HK1119395A1 - Conjugates of hydroxyalkyl starch and an active substance, prepared by chemical ligation via thiazolidine - Google Patents

Conjugates of hydroxyalkyl starch and an active substance, prepared by chemical ligation via thiazolidine

Info

Publication number
HK1119395A1
HK1119395A1 HK08111204.1A HK08111204A HK1119395A1 HK 1119395 A1 HK1119395 A1 HK 1119395A1 HK 08111204 A HK08111204 A HK 08111204A HK 1119395 A1 HK1119395 A1 HK 1119395A1
Authority
HK
Hong Kong
Prior art keywords
conjugates
active substance
hydroxyalkyl starch
prepared
chemical ligation
Prior art date
Application number
HK08111204.1A
Other languages
English (en)
Inventor
Norbert Zander
Helmut Knoller
Original Assignee
Fresenius Kabi De Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fresenius Kabi De Gmbh filed Critical Fresenius Kabi De Gmbh
Publication of HK1119395A1 publication Critical patent/HK1119395A1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/61—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B31/00—Preparation of derivatives of starch
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Materials Engineering (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Polymers & Plastics (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Oncology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Peptides Or Proteins (AREA)
HK08111204.1A 2005-09-12 2008-10-09 Conjugates of hydroxyalkyl starch and an active substance, prepared by chemical ligation via thiazolidine HK1119395A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP05019768A EP1762250A1 (en) 2005-09-12 2005-09-12 Conjugates of hydroxyalkyl starch and an active substance, prepared by chemical ligation via thiazolidine
PCT/EP2006/008858 WO2007031266A2 (en) 2005-09-12 2006-09-12 Conjugates of hydroxyalkyl starch and an active substance, prepared by chemical ligation via thiazolidine

Publications (1)

Publication Number Publication Date
HK1119395A1 true HK1119395A1 (en) 2009-03-06

Family

ID=35426984

Family Applications (1)

Application Number Title Priority Date Filing Date
HK08111204.1A HK1119395A1 (en) 2005-09-12 2008-10-09 Conjugates of hydroxyalkyl starch and an active substance, prepared by chemical ligation via thiazolidine

Country Status (15)

Country Link
US (1) US20080207562A1 (xx)
EP (2) EP1762250A1 (xx)
JP (1) JP5242398B2 (xx)
KR (1) KR20080065602A (xx)
CN (2) CN101262889B (xx)
AT (1) ATE543515T1 (xx)
AU (1) AU2006291527B2 (xx)
BR (1) BRPI0615732A2 (xx)
CA (1) CA2619036A1 (xx)
EA (1) EA013910B1 (xx)
ES (1) ES2382303T3 (xx)
HK (1) HK1119395A1 (xx)
IL (1) IL189466A0 (xx)
WO (1) WO2007031266A2 (xx)
ZA (1) ZA200802252B (xx)

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DE10209821A1 (de) * 2002-03-06 2003-09-25 Biotechnologie Ges Mittelhesse Kopplung von Proteinen an ein modifiziertes Polysaccharid
KR101174510B1 (ko) * 2002-09-11 2012-08-16 프레제니우스 카비 도이치란트 게엠베하 하이드록시알킬전분화 폴리펩티드, 특히 하이드록시알킬전분화 에리트로포이에틴
WO2005014655A2 (en) 2003-08-08 2005-02-17 Fresenius Kabi Deutschland Gmbh Conjugates of hydroxyalkyl starch and a protein
SG145746A1 (en) * 2003-08-08 2008-09-29 Fresenius Kabi De Gmbh Conjugates of hydroxyalkyl starch and g-csf
EP2336192A1 (en) 2004-03-11 2011-06-22 Fresenius Kabi Deutschland GmbH Conjugates of hydroxyalkyl starch and a protein, prepared by reductive amination
ES2390885T3 (es) * 2004-03-11 2012-11-19 Fresenius Kabi Deutschland Gmbh Conjugados de hidroxialquilalmidón y una proteína
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TWI582097B (zh) 2010-03-23 2017-05-11 Ｖｉｉｖ醫療保健公司 製備胺甲醯吡啶酮衍生物及中間體之方法
JP2014521594A (ja) 2011-05-25 2014-08-28 アミリン・ファーマシューティカルズ，リミテッド・ライアビリティ・カンパニー 長持続期間デュアルホルモンコンジュゲート
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CN113214620B (zh) * 2021-05-25 2022-06-21 湖北工业大学 一种环氧基有机改性蒙脱土的制备方法及应用
CN115385973B (zh) * 2022-07-13 2023-06-06 康龙化成(宁波)科技发展有限公司 寡聚核酸-四氢噻唑类化合物在基因编码化合物库合成上的应用
CN116448996B (zh) * 2023-03-22 2023-11-21 卡秋(江苏)生物科技有限公司 一种串珠结构的多聚酶-抗体复合物的制备方法

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Also Published As

Publication number Publication date
JP2009507973A (ja) 2009-02-26
EA013910B1 (ru) 2010-08-30
KR20080065602A (ko) 2008-07-14
JP5242398B2 (ja) 2013-07-24
WO2007031266A2 (en) 2007-03-22
BRPI0615732A2 (pt) 2011-05-24
AU2006291527B2 (en) 2012-03-22
CN102492047A (zh) 2012-06-13
WO2007031266A3 (en) 2007-09-20
EP1933878B1 (en) 2012-02-01
EA200800822A1 (ru) 2008-08-29
CN101262889B (zh) 2013-02-06
ATE543515T1 (de) 2012-02-15
ES2382303T3 (es) 2012-06-07
AU2006291527A1 (en) 2007-03-22
ZA200802252B (en) 2009-08-26
EP1933878A2 (en) 2008-06-25
IL189466A0 (en) 2008-08-07
US20080207562A1 (en) 2008-08-28
EP1762250A1 (en) 2007-03-14
CA2619036A1 (en) 2007-03-22
CN101262889A (zh) 2008-09-10

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