaceuticals, Inc. Pharmaceutical composition and method for treating hypogonadism
US20030175329A1 (en) 2001-10-04 2003-09-18 Cellegy Pharmaceuticals, Inc. Semisolid topical hormonal compositions and methods for treatment
DE60139625D1 (de) 2001-12-07 2009-10-01 Besins Int Belgique Gel oder Lösung enthaltend Dihydrotestosterone, deren Herstellungsverfahren und Verwendung
DE60327363D1 (de) * 2002-12-18 2009-06-04 Besins Int Lab Verringerung der dichte des brustgewebes durch 4-hydroxy tamoxifen
CA2509660C (en) * 2002-12-18 2011-08-30 Bruno De Lignieres (Deceased) Treatment of mastalgia with 4-hydroxy tamoxifen
EP1952810B1 (en) 2003-04-01 2014-01-08 Besins Healthcare Luxembourg SARL Treatment of breast cancer with 4-hydroxytamoxifen
JP4682129B2 (ja) 2003-06-09 2011-05-11 アセンド セラピュティクス インコーポレイテッド ４−ヒドロキシタモキシフェンによる過剰瘢痕化の治療及び予防
US7968532B2 (en) 2003-12-15 2011-06-28 Besins Healthcare Luxembourg Treatment of gynecomastia with 4-hydroxy tamoxifen
US7507769B2 (en) 2004-03-22 2009-03-24 Laboratoires Besins International Treatment and prevention of benign breast disease with 4-hydroxy tamoxifen
EP1579856A1 (en) 2004-03-22 2005-09-28 Laboratoires Besins International Treatment and prevention of benign breast disease with 4-hydroxy tamoxifen
EP1579857A1 (en) 2004-03-22 2005-09-28 Laboratoires Besins International Chemically stable compositions of 4-hydroxy tamoxifen
EP1647271A1 (en) 2004-10-14 2006-04-19 Laboratoires Besins International 4-Hydroxy tamoxifen gel formulations

Also Published As

Publication number Publication date
JP2006514967A (ja) 2006-05-18
EP1608353B1 (en) 2014-04-30
US8475814B2 (en) 2013-07-02
US20050031695A1 (en) 2005-02-10
EP1608353A1 (en) 2005-12-28
JP5490346B2 (ja) 2014-05-14
IL170807A (en) 2014-08-31
EP1941871A1 (en) 2008-07-09
EP1941871B1 (en) 2014-01-08
MXPA05010597A (es) 2006-03-09
AU2003294973B2 (en) 2010-05-13
CA2519980C (en) 2012-04-10
ES2456957T3 (es) 2014-04-24
NO20054526L (no) 2005-09-30
AU2003294973A1 (en) 2004-10-25
ES2483896T3 (es) 2014-08-08
US7704516B2 (en) 2010-04-27
NO333805B1 (no) 2013-09-16
CA2519980A1 (en) 2004-10-14
ES2456958T3 (es) 2014-04-24
HK1086193A1 (zh) 2006-09-15
EP1952810B1 (en) 2014-01-08
NZ542499A (en) 2008-10-31
WO2004087123A1 (en) 2004-10-14
US20090186944A1 (en) 2009-07-23
EP1952810A1 (en) 2008-08-06

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Legal Events

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PE Patent expired

Effective date: 20231216