HK1119678A1 - Substituted 4-phenyl piperidines for use as renin inhibitors - Google Patents

Substituted 4-phenyl piperidines for use as renin inhibitors

Info

Publication number
HK1119678A1
HK1119678A1 HK08111638.7A HK08111638A HK1119678A1 HK 1119678 A1 HK1119678 A1 HK 1119678A1 HK 08111638 A HK08111638 A HK 08111638A HK 1119678 A1 HK1119678 A1 HK 1119678A1
Authority
HK
Hong Kong
Prior art keywords
substituted
renin inhibitors
phenyl piperidines
piperidines
phenyl
Prior art date
Application number
HK08111638.7A
Other languages
English (en)
Inventor
Peter Herold
Robert Mah
Stefan Stutz
Vincenzo Tschinke
Aleksandar Stojanovic
Dirk Behnke
Nathalie Jotterand
Stjepan Jelakovic
Original Assignee
Speedel Experimenta Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Speedel Experimenta Ag filed Critical Speedel Experimenta Ag
Publication of HK1119678A1 publication Critical patent/HK1119678A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/06Antiglaucoma agents or miotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Hospice & Palliative Care (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
HK08111638.7A 2006-10-04 2008-10-22 Substituted 4-phenyl piperidines for use as renin inhibitors HK1119678A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP06121772A EP1911758A1 (en) 2006-10-04 2006-10-04 Phenyl piperidine derivatives for use as renin inhibitors
PCT/EP2007/060510 WO2008040764A1 (en) 2006-10-04 2007-10-03 Substituted 4-phenyl piperidines for use as renin inhibitors

Publications (1)

Publication Number Publication Date
HK1119678A1 true HK1119678A1 (en) 2009-03-13

Family

ID=37946086

Family Applications (1)

Application Number Title Priority Date Filing Date
HK08111638.7A HK1119678A1 (en) 2006-10-04 2008-10-22 Substituted 4-phenyl piperidines for use as renin inhibitors

Country Status (18)

Country Link
US (1) US7625893B2 (da)
EP (2) EP1911758A1 (da)
JP (1) JP2009532443A (da)
CN (1) CN101415703B (da)
AR (1) AR063124A1 (da)
AT (1) ATE425159T1 (da)
BR (1) BRPI0716114A2 (da)
CA (1) CA2642455A1 (da)
DE (1) DE602007000679D1 (da)
DK (1) DK1934207T3 (da)
ES (1) ES2322629T3 (da)
HK (1) HK1119678A1 (da)
IL (1) IL193476A0 (da)
PL (1) PL1934207T3 (da)
PT (1) PT1934207E (da)
SI (1) SI1934207T1 (da)
TW (1) TW200831499A (da)
WO (1) WO2008040764A1 (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008535825A (ja) * 2005-03-31 2008-09-04 シュペーデル・エクスペリメンタ・アーゲー レニン阻害剤としての3,4,5−置換ピペリジン
TW200932241A (en) * 2007-12-05 2009-08-01 Speedel Experimenta Ag Organic compounds
KR20100095605A (ko) 2007-12-19 2010-08-31 다이닛본 스미토모 세이야꾸 가부시끼가이샤 바이시클릭 헤테로시클릭 유도체
BRPI0910991A2 (pt) * 2008-04-02 2016-01-19 Novartis Ag piperidinas substituídas como compostos terapêuticos
EP2447264A4 (en) 2009-06-24 2012-12-12 Dainippon Sumitomo Pharma Co N-SUBSTITUTED CYCLIC AMINO DERIVATIVE

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5194605A (en) * 1989-12-08 1993-03-16 Merck & Co., Inc. Cyclic renin inhibitors containing 2-substituted (3S,4S)-4-amino-5-cyclohexyl-3-hydroxy pentanoic acid, 2-substituted (3S,4S)-5-cyclohexyl-3,4-di-hydroxy pentanoic acid or 2-substituted (4S,5S)-5-amino-6-cyclohexyl-4-hydroxyhexanoic acid or its analogs
EP0432975A1 (en) * 1989-12-08 1991-06-19 Merck & Co. Inc. Cyclic renin inhibitors
US6376672B1 (en) * 1999-04-27 2002-04-23 Hoffmann-La Roche Inc. Naphthalenylmethoxypiperidines as renin inhibitors
US20040204455A1 (en) * 2003-04-10 2004-10-14 Cody Wayne Livingston Piperidine derivative rennin inhibitors
TW200613274A (en) * 2004-07-09 2006-05-01 Speedel Experimenta Ag Organic compounds

Also Published As

Publication number Publication date
US20090088426A1 (en) 2009-04-02
US7625893B2 (en) 2009-12-01
ATE425159T1 (de) 2009-03-15
BRPI0716114A2 (pt) 2013-09-24
SI1934207T1 (sl) 2009-08-31
CA2642455A1 (en) 2008-04-10
JP2009532443A (ja) 2009-09-10
EP1934207B1 (en) 2009-03-11
IL193476A0 (en) 2009-05-04
EP1934207A1 (en) 2008-06-25
CN101415703A (zh) 2009-04-22
DK1934207T3 (da) 2009-06-02
EP1911758A1 (en) 2008-04-16
PL1934207T3 (pl) 2009-10-30
ES2322629T3 (es) 2009-06-23
WO2008040764A1 (en) 2008-04-10
TW200831499A (en) 2008-08-01
PT1934207E (pt) 2009-05-21
CN101415703B (zh) 2012-04-25
DE602007000679D1 (de) 2009-04-23
AR063124A1 (es) 2008-12-30

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